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The map label for this gene is alr [H]

Identifier: 118581006

GI number: 118581006

Start: 2815485

End: 2816786

Strand: Reverse

Name: alr [H]

Synonym: Ppro_2594

Alternate gene names: 118581006

Gene position: 2816786-2815485 (Counterclockwise)

Preceding gene: 118581011

Following gene: 118581005

Centisome position: 70.28

GC content: 63.06

Gene sequence:

>1302_bases
ATGGTTGAGAGGGGTGGGAGAGGTGGGGCCAGCAATAGTCAAGAATCCTTGGCTTTTCCGATCCCTGATCACCTGTCTCC
TTTCCCGCTGTTTCCCTTTACAGCCGCCAAGAGACATGCTAATAAGCGGAACTGGATCTATTTGCCCGTTGTGAGGAGTT
TCGCTCTCTTGTACGATAGTCGTCCAACCTTTGCCGAGATCGACCTCTCGGCCCTGCGCCACAATTTTCAGCTCATCCGA
TCATCCGTTTCCCCACAGGCGGAACTGCTGGCGGTCGTCAAGGCCGACGCCTACGGACACGGCTTCATGGATATCAGCCG
CGAACTGGAGCGCTTGGGGGTGAATGCCTTTGGCGTGGCTTTTCTTGCCGAGGCGATCCAGCTACGCAAGGCCGGCATCG
ACAGGCCGATCCTGCTTCTGGGAGGTGTCTATCCCGGCCAGGAGCGCAAATGCATCGGCTACAACATCTCCACCATCGTC
TTCAATCTGGAGCAGGCCCGTGCTCTGGACCGTGCCGCCGCCAAGCTCTTCCGCAAGGCCCAGTTGCACCTCAAGGTGGA
TACCGGCATGGGGCGGCTGGGCATCCCCTATGCCGAGGTGCCGTCCTTCCTGCGCGAGCTGGCCGCCCTGCCGCACATCT
CCCTGGAAGGGGTAGTCTCCCATTTCGCCAGCGCCGACGAACTGAACGAGTCGGGGCGCTACTTCTCGCGGCTGCAGGCT
GAGCGTTTTGCCTGGGCCCTGGCTGAGACCCGTTCGGCCGGATTCGCGCCGCGCTACGTCCATATCGCCAACAGCGCGGC
AGGCCTGCTGAGAGATATTCCGGGATGCAACCTGGTCAGGCCCGGTATCGCCCTGTACGGCGCCCTGCCGTCGCCCGACT
TCCAGGGGCAGCTTGATCTGCGGCCGGTCATGCGCCTGAAGAGCCGCATTGCCATGTTGAAGTGGGTGGAGCCGGGCACC
CCCATCAGCTACGGTCGCCGCTTCACCACCGGAGGACGGACCCTGATCGCCAGCGTGCCGGTGGGCTATGCCGATGGCTA
TGTGCGCGCTCTCACCAACCGGGGAGAGGCGCTGGTGCGGGGAGAACGGGCACGGGTGGCGGGAACGGTCTGCATGGACT
GGATCATGCTGGACGTGACCGGTGTCAAAGGGGTGAGCGTGGGCGACCCGGTGGTGCTGATGGGGCCGGACGACTCCGGC
AACTGCATTCATGCCGAGGAACTGGCCGAGGCCGCCGGCACCATACCGTACGAGATCTTCTGCGGCATCAGCAAGCGGGT
GCCGCGGGTATATCTGAGCTGA

Upstream 100 bases:

>100_bases
AGGTTCAAAGGGTCTGATTCCACGGAATCATCTCAGTTCGGTCGAACTCCCCCAGGGCCTTACAACGCTGTTACCATACT
GGAACTCGCCTTTTCTGTCA

Downstream 100 bases:

>100_bases
GGGAGACGGCCCGAGCTGCGTGGGTAACCTGCAGCCCCCCGGACTCTCCTTCCTTTCGCTCCTGTCTCTGGTGGCGGAGT
TGCTGGCCTGCGGCATGGCT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MVERGGRGGASNSQESLAFPIPDHLSPFPLFPFTAAKRHANKRNWIYLPVVRSFALLYDSRPTFAEIDLSALRHNFQLIR
SSVSPQAELLAVVKADAYGHGFMDISRELERLGVNAFGVAFLAEAIQLRKAGIDRPILLLGGVYPGQERKCIGYNISTIV
FNLEQARALDRAAAKLFRKAQLHLKVDTGMGRLGIPYAEVPSFLRELAALPHISLEGVVSHFASADELNESGRYFSRLQA
ERFAWALAETRSAGFAPRYVHIANSAAGLLRDIPGCNLVRPGIALYGALPSPDFQGQLDLRPVMRLKSRIAMLKWVEPGT
PISYGRRFTTGGRTLIASVPVGYADGYVRALTNRGEALVRGERARVAGTVCMDWIMLDVTGVKGVSVGDPVVLMGPDDSG
NCIHAEELAEAAGTIPYEIFCGISKRVPRVYLS

Sequences:

>Translated_433_residues
MVERGGRGGASNSQESLAFPIPDHLSPFPLFPFTAAKRHANKRNWIYLPVVRSFALLYDSRPTFAEIDLSALRHNFQLIR
SSVSPQAELLAVVKADAYGHGFMDISRELERLGVNAFGVAFLAEAIQLRKAGIDRPILLLGGVYPGQERKCIGYNISTIV
FNLEQARALDRAAAKLFRKAQLHLKVDTGMGRLGIPYAEVPSFLRELAALPHISLEGVVSHFASADELNESGRYFSRLQA
ERFAWALAETRSAGFAPRYVHIANSAAGLLRDIPGCNLVRPGIALYGALPSPDFQGQLDLRPVMRLKSRIAMLKWVEPGT
PISYGRRFTTGGRTLIASVPVGYADGYVRALTNRGEALVRGERARVAGTVCMDWIMLDVTGVKGVSVGDPVVLMGPDDSG
NCIHAEELAEAAGTIPYEIFCGISKRVPRVYLS
>Mature_433_residues
MVERGGRGGASNSQESLAFPIPDHLSPFPLFPFTAAKRHANKRNWIYLPVVRSFALLYDSRPTFAEIDLSALRHNFQLIR
SSVSPQAELLAVVKADAYGHGFMDISRELERLGVNAFGVAFLAEAIQLRKAGIDRPILLLGGVYPGQERKCIGYNISTIV
FNLEQARALDRAAAKLFRKAQLHLKVDTGMGRLGIPYAEVPSFLRELAALPHISLEGVVSHFASADELNESGRYFSRLQA
ERFAWALAETRSAGFAPRYVHIANSAAGLLRDIPGCNLVRPGIALYGALPSPDFQGQLDLRPVMRLKSRIAMLKWVEPGT
PISYGRRFTTGGRTLIASVPVGYADGYVRALTNRGEALVRGERARVAGTVCMDWIMLDVTGVKGVSVGDPVVLMGPDDSG
NCIHAEELAEAAGTIPYEIFCGISKRVPRVYLS

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=375, Percent_Identity=35.2, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1790487, Length=371, Percent_Identity=34.5013477088949, Blast_Score=170, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 47276; Mature: 47276

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVERGGRGGASNSQESLAFPIPDHLSPFPLFPFTAAKRHANKRNWIYLPVVRSFALLYDS
CCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHCC
RPTFAEIDLSALRHNFQLIRSSVSPQAELLAVVKADAYGHGFMDISRELERLGVNAFGVA
CCCHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHH
FLAEAIQLRKAGIDRPILLLGGVYPGQERKCIGYNISTIVFNLEQARALDRAAAKLFRKA
HHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCHHHEEEEHHHHHHHHHHHHHHHHHH
QLHLKVDTGMGRLGIPYAEVPSFLRELAALPHISLEGVVSHFASADELNESGRYFSRLQA
EEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHCCHHHHHHHH
ERFAWALAETRSAGFAPRYVHIANSAAGLLRDIPGCNLVRPGIALYGALPSPDFQGQLDL
HHHHHHHHHHHCCCCCCCEEEECCHHHHHHHCCCCCCEECCCHHEEECCCCCCCCCCCCC
RPVMRLKSRIAMLKWVEPGTPISYGRRFTTGGRTLIASVPVGYADGYVRALTNRGEALVR
HHHHHHHHHHHHHEECCCCCCHHCCCEEECCCCEEEEECCCCCCCHHHHHHHCCCCEEEE
GERARVAGTVCMDWIMLDVTGVKGVSVGDPVVLMGPDDSGNCIHAEELAEAAGTIPYEIF
CCHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEECCCCCCCEECHHHHHHHHCCCCCEEE
CGISKRVPRVYLS
ECCHHCCCEEECC
>Mature Secondary Structure
MVERGGRGGASNSQESLAFPIPDHLSPFPLFPFTAAKRHANKRNWIYLPVVRSFALLYDS
CCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHCC
RPTFAEIDLSALRHNFQLIRSSVSPQAELLAVVKADAYGHGFMDISRELERLGVNAFGVA
CCCHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHH
FLAEAIQLRKAGIDRPILLLGGVYPGQERKCIGYNISTIVFNLEQARALDRAAAKLFRKA
HHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCHHHEEEEHHHHHHHHHHHHHHHHHH
QLHLKVDTGMGRLGIPYAEVPSFLRELAALPHISLEGVVSHFASADELNESGRYFSRLQA
EEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHCCHHHHHHHH
ERFAWALAETRSAGFAPRYVHIANSAAGLLRDIPGCNLVRPGIALYGALPSPDFQGQLDL
HHHHHHHHHHHCCCCCCCEEEECCHHHHHHHCCCCCCEECCCHHEEECCCCCCCCCCCCC
RPVMRLKSRIAMLKWVEPGTPISYGRRFTTGGRTLIASVPVGYADGYVRALTNRGEALVR
HHHHHHHHHHHHHEECCCCCCHHCCCEEECCCCEEEEECCCCCCCHHHHHHHCCCCEEEE
GERARVAGTVCMDWIMLDVTGVKGVSVGDPVVLMGPDDSGNCIHAEELAEAAGTIPYEIF
CCHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEECCCCCCCEECHHHHHHHHCCCCCEEE
CGISKRVPRVYLS
ECCHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA