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The map label for this gene is gcp

Identifier: 118580906

GI number: 118580906

Start: 2700577

End: 2701599

Strand: Reverse

Name: gcp

Synonym: Ppro_2493

Alternate gene names: 118580906

Gene position: 2701599-2700577 (Counterclockwise)

Preceding gene: 118580907

Following gene: 118580905

Centisome position: 67.41

GC content: 67.06

Gene sequence:

>1023_bases
ATGCTCGTTCTTGCCATTGAAACATCCTGCGATGAAACCGCCGCCGCACTGGTGGATGGCGGCCGCCGCATACTCTCCTC
GGTGGTCTCCTCCCAGGTGGCCATCCACGCCGAATATGGCGGGGTCGTGCCGGAGATCGCCTCCCGCAAGCATCTGGAGA
TGATCTCTCCGGTGATTTCCCAAGCCCTGGCCGAGGCCGGCGTCAGCTTCGGCGATATCCAGGGGGTGGCGGTTACCCGC
GGCCCGGGACTGTCCGGGGCGCTGCTTGTGGGGCTCTCGGCCGCCAAGGCCATCGCCTGCGCCCGCGGCATACCCTTCGT
GGGGGTGCACCACATCGAGGGGCACCTCTTCGCCCCCTTCCTGGAGCGACCGGTGGAGTTCCCCTTTCTGGCGCTGGTGG
TGTCGGGCGGCCACACCCACCTCTACCTGGTGGAGGGATTCGGCCGCTACCGCACCCTGGGAAGAACCCTTGATGACGCG
GCAGGCGAGGCCTTCGACAAGTCGGCCAAGATCATGGGGCTCCCCTATCCCGGCGGGGCCAGGATAGACGCCATGGCGCA
AGAGGGGAGCCCCGGGGCAATTCGGCTTCCCCGGCCGCTCTTGGCCGATGGCGGCCTGAATTTCAGTTTCAGCGGCCTCA
AGACCGCCATGCTGAACCGCATCACCAAGCATCCGGTCAGTATTCCCGGTGCCGAGGCCAACGACCTGTGCGCCTCGTTC
CAGCAGGCGGTCTGCGATGTGCTGGTTGCCAAGACCGCTGCCGCCCTGGAACGGACCGGGGTGACGCGTCTTGTGGTTGC
CGGCGGAGTGGCCTGCAACAGCGGCCTCAGGCGGAGCATGCAGGCCCTGGCCTCCGGGCTCTCCATTGACCTGCGTATCC
CGGCTCCGGCACTGTGCGGCGACAATGCCGCCATGCTGGCGGTTCCGGGAAACCACTACCTGGAGCAGGGCCATGCCTCG
GAGCTGAGCATGGATGTCACCGCCACCTGGGACATGGACCGGGTGGGGGAGGGGCGGTCATGA

Upstream 100 bases:

>100_bases
CCCTCACCAGGGGAGAGCGCTCGGAACTGGCCGAGCTGGCGGCAAACCTGCTCTGAACCCTGTACCCCTTATCTGTAATA
GGTAATAGAAGGTCATCCGA

Downstream 100 bases:

>100_bases
GCAGTGGACGGCGGCCCCTCAAGTCTCTGGGGCAGAACTTCCTGGTGGACCGGAATATTGTGGAGCGGATCATCCGCGGC
GCGGCCCTGGAGCCGGACGA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLVLAIETSCDETAAALVDGGRRILSSVVSSQVAIHAEYGGVVPEIASRKHLEMISPVISQALAEAGVSFGDIQGVAVTR
GPGLSGALLVGLSAAKAIACARGIPFVGVHHIEGHLFAPFLERPVEFPFLALVVSGGHTHLYLVEGFGRYRTLGRTLDDA
AGEAFDKSAKIMGLPYPGGARIDAMAQEGSPGAIRLPRPLLADGGLNFSFSGLKTAMLNRITKHPVSIPGAEANDLCASF
QQAVCDVLVAKTAAALERTGVTRLVVAGGVACNSGLRRSMQALASGLSIDLRIPAPALCGDNAAMLAVPGNHYLEQGHAS
ELSMDVTATWDMDRVGEGRS

Sequences:

>Translated_340_residues
MLVLAIETSCDETAAALVDGGRRILSSVVSSQVAIHAEYGGVVPEIASRKHLEMISPVISQALAEAGVSFGDIQGVAVTR
GPGLSGALLVGLSAAKAIACARGIPFVGVHHIEGHLFAPFLERPVEFPFLALVVSGGHTHLYLVEGFGRYRTLGRTLDDA
AGEAFDKSAKIMGLPYPGGARIDAMAQEGSPGAIRLPRPLLADGGLNFSFSGLKTAMLNRITKHPVSIPGAEANDLCASF
QQAVCDVLVAKTAAALERTGVTRLVVAGGVACNSGLRRSMQALASGLSIDLRIPAPALCGDNAAMLAVPGNHYLEQGHAS
ELSMDVTATWDMDRVGEGRS
>Mature_340_residues
MLVLAIETSCDETAAALVDGGRRILSSVVSSQVAIHAEYGGVVPEIASRKHLEMISPVISQALAEAGVSFGDIQGVAVTR
GPGLSGALLVGLSAAKAIACARGIPFVGVHHIEGHLFAPFLERPVEFPFLALVVSGGHTHLYLVEGFGRYRTLGRTLDDA
AGEAFDKSAKIMGLPYPGGARIDAMAQEGSPGAIRLPRPLLADGGLNFSFSGLKTAMLNRITKHPVSIPGAEANDLCASF
QQAVCDVLVAKTAAALERTGVTRLVVAGGVACNSGLRRSMQALASGLSIDLRIPAPALCGDNAAMLAVPGNHYLEQGHAS
ELSMDVTATWDMDRVGEGRS

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=337, Percent_Identity=35.6083086053413, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI8923380, Length=299, Percent_Identity=30.7692307692308, Blast_Score=121, Evalue=9e-28,
Organism=Escherichia coli, GI1789445, Length=331, Percent_Identity=46.8277945619335, Blast_Score=292, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17557464, Length=327, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI71995670, Length=339, Percent_Identity=27.7286135693215, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320099, Length=344, Percent_Identity=30.8139534883721, Blast_Score=142, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6322891, Length=312, Percent_Identity=27.5641025641026, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI20129063, Length=352, Percent_Identity=33.2386363636364, Blast_Score=171, Evalue=8e-43,
Organism=Drosophila melanogaster, GI21357207, Length=327, Percent_Identity=28.4403669724771, Blast_Score=118, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_PELPD (A1ARX8)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902156.1
- ProteinModelPortal:   A1ARX8
- SMR:   A1ARX8
- STRING:   A1ARX8
- MEROPS:   M22.001
- GeneID:   4573947
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2493
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   A1ARX8
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 35227; Mature: 35227

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLAIETSCDETAAALVDGGRRILSSVVSSQVAIHAEYGGVVPEIASRKHLEMISPVIS
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHCHHHHHHHHHHHH
QALAEAGVSFGDIQGVAVTRGPGLSGALLVGLSAAKAIACARGIPFVGVHHIEGHLFAPF
HHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEECHH
LERPVEFPFLALVVSGGHTHLYLVEGFGRYRTLGRTLDDAAGEAFDKSAKIMGLPYPGGA
HCCCCCCCEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC
RIDAMAQEGSPGAIRLPRPLLADGGLNFSFSGLKTAMLNRITKHPVSIPGAEANDLCASF
CEEEECCCCCCCEEECCCCCEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
QQAVCDVLVAKTAAALERTGVTRLVVAGGVACNSGLRRSMQALASGLSIDLRIPAPALCG
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEC
DNAAMLAVPGNHYLEQGHASELSMDVTATWDMDRVGEGRS
CCEEEEEECCCHHHHCCCCCCEEEEEEEECCHHHCCCCCC
>Mature Secondary Structure
MLVLAIETSCDETAAALVDGGRRILSSVVSSQVAIHAEYGGVVPEIASRKHLEMISPVIS
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHCHHHHHHHHHHHH
QALAEAGVSFGDIQGVAVTRGPGLSGALLVGLSAAKAIACARGIPFVGVHHIEGHLFAPF
HHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEECHH
LERPVEFPFLALVVSGGHTHLYLVEGFGRYRTLGRTLDDAAGEAFDKSAKIMGLPYPGGA
HCCCCCCCEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC
RIDAMAQEGSPGAIRLPRPLLADGGLNFSFSGLKTAMLNRITKHPVSIPGAEANDLCASF
CEEEECCCCCCCEEECCCCCEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
QQAVCDVLVAKTAAALERTGVTRLVVAGGVACNSGLRRSMQALASGLSIDLRIPAPALCG
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEC
DNAAMLAVPGNHYLEQGHASELSMDVTATWDMDRVGEGRS
CCEEEEEECCCHHHHCCCCCCEEEEEEEECCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA