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The map label for this gene is pimB [H]

Identifier: 118580870

GI number: 118580870

Start: 2656179

End: 2657339

Strand: Reverse

Name: pimB [H]

Synonym: Ppro_2457

Alternate gene names: 118580870

Gene position: 2657339-2656179 (Counterclockwise)

Preceding gene: 118580871

Following gene: 118580869

Centisome position: 66.3

GC content: 44.7

Gene sequence:

>1161_bases
ATGAAAACATTATTGATTTCAGAGATTTTTCCTCCAAAAATTGGTGGCAGTGGTCGTTGGTTTTGGGAGATATATTCTAG
GCTCGACTATGAATCCTATATTATTGCTGCTGGAAAAGATGCTTTTGCGACCGAATTTGATTTACAGCATTGTCTATGTT
GTATCCGCTGGCCTTTAGCTTTTTCAAGCTGGGGCTTGTTGTCTTTTTCTGCAATTGTACAGTACCTGAAACTAATAAAG
CTTCTGCACTTAACGGTAAAGCTCAAACATATTTCTGTAATTCATTGTGGTCGTGGTCTGCCGGAGGGGCTATTGGGCTG
GCTTGCATGGAAATGGCTCGGCATCCCCTATCTTTGTTATGTTCACGGGGAGGAATTGCCTACCTATCATAGTAGTAGGC
AATACAAACTCCTCTCTCAACTGGTTTATGCAAATGCACATCGTATCGTTGTAAATAGCAACAATACCCATCGCTCCTTT
GTCAAATATACGGGACTGTCTGATACCGTTCATATCATGCACCCGGGGGTTGATACCTCTTATTTCACTCCTGCAAATCG
AAATGAAGAAATCAGTCGAAAATATGGTTGGAGTGGGAGGAAGGTTGTCCTGACGGTCGGAAGGTTGCAAAAACGAAAGG
GACATGATCATGTGATATTGGCCATGGAGCGTATACGTCAAAGTATTCCCAATGTTCTATATTCTATCGTTGGTGATGGG
GAAGAGCTAGGTTACTTGGAATCTCTTGTTACTTCACATGGTCTTGGCGATTATGTGCAACTTCTCGGAAAAGTTGACGA
CGCAACTATGCTTGCCTGTTATCAACAGTGTGATCTGTTTGTTCTGGCTAATCGAGAGGTTGACGGAGACTTTGAGGGGT
TTGGCATGGTGCTGGTTGAAGCGCAGTCATGTGGTAAACCGGTTGTTGCCGGTATGTCGGGTGGTACGGCCGAAACCATG
ATCCAGGGTTATACCGGAATGCTGGTGGACGCTGAAAGCCCGGAAGCCATCGCAGATACTTTGACGCAATTGCTTTCCGA
TGACGAAATATTAAGAGTTATGGGACACTTTGCCGCGGAATGGGTCCGCCGGAAATTTGACTGGAATGTGTTGATTCGGC
AGGCGGAAGGAATTTTTTCTGAGCTTTCCTCTAAGAGATGA

Upstream 100 bases:

>100_bases
AATTTTCTCCTGTTGTAAGAAAAGCCTTGAACCCCAGTCCTGGTAATCGTTATTCGAATGTAATTGATATGGCCAAAGAT
TTTTTTAAAGTTGCTACAGT

Downstream 100 bases:

>100_bases
AAAGTCCTGTGTTGAAAAGATGTCTTTGGGCTGTACCAGCTTTAATGCTTATCGGGGTATTGCTCATATCCTGGCATTAC
AGTAAAAGCCCTCTCGAAGT

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKTLLISEIFPPKIGGSGRWFWEIYSRLDYESYIIAAGKDAFATEFDLQHCLCCIRWPLAFSSWGLLSFSAIVQYLKLIK
LLHLTVKLKHISVIHCGRGLPEGLLGWLAWKWLGIPYLCYVHGEELPTYHSSRQYKLLSQLVYANAHRIVVNSNNTHRSF
VKYTGLSDTVHIMHPGVDTSYFTPANRNEEISRKYGWSGRKVVLTVGRLQKRKGHDHVILAMERIRQSIPNVLYSIVGDG
EELGYLESLVTSHGLGDYVQLLGKVDDATMLACYQQCDLFVLANREVDGDFEGFGMVLVEAQSCGKPVVAGMSGGTAETM
IQGYTGMLVDAESPEAIADTLTQLLSDDEILRVMGHFAAEWVRRKFDWNVLIRQAEGIFSELSSKR

Sequences:

>Translated_386_residues
MKTLLISEIFPPKIGGSGRWFWEIYSRLDYESYIIAAGKDAFATEFDLQHCLCCIRWPLAFSSWGLLSFSAIVQYLKLIK
LLHLTVKLKHISVIHCGRGLPEGLLGWLAWKWLGIPYLCYVHGEELPTYHSSRQYKLLSQLVYANAHRIVVNSNNTHRSF
VKYTGLSDTVHIMHPGVDTSYFTPANRNEEISRKYGWSGRKVVLTVGRLQKRKGHDHVILAMERIRQSIPNVLYSIVGDG
EELGYLESLVTSHGLGDYVQLLGKVDDATMLACYQQCDLFVLANREVDGDFEGFGMVLVEAQSCGKPVVAGMSGGTAETM
IQGYTGMLVDAESPEAIADTLTQLLSDDEILRVMGHFAAEWVRRKFDWNVLIRQAEGIFSELSSKR
>Mature_386_residues
MKTLLISEIFPPKIGGSGRWFWEIYSRLDYESYIIAAGKDAFATEFDLQHCLCCIRWPLAFSSWGLLSFSAIVQYLKLIK
LLHLTVKLKHISVIHCGRGLPEGLLGWLAWKWLGIPYLCYVHGEELPTYHSSRQYKLLSQLVYANAHRIVVNSNNTHRSF
VKYTGLSDTVHIMHPGVDTSYFTPANRNEEISRKYGWSGRKVVLTVGRLQKRKGHDHVILAMERIRQSIPNVLYSIVGDG
EELGYLESLVTSHGLGDYVQLLGKVDDATMLACYQQCDLFVLANREVDGDFEGFGMVLVEAQSCGKPVVAGMSGGTAETM
IQGYTGMLVDAESPEAIADTLTQLLSDDEILRVMGHFAAEWVRRKFDWNVLIRQAEGIFSELSSKR

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose resid

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI32564184, Length=246, Percent_Identity=25.609756097561, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI9755344, Length=253, Percent_Identity=26.0869565217391, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357469, Length=262, Percent_Identity=24.8091603053435, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 43489; Mature: 43489

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLLISEIFPPKIGGSGRWFWEIYSRLDYESYIIAAGKDAFATEFDLQHCLCCIRWPLA
CCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
FSSWGLLSFSAIVQYLKLIKLLHLTVKLKHISVIHCGRGLPEGLLGWLAWKWLGIPYLCY
HCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEE
VHGEELPTYHSSRQYKLLSQLVYANAHRIVVNSNNTHRSFVKYTGLSDTVHIMHPGVDTS
EECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHEEECCCCCEEEEEECCCCCC
YFTPANRNEEISRKYGWSGRKVVLTVGRLQKRKGHDHVILAMERIRQSIPNVLYSIVGDG
CCCCCCCCHHHHHHCCCCCCEEEEEEHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCC
EELGYLESLVTSHGLGDYVQLLGKVDDATMLACYQQCDLFVLANREVDGDFEGFGMVLVE
HHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEE
AQSCGKPVVAGMSGGTAETMIQGYTGMLVDAESPEAIADTLTQLLSDDEILRVMGHFAAE
ECCCCCCEEECCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
WVRRKFDWNVLIRQAEGIFSELSSKR
HHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTLLISEIFPPKIGGSGRWFWEIYSRLDYESYIIAAGKDAFATEFDLQHCLCCIRWPLA
CCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
FSSWGLLSFSAIVQYLKLIKLLHLTVKLKHISVIHCGRGLPEGLLGWLAWKWLGIPYLCY
HCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEE
VHGEELPTYHSSRQYKLLSQLVYANAHRIVVNSNNTHRSFVKYTGLSDTVHIMHPGVDTS
EECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHEEECCCCCEEEEEECCCCCC
YFTPANRNEEISRKYGWSGRKVVLTVGRLQKRKGHDHVILAMERIRQSIPNVLYSIVGDG
CCCCCCCCHHHHHHCCCCCCEEEEEEHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCC
EELGYLESLVTSHGLGDYVQLLGKVDDATMLACYQQCDLFVLANREVDGDFEGFGMVLVE
HHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEE
AQSCGKPVVAGMSGGTAETMIQGYTGMLVDAESPEAIADTLTQLLSDDEILRVMGHFAAE
ECCCCCCEEECCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
WVRRKFDWNVLIRQAEGIFSELSSKR
HHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA