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The map label for this gene is tapB [H]

Identifier: 118580833

GI number: 118580833

Start: 2618218

End: 2619939

Strand: Reverse

Name: tapB [H]

Synonym: Ppro_2420

Alternate gene names: 118580833

Gene position: 2619939-2618218 (Counterclockwise)

Preceding gene: 118580834

Following gene: 118580832

Centisome position: 65.37

GC content: 61.73

Gene sequence:

>1722_bases
ATGACTCAATCCTATGGTCGCAGAAATATCGGCGCTATTCTCATGGAGCGCGGCTGTCTGACGGCGGAACAGCTCCCCGT
GGTGGTGGGGCAGCTGGAATCCAGCCGGCAGCGCTTCGGCGAGATCTGTATCCGCGAGGGTTTCGTCGGCGAACAGGACC
TGGCCCGGGCCCTGGCCGAGCAGTTTGATCTGGAATACGTGGATCTGGCCGGCTTCAGGATGAACGAGGAGCTGCTCAAC
AGCCTGCCCACCGATGCCATATACCGCTTCCGTTTCGTACCGCTGGCAATGGAGTCCGGCGTGCTCAGTGTGGCTGTCTC
CGATCCCACCGACGTGGTCAAGCTGGATGACCTGGAATTGCTGCTGGGCTGTCCGCTGAGCATCTCCGTTGCCACGGAAA
GCGCCGTCGCTTCGGTGATCAAAACCGGTGAGGGCACCCGCCGCGTGCTGCGGGAAGTCTCGGAAGACTTCATGCTGCAA
CTGGTCAGGGAGACCGACCGTGGGGAAGAGGTCCTCACGGTGGAGAACATCTCCGAAGACATCAGCCCGATCATCAAGCT
GATCAACACCACCCTGCTGGACGCGCTCAACCGCCGCGCCAGCGATATCCACATCGAAACCGGCCATGAAGGGGTGGAGA
TTAAGTACCGTATCGACGGCGTTCTCTACCGGGCCAGCGACCCCATCGACCTGCACCTCCAGGCCCCGATCATCTCGCGG
CTCAAGGTCATGAGCGAACTGGATATTTCCGAACGCCGCATCCCCCAGGACGGCCGCTTCAAGGTCCGTTTCGGCTCCAA
GTCCATCGACTTCCGCGTTTCCATCATGCCCAGCGCCCTGGGGGAGGATGCCGTTATCCGCATCCTGGACAAGGAGAGCA
TCGCCAACGACCTGAAGGGACTTTCCCTGGAAAACCTGGGCATCAGCGAACGCGAGATCAGGCGTTTCAGGAAAAAGATC
CGCGAGCCCTACGGCATGGTGCTGGTGACCGGGCCCACCGGTTCGGGCAAGACCACCACCCTCTACGCCGCCCTGACCGA
GATCCACACCGGCGAGGAGAAGATCATCACCATCGAGGATCCGGTGGAATACATGCTGCGCGGGGTGCTGCAAATTCCGG
TCAACGAGAAGAAGGGGCTGACCTTCGCCAAGGGGTTGCGCTCCATCCTGCGCCACGACCCGGACAAGATCATGGTGGGC
GAGATCCGCGACCCGGAAACCGCCCAGATCGCCGTGCAGTCGGCCCTGACCGGCCACCTGGTCTTTACCACCGTGCATGC
CAACAACGTCTTCGACGTCATCGGCCGTTTCATCCACATGGGGATCGACCCCTATAACTTCGTCTCCTGCCTGAACTGCG
TCATGGCACAGCGTCTGGTGCGGCGCGTCTGTCCCTCCTGCCGCCGTCCGGTGACCTATGGCGACGAAGAGCTTCTGGCT
GCCGGCGTGGATCCCCGGGTCGTGCGAGGGGTAACCCTCTACGAGGCCCATGGCTGCGAGGACTGCAACGGCACCGGCTA
CCGCGGTCGTTCGGCAATCGTGGAGCTGATGGAGCTGAACGACCGCATACGTGATCTGATCATCGGCAAGGTTCCGGCAA
CCCAGCTCAAGCAGGCGGCCCGCGAGTGCGGGGTGGTATTCCTGCGCGATTCGGCGGTGGAAAAGCTGATCCAGGGGGAT
ACAACCCTGAAAGAGATCAACCGTGTCACCTTCGTGGAGTAA

Upstream 100 bases:

>100_bases
CGGCGGTCATGGTTGTCATGGGGGTTGTCATCGGGGTCATCATCATCACCATGTACCTGCCGATCTTCAAGATCGCGGGA
ACGGTGGGGTAACATAGTAT

Downstream 100 bases:

>100_bases
CGGACAGGGGGGCAGGCAGCGTTTTCAGCGAACTTTGTTTTGTGTTTTCCGTCCGCATTACAGGATGAAATGACCATGCG
CTTTTCCGGTACGCTTTTCA

Product: type II secretion system protein E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MTQSYGRRNIGAILMERGCLTAEQLPVVVGQLESSRQRFGEICIREGFVGEQDLARALAEQFDLEYVDLAGFRMNEELLN
SLPTDAIYRFRFVPLAMESGVLSVAVSDPTDVVKLDDLELLLGCPLSISVATESAVASVIKTGEGTRRVLREVSEDFMLQ
LVRETDRGEEVLTVENISEDISPIIKLINTTLLDALNRRASDIHIETGHEGVEIKYRIDGVLYRASDPIDLHLQAPIISR
LKVMSELDISERRIPQDGRFKVRFGSKSIDFRVSIMPSALGEDAVIRILDKESIANDLKGLSLENLGISEREIRRFRKKI
REPYGMVLVTGPTGSGKTTTLYAALTEIHTGEEKIITIEDPVEYMLRGVLQIPVNEKKGLTFAKGLRSILRHDPDKIMVG
EIRDPETAQIAVQSALTGHLVFTTVHANNVFDVIGRFIHMGIDPYNFVSCLNCVMAQRLVRRVCPSCRRPVTYGDEELLA
AGVDPRVVRGVTLYEAHGCEDCNGTGYRGRSAIVELMELNDRIRDLIIGKVPATQLKQAARECGVVFLRDSAVEKLIQGD
TTLKEINRVTFVE

Sequences:

>Translated_573_residues
MTQSYGRRNIGAILMERGCLTAEQLPVVVGQLESSRQRFGEICIREGFVGEQDLARALAEQFDLEYVDLAGFRMNEELLN
SLPTDAIYRFRFVPLAMESGVLSVAVSDPTDVVKLDDLELLLGCPLSISVATESAVASVIKTGEGTRRVLREVSEDFMLQ
LVRETDRGEEVLTVENISEDISPIIKLINTTLLDALNRRASDIHIETGHEGVEIKYRIDGVLYRASDPIDLHLQAPIISR
LKVMSELDISERRIPQDGRFKVRFGSKSIDFRVSIMPSALGEDAVIRILDKESIANDLKGLSLENLGISEREIRRFRKKI
REPYGMVLVTGPTGSGKTTTLYAALTEIHTGEEKIITIEDPVEYMLRGVLQIPVNEKKGLTFAKGLRSILRHDPDKIMVG
EIRDPETAQIAVQSALTGHLVFTTVHANNVFDVIGRFIHMGIDPYNFVSCLNCVMAQRLVRRVCPSCRRPVTYGDEELLA
AGVDPRVVRGVTLYEAHGCEDCNGTGYRGRSAIVELMELNDRIRDLIIGKVPATQLKQAARECGVVFLRDSAVEKLIQGD
TTLKEINRVTFVE
>Mature_572_residues
TQSYGRRNIGAILMERGCLTAEQLPVVVGQLESSRQRFGEICIREGFVGEQDLARALAEQFDLEYVDLAGFRMNEELLNS
LPTDAIYRFRFVPLAMESGVLSVAVSDPTDVVKLDDLELLLGCPLSISVATESAVASVIKTGEGTRRVLREVSEDFMLQL
VRETDRGEEVLTVENISEDISPIIKLINTTLLDALNRRASDIHIETGHEGVEIKYRIDGVLYRASDPIDLHLQAPIISRL
KVMSELDISERRIPQDGRFKVRFGSKSIDFRVSIMPSALGEDAVIRILDKESIANDLKGLSLENLGISEREIRRFRKKIR
EPYGMVLVTGPTGSGKTTTLYAALTEIHTGEEKIITIEDPVEYMLRGVLQIPVNEKKGLTFAKGLRSILRHDPDKIMVGE
IRDPETAQIAVQSALTGHLVFTTVHANNVFDVIGRFIHMGIDPYNFVSCLNCVMAQRLVRRVCPSCRRPVTYGDEELLAA
GVDPRVVRGVTLYEAHGCEDCNGTGYRGRSAIVELMELNDRIRDLIIGKVPATQLKQAARECGVVFLRDSAVEKLIQGDT
TLKEINRVTFVE

Specific function: Involved in the translocation of the type IV pilin [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=432, Percent_Identity=42.8240740740741, Blast_Score=334, Evalue=8e-93,
Organism=Escherichia coli, GI1786296, Length=410, Percent_Identity=39.0243902439024, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI87082188, Length=150, Percent_Identity=40, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013374
- InterPro:   IPR007831
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E; PF05157 GSPII_E_N [H]

EC number: NA

Molecular weight: Translated: 63810; Mature: 63679

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSYGRRNIGAILMERGCLTAEQLPVVVGQLESSRQRFGEICIREGFVGEQDLARALAE
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QFDLEYVDLAGFRMNEELLNSLPTDAIYRFRFVPLAMESGVLSVAVSDPTDVVKLDDLEL
HHCCCEEECCCCCCCHHHHHCCCHHHHHHHEEEEEEECCCEEEEEECCCCCEEEECCCCE
LLGCPLSISVATESAVASVIKTGEGTRRVLREVSEDFMLQLVRETDRGEEVLTVENISED
ECCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
ISPIIKLINTTLLDALNRRASDIHIETGHEGVEIKYRIDGVLYRASDPIDLHLQAPIISR
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEEEEECCCCEEEEECCHHHHH
LKVMSELDISERRIPQDGRFKVRFGSKSIDFRVSIMPSALGEDAVIRILDKESIANDLKG
HHHHHHCCCHHHCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCEEEEECHHHHHHHHCC
LSLENLGISEREIRRFRKKIREPYGMVLVTGPTGSGKTTTLYAALTEIHTGEEKIITIED
CEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEHEEEHHHHCCCCCEEEEECC
PVEYMLRGVLQIPVNEKKGLTFAKGLRSILRHDPDKIMVGEIRDPETAQIAVQSALTGHL
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCEE
VFTTVHANNVFDVIGRFIHMGIDPYNFVSCLNCVMAQRLVRRVCPSCRRPVTYGDEELLA
EEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCHHHHH
AGVDPRVVRGVTLYEAHGCEDCNGTGYRGRSAIVELMELNDRIRDLIIGKVPATQLKQAA
CCCCHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RECGVVFLRDSAVEKLIQGDTTLKEINRVTFVE
HHCCEEEEEHHHHHHHHCCCCHHHHHCHHCCCC
>Mature Secondary Structure 
TQSYGRRNIGAILMERGCLTAEQLPVVVGQLESSRQRFGEICIREGFVGEQDLARALAE
CCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QFDLEYVDLAGFRMNEELLNSLPTDAIYRFRFVPLAMESGVLSVAVSDPTDVVKLDDLEL
HHCCCEEECCCCCCCHHHHHCCCHHHHHHHEEEEEEECCCEEEEEECCCCCEEEECCCCE
LLGCPLSISVATESAVASVIKTGEGTRRVLREVSEDFMLQLVRETDRGEEVLTVENISED
ECCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
ISPIIKLINTTLLDALNRRASDIHIETGHEGVEIKYRIDGVLYRASDPIDLHLQAPIISR
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEEEEECCCCEEEEECCHHHHH
LKVMSELDISERRIPQDGRFKVRFGSKSIDFRVSIMPSALGEDAVIRILDKESIANDLKG
HHHHHHCCCHHHCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCEEEEECHHHHHHHHCC
LSLENLGISEREIRRFRKKIREPYGMVLVTGPTGSGKTTTLYAALTEIHTGEEKIITIED
CEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEHEEEHHHHCCCCCEEEEECC
PVEYMLRGVLQIPVNEKKGLTFAKGLRSILRHDPDKIMVGEIRDPETAQIAVQSALTGHL
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCEE
VFTTVHANNVFDVIGRFIHMGIDPYNFVSCLNCVMAQRLVRRVCPSCRRPVTYGDEELLA
EEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCHHHHH
AGVDPRVVRGVTLYEAHGCEDCNGTGYRGRSAIVELMELNDRIRDLIIGKVPATQLKQAA
CCCCHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RECGVVFLRDSAVEKLIQGDTTLKEINRVTFVE
HHCCEEEEEHHHHHHHHCCCCHHHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8820654 [H]