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The map label for this gene is fnr [H]

Identifier: 118580857

GI number: 118580857

Start: 2643118

End: 2643834

Strand: Direct

Name: fnr [H]

Synonym: Ppro_2444

Alternate gene names: 118580857

Gene position: 2643118-2643834 (Clockwise)

Preceding gene: 118580850

Following gene: 118580892

Centisome position: 65.95

GC content: 58.02

Gene sequence:

>717_bases
ATGACTACCGCACCACCGAAAAAACGTAGCGATCAGATCCTTAACAGCATCCCCTTCTTTGCGGGGCTTTCCGATGCGGA
GCTGCAGGAACTGGAGTCCCAGATCAGGCGCAGGCAGATTTCGCGGAACGAGGTGGTGCTCTTCGAAGAGGACACGGCCA
ACTACATGTACATCGTCTATTCCGGCAAGGTCAGGGTGGTGAAGATCAACGTGGACGGACGTGAGCAGATCCTGGCCATC
CACAGGAAGCGGGATTTCTTCGGCGAGATGTCGCTCCTGGACGGCAAGACGTCGCCGGCCACGGTTATCGCCATGGAAGA
CTCGGAGATCGGGCTTTTGGAAAAGGACGACTTCGACCGGTTCATCGAGAACAACGACAAGATGCGGCGGCACATCATCG
ACATGCTCTGCTCCCAGCTGCGCGAGGCCTGGATGATGATCAGGATCATGAGCTTCGATAACGCCGAGAAGCGGATCATG
GCGGTGCTGGACCGCCTGCAGGATCTGTACGGCATAGGAGACGACCGGGGGAGGATCATCAACGTCAAGCTGACCCACCA
GCAGATCGCCAGCTACGCCTCGGTCACGCGCGAGACCGTGACCCGGGTGCTCAATCAGATGAAGAGCGAGGAGTTGATCC
GGGTTCTGGAGGGAAAGACGATCCTGCTGACGAAGAAATTCTACGACAGGTTCAGCAGCATCGCCCCGAGCCGCTGA

Upstream 100 bases:

>100_bases
AGGTCCGGGCGATGCTCTTCGGCAGCATCCCCCCGGAGCCTCGGGACCGGGAGGCAAGGCGCCACCGGCGCGGGAGCAGA
GAAGGGAAGGAGTGGAACCA

Downstream 100 bases:

>100_bases
ATCACCTACCATTTCCATCCCGCCCCTGGTCATCTCAACTATTCCCCCGGATTCATGTCAGTTTTTCACGTTTACCCGCG
CCGTCGCCTGCCGGCTGTTT

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTTAPPKKRSDQILNSIPFFAGLSDAELQELESQIRRRQISRNEVVLFEEDTANYMYIVYSGKVRVVKINVDGREQILAI
HRKRDFFGEMSLLDGKTSPATVIAMEDSEIGLLEKDDFDRFIENNDKMRRHIIDMLCSQLREAWMMIRIMSFDNAEKRIM
AVLDRLQDLYGIGDDRGRIINVKLTHQQIASYASVTRETVTRVLNQMKSEELIRVLEGKTILLTKKFYDRFSSIAPSR

Sequences:

>Translated_238_residues
MTTAPPKKRSDQILNSIPFFAGLSDAELQELESQIRRRQISRNEVVLFEEDTANYMYIVYSGKVRVVKINVDGREQILAI
HRKRDFFGEMSLLDGKTSPATVIAMEDSEIGLLEKDDFDRFIENNDKMRRHIIDMLCSQLREAWMMIRIMSFDNAEKRIM
AVLDRLQDLYGIGDDRGRIINVKLTHQQIASYASVTRETVTRVLNQMKSEELIRVLEGKTILLTKKFYDRFSSIAPSR
>Mature_237_residues
TTAPPKKRSDQILNSIPFFAGLSDAELQELESQIRRRQISRNEVVLFEEDTANYMYIVYSGKVRVVKINVDGREQILAIH
RKRDFFGEMSLLDGKTSPATVIAMEDSEIGLLEKDDFDRFIENNDKMRRHIIDMLCSQLREAWMMIRIMSFDNAEKRIMA
VLDRLQDLYGIGDDRGRIINVKLTHQQIASYASVTRETVTRVLNQMKSEELIRVLEGKTILLTKKFYDRFSSIAPSR

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27643; Mature: 27512

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAPPKKRSDQILNSIPFFAGLSDAELQELESQIRRRQISRNEVVLFEEDTANYMYIVY
CCCCCCCCHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEE
SGKVRVVKINVDGREQILAIHRKRDFFGEMSLLDGKTSPATVIAMEDSEIGLLEKDDFDR
ECCEEEEEEECCCHHHHHHHHHHHHHHHCHHHCCCCCCCEEEEEECCCCCCCCCCCHHHH
FIENNDKMRRHIIDMLCSQLREAWMMIRIMSFDNAEKRIMAVLDRLQDLYGIGDDRGRII
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEE
NVKLTHQQIASYASVTRETVTRVLNQMKSEELIRVLEGKTILLTKKFYDRFSSIAPSR
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTAPPKKRSDQILNSIPFFAGLSDAELQELESQIRRRQISRNEVVLFEEDTANYMYIVY
CCCCCCCHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEE
SGKVRVVKINVDGREQILAIHRKRDFFGEMSLLDGKTSPATVIAMEDSEIGLLEKDDFDR
ECCEEEEEEECCCHHHHHHHHHHHHHHHCHHHCCCCCCCEEEEEECCCCCCCCCCCHHHH
FIENNDKMRRHIIDMLCSQLREAWMMIRIMSFDNAEKRIMAVLDRLQDLYGIGDDRGRII
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEE
NVKLTHQQIASYASVTRETVTRVLNQMKSEELIRVLEGKTILLTKKFYDRFSSIAPSR
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8846791; 9384377 [H]