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The map label for this gene is exoB [H]

Identifier: 118581378

GI number: 118581378

Start: 3242597

End: 3243592

Strand: Direct

Name: exoB [H]

Synonym: Ppro_2973

Alternate gene names: 118581378

Gene position: 3242597-3243592 (Clockwise)

Preceding gene: 118581377

Following gene: 118581387

Centisome position: 80.9

GC content: 65.16

Gene sequence:

>996_bases
ATGTCTGAAACAATCCTCGTTACCGGCGGCTGCGGCTACATCGGCAGCCACGTTGTCCGTCAACTGTCCGAATCGGGCCA
CCGGGTGGTGGTGTACGACAACCTCTCCACCGGCTTTCCCAATGCCCTTGTAAACGGGGAGGAGCTGATCCTGGCCGACC
TGAGCGACACGGCGGCCCTGAACGACGCCTTCCAGAGCCACCGATTCTCCACCGTGCTGCACTTTGCCGCTGCCATCATC
GCCCCTGAATCGGTCTCGCTGCCGTTGAAATACTACGGCAACAACACCCGCAACACCCTGGGACTGCTGGAGACATGCGT
CAGGCATCGCGTCAAGCGCTTCATCTTCTCCAGCACCGCCGCCGTGTACGGCTTTCCCGAGGGAGGAGTGGCCGCCGAGG
AGAGCGTCCTGGCCCCCATCAACCCCTACGGCACCTCCAAGCTGATGAGCGAGTGGATGCTCAGGGACACCTGCGCTGCC
CACGACATGAAGTACGTGGCCCTGCGCTACTTCAACGTGGCCGGTGCCGACCCCCTGGCCCGCATGGGGCAGCGCACCCC
CGAGGCGACCCACCTGATCAAGGTGGCCTGCCAGGCCGCCCTGGGGATGCGGGAACGCATTGCCATCTACGGCACCGACT
ACCCCACCCCCGACGGCACCGGCGTACGCGACTACATCCACATCGAGGATTTGGCCTCGGCCCACCTGCACGCCCTCACG
TACCTGGAGCAGGGGGGAGAGCCGACCGCCATGAACGTGGGCTACGGTCGCGGCAGCAGCGTAAGAGAGGTCCTGAATCT
GGTGAAAGAGGTAAGCGGCGTGGATTTCAGGGTGGTGGAGGAGGATCGCCGCCCCGGAGACCCGGCCTCGCTGGTTGCCC
GGGCGGAGAGGATCGGCGAACTCACCGGCTGGAAGCCCAGGCACAATGACCTGCGCGGCATCATCGCCGACGCCTGGCGG
TGGGAGAGCAAGCTGGCGGCACTGCCGAAACAGTGA

Upstream 100 bases:

>100_bases
CGCTCGCTGAAGAACATCCAGAAATACCTGTAGTTCATCCCAATCAAGGGGCGGCCCCCGCGGGGGAAGCAGATTCGCCG
TCCCGCCTCAAGGAATGCCC

Downstream 100 bases:

>100_bases
CCGTTGCCGAGCGAAAAGAGAGAAGGGCGGCCGTCATCCCGACAGCCGCCCTTCTCTTGTCATCCTCCGGGACATTACCC
GCGCACCCCTGAATCAGCCG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSETILVTGGCGYIGSHVVRQLSESGHRVVVYDNLSTGFPNALVNGEELILADLSDTAALNDAFQSHRFSTVLHFAAAII
APESVSLPLKYYGNNTRNTLGLLETCVRHRVKRFIFSSTAAVYGFPEGGVAAEESVLAPINPYGTSKLMSEWMLRDTCAA
HDMKYVALRYFNVAGADPLARMGQRTPEATHLIKVACQAALGMRERIAIYGTDYPTPDGTGVRDYIHIEDLASAHLHALT
YLEQGGEPTAMNVGYGRGSSVREVLNLVKEVSGVDFRVVEEDRRPGDPASLVARAERIGELTGWKPRHNDLRGIIADAWR
WESKLAALPKQ

Sequences:

>Translated_331_residues
MSETILVTGGCGYIGSHVVRQLSESGHRVVVYDNLSTGFPNALVNGEELILADLSDTAALNDAFQSHRFSTVLHFAAAII
APESVSLPLKYYGNNTRNTLGLLETCVRHRVKRFIFSSTAAVYGFPEGGVAAEESVLAPINPYGTSKLMSEWMLRDTCAA
HDMKYVALRYFNVAGADPLARMGQRTPEATHLIKVACQAALGMRERIAIYGTDYPTPDGTGVRDYIHIEDLASAHLHALT
YLEQGGEPTAMNVGYGRGSSVREVLNLVKEVSGVDFRVVEEDRRPGDPASLVARAERIGELTGWKPRHNDLRGIIADAWR
WESKLAALPKQ
>Mature_330_residues
SETILVTGGCGYIGSHVVRQLSESGHRVVVYDNLSTGFPNALVNGEELILADLSDTAALNDAFQSHRFSTVLHFAAAIIA
PESVSLPLKYYGNNTRNTLGLLETCVRHRVKRFIFSSTAAVYGFPEGGVAAEESVLAPINPYGTSKLMSEWMLRDTCAAH
DMKYVALRYFNVAGADPLARMGQRTPEATHLIKVACQAALGMRERIAIYGTDYPTPDGTGVRDYIHIEDLASAHLHALTY
LEQGGEPTAMNVGYGRGSSVREVLNLVKEVSGVDFRVVEEDRRPGDPASLVARAERIGELTGWKPRHNDLRGIIADAWRW
ESKLAALPKQ

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=38.7755102040816, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=38.7755102040816, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=38.7755102040816, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI7657641, Length=322, Percent_Identity=25.776397515528, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI42516563, Length=314, Percent_Identity=25.4777070063694, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1786974, Length=340, Percent_Identity=37.9411764705882, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1790049, Length=267, Percent_Identity=27.3408239700375, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788353, Length=347, Percent_Identity=26.8011527377522, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI48994969, Length=345, Percent_Identity=27.8260869565217, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71982035, Length=340, Percent_Identity=37.0588235294118, Blast_Score=201, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI71982038, Length=342, Percent_Identity=36.8421052631579, Blast_Score=200, Evalue=9e-52,
Organism=Caenorhabditis elegans, GI17568069, Length=246, Percent_Identity=28.8617886178862, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115532424, Length=344, Percent_Identity=24.7093023255814, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=331, Percent_Identity=24.1691842900302, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=341, Percent_Identity=37.5366568914956, Blast_Score=211, Evalue=1e-55,
Organism=Drosophila melanogaster, GI19923002, Length=340, Percent_Identity=37.9411764705882, Blast_Score=211, Evalue=6e-55,
Organism=Drosophila melanogaster, GI21356223, Length=315, Percent_Identity=25.0793650793651, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36185; Mature: 36054

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETILVTGGCGYIGSHVVRQLSESGHRVVVYDNLSTGFPNALVNGEELILADLSDTAAL
CCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCEEEEEECCCHHHH
NDAFQSHRFSTVLHFAAAIIAPESVSLPLKYYGNNTRNTLGLLETCVRHRVKRFIFSSTA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCH
AVYGFPEGGVAAEESVLAPINPYGTSKLMSEWMLRDTCAAHDMKYVALRYFNVAGADPLA
HEEECCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHEEHHEEECCCCCCHHH
RMGQRTPEATHLIKVACQAALGMRERIAIYGTDYPTPDGTGVRDYIHIEDLASAHLHALT
HHCCCCCHHHHHHHHHHHHHHCCHHEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHH
YLEQGGEPTAMNVGYGRGSSVREVLNLVKEVSGVDFRVVEEDRRPGDPASLVARAERIGE
HHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHH
LTGWKPRHNDLRGIIADAWRWESKLAALPKQ
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SETILVTGGCGYIGSHVVRQLSESGHRVVVYDNLSTGFPNALVNGEELILADLSDTAAL
CCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCEEEEEECCCHHHH
NDAFQSHRFSTVLHFAAAIIAPESVSLPLKYYGNNTRNTLGLLETCVRHRVKRFIFSSTA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCH
AVYGFPEGGVAAEESVLAPINPYGTSKLMSEWMLRDTCAAHDMKYVALRYFNVAGADPLA
HEEECCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHEEHHEEECCCCCCHHH
RMGQRTPEATHLIKVACQAALGMRERIAIYGTDYPTPDGTGVRDYIHIEDLASAHLHALT
HHCCCCCHHHHHHHHHHHHHHCCHHEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHH
YLEQGGEPTAMNVGYGRGSSVREVLNLVKEVSGVDFRVVEEDRRPGDPASLVARAERIGE
HHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHH
LTGWKPRHNDLRGIIADAWRWESKLAALPKQ
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]