Click here to switch to the map view.

The map label for this gene is zraS [C]

Identifier: 118581010

GI number: 118581010

Start: 2820309

End: 2822294

Strand: Direct

Name: zraS [C]

Synonym: Ppro_2598

Alternate gene names: 118581010

Gene position: 2820309-2822294 (Clockwise)

Preceding gene: 118581009

Following gene: 118581018

Centisome position: 70.37

GC content: 58.46

Gene sequence:

>1986_bases
ATGATATCGGTCTTTATCGTTGATGACAATGGCCAGGGCATGGAGAAGGCGCGGGCCCTGCTTCGTGACCACGGCTATTC
GGTTTGCGATTCAGACCCGGAAGCGGATGACGCGATGCGCTTCCAGTTCGCCATGGACCGCGCCTGTATCCAGGTATTCT
GGCTTTTCGAGAACGGTCGCCTCGTTTATGTCAACGAAGCGGCCTGCCGCTCTCTGGGGTACGGACACGAGGAACTGGCA
GGCATGACCGTGTACGACATCTCCCCCCACTGTACTGTGGAAGAGTATGCGGCGCTCTGGCAGCAGACACGAAAGCAGGG
GGTTGATCGGTTTGAAGCAGTGCACCAGACCAGGGATGGCCGCACCTATCCGGTGGAAATCCAGTCGAACTTCGTTGAAT
TCGAGGGGTGTGAATACTGCTGCTGTTTCGTGACCGACATCAGTGAACGCAAGCGGGCCGAGGAGAAGCTCCTGCTGCAC
GAGTTCTGCATCGAGAAGGCCTCCATCGGCATTTTTTTGATATCGATGGACGGGAGGATTGCCATGGCCAACGAGTGCGC
ATGCAGGAGCCTCGGCTATTCCAGCGATGAATTATGTGCCATGACCGTCATTGACATCGATCCGGCCATTACCGTTGAAA
AGATACGTGCAATCGTAGAGCAGCTGGAAACCAACGGCTCCGTGACGCACGAAACCGTTCACCGCCACAGGGACGGCACC
ACCTTTCCGGTGGAGATAACGACCAACAACATCGAATTCCATGGAGCCACATATTCCTACTCCTTTGCCAAGGACATCAG
CGGACGGAAACAGGCCGAGGAGAAGCGGAAGCTTCTCGAAACGCAGCTTCACCAGATGCAGAAGCTGGATGCCGTGGGAC
AACTGGCCGGCGGCATAGCCCACGACTTCAACAACATCCTCACGGCCATCATAGGGTTTGCCGAGGTCATGGACATGCGC
ATGGAGCAGGGCGCCCCCCTCCGGCACCATGTCAGACAGATCCTGGCTGCGGCGGAGAGGGCCGCAGACCTCACCCAGGG
ACTGCTGGCGTTCAGTCGCAAGCAGGTGCTGCACGTCAGGTGCCTGGATCTGCGCGAGATCATCGACGGCCTCAAAAAAA
TGCTGTGCAGGCTGATACCGGAGGACATCGACTTCAGGGTAAAGACCGCGGCAACGGAGATGACCGTCATGGCGGACAGG
GGGCAGATCGAACAGGTGCTCATGAACCTGGTGACCAATGCCCGGGACGCCATGCCAGGCGGAGGAGTGCTGACAATCAA
GACCGGCACCGGCGTCATCGACGAGGAGTTTGTGAGGACAAACGGTTTCGGGGTTATGGGGAATTACGCCTTGATCAGCG
TCACGGACAATGGCTGCGGCATGAATGCGGAGACGCGGGAAAAGGTCTTCGAGCCGTTCTTTACCACCAAGAGGCGCGGC
AAGGGGACCGGCCTCGGCCTCTCCATCATCTACGGCATCGTCAAGCAGCATGATGGGTTCATCACCGTCGACAGTTCGCC
GGGACAGGGTGCGACCTTCCGCGTCTACCTCCCCCTGGCAGGCAGGGAAAAGGAGGAGACTCGCGAACACCGTCAGACGC
CCCTGCCAAAACGGGGAAACGAAACGGTTCTACTGGTGGAAGACGACGAGGTGGTGCGTGAACTAAACCGGGCCGTCCTG
GAATATGCTGGGTATACGGTGATCGAAACCATCGACGGCCGGGAGGCCCTGGAGAGGTTCAGGGAGCAGAGTCACCGGAT
GGACATCCTGGTCAGCGACATCATCATGCCCAACCTGGACGGAAAGGCGCTCTACGACGAGATCATGAAGATCCGGCCTG
ACATGAAGGTACTCTTCATCAGCGGGTATGCGGAGGACGCCCTTGACGCCAGGGGCCTGTTCGAAAGCGAGCACAACTTC
ATGCCCAAACCGGTCAAACCGTCGGAGCTCCTGAAAAGGGTGCGGGAGATCCTCGACCACCCCTGA

Upstream 100 bases:

>100_bases
CCACTGTCAGGTCAGCAGTGGATACGATATGAATACGTTCAGGGCACATGAGTATGCATGACGACAGCAGCGACCCGTGC
TCCCCCCAAGAGGTGATTGC

Downstream 100 bases:

>100_bases
CCACCGGCGACAGCGGACAGGGAGCATCCCCTGCCGGGTGCAGAAACAGGAAAGGGGATGCCCCATACAAGGCATCCCCT
TTTTTTACTCTCCCCGTCCT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MISVFIVDDNGQGMEKARALLRDHGYSVCDSDPEADDAMRFQFAMDRACIQVFWLFENGRLVYVNEAACRSLGYGHEELA
GMTVYDISPHCTVEEYAALWQQTRKQGVDRFEAVHQTRDGRTYPVEIQSNFVEFEGCEYCCCFVTDISERKRAEEKLLLH
EFCIEKASIGIFLISMDGRIAMANECACRSLGYSSDELCAMTVIDIDPAITVEKIRAIVEQLETNGSVTHETVHRHRDGT
TFPVEITTNNIEFHGATYSYSFAKDISGRKQAEEKRKLLETQLHQMQKLDAVGQLAGGIAHDFNNILTAIIGFAEVMDMR
MEQGAPLRHHVRQILAAAERAADLTQGLLAFSRKQVLHVRCLDLREIIDGLKKMLCRLIPEDIDFRVKTAATEMTVMADR
GQIEQVLMNLVTNARDAMPGGGVLTIKTGTGVIDEEFVRTNGFGVMGNYALISVTDNGCGMNAETREKVFEPFFTTKRRG
KGTGLGLSIIYGIVKQHDGFITVDSSPGQGATFRVYLPLAGREKEETREHRQTPLPKRGNETVLLVEDDEVVRELNRAVL
EYAGYTVIETIDGREALERFREQSHRMDILVSDIIMPNLDGKALYDEIMKIRPDMKVLFISGYAEDALDARGLFESEHNF
MPKPVKPSELLKRVREILDHP

Sequences:

>Translated_661_residues
MISVFIVDDNGQGMEKARALLRDHGYSVCDSDPEADDAMRFQFAMDRACIQVFWLFENGRLVYVNEAACRSLGYGHEELA
GMTVYDISPHCTVEEYAALWQQTRKQGVDRFEAVHQTRDGRTYPVEIQSNFVEFEGCEYCCCFVTDISERKRAEEKLLLH
EFCIEKASIGIFLISMDGRIAMANECACRSLGYSSDELCAMTVIDIDPAITVEKIRAIVEQLETNGSVTHETVHRHRDGT
TFPVEITTNNIEFHGATYSYSFAKDISGRKQAEEKRKLLETQLHQMQKLDAVGQLAGGIAHDFNNILTAIIGFAEVMDMR
MEQGAPLRHHVRQILAAAERAADLTQGLLAFSRKQVLHVRCLDLREIIDGLKKMLCRLIPEDIDFRVKTAATEMTVMADR
GQIEQVLMNLVTNARDAMPGGGVLTIKTGTGVIDEEFVRTNGFGVMGNYALISVTDNGCGMNAETREKVFEPFFTTKRRG
KGTGLGLSIIYGIVKQHDGFITVDSSPGQGATFRVYLPLAGREKEETREHRQTPLPKRGNETVLLVEDDEVVRELNRAVL
EYAGYTVIETIDGREALERFREQSHRMDILVSDIIMPNLDGKALYDEIMKIRPDMKVLFISGYAEDALDARGLFESEHNF
MPKPVKPSELLKRVREILDHP
>Mature_661_residues
MISVFIVDDNGQGMEKARALLRDHGYSVCDSDPEADDAMRFQFAMDRACIQVFWLFENGRLVYVNEAACRSLGYGHEELA
GMTVYDISPHCTVEEYAALWQQTRKQGVDRFEAVHQTRDGRTYPVEIQSNFVEFEGCEYCCCFVTDISERKRAEEKLLLH
EFCIEKASIGIFLISMDGRIAMANECACRSLGYSSDELCAMTVIDIDPAITVEKIRAIVEQLETNGSVTHETVHRHRDGT
TFPVEITTNNIEFHGATYSYSFAKDISGRKQAEEKRKLLETQLHQMQKLDAVGQLAGGIAHDFNNILTAIIGFAEVMDMR
MEQGAPLRHHVRQILAAAERAADLTQGLLAFSRKQVLHVRCLDLREIIDGLKKMLCRLIPEDIDFRVKTAATEMTVMADR
GQIEQVLMNLVTNARDAMPGGGVLTIKTGTGVIDEEFVRTNGFGVMGNYALISVTDNGCGMNAETREKVFEPFFTTKRRG
KGTGLGLSIIYGIVKQHDGFITVDSSPGQGATFRVYLPLAGREKEETREHRQTPLPKRGNETVLLVEDDEVVRELNRAVL
EYAGYTVIETIDGREALERFREQSHRMDILVSDIIMPNLDGKALYDEIMKIRPDMKVLFISGYAEDALDARGLFESEHNF
MPKPVKPSELLKRVREILDHP

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788549, Length=373, Percent_Identity=28.4182305630027, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI1788713, Length=237, Percent_Identity=30.8016877637131, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790300, Length=354, Percent_Identity=26.8361581920904, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=269, Percent_Identity=26.3940520446097, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994928, Length=329, Percent_Identity=25.8358662613982, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI145693157, Length=289, Percent_Identity=25.6055363321799, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790346, Length=85, Percent_Identity=38.8235294117647, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786600, Length=249, Percent_Identity=24.0963855421687, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74422; Mature: 74422

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFIVDDNGQGMEKARALLRDHGYSVCDSDPEADDAMRFQFAMDRACIQVFWLFENGR
CEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEECCE
LVYVNEAACRSLGYGHEELAGMTVYDISPHCTVEEYAALWQQTRKQGVDRFEAVHQTRDG
EEEEEHHHHHHCCCCHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RTYPVEIQSNFVEFEGCEYCCCFVTDISERKRAEEKLLLHEFCIEKASIGIFLISMDGRI
CEEEEEEECCEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCE
AMANECACRSLGYSSDELCAMTVIDIDPAITVEKIRAIVEQLETNGSVTHETVHRHRDGT
EECCHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCC
TFPVEITTNNIEFHGATYSYSFAKDISGRKQAEEKRKLLETQLHQMQKLDAVGQLAGGIA
EEEEEEEECCEEEECCEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDFNNILTAIIGFAEVMDMRMEQGAPLRHHVRQILAAAERAADLTQGLLAFSRKQVLHVR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CLDLREIIDGLKKMLCRLIPEDIDFRVKTAATEMTVMADRGQIEQVLMNLVTNARDAMPG
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHCCCC
GGVLTIKTGTGVIDEEFVRTNGFGVMGNYALISVTDNGCGMNAETREKVFEPFFTTKRRG
CCEEEEECCCCCCCHHHHHCCCCEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
KGTGLGLSIIYGIVKQHDGFITVDSSPGQGATFRVYLPLAGREKEETREHRQTPLPKRGN
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCC
ETVLLVEDDEVVRELNRAVLEYAGYTVIETIDGREALERFREQSHRMDILVSDIIMPNLD
CEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GKALYDEIMKIRPDMKVLFISGYAEDALDARGLFESEHNFMPKPVKPSELLKRVREILDH
CHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
P
C
>Mature Secondary Structure
MISVFIVDDNGQGMEKARALLRDHGYSVCDSDPEADDAMRFQFAMDRACIQVFWLFENGR
CEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEECCE
LVYVNEAACRSLGYGHEELAGMTVYDISPHCTVEEYAALWQQTRKQGVDRFEAVHQTRDG
EEEEEHHHHHHCCCCHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RTYPVEIQSNFVEFEGCEYCCCFVTDISERKRAEEKLLLHEFCIEKASIGIFLISMDGRI
CEEEEEEECCEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCE
AMANECACRSLGYSSDELCAMTVIDIDPAITVEKIRAIVEQLETNGSVTHETVHRHRDGT
EECCHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCC
TFPVEITTNNIEFHGATYSYSFAKDISGRKQAEEKRKLLETQLHQMQKLDAVGQLAGGIA
EEEEEEEECCEEEECCEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDFNNILTAIIGFAEVMDMRMEQGAPLRHHVRQILAAAERAADLTQGLLAFSRKQVLHVR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CLDLREIIDGLKKMLCRLIPEDIDFRVKTAATEMTVMADRGQIEQVLMNLVTNARDAMPG
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHCCCC
GGVLTIKTGTGVIDEEFVRTNGFGVMGNYALISVTDNGCGMNAETREKVFEPFFTTKRRG
CCEEEEECCCCCCCHHHHHCCCCEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
KGTGLGLSIIYGIVKQHDGFITVDSSPGQGATFRVYLPLAGREKEETREHRQTPLPKRGN
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCC
ETVLLVEDDEVVRELNRAVLEYAGYTVIETIDGREALERFREQSHRMDILVSDIIMPNLD
CEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GKALYDEIMKIRPDMKVLFISGYAEDALDARGLFESEHNFMPKPVKPSELLKRVREILDH
CHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA