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The map label for this gene is fdhA [H]

Identifier: 118581197

GI number: 118581197

Start: 3052305

End: 3054311

Strand: Reverse

Name: fdhA [H]

Synonym: Ppro_2790

Alternate gene names: 118581197

Gene position: 3054311-3052305 (Counterclockwise)

Preceding gene: 118581198

Following gene: 118581196

Centisome position: 76.21

GC content: 62.28

Gene sequence:

>2007_bases
ATGGCTCAAAGTCTAACCACCTGCACCTTTTGCGGCGTAGGGTGTGGTCTCTATCTTGAGACTACTCCTGAACGCATTGC
TGGCGTCTACCCCAGCGTATCGCACCCCGCAAACAAGGGCAAAATCTGCATCCGCGGCTGGCACGTTCATGAAGTTGCCA
GCTCCCCCGACCGCCTGAAGGCACCGCTTCTCAGGAAGAACGGCCAGCTCGAAGAAGTGACGTGGCAGGAGGCGTATGAG
TTCATCGCCTCACGTCTGAAGGAGATCAAGGGCGCCTCCGGTCCCGACTCGATCGCCTTTCTGAACTCTCCGCGTTGCTG
CAACGAAGAGAGCTACCTTCTTCAGAAGCTTGCGCGCAGCGTCATCGGCACCAACAACGTGGACCATGGCGCCGGCGTGT
ACAGCAACAACTCGGTCAACGTCCTTCTGGACATGCTGGGTGTTGCCGCCGCCACCAACTCCATCGACGACCTGGAGCAG
AGCGACCTGATCATCGTCGACGGCGTTGACCTTGCCCGTCAGCTTCCCACCGTAGCGGGCACGGTGCTGCGCGCCAGACT
CAGCGGCGCCAAGCTGGTGGTCATCGGCGAGCGTCGTCAGCGTGTTGCCGAGAACGCCGACTGGTTTCTGCAGATCAACC
CGGGCACGGAAGCCGTTCTCTACGGCGCCATGGCCAAACTGATCGTGGACCACGGCCTGATGGACCTTGCCTTCATCAAG
GCCAACTGTTCTGACTACGATGCCTTTCTGGCCCAGGCCAAGCAGTACGACCTGATCGCCGCCGCCCAGACCTGCGGCGT
TCCTGCCGAACAGATCGAAGCCGTAGCCGTAGCCTACGCCAAATCAAAATCCTCGGCCATCCTGTACTCCACCGGCGCCG
AGACCCGTGACTCCGACTCCATCAGGGCGGCCGTCAACCTGGCGCTTCTGGCCGGCCAGATCGGCAAAGTCGGCTCTGGC
ATCTTCCCGCTGGCCGAACACAACAACCTTCAGGGCACCTGCGACATGGGCATGCTTCCCGACCGCCTTCCCGGCTACCG
TCCGCTCTCCGCGGGGAGCGAGCTTGAAAGCGTGTATGGCGCCAAGCTTCCGGCTACCCCCGGCGTAACGGCCGCAGCCG
TGCTGAAAGACCGTGCCAAGGGTAAAATCAAGGCGGTCTGGCTGGACCGTTACGACCCGGTCAACACCGCCGCCCTGGGC
AGCGCCGCCAAGGCTTTGGAAGAGTGCGAGCTGGTCATCGTCCAGCACCTGTTTTTGACTGAAACCGCCAAACTGGCCGA
CGTCGTCCTTCCCACCACCGCCTTCGGTGAAGAGACGGTCAGCTTCACCAGCACCGAGCGTCGCATCCAGCTCGCCCGCC
AGGCCGTTCCTGCGCCTCAGGGGATCACCCCTGCCTGGCAGCAGATCGCCCAGGTGGCCAAGGCACTGGGAAGTGACTGG
AACTATGCCGACGCGGCAGCGGTCATGGCCGAGATCGGCCGGGCCGTACCTTCCTACAGCGCCGCCGACTACGACAGCCT
GGGTGTTGAATTCGGCCGTCAGTGGCCCTGCACCAAGGACGCGCCCCACGGCACGCCGATCCTGTTTAGCGGCGGTTCCG
GCAGCTTCAAATTTGTACCGGTCGCCAAGCCTTCGGCTCCCGCCGCCTTAAGCACGGACTTCCCCTTCACCCTGGTACTG
GGCAACTCCAGCTACTACTGGAACCAGAACGTCCTCATCGCCCACAGCGAGATCTTAAAGCGTGAATACCGGGTAATGCT
CCTGGACTATCCGCAAGGGTTCGTCGAGATCAATGCTGACGACGCCAAGGAGATGAAGATCCGGGACAAGCAGAAGATCA
AACTCTGCGGCGGCTCCGGCTGCGCCGTAACCGTTGCCCGCGTCACCCCCGAGGTCAAGCGGGGCACGGTATTTGTACCC
TACCAGGAGCTGAGCCAGATGCAGGCGATGCGCGGTGCGGATGACGCCCGGTTCCTGGCTGTTCGTGTAGAAACGGAGGT
CGCATGA

Upstream 100 bases:

>100_bases
TAAGAGTAAAAATCCCACCATATCCGTAACTTATGGAATTCCTCGGTGTATTCCGACTTTCCCACCCGGCGACAGGATTG
GGTTGAAACGGGAGTGACGC

Downstream 100 bases:

>100_bases
AAGCACGTATCTTGAGCCGCGCCGATGTGCTGAACGTAATCGATCAGCTGCGCGGACAGGGCTTTGAGGTCCTGGCCCCC
TTCCTCGGTCGCGGTAGCGA

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 668; Mature: 667

Protein sequence:

>668_residues
MAQSLTTCTFCGVGCGLYLETTPERIAGVYPSVSHPANKGKICIRGWHVHEVASSPDRLKAPLLRKNGQLEEVTWQEAYE
FIASRLKEIKGASGPDSIAFLNSPRCCNEESYLLQKLARSVIGTNNVDHGAGVYSNNSVNVLLDMLGVAAATNSIDDLEQ
SDLIIVDGVDLARQLPTVAGTVLRARLSGAKLVVIGERRQRVAENADWFLQINPGTEAVLYGAMAKLIVDHGLMDLAFIK
ANCSDYDAFLAQAKQYDLIAAAQTCGVPAEQIEAVAVAYAKSKSSAILYSTGAETRDSDSIRAAVNLALLAGQIGKVGSG
IFPLAEHNNLQGTCDMGMLPDRLPGYRPLSAGSELESVYGAKLPATPGVTAAAVLKDRAKGKIKAVWLDRYDPVNTAALG
SAAKALEECELVIVQHLFLTETAKLADVVLPTTAFGEETVSFTSTERRIQLARQAVPAPQGITPAWQQIAQVAKALGSDW
NYADAAAVMAEIGRAVPSYSAADYDSLGVEFGRQWPCTKDAPHGTPILFSGGSGSFKFVPVAKPSAPAALSTDFPFTLVL
GNSSYYWNQNVLIAHSEILKREYRVMLLDYPQGFVEINADDAKEMKIRDKQKIKLCGGSGCAVTVARVTPEVKRGTVFVP
YQELSQMQAMRGADDARFLAVRVETEVA

Sequences:

>Translated_668_residues
MAQSLTTCTFCGVGCGLYLETTPERIAGVYPSVSHPANKGKICIRGWHVHEVASSPDRLKAPLLRKNGQLEEVTWQEAYE
FIASRLKEIKGASGPDSIAFLNSPRCCNEESYLLQKLARSVIGTNNVDHGAGVYSNNSVNVLLDMLGVAAATNSIDDLEQ
SDLIIVDGVDLARQLPTVAGTVLRARLSGAKLVVIGERRQRVAENADWFLQINPGTEAVLYGAMAKLIVDHGLMDLAFIK
ANCSDYDAFLAQAKQYDLIAAAQTCGVPAEQIEAVAVAYAKSKSSAILYSTGAETRDSDSIRAAVNLALLAGQIGKVGSG
IFPLAEHNNLQGTCDMGMLPDRLPGYRPLSAGSELESVYGAKLPATPGVTAAAVLKDRAKGKIKAVWLDRYDPVNTAALG
SAAKALEECELVIVQHLFLTETAKLADVVLPTTAFGEETVSFTSTERRIQLARQAVPAPQGITPAWQQIAQVAKALGSDW
NYADAAAVMAEIGRAVPSYSAADYDSLGVEFGRQWPCTKDAPHGTPILFSGGSGSFKFVPVAKPSAPAALSTDFPFTLVL
GNSSYYWNQNVLIAHSEILKREYRVMLLDYPQGFVEINADDAKEMKIRDKQKIKLCGGSGCAVTVARVTPEVKRGTVFVP
YQELSQMQAMRGADDARFLAVRVETEVA
>Mature_667_residues
AQSLTTCTFCGVGCGLYLETTPERIAGVYPSVSHPANKGKICIRGWHVHEVASSPDRLKAPLLRKNGQLEEVTWQEAYEF
IASRLKEIKGASGPDSIAFLNSPRCCNEESYLLQKLARSVIGTNNVDHGAGVYSNNSVNVLLDMLGVAAATNSIDDLEQS
DLIIVDGVDLARQLPTVAGTVLRARLSGAKLVVIGERRQRVAENADWFLQINPGTEAVLYGAMAKLIVDHGLMDLAFIKA
NCSDYDAFLAQAKQYDLIAAAQTCGVPAEQIEAVAVAYAKSKSSAILYSTGAETRDSDSIRAAVNLALLAGQIGKVGSGI
FPLAEHNNLQGTCDMGMLPDRLPGYRPLSAGSELESVYGAKLPATPGVTAAAVLKDRAKGKIKAVWLDRYDPVNTAALGS
AAKALEECELVIVQHLFLTETAKLADVVLPTTAFGEETVSFTSTERRIQLARQAVPAPQGITPAWQQIAQVAKALGSDWN
YADAAAVMAEIGRAVPSYSAADYDSLGVEFGRQWPCTKDAPHGTPILFSGGSGSFKFVPVAKPSAPAALSTDFPFTLVLG
NSSYYWNQNVLIAHSEILKREYRVMLLDYPQGFVEINADDAKEMKIRDKQKIKLCGGSGCAVTVARVTPEVKRGTVFVPY
QELSQMQAMRGADDARFLAVRVETEVA

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=693, Percent_Identity=31.3131313131313, Blast_Score=335, Evalue=8e-93,
Organism=Escherichia coli, GI1788534, Length=771, Percent_Identity=22.568093385214, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI3868720, Length=444, Percent_Identity=27.9279279279279, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI3868719, Length=441, Percent_Identity=24.4897959183673, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI171474008, Length=534, Percent_Identity=24.9063670411985, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1787778, Length=373, Percent_Identity=26.2734584450402, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1787870, Length=473, Percent_Identity=24.5243128964059, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 71666; Mature: 71535

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1 ; PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSLTTCTFCGVGCGLYLETTPERIAGVYPSVSHPANKGKICIRGWHVHEVASSPDRLK
CCCCCCCHHHHHCCCCEEEECCHHHHHCCCCCCCCCCCCCCEEEEEEEEHHHCCCCHHHH
APLLRKNGQLEEVTWQEAYEFIASRLKEIKGASGPDSIAFLNSPRCCNEESYLLQKLARS
CCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
VIGTNNVDHGAGVYSNNSVNVLLDMLGVAAATNSIDDLEQSDLIIVDGVDLARQLPTVAG
HHCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCHHCCCCCCEEEEECHHHHHHHHHHHH
TVLRARLSGAKLVVIGERRQRVAENADWFLQINPGTEAVLYGAMAKLIVDHGLMDLAFIK
HHHHHHCCCCEEEEECCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEE
ANCSDYDAFLAQAKQYDLIAAAQTCGVPAEQIEAVAVAYAKSKSSAILYSTGAETRDSDS
CCCCHHHHHHHHHHHHHHEEHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCH
IRAAVNLALLAGQIGKVGSGIFPLAEHNNLQGTCDMGMLPDRLPGYRPLSAGSELESVYG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHC
AKLPATPGVTAAAVLKDRAKGKIKAVWLDRYDPVNTAALGSAAKALEECELVIVQHLFLT
CCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ETAKLADVVLPTTAFGEETVSFTSTERRIQLARQAVPAPQGITPAWQQIAQVAKALGSDW
HHHHHHHHEECCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
NYADAAAVMAEIGRAVPSYSAADYDSLGVEFGRQWPCTKDAPHGTPILFSGGSGSFKFVP
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEEEE
VAKPSAPAALSTDFPFTLVLGNSSYYWNQNVLIAHSEILKREYRVMLLDYPQGFVEINAD
ECCCCCCCEEECCCCEEEEECCCEEEECCCEEEEHHHHHHHCEEEEEEECCCCEEEECCC
DAKEMKIRDKQKIKLCGGSGCAVTVARVTPEVKRGTVFVPYQELSQMQAMRGADDARFLA
CCHHHHCCCCCEEEEECCCCCEEEEEECCCCHHCCEEEECHHHHHHHHHHHCCCCCEEEE
VRVETEVA
EEEEECCC
>Mature Secondary Structure 
AQSLTTCTFCGVGCGLYLETTPERIAGVYPSVSHPANKGKICIRGWHVHEVASSPDRLK
CCCCCCHHHHHCCCCEEEECCHHHHHCCCCCCCCCCCCCCEEEEEEEEHHHCCCCHHHH
APLLRKNGQLEEVTWQEAYEFIASRLKEIKGASGPDSIAFLNSPRCCNEESYLLQKLARS
CCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
VIGTNNVDHGAGVYSNNSVNVLLDMLGVAAATNSIDDLEQSDLIIVDGVDLARQLPTVAG
HHCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCHHCCCCCCEEEEECHHHHHHHHHHHH
TVLRARLSGAKLVVIGERRQRVAENADWFLQINPGTEAVLYGAMAKLIVDHGLMDLAFIK
HHHHHHCCCCEEEEECCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEE
ANCSDYDAFLAQAKQYDLIAAAQTCGVPAEQIEAVAVAYAKSKSSAILYSTGAETRDSDS
CCCCHHHHHHHHHHHHHHEEHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCH
IRAAVNLALLAGQIGKVGSGIFPLAEHNNLQGTCDMGMLPDRLPGYRPLSAGSELESVYG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHC
AKLPATPGVTAAAVLKDRAKGKIKAVWLDRYDPVNTAALGSAAKALEECELVIVQHLFLT
CCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ETAKLADVVLPTTAFGEETVSFTSTERRIQLARQAVPAPQGITPAWQQIAQVAKALGSDW
HHHHHHHHEECCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
NYADAAAVMAEIGRAVPSYSAADYDSLGVEFGRQWPCTKDAPHGTPILFSGGSGSFKFVP
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEEEE
VAKPSAPAALSTDFPFTLVLGNSSYYWNQNVLIAHSEILKREYRVMLLDYPQGFVEINAD
ECCCCCCCEEECCCCEEEEECCCEEEECCCEEEEHHHHHHHCEEEEEEECCCCEEEECCC
DAKEMKIRDKQKIKLCGGSGCAVTVARVTPEVKRGTVFVPYQELSQMQAMRGADDARFLA
CCHHHHCCCCCEEEEECCCCCEEEEEECCCCHHCCEEEECHHHHHHHHHHHCCCCCEEEE
VRVETEVA
EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]