Click here to switch to the map view.

The map label for this gene is aroF [H]

Identifier: 118580962

GI number: 118580962

Start: 2763424

End: 2764476

Strand: Direct

Name: aroF [H]

Synonym: Ppro_2550

Alternate gene names: 118580962

Gene position: 2763424-2764476 (Clockwise)

Preceding gene: 118580954

Following gene: 118580964

Centisome position: 68.95

GC content: 60.97

Gene sequence:

>1053_bases
ATGATCAAAACCAACAACCTGAATGTCTCCGCAATCACCCCCATCATCGCCCCGGCCGAACTGCGCCAGGTCTTCCCTCT
TTCGGCAAAGGACAGGGATTTCGTCAGCAGGAGCCGCGGCCAGATCAAGGATATCCTTCAGCGTAACGACCGGCGCCTGA
TGGTGGTTGTGGGCCCCTGTTCGATCCACGATACCGAGGCAGCCAAGGAGTATGCCAGGCGACTGGCCGACCTCTCCCGG
CGGGTGAGCGACCAGTTGCTGCTGGTCATGCGGGTCTACTTCGAAAAGCCGCGCACCACCATTGGTTGGAAAGGGCTGAT
CAACGACCCGGACATGAACCACACCCACCTGATTTCCAAGGGGCTGGGCATTGCCCGCGGCCTTTTGGGCTGGATAACCG
CCCTGGAGGTGCCGGTGGCCAACGAGATGCTCGACCCGATCACGCCCGAGTACGTTGCCGACATGATCAGCTGGGGCGCC
ATCGGAGCCCGCACCACCGAATCCCAGACCCATCGCGAGATGGCCAGCGGCCTCTCCTTTCCGGTGGGGTTCAAGAACGG
AACCGACGGCAACCTGCAGATCGCCATGGACGCCATGAAGGCAGCCCAGCACCCCCACAGCTTCCTTGGCATCAACCGCG
AGGGGCGCACCTCCATCATCCAGACCACCGGAAACCCGGATGTGCACATCGTCCTGCGCGGCGGTAGCCGCAAATCCAAC
TACCATGCCGAAGACATCAGACTCGTGGAGGAGTGCCTGGAGAAAAACCAGCTCTTCCCCACCATCATGGTGGACTGCAG
CCACGGCAACTCCAACAAGGATTACCAGAGGCAGGCCTTGGTGCTGGATGACATCGTCCAGCAGGTCGTGGACGGCAACA
ACTCCATCTCGGGGGTCATGCTGGAGAGCTTCCTCTCAGCCGGCAACCAGAAGATACCGACGGACACCAGCCAGCTCAAG
TACGGCGTTTCCATCACCGACGCCTGCATCGACTGGGAGACCACCGAGCGCATCCTCTTGGACGCCCATGCCAAACTGAA
AGAGAGACGGTGA

Upstream 100 bases:

>100_bases
AAGACCGCCCGCCGCATAGTAAAACTCCTTTGACAAACCACCGTGAAACCGATAACAATAGCCGGTCAGCCGGCAAATCC
ACGAAAACGGACCATGAACC

Downstream 100 bases:

>100_bases
GGGACAAAGGGTTAGGCGTCAGAGGTAAGGGGTAAGGAGCAGGCCTCCCTCACTTCCTCACTCCCTCCCGTACATCAGCA
GCATGCCCCCGCTGGCCCTT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MIKTNNLNVSAITPIIAPAELRQVFPLSAKDRDFVSRSRGQIKDILQRNDRRLMVVVGPCSIHDTEAAKEYARRLADLSR
RVSDQLLLVMRVYFEKPRTTIGWKGLINDPDMNHTHLISKGLGIARGLLGWITALEVPVANEMLDPITPEYVADMISWGA
IGARTTESQTHREMASGLSFPVGFKNGTDGNLQIAMDAMKAAQHPHSFLGINREGRTSIIQTTGNPDVHIVLRGGSRKSN
YHAEDIRLVEECLEKNQLFPTIMVDCSHGNSNKDYQRQALVLDDIVQQVVDGNNSISGVMLESFLSAGNQKIPTDTSQLK
YGVSITDACIDWETTERILLDAHAKLKERR

Sequences:

>Translated_350_residues
MIKTNNLNVSAITPIIAPAELRQVFPLSAKDRDFVSRSRGQIKDILQRNDRRLMVVVGPCSIHDTEAAKEYARRLADLSR
RVSDQLLLVMRVYFEKPRTTIGWKGLINDPDMNHTHLISKGLGIARGLLGWITALEVPVANEMLDPITPEYVADMISWGA
IGARTTESQTHREMASGLSFPVGFKNGTDGNLQIAMDAMKAAQHPHSFLGINREGRTSIIQTTGNPDVHIVLRGGSRKSN
YHAEDIRLVEECLEKNQLFPTIMVDCSHGNSNKDYQRQALVLDDIVQQVVDGNNSISGVMLESFLSAGNQKIPTDTSQLK
YGVSITDACIDWETTERILLDAHAKLKERR
>Mature_350_residues
MIKTNNLNVSAITPIIAPAELRQVFPLSAKDRDFVSRSRGQIKDILQRNDRRLMVVVGPCSIHDTEAAKEYARRLADLSR
RVSDQLLLVMRVYFEKPRTTIGWKGLINDPDMNHTHLISKGLGIARGLLGWITALEVPVANEMLDPITPEYVADMISWGA
IGARTTESQTHREMASGLSFPVGFKNGTDGNLQIAMDAMKAAQHPHSFLGINREGRTSIIQTTGNPDVHIVLRGGSRKSN
YHAEDIRLVEECLEKNQLFPTIMVDCSHGNSNKDYQRQALVLDDIVQQVVDGNNSISGVMLESFLSAGNQKIPTDTSQLK
YGVSITDACIDWETTERILLDAHAKLKERR

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=342, Percent_Identity=54.3859649122807, Blast_Score=393, Evalue=1e-111,
Organism=Escherichia coli, GI1786969, Length=348, Percent_Identity=50.8620689655172, Blast_Score=353, Evalue=8e-99,
Organism=Escherichia coli, GI1787996, Length=339, Percent_Identity=51.0324483775811, Blast_Score=350, Evalue=8e-98,
Organism=Saccharomyces cerevisiae, GI6320240, Length=349, Percent_Identity=50.1432664756447, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6319726, Length=338, Percent_Identity=50.887573964497, Blast_Score=356, Evalue=4e-99,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38953; Mature: 38953

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTNNLNVSAITPIIAPAELRQVFPLSAKDRDFVSRSRGQIKDILQRNDRRLMVVVGPC
CCCCCCCCEEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCC
SIHDTEAAKEYARRLADLSRRVSDQLLLVMRVYFEKPRTTIGWKGLINDPDMNHTHLISK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
GLGIARGLLGWITALEVPVANEMLDPITPEYVADMISWGAIGARTTESQTHREMASGLSF
HHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
PVGFKNGTDGNLQIAMDAMKAAQHPHSFLGINREGRTSIIQTTGNPDVHIVLRGGSRKSN
CCCCCCCCCCCEEEHHHHHHHHCCCHHHCCCCCCCCCEEEEECCCCCEEEEEECCCCCCC
YHAEDIRLVEECLEKNQLFPTIMVDCSHGNSNKDYQRQALVLDDIVQQVVDGNNSISGVM
CCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
LESFLSAGNQKIPTDTSQLKYGVSITDACIDWETTERILLDAHAKLKERR
HHHHHHCCCCCCCCCHHHEEECCEEEHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKTNNLNVSAITPIIAPAELRQVFPLSAKDRDFVSRSRGQIKDILQRNDRRLMVVVGPC
CCCCCCCCEEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCC
SIHDTEAAKEYARRLADLSRRVSDQLLLVMRVYFEKPRTTIGWKGLINDPDMNHTHLISK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
GLGIARGLLGWITALEVPVANEMLDPITPEYVADMISWGAIGARTTESQTHREMASGLSF
HHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
PVGFKNGTDGNLQIAMDAMKAAQHPHSFLGINREGRTSIIQTTGNPDVHIVLRGGSRKSN
CCCCCCCCCCCEEEHHHHHHHHCCCHHHCCCCCCCCCEEEEECCCCCEEEEEECCCCCCC
YHAEDIRLVEECLEKNQLFPTIMVDCSHGNSNKDYQRQALVLDDIVQQVVDGNNSISGVM
CCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
LESFLSAGNQKIPTDTSQLKYGVSITDACIDWETTERILLDAHAKLKERR
HHHHHHCCCCCCCCCHHHEEECCEEEHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]