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The map label for this gene is pilH [H]

Identifier: 118581219

GI number: 118581219

Start: 3081585

End: 3082409

Strand: Reverse

Name: pilH [H]

Synonym: Ppro_2813

Alternate gene names: 118581219

Gene position: 3082409-3081585 (Counterclockwise)

Preceding gene: 118581223

Following gene: 118581210

Centisome position: 76.91

GC content: 52.36

Gene sequence:

>825_bases
ATGAAACAGTGGAAAAAACTTGGTCATATCCTGATCGAAGAGCAGATACTGACTCCTGTTGCCGTGGCGAGGCTGCTCGC
CATCGCAAAACGGCACAATACGCGATTCGGATGGACTCTCGAGGATTTGGGACTTGTTACGGGTGATGAACTGGCCAAGG
CTCTTGCGCGCCAGTTCGAACTGAGACGGGTCACCAATCTGGTGAACGGCTCCTACAGTCAGGAGCTGCTGAACACATTT
ACCGTCGAGTTTGTGCTCGAGCAGGTGGTTTTCCCCCTCAAGCTCGAAGACAAGGTGCTGGTTGTGGCGGTTGCCGACCC
AACCGACTTGAAGACACTGCACAATTTCGGAGCGAATCATGGTGTGCAGATCATGCCGTGCGTTGCAAGCCGCAGGGAGA
TCCATGAAGCTATCTGCACATTCTATCTTGGAAAAAACATTCAGGAGTCCAAACAGACAACGGTTCTCGTTGTGGACGAT
GACGTGCTTATCCAGACAATCCTGAGAGATATGCTCAACAGTCATGGATATCGCGTCGTAATCGCCAAGGATGGGATCGA
AGGCTTCAGGGAGACGATTGCCTGCAGGCCTCAGATCATTCTTACCGACAAGGTGATGCCGAAGCTGGATGGGTTCGCAC
TGCTCAGTTCTCTCAAGGCAATCCCCGAGTTCAGAGCGATTCCGGTCATTCTGATCAGCGACAAGATGACCGATGATGAC
GAAGCGCGGGTTTTCAGGATGGGGTTTTTCGATTACATCCCCAAGCCGATCAAGGAAATTACGCTCATATCGCGGATCGA
GCGGGCTCTGGGGCGTTACGAATAG

Upstream 100 bases:

>100_bases
CTCATCAAGGCATCCCCTGCTGGTTTTTATCAGCAATTCGGTTCATTCTATCTTTAAGTCGATCTCAGCTTGCATGGCTC
TGGACACGCGGAGCATTTCA

Downstream 100 bases:

>100_bases
GCAAGGGGGCTGAGCGTGGAACCGGACACGGCCGTCCCGTCTCCTGGTCATCCCGGGCAGTGCCGCCCGTCAAGTATGGA
GCGCACCATCTGAGACAGCT

Product: response regulator receiver protein

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKQWKKLGHILIEEQILTPVAVARLLAIAKRHNTRFGWTLEDLGLVTGDELAKALARQFELRRVTNLVNGSYSQELLNTF
TVEFVLEQVVFPLKLEDKVLVVAVADPTDLKTLHNFGANHGVQIMPCVASRREIHEAICTFYLGKNIQESKQTTVLVVDD
DVLIQTILRDMLNSHGYRVVIAKDGIEGFRETIACRPQIILTDKVMPKLDGFALLSSLKAIPEFRAIPVILISDKMTDDD
EARVFRMGFFDYIPKPIKEITLISRIERALGRYE

Sequences:

>Translated_274_residues
MKQWKKLGHILIEEQILTPVAVARLLAIAKRHNTRFGWTLEDLGLVTGDELAKALARQFELRRVTNLVNGSYSQELLNTF
TVEFVLEQVVFPLKLEDKVLVVAVADPTDLKTLHNFGANHGVQIMPCVASRREIHEAICTFYLGKNIQESKQTTVLVVDD
DVLIQTILRDMLNSHGYRVVIAKDGIEGFRETIACRPQIILTDKVMPKLDGFALLSSLKAIPEFRAIPVILISDKMTDDD
EARVFRMGFFDYIPKPIKEITLISRIERALGRYE
>Mature_274_residues
MKQWKKLGHILIEEQILTPVAVARLLAIAKRHNTRFGWTLEDLGLVTGDELAKALARQFELRRVTNLVNGSYSQELLNTF
TVEFVLEQVVFPLKLEDKVLVVAVADPTDLKTLHNFGANHGVQIMPCVASRREIHEAICTFYLGKNIQESKQTTVLVVDD
DVLIQTILRDMLNSHGYRVVIAKDGIEGFRETIACRPQIILTDKVMPKLDGFALLSSLKAIPEFRAIPVILISDKMTDDD
EARVFRMGFFDYIPKPIKEITLISRIERALGRYE

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=31.6666666666667, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=31.6239316239316, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 31086; Mature: 31086

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQWKKLGHILIEEQILTPVAVARLLAIAKRHNTRFGWTLEDLGLVTGDELAKALARQFE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHH
LRRVTNLVNGSYSQELLNTFTVEFVLEQVVFPLKLEDKVLVVAVADPTDLKTLHNFGANH
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEECCCHHHHHHHHCCCCC
GVQIMPCVASRREIHEAICTFYLGKNIQESKQTTVLVVDDDVLIQTILRDMLNSHGYRVV
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEE
IAKDGIEGFRETIACRPQIILTDKVMPKLDGFALLSSLKAIPEFRAIPVILISDKMTDDD
EECCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHCCEEEEEECCCCCCC
EARVFRMGFFDYIPKPIKEITLISRIERALGRYE
HHHEEEHHHHHHCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKQWKKLGHILIEEQILTPVAVARLLAIAKRHNTRFGWTLEDLGLVTGDELAKALARQFE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHH
LRRVTNLVNGSYSQELLNTFTVEFVLEQVVFPLKLEDKVLVVAVADPTDLKTLHNFGANH
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEECCCHHHHHHHHCCCCC
GVQIMPCVASRREIHEAICTFYLGKNIQESKQTTVLVVDDDVLIQTILRDMLNSHGYRVV
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEE
IAKDGIEGFRETIACRPQIILTDKVMPKLDGFALLSSLKAIPEFRAIPVILISDKMTDDD
EECCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHCCEEEEEECCCCCCC
EARVFRMGFFDYIPKPIKEITLISRIERALGRYE
HHHEEEHHHHHHCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]