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The map label for this gene is nreC [H]

Identifier: 118581123

GI number: 118581123

Start: 2956560

End: 2957186

Strand: Reverse

Name: nreC [H]

Synonym: Ppro_2713

Alternate gene names: 118581123

Gene position: 2957186-2956560 (Counterclockwise)

Preceding gene: 118581124

Following gene: 118581122

Centisome position: 73.78

GC content: 60.77

Gene sequence:

>627_bases
ATGACGGTCAGGATACTGATTGCCGATGACCATGCCATTGTTCGCGAGGGGCTCACCATGATACTGGAATCCTCCGGCAT
GATTGTTGCCGGGGAGGCTCGGGACGGTCGCGATGCCCTGTCACAGACCGAAGTGCTCAGGCCCGATGTGGTTGTCATGG
ATATTGCCATGCCGGAGCTGAACGGCATCGATGCGACCCGCATGATTCATGGGCGTTTGCCGGAGGTCAAGGTGATCGTG
CTCTCCATGCATAACACTCGTGAGCATGTTTTTCGCGCCATGCAGGCCGGTGCGCGCGCTTACCTGCTCAAGGAGTCCGC
CGGTTCCGGGCTCGTGGACGCGGTTCGCGCCGTGATCAGGGGGGAGTGCTATTTCGGTGAGGGGGTTGACGCTCCCCAGG
CGGTGGCCGGTTTCAAGAGCCCCTTGGACAGCCTCAGTCTGCGGGAACGGGAGGTCATTCAACTGGTGGTGGAGGGGAGA
ACCAGCGCGGAAATCGCCGAACTGCTCTCTCTGTCCCCCAAGAGCATCGAGACCTACCGCAGTCGCTTGATGGTGAAGCT
GGGGGTGGGCAATATCCCGGCTCTGGTCAAATTCGCGCTCCAGCATGGCATCACGCCGACCCAGTAA

Upstream 100 bases:

>100_bases
GCGGGAGCGCGCCGAGTTGTTCGGCGGGGTCTTTCGTGTCCATGCCCTCCCCGCCGGGGGGGTTGGCGTAACCGTGGAAA
TGCCGAAGGAGGAACCGTAG

Downstream 100 bases:

>100_bases
AAAAAACCTGATCAAACTTTCCCGACAGACCGCTGCGTTCTGTTCTGCTATGTATGTCCCATGTTCAGAAAAAGCGGCGG
TTCTTCATGACTGTTTTTTG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTVRILIADDHAIVREGLTMILESSGMIVAGEARDGRDALSQTEVLRPDVVVMDIAMPELNGIDATRMIHGRLPEVKVIV
LSMHNTREHVFRAMQAGARAYLLKESAGSGLVDAVRAVIRGECYFGEGVDAPQAVAGFKSPLDSLSLREREVIQLVVEGR
TSAEIAELLSLSPKSIETYRSRLMVKLGVGNIPALVKFALQHGITPTQ

Sequences:

>Translated_208_residues
MTVRILIADDHAIVREGLTMILESSGMIVAGEARDGRDALSQTEVLRPDVVVMDIAMPELNGIDATRMIHGRLPEVKVIV
LSMHNTREHVFRAMQAGARAYLLKESAGSGLVDAVRAVIRGECYFGEGVDAPQAVAGFKSPLDSLSLREREVIQLVVEGR
TSAEIAELLSLSPKSIETYRSRLMVKLGVGNIPALVKFALQHGITPTQ
>Mature_207_residues
TVRILIADDHAIVREGLTMILESSGMIVAGEARDGRDALSQTEVLRPDVVVMDIAMPELNGIDATRMIHGRLPEVKVIVL
SMHNTREHVFRAMQAGARAYLLKESAGSGLVDAVRAVIRGECYFGEGVDAPQAVAGFKSPLDSLSLREREVIQLVVEGRT
SAEIAELLSLSPKSIETYRSRLMVKLGVGNIPALVKFALQHGITPTQ

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=36.3636363636364, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1788712, Length=206, Percent_Identity=28.6407766990291, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1790102, Length=191, Percent_Identity=34.5549738219895, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=29.126213592233, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1786747, Length=199, Percent_Identity=27.1356783919598, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788546, Length=212, Percent_Identity=29.2452830188679, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=26.775956284153, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22555; Mature: 22423

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRILIADDHAIVREGLTMILESSGMIVAGEARDGRDALSQTEVLRPDVVVMDIAMPEL
CEEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCC
NGIDATRMIHGRLPEVKVIVLSMHNTREHVFRAMQAGARAYLLKESAGSGLVDAVRAVIR
CCCCHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHC
GECYFGEGVDAPQAVAGFKSPLDSLSLREREVIQLVVEGRTSAEIAELLSLSPKSIETYR
CCCEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHH
SRLMVKLGVGNIPALVKFALQHGITPTQ
HHEEEEECCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVRILIADDHAIVREGLTMILESSGMIVAGEARDGRDALSQTEVLRPDVVVMDIAMPEL
EEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCC
NGIDATRMIHGRLPEVKVIVLSMHNTREHVFRAMQAGARAYLLKESAGSGLVDAVRAVIR
CCCCHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHC
GECYFGEGVDAPQAVAGFKSPLDSLSLREREVIQLVVEGRTSAEIAELLSLSPKSIETYR
CCCEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHH
SRLMVKLGVGNIPALVKFALQHGITPTQ
HHEEEEECCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA