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The map label for this gene is coaE [H]

Identifier: 118580771

GI number: 118580771

Start: 2547738

End: 2548346

Strand: Reverse

Name: coaE [H]

Synonym: Ppro_2356

Alternate gene names: 118580771

Gene position: 2548346-2547738 (Counterclockwise)

Preceding gene: 118580773

Following gene: 118580770

Centisome position: 63.58

GC content: 64.04

Gene sequence:

>609_bases
ATGGGAGTCCGTGTGGTGGGCCTGACCGGTGGGATCGCAACCGGCAAGAGCAGTGTGGCCCGTTTTCTGATGGAGCGAGG
AGCGGTGGTGATCGATGCCGATGAACTGTCGCGCCTGGCGGTTCATCCGGGGAGTCCGGCCCTGGAGCGGATCGTTGATC
TGTTTGGCGCCGGTGTGCTGCTGCCGGACGGCAATCTGGACCGCCGGAAGATGCGTTCGCTGGTCTTCGGCAACGACGTG
AACCGTCGCCAGCTGGAAGGGATCGTGCATCCTGAGATCAGGAGGCTGGCGGAGGAGCGCATCGCAGCCGCGGCTTGCCG
GGGGGAGCGCATCGTGTTCTACATGGCGCCGCTGCTGATCGAGGCGGGAGTCACCAGCCGGGTGGACGAGATCTGGGTGG
TGACCCTGAGGCCCGAGATACAGATCCAGCGCTTGATGGAACGTGACGGCATCAGCCGGGAGGATGCCTGCAAGATCATT
GACAGCCAGATGCCGCTGGCCGAGAAGGAGCGCCATGGCCGCGTGATTATCGACAACAGCGGTACGCCCGAGGAGACGGA
ACGGCTGGTGGCGGACATATGGGAACGGGAAATGGGGGAACGAGCATGA

Upstream 100 bases:

>100_bases
CTCAAGCCAAAAATCTGTTAATTTGGCGGTCCCTTTGCTACACTGGCCACCTTTTCATGGAATATGCGGTGCCCTGGTGT
GGGCGCAAGGAGTACTAACG

Downstream 100 bases:

>100_bases
CCGAGAAGAAGCATATCCTCAGACGGGCGCCACGCCCGGAGCCGAAGCCGGACAGGGAGATGGAGTGCTTTGCCGCCGTG
CCGCGCGGCAGCGAGGACGT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MGVRVVGLTGGIATGKSSVARFLMERGAVVIDADELSRLAVHPGSPALERIVDLFGAGVLLPDGNLDRRKMRSLVFGNDV
NRRQLEGIVHPEIRRLAEERIAAAACRGERIVFYMAPLLIEAGVTSRVDEIWVVTLRPEIQIQRLMERDGISREDACKII
DSQMPLAEKERHGRVIIDNSGTPEETERLVADIWEREMGERA

Sequences:

>Translated_202_residues
MGVRVVGLTGGIATGKSSVARFLMERGAVVIDADELSRLAVHPGSPALERIVDLFGAGVLLPDGNLDRRKMRSLVFGNDV
NRRQLEGIVHPEIRRLAEERIAAAACRGERIVFYMAPLLIEAGVTSRVDEIWVVTLRPEIQIQRLMERDGISREDACKII
DSQMPLAEKERHGRVIIDNSGTPEETERLVADIWEREMGERA
>Mature_201_residues
GVRVVGLTGGIATGKSSVARFLMERGAVVIDADELSRLAVHPGSPALERIVDLFGAGVLLPDGNLDRRKMRSLVFGNDVN
RRQLEGIVHPEIRRLAEERIAAAACRGERIVFYMAPLLIEAGVTSRVDEIWVVTLRPEIQIQRLMERDGISREDACKIID
SQMPLAEKERHGRVIIDNSGTPEETERLVADIWEREMGERA

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=187, Percent_Identity=40.6417112299465, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI191252795, Length=187, Percent_Identity=40.6417112299465, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI110227607, Length=192, Percent_Identity=35.9375, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI110227605, Length=192, Percent_Identity=35.9375, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI110227603, Length=192, Percent_Identity=35.9375, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI110227601, Length=192, Percent_Identity=35.9375, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI205277394, Length=192, Percent_Identity=35.9375, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1786292, Length=187, Percent_Identity=36.3636363636364, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17554944, Length=183, Percent_Identity=36.0655737704918, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25143409, Length=184, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320402, Length=197, Percent_Identity=35.0253807106599, Blast_Score=106, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24644728, Length=191, Percent_Identity=35.6020942408377, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24658602, Length=193, Percent_Identity=33.6787564766839, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22475; Mature: 22344

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVRVVGLTGGIATGKSSVARFLMERGAVVIDADELSRLAVHPGSPALERIVDLFGAGVL
CCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEHHHHHHEEECCCCHHHHHHHHHHCCCEE
LPDGNLDRRKMRSLVFGNDVNRRQLEGIVHPEIRRLAEERIAAAACRGERIVFYMAPLLI
CCCCCCCHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHH
EAGVTSRVDEIWVVTLRPEIQIQRLMERDGISREDACKIIDSQMPLAEKERHGRVIIDNS
HCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCEEEECCC
GTPEETERLVADIWEREMGERA
CCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GVRVVGLTGGIATGKSSVARFLMERGAVVIDADELSRLAVHPGSPALERIVDLFGAGVL
CEEEEEECCCCCCCHHHHHHHHHHCCCEEEEHHHHHHEEECCCCHHHHHHHHHHCCCEE
LPDGNLDRRKMRSLVFGNDVNRRQLEGIVHPEIRRLAEERIAAAACRGERIVFYMAPLLI
CCCCCCCHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHH
EAGVTSRVDEIWVVTLRPEIQIQRLMERDGISREDACKIIDSQMPLAEKERHGRVIIDNS
HCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCEEEECCC
GTPEETERLVADIWEREMGERA
CCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA