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The map label for this gene is aroQ

Identifier: 118580775

GI number: 118580775

Start: 2553963

End: 2554412

Strand: Direct

Name: aroQ

Synonym: Ppro_2360

Alternate gene names: 118580775

Gene position: 2553963-2554412 (Clockwise)

Preceding gene: 118580774

Following gene: 118580787

Centisome position: 63.72

GC content: 61.33

Gene sequence:

>450_bases
ATGAAAAAGATACTCGTCCTCAACGGCATCAACCTGAACATGTTCGGCAAACGCGATCCCGCCCACTACGGAACAGCGAC
CCTGGAGCAGATCGACGCCAGGGTCGCCGCCTGGGGCGCGGAACTGGGCTTGCAGATCGACTGTTTCCAGACCAATCACG
AGGGGGAAATGGTTGAGCGCATCCACCGCGCTCACGAGGAAGGGGTGGATGCGCTCATCATCAACGCCGGCGCCTGGACC
CATTACAGCTACGGCATCGCCGATGCGCTGGCCATCTTGAAGGCGCCGGTCATCGAAGTGCACATGTCGAATATCCATGC
CCGGGAAGAATTCCGGCACCACTCGGTCATCGCCGGACTGGCCAGGGGGCAGATATGCGGCTTCGGCGTCGGTAGCTATC
ACCTGGCGCTGCTGGCGGCCTCCGAACTGCTGAACGCCGGACAGGAATAG

Upstream 100 bases:

>100_bases
TCCTCACCTGGACCGGCAGGAACCTGCCGCAGGCCGCCAAGCAGGCGGTGATTGACGCACTCACCGCCACGTAGCATCTC
CTCAAGACGGAAAGGGAGTT

Downstream 100 bases:

>100_bases
CTGTACGGCTGCCAGAGGGCGTGAAAACGTCGTAAAAGGGAGCTGTGCCGGGGGGAATGCGGTGGAGGCGTTGCGAGGCG
GGAGTTGAGACTGCCTGGAG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MKKILVLNGINLNMFGKRDPAHYGTATLEQIDARVAAWGAELGLQIDCFQTNHEGEMVERIHRAHEEGVDALIINAGAWT
HYSYGIADALAILKAPVIEVHMSNIHAREEFRHHSVIAGLARGQICGFGVGSYHLALLAASELLNAGQE

Sequences:

>Translated_149_residues
MKKILVLNGINLNMFGKRDPAHYGTATLEQIDARVAAWGAELGLQIDCFQTNHEGEMVERIHRAHEEGVDALIINAGAWT
HYSYGIADALAILKAPVIEVHMSNIHAREEFRHHSVIAGLARGQICGFGVGSYHLALLAASELLNAGQE
>Mature_149_residues
MKKILVLNGINLNMFGKRDPAHYGTATLEQIDARVAAWGAELGLQIDCFQTNHEGEMVERIHRAHEEGVDALIINAGAWT
HYSYGIADALAILKAPVIEVHMSNIHAREEFRHHSVIAGLARGQICGFGVGSYHLALLAASELLNAGQE

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_PELPD (A1ARJ7)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902025.1
- ProteinModelPortal:   A1ARJ7
- SMR:   A1ARJ7
- STRING:   A1ARJ7
- GeneID:   4575055
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2360
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   VHMSNIH
- ProtClustDB:   PRK05395
- HAMAP:   MF_00169
- InterPro:   IPR001874
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16249; Mature: 16249

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 23-23 ACT_SITE 101-101 BINDING 75-75 BINDING 81-81 BINDING 88-88 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILVLNGINLNMFGKRDPAHYGTATLEQIDARVAAWGAELGLQIDCFQTNHEGEMVER
CCEEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
IHRAHEEGVDALIINAGAWTHYSYGIADALAILKAPVIEVHMSNIHAREEFRHHSVIAGL
HHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHH
ARGQICGFGVGSYHLALLAASELLNAGQE
HCCCEEECCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKILVLNGINLNMFGKRDPAHYGTATLEQIDARVAAWGAELGLQIDCFQTNHEGEMVER
CCEEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
IHRAHEEGVDALIINAGAWTHYSYGIADALAILKAPVIEVHMSNIHAREEFRHHSVIAGL
HHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHH
ARGQICGFGVGSYHLALLAASELLNAGQE
HCCCEEECCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA