BacMap

Definition	Pelobacter propionicus DSM 2379 chromosome, complete genome.
Accession	NC_008609
Length	4,008,000

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The map label for this gene is ftsH

Identifier: 118581289

GI number: 118581289

Start: 3155177

End: 3157048

Strand: Direct

Name: ftsH

Synonym: Ppro_2884

Alternate gene names: 118581289

Gene position: 3155177-3157048 (Clockwise)

Preceding gene: 118581261

Following gene: 118581290

Centisome position: 78.72

GC content: 63.25

Gene sequence:

>1872_bases
ATGAACCAATCCTTCTGGAGACCGCTGTTCGCCATACTCCTGTTCATGCTGGTCTTTCATCTCACCAACATCTTCTTTGC
GCAACAGGGCGCCCAGGTGGCCCAGATCAGCTACAGCCGCCTGCGCGCTGAACTGGCTCAAGACAACATCAAAAAGATAA
CCCTCAAGGGGACGGCTGTTACGGGCGAGTTTCGGGGCAAGACCAGGGTAAGCGCCCTGGTCCAGGGCAAGGAGCAGCAG
CGCGAGTTCACCGGCTTCAGCAGTGTCCTGCCGACCATCGACGACCAGACCCTGGTGCCGGAACTGATGGCGCGCAAGGT
GGAGGTGAGCGCCCTGTCCACGGAGACCCCTCTGCTGCTCAATGCCCTGATCTACGTGGCGCCCTGGGTGATCCTGATCG
CCATCTGGTGGGTGGGGATGCGCTCCATGCGCAGCCAGGGGCCGAGCGGGATGATGGGCGGCTTTTCCCGCTCCGGGGCA
AAGGCGTATCTGGCAGGTGACAAGATGGCCGTGTCTTTCAAGGATGTGGCCGGCATGGAGGACAGCAAGCAGGAGCTGAA
GGAGGTCGTGGACTATTTGCGCAATCCCAAGCAGTTCGCCCGCATCGGCGGCAAGGTTCCCAAGGGGGTTCTGCTGGTGG
GACCTCCGGGGACCGGCAAGACGCTCCTGGCCCGGGCGGTGGCCGGTGAGGCGGGAGTGGCCTTTTTCAGCATCTCCGCT
TCCCAATTCATCGAGATGTTTGTGGGGGTCGGCGCCAGCCGGGTGCGCGATCTGTTTACCAATGCCAAGAAGGCCGCTCC
CAGCATCGTCTTCATCGACGAACTGGATGCCGTCGGTCGCAGTCGAGGCGCCGGTTTCGGTGGTGGCCATGACGAGCGGG
AGCAGACCCTGAACCAGCTCCTGTCGGAGATGGACGGTTTCGACCAGCACGAGGAGGTCATCGTGCTGGCCGCCACCAAC
CGCCCCGATGTACTTGACCCGGCCCTGCTGCGCCCCGGCCGCTTCGACCGGCACGTAGTGATCGAGCGGCCGGACTGGCG
CGATCGGGAGAAGATCCTCCAAGTCCACGTGCGCAAGATCACCATGAACGGCAGGATCGACCTGGGGGTGATTGCCCGCG
GCACCCCCGGCATGACCGGCGCCGACCTTGAAAGCCTGGTCAACGAGGCAGCCATCCTGGCCTCGCGCGAGAACGCGGCC
GCGGTCACCATGGAGCATCTGGAAAAGGCCAAGGACAAGATCCTGATGGGAAGCGAGCGCAGGATGATCATCTCTTTGGA
AGAGAAGCGCATCACCGCCTACCACGAGGCCGGCCATACCCTGGTGGCCAGACTGCTCCCCGGCACCGACCCGATCCACA
AGGTGACCATCATCCCCCACGGCATGGCCCTGGGGGTGACCCAGCAACTCCCCGAGGACGACCGTTACCACTATCCCCAG
AGCTATCTGGAAAATCGGCTGGTGGTAGCCATGGGGGGGCGAGTGGCGGAGCGGCTTGCGTTTGGCGAGGTCTCCAGTGG
TGCCCAGGGGGATTTGAAACAGGTTACTTCCCTGGCGGAGAAGATGGTCTGTCAATGGGGGATGAGTGAAAAGGTGGGCG
GGATGACCTTCAGCCGGGGAGAGGAACACCCCTTCCTGGGGATGAAGCTGGCCGAGGAGAAGACCTTTTCCGAGGCCATG
GCCTGGCGCATCGACCAGGAGATAGCGGCCTTCATCACCAGAGCGGAGCAGCGCGCCGGTGACCTTCTGTCCGCCAATCG
CGAGCGACTGGACCTTTTGGCCCAGGCCCTGCAGGACGAGGAAACCCTGGACGGTAGCCGGGTTGACGAGATCATCGGTT
CGCTCAACACGGCTCAGGCGCCTCCCCCCTGA

Upstream 100 bases:

>100_bases
GCAACGCTGTGGCCACTCCACCGAAATTCTTGTGAAATACGCGGATAAGGATACACTATAGCTGCCCCTGTTCCGATTGA
TAATCACGAGGTTGTGGATC

Downstream 100 bases:

>100_bases
CCCCGATGAGGAGTGAGTTATTCAGGGGGCCGGTTCCGCCGCGGGATCGGCTCTCTTTATTTCCGGGCATTGCCTTGCTT
CCAGGCGTTTCCTCCGTATA

Product: ATP-dependent metalloprotease FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MNQSFWRPLFAILLFMLVFHLTNIFFAQQGAQVAQISYSRLRAELAQDNIKKITLKGTAVTGEFRGKTRVSALVQGKEQQ
REFTGFSSVLPTIDDQTLVPELMARKVEVSALSTETPLLLNALIYVAPWVILIAIWWVGMRSMRSQGPSGMMGGFSRSGA
KAYLAGDKMAVSFKDVAGMEDSKQELKEVVDYLRNPKQFARIGGKVPKGVLLVGPPGTGKTLLARAVAGEAGVAFFSISA
SQFIEMFVGVGASRVRDLFTNAKKAAPSIVFIDELDAVGRSRGAGFGGGHDEREQTLNQLLSEMDGFDQHEEVIVLAATN
RPDVLDPALLRPGRFDRHVVIERPDWRDREKILQVHVRKITMNGRIDLGVIARGTPGMTGADLESLVNEAAILASRENAA
AVTMEHLEKAKDKILMGSERRMIISLEEKRITAYHEAGHTLVARLLPGTDPIHKVTIIPHGMALGVTQQLPEDDRYHYPQ
SYLENRLVVAMGGRVAERLAFGEVSSGAQGDLKQVTSLAEKMVCQWGMSEKVGGMTFSRGEEHPFLGMKLAEEKTFSEAM
AWRIDQEIAAFITRAEQRAGDLLSANRERLDLLAQALQDEETLDGSRVDEIIGSLNTAQAPPP

Sequences:

>Translated_623_residues
MNQSFWRPLFAILLFMLVFHLTNIFFAQQGAQVAQISYSRLRAELAQDNIKKITLKGTAVTGEFRGKTRVSALVQGKEQQ
REFTGFSSVLPTIDDQTLVPELMARKVEVSALSTETPLLLNALIYVAPWVILIAIWWVGMRSMRSQGPSGMMGGFSRSGA
KAYLAGDKMAVSFKDVAGMEDSKQELKEVVDYLRNPKQFARIGGKVPKGVLLVGPPGTGKTLLARAVAGEAGVAFFSISA
SQFIEMFVGVGASRVRDLFTNAKKAAPSIVFIDELDAVGRSRGAGFGGGHDEREQTLNQLLSEMDGFDQHEEVIVLAATN
RPDVLDPALLRPGRFDRHVVIERPDWRDREKILQVHVRKITMNGRIDLGVIARGTPGMTGADLESLVNEAAILASRENAA
AVTMEHLEKAKDKILMGSERRMIISLEEKRITAYHEAGHTLVARLLPGTDPIHKVTIIPHGMALGVTQQLPEDDRYHYPQ
SYLENRLVVAMGGRVAERLAFGEVSSGAQGDLKQVTSLAEKMVCQWGMSEKVGGMTFSRGEEHPFLGMKLAEEKTFSEAM
AWRIDQEIAAFITRAEQRAGDLLSANRERLDLLAQALQDEETLDGSRVDEIIGSLNTAQAPPP
>Mature_623_residues
MNQSFWRPLFAILLFMLVFHLTNIFFAQQGAQVAQISYSRLRAELAQDNIKKITLKGTAVTGEFRGKTRVSALVQGKEQQ
REFTGFSSVLPTIDDQTLVPELMARKVEVSALSTETPLLLNALIYVAPWVILIAIWWVGMRSMRSQGPSGMMGGFSRSGA
KAYLAGDKMAVSFKDVAGMEDSKQELKEVVDYLRNPKQFARIGGKVPKGVLLVGPPGTGKTLLARAVAGEAGVAFFSISA
SQFIEMFVGVGASRVRDLFTNAKKAAPSIVFIDELDAVGRSRGAGFGGGHDEREQTLNQLLSEMDGFDQHEEVIVLAATN
RPDVLDPALLRPGRFDRHVVIERPDWRDREKILQVHVRKITMNGRIDLGVIARGTPGMTGADLESLVNEAAILASRENAA
AVTMEHLEKAKDKILMGSERRMIISLEEKRITAYHEAGHTLVARLLPGTDPIHKVTIIPHGMALGVTQQLPEDDRYHYPQ
SYLENRLVVAMGGRVAERLAFGEVSSGAQGDLKQVTSLAEKMVCQWGMSEKVGGMTFSRGEEHPFLGMKLAEEKTFSEAM
AWRIDQEIAAFITRAEQRAGDLLSANRERLDLLAQALQDEETLDGSRVDEIIGSLNTAQAPPP

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family

Homologues:

Organism=Homo sapiens, GI300192933, Length=503, Percent_Identity=45.1292246520875, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI7657689, Length=445, Percent_Identity=47.8651685393258, Blast_Score=399, Evalue=1e-111,
Organism=Homo sapiens, GI21327685, Length=445, Percent_Identity=47.8651685393258, Blast_Score=399, Evalue=1e-111,
Organism=Homo sapiens, GI4507173, Length=514, Percent_Identity=41.8287937743191, Blast_Score=378, Evalue=1e-105,
Organism=Homo sapiens, GI24430151, Length=245, Percent_Identity=41.2244897959184, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI24497435, Length=255, Percent_Identity=42.7450980392157, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI195539395, Length=249, Percent_Identity=42.1686746987952, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI21361144, Length=249, Percent_Identity=41.7670682730924, Blast_Score=199, Evalue=7e-51,
Organism=Homo sapiens, GI4506209, Length=250, Percent_Identity=40, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI89064750, Length=254, Percent_Identity=40.5511811023622, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI5729991, Length=254, Percent_Identity=40.5511811023622, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI24430155, Length=254, Percent_Identity=40.5511811023622, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI6005942, Length=225, Percent_Identity=42.2222222222222, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI157671927, Length=257, Percent_Identity=39.2996108949416, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI45643125, Length=261, Percent_Identity=39.463601532567, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI45643123, Length=261, Percent_Identity=39.463601532567, Blast_Score=183, Evalue=5e-46,
Organism=Homo sapiens, GI40806173, Length=193, Percent_Identity=50.259067357513, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI229577436, Length=267, Percent_Identity=38.2022471910112, Blast_Score=169, Evalue=9e-42,
Organism=Homo sapiens, GI194018488, Length=275, Percent_Identity=38.1818181818182, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI153792536, Length=236, Percent_Identity=38.9830508474576, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI4505725, Length=220, Percent_Identity=38.1818181818182, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI24497618, Length=295, Percent_Identity=34.9152542372881, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI226371754, Length=235, Percent_Identity=37.0212765957447, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI31377644, Length=243, Percent_Identity=35.8024691358025, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI5901990, Length=246, Percent_Identity=36.5853658536585, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI14149767, Length=286, Percent_Identity=33.2167832167832, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI62177112, Length=286, Percent_Identity=33.2167832167832, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI11875211, Length=234, Percent_Identity=39.3162393162393, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI40806170, Length=234, Percent_Identity=39.3162393162393, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI310125282, Length=251, Percent_Identity=34.6613545816733, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI156564401, Length=332, Percent_Identity=31.0240963855422, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI310125280, Length=251, Percent_Identity=34.6613545816733, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI31742536, Length=226, Percent_Identity=34.5132743362832, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI112789543, Length=226, Percent_Identity=34.5132743362832, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI7019569, Length=248, Percent_Identity=34.2741935483871, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI17865802, Length=250, Percent_Identity=36, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI64084766, Length=228, Percent_Identity=27.1929824561404, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI116292174, Length=227, Percent_Identity=30.3964757709251, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4757852, Length=154, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI119964730, Length=154, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1789568, Length=608, Percent_Identity=48.6842105263158, Blast_Score=557, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI17554264, Length=448, Percent_Identity=47.9910714285714, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71994521, Length=454, Percent_Identity=46.0352422907489, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI115534323, Length=457, Percent_Identity=45.0765864332604, Blast_Score=358, Evalue=4e-99,
Organism=Caenorhabditis elegans, GI17554786, Length=255, Percent_Identity=43.921568627451, Blast_Score=218, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI25144281, Length=255, Percent_Identity=43.5294117647059, Blast_Score=212, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI25144278, Length=255, Percent_Identity=43.5294117647059, Blast_Score=212, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17563250, Length=245, Percent_Identity=42.8571428571429, Blast_Score=209, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI71987364, Length=260, Percent_Identity=42.3076923076923, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI71987372, Length=260, Percent_Identity=42.3076923076923, Blast_Score=206, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17563248, Length=252, Percent_Identity=40.8730158730159, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17532375, Length=229, Percent_Identity=39.7379912663755, Blast_Score=198, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17508701, Length=249, Percent_Identity=40.9638554216867, Blast_Score=198, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17505546, Length=249, Percent_Identity=39.7590361445783, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17508053, Length=257, Percent_Identity=39.6887159533074, Blast_Score=184, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI17531535, Length=230, Percent_Identity=40.8695652173913, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17554784, Length=250, Percent_Identity=39.6, Blast_Score=181, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17537217, Length=264, Percent_Identity=37.8787878787879, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI193206114, Length=288, Percent_Identity=37.8472222222222, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI133931034, Length=288, Percent_Identity=37.8472222222222, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI193206116, Length=288, Percent_Identity=37.8472222222222, Blast_Score=155, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI25153574, Length=230, Percent_Identity=36.9565217391304, Blast_Score=150, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI193209502, Length=229, Percent_Identity=37.117903930131, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17562804, Length=274, Percent_Identity=33.9416058394161, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25146157, Length=237, Percent_Identity=39.2405063291139, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17570397, Length=168, Percent_Identity=46.4285714285714, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32566590, Length=168, Percent_Identity=46.4285714285714, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17541224, Length=298, Percent_Identity=31.8791946308725, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17541226, Length=298, Percent_Identity=31.8791946308725, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI133901662, Length=212, Percent_Identity=35.8490566037736, Blast_Score=128, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI133901658, Length=212, Percent_Identity=35.8490566037736, Blast_Score=128, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI86561515, Length=247, Percent_Identity=34.412955465587, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17560432, Length=228, Percent_Identity=38.5964912280702, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32563584, Length=228, Percent_Identity=40.3508771929825, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17508421, Length=228, Percent_Identity=40.3508771929825, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71990294, Length=198, Percent_Identity=30.3030303030303, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320854, Length=517, Percent_Identity=43.3268858800774, Blast_Score=430, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6323736, Length=499, Percent_Identity=44.8897795591182, Blast_Score=425, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6325281, Length=448, Percent_Identity=46.6517857142857, Blast_Score=409, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6320197, Length=245, Percent_Identity=41.6326530612245, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6321390, Length=245, Percent_Identity=41.2244897959184, Blast_Score=205, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6322704, Length=255, Percent_Identity=41.5686274509804, Blast_Score=204, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6320077, Length=240, Percent_Identity=42.5, Blast_Score=204, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6324691, Length=251, Percent_Identity=42.6294820717131, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6324833, Length=245, Percent_Identity=41.2244897959184, Blast_Score=196, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6320602, Length=249, Percent_Identity=40.5622489959839, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6323429, Length=262, Percent_Identity=39.3129770992366, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322994, Length=229, Percent_Identity=41.0480349344978, Blast_Score=160, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6321709, Length=262, Percent_Identity=37.7862595419847, Blast_Score=159, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6324000, Length=275, Percent_Identity=34.9090909090909, Blast_Score=158, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6322651, Length=257, Percent_Identity=34.2412451361868, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6321465, Length=249, Percent_Identity=32.5301204819277, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6325431, Length=262, Percent_Identity=33.969465648855, Blast_Score=130, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6325183, Length=239, Percent_Identity=37.6569037656904, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6319554, Length=216, Percent_Identity=35.1851851851852, Blast_Score=127, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6320887, Length=270, Percent_Identity=36.2962962962963, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320583, Length=159, Percent_Identity=32.7044025157233, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24658770, Length=458, Percent_Identity=49.3449781659389, Blast_Score=408, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24665814, Length=453, Percent_Identity=45.4746136865342, Blast_Score=406, Evalue=1e-113,
Organism=Drosophila melanogaster, GI28574878, Length=453, Percent_Identity=45.4746136865342, Blast_Score=405, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24639391, Length=461, Percent_Identity=44.2516268980477, Blast_Score=383, Evalue=1e-106,
Organism=Drosophila melanogaster, GI19920408, Length=256, Percent_Identity=42.578125, Blast_Score=208, Evalue=9e-54,
Organism=Drosophila melanogaster, GI24651451, Length=255, Percent_Identity=43.1372549019608, Blast_Score=205, Evalue=8e-53,
Organism=Drosophila melanogaster, GI24649446, Length=245, Percent_Identity=41.2244897959184, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI161076488, Length=244, Percent_Identity=39.7540983606557, Blast_Score=203, Evalue=4e-52,
Organism=Drosophila melanogaster, GI17137560, Length=244, Percent_Identity=39.7540983606557, Blast_Score=202, Evalue=4e-52,
Organism=Drosophila melanogaster, GI161076486, Length=244, Percent_Identity=39.7540983606557, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=42.0408163265306, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI17137738, Length=250, Percent_Identity=40.8, Blast_Score=199, Evalue=5e-51,
Organism=Drosophila melanogaster, GI17738151, Length=251, Percent_Identity=41.0358565737052, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI45554047, Length=165, Percent_Identity=56.969696969697, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24663015, Length=249, Percent_Identity=40.1606425702811, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI281361487, Length=244, Percent_Identity=39.7540983606557, Blast_Score=189, Evalue=6e-48,
Organism=Drosophila melanogaster, GI18860063, Length=244, Percent_Identity=40.5737704918033, Blast_Score=189, Evalue=7e-48,
Organism=Drosophila melanogaster, GI281365776, Length=236, Percent_Identity=40.6779661016949, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24660075, Length=236, Percent_Identity=40.6779661016949, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI45552965, Length=236, Percent_Identity=40.6779661016949, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24652279, Length=206, Percent_Identity=41.2621359223301, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19921202, Length=227, Percent_Identity=37.8854625550661, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24656820, Length=277, Percent_Identity=36.8231046931408, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24656825, Length=277, Percent_Identity=36.8231046931408, Blast_Score=166, Evalue=4e-41,
Organism=Drosophila melanogaster, GI281363136, Length=234, Percent_Identity=38.8888888888889, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI78707192, Length=234, Percent_Identity=38.8888888888889, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24644145, Length=251, Percent_Identity=36.2549800796813, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21355121, Length=277, Percent_Identity=33.5740072202166, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360144, Length=248, Percent_Identity=35.8870967741936, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281360140, Length=248, Percent_Identity=35.8870967741936, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281360136, Length=248, Percent_Identity=35.8870967741936, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24644411, Length=248, Percent_Identity=35.8870967741936, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281360146, Length=248, Percent_Identity=35.8870967741936, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281360142, Length=248, Percent_Identity=35.8870967741936, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281360138, Length=248, Percent_Identity=35.8870967741936, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21357333, Length=248, Percent_Identity=35.8870967741936, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI20129529, Length=250, Percent_Identity=36.8, Blast_Score=134, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24581396, Length=233, Percent_Identity=36.9098712446352, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI17864540, Length=214, Percent_Identity=37.8504672897196, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28571849, Length=235, Percent_Identity=39.5744680851064, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI28571847, Length=235, Percent_Identity=39.5744680851064, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI18859657, Length=229, Percent_Identity=36.6812227074236, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI28573010, Length=256, Percent_Identity=33.984375, Blast_Score=126, Evalue=6e-29,
Organism=Drosophila melanogaster, GI20129423, Length=240, Percent_Identity=32.5, Blast_Score=122, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24639486, Length=211, Percent_Identity=32.7014218009479, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSH_PELPD (A1AT11)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902539.1
- ProteinModelPortal:   A1AT11
- STRING:   A1AT11
- MEROPS:   M41.001
- GeneID:   4573937
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2884
- eggNOG:   COG0465
- HOGENOM:   HBG724153
- OMA:   VCQWGMS
- PhylomeDB:   A1AT11
- ProtClustDB:   CLSK828230
- GO:   GO:0006508
- HAMAP:   MF_01458
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR000642
- SMART:   SM00382
- TIGRFAMs:   TIGR01241

Pfam domain/function: PF00004 AAA; PF01434 Peptidase_M41

EC number: 3.4.24.-

Molecular weight: Translated: 68436; Mature: 68436

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS00674 AAA

Important sites: ACT_SITE 436-436

Signals:

None

Transmembrane regions:

HASH(0x268f4518)-; HASH(0x413ce49c)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSFWRPLFAILLFMLVFHLTNIFFAQQGAQVAQISYSRLRAELAQDNIKKITLKGTAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECEEE
TGEFRGKTRVSALVQGKEQQREFTGFSSVLPTIDDQTLVPELMARKVEVSALSTETPLLL
ECCCCCCHHHHHHHHCHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHH
NALIYVAPWVILIAIWWVGMRSMRSQGPSGMMGGFSRSGAKAYLAGDKMAVSFKDVAGME
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEHHHHCCCC
DSKQELKEVVDYLRNPKQFARIGGKVPKGVLLVGPPGTGKTLLARAVAGEAGVAFFSISA
HHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCEEEEECCH
SQFIEMFVGVGASRVRDLFTNAKKAAPSIVFIDELDAVGRSRGAGFGGGHDEREQTLNQL
HHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHCCCCCCCCCCCHHHHHHHHHH
LSEMDGFDQHEEVIVLAATNRPDVLDPALLRPGRFDRHVVIERPDWRDREKILQVHVRKI
HHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHE
TMNGRIDLGVIARGTPGMTGADLESLVNEAAILASRENAAAVTMEHLEKAKDKILMGSER
EECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCC
RMIISLEEKRITAYHEAGHTLVARLLPGTDPIHKVTIIPHGMALGVTQQLPEDDRYHYPQ
EEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEECCHHHCCCCCCCCCCH
SYLENRLVVAMGGRVAERLAFGEVSSGAQGDLKQVTSLAEKMVCQWGMSEKVGGMTFSRG
HHHCCEEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
EEHPFLGMKLAEEKTFSEAMAWRIDQEIAAFITRAEQRAGDLLSANRERLDLLAQALQDE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCH
ETLDGSRVDEIIGSLNTAQAPPP
HCCCCHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure
MNQSFWRPLFAILLFMLVFHLTNIFFAQQGAQVAQISYSRLRAELAQDNIKKITLKGTAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECEEE
TGEFRGKTRVSALVQGKEQQREFTGFSSVLPTIDDQTLVPELMARKVEVSALSTETPLLL
ECCCCCCHHHHHHHHCHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHH
NALIYVAPWVILIAIWWVGMRSMRSQGPSGMMGGFSRSGAKAYLAGDKMAVSFKDVAGME
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEHHHHCCCC
DSKQELKEVVDYLRNPKQFARIGGKVPKGVLLVGPPGTGKTLLARAVAGEAGVAFFSISA
HHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCEEEEECCH
SQFIEMFVGVGASRVRDLFTNAKKAAPSIVFIDELDAVGRSRGAGFGGGHDEREQTLNQL
HHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHCCCCCCCCCCCHHHHHHHHHH
LSEMDGFDQHEEVIVLAATNRPDVLDPALLRPGRFDRHVVIERPDWRDREKILQVHVRKI
HHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHE
TMNGRIDLGVIARGTPGMTGADLESLVNEAAILASRENAAAVTMEHLEKAKDKILMGSER
EECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCC
RMIISLEEKRITAYHEAGHTLVARLLPGTDPIHKVTIIPHGMALGVTQQLPEDDRYHYPQ
EEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEECCHHHCCCCCCCCCCH
SYLENRLVVAMGGRVAERLAFGEVSSGAQGDLKQVTSLAEKMVCQWGMSEKVGGMTFSRG
HHHCCEEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
EEHPFLGMKLAEEKTFSEAMAWRIDQEIAAFITRAEQRAGDLLSANRERLDLLAQALQDE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCH
ETLDGSRVDEIIGSLNTAQAPPP
HCCCCHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA