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The map label for this gene is yoeA [H]

Identifier: 118580730

GI number: 118580730

Start: 2500933

End: 2502345

Strand: Direct

Name: yoeA [H]

Synonym: Ppro_2315

Alternate gene names: 118580730

Gene position: 2500933-2502345 (Clockwise)

Preceding gene: 118580729

Following gene: 118580731

Centisome position: 62.4

GC content: 63.84

Gene sequence:

>1413_bases
GTGCGAGCGGGGGAAGACTCTTCCATCCCCCGGTGGAGGCGGAGCAGTTACGTGCCCATGAAAAACGATCTTACCGCAGC
CCCCATCCCGCACCTGGTCAGGCGCCTGGCCATTCCCGCCGGGACCGGCTTCTTCTTCAACACCATGTTCAACGTGGTGG
ACACCTGGTACGGCGGCAAACTCTCCACCACCGCCCTGGCGGCCATGTCGCTCTCCTTCCCGGTGTTCTTCATCGTCCTC
GCCATGGGCACCGGCCTCTCCTCCGGCACAACGACCATGATCGGCAACGCCCTGGGGCGCGGCAACCGGGGGGAGGCGCG
CCGTTACGTCTCCCAGGCGCTCTCCTTCGGCCTGCTCAACGCCATTCTGCTGACCATGGCGGGGCTTGTGTGTGCCGAAC
CGATCTTCAGGTTCATGGGCGCCAGGAATGACTATCTCAGCCTGGCGGTCAGCTACATCGGCGTGATCTTCTGCGGCTCG
ATCGTCCTCATGCTCAACTTCGTCATGAGCGCCATCTTAAGCTCCCACGGCAACACCTGGACCTACCGGAATTTCCTGGT
GGGCGGCTTCTTCCTCAACCTTGCGCTGGATCCCTGGTTCATGTACGGTGGCCTGGGGCTCCCCCCCCTGGGGCTGCCCG
GCATCGCCCTCTCCACGGTGGTCATCCACGGCATGGGCACCGTCTTCCTCTTCAGCCGCCTCTTCCGTTCGGGAGTGATG
AATACCTTCAGGCCGCGTGAACTCTGGCCCAACTGGCGCTGCTACCGCGAACTGGCCAGGTACGGTTTCCCTTCGGCCCT
GAACATGATGACCATCAGCCTGGGAATATTCATCGTAACCTGGTTCGTGGGCGGCTACGGCAAGGAGGCGGTGGCCGCCT
ACGGCAGCGCCACCCGCATCGAACAGATCGCCCTGCTGCCGATCATGGGGCTAAACACCTCCACCCTGGCGCTCACCGCC
CAGAATTTCGGTGCGTTGCGCACGGACCGCATCCGCGAGGTCCTGCGGGTCTCGCTGCGCTACGGCTTCTCCCTGGCCAG
CATGGGAACCCTGGCGGCCCTGCTCATGACCAGCCAGCTCATGTCGCTGTTCAGCAACGACCCCCAGGTGATCGCCATCG
GCATCCGCTTCCTGCGCATCGAGGCTTTCGTCCTGCCTGCCTATGTGCTGCTCTACATCTGCATCTCCGCCATGCAGGGG
ATCAAGCAGCCGCTGTTCGCCCTCTGGGTCGGCCTGTACCGGCAGGTCGCCGGCCCCACCTGCGTCTTCCCGCTCCTGGC
CACGGCCTGCGGCTGGGGCATCCTCGGCATCTGGTGGGGCATCTTCGGCATAACCTGGTCCGCTGCCCTGATCGTGGTGG
CCTACGTCAGCTGGATACTGAAAAAGCTTGAAAAGGAACTCCCCGCCGTATGA

Upstream 100 bases:

>100_bases
CAACATCCACAAGTCCCCCGAGAAGAGCGGTCAGAGCAGAAGCAGGGTGGAGCTGAATGCCATCACCCAGTGACATGAAC
GACGGGAGTGCGCTCAAGGG

Downstream 100 bases:

>100_bases
AATCCGTCGCCATCGCAACCCTGGGATGCAAGACCAACCAGTTCGAATCCGCAGCCATGCTTGAGCAGTTCACCCGTTCC
GGCTACCGCGTCGTCCCCTT

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MRAGEDSSIPRWRRSSYVPMKNDLTAAPIPHLVRRLAIPAGTGFFFNTMFNVVDTWYGGKLSTTALAAMSLSFPVFFIVL
AMGTGLSSGTTTMIGNALGRGNRGEARRYVSQALSFGLLNAILLTMAGLVCAEPIFRFMGARNDYLSLAVSYIGVIFCGS
IVLMLNFVMSAILSSHGNTWTYRNFLVGGFFLNLALDPWFMYGGLGLPPLGLPGIALSTVVIHGMGTVFLFSRLFRSGVM
NTFRPRELWPNWRCYRELARYGFPSALNMMTISLGIFIVTWFVGGYGKEAVAAYGSATRIEQIALLPIMGLNTSTLALTA
QNFGALRTDRIREVLRVSLRYGFSLASMGTLAALLMTSQLMSLFSNDPQVIAIGIRFLRIEAFVLPAYVLLYICISAMQG
IKQPLFALWVGLYRQVAGPTCVFPLLATACGWGILGIWWGIFGITWSAALIVVAYVSWILKKLEKELPAV

Sequences:

>Translated_470_residues
MRAGEDSSIPRWRRSSYVPMKNDLTAAPIPHLVRRLAIPAGTGFFFNTMFNVVDTWYGGKLSTTALAAMSLSFPVFFIVL
AMGTGLSSGTTTMIGNALGRGNRGEARRYVSQALSFGLLNAILLTMAGLVCAEPIFRFMGARNDYLSLAVSYIGVIFCGS
IVLMLNFVMSAILSSHGNTWTYRNFLVGGFFLNLALDPWFMYGGLGLPPLGLPGIALSTVVIHGMGTVFLFSRLFRSGVM
NTFRPRELWPNWRCYRELARYGFPSALNMMTISLGIFIVTWFVGGYGKEAVAAYGSATRIEQIALLPIMGLNTSTLALTA
QNFGALRTDRIREVLRVSLRYGFSLASMGTLAALLMTSQLMSLFSNDPQVIAIGIRFLRIEAFVLPAYVLLYICISAMQG
IKQPLFALWVGLYRQVAGPTCVFPLLATACGWGILGIWWGIFGITWSAALIVVAYVSWILKKLEKELPAV
>Mature_470_residues
MRAGEDSSIPRWRRSSYVPMKNDLTAAPIPHLVRRLAIPAGTGFFFNTMFNVVDTWYGGKLSTTALAAMSLSFPVFFIVL
AMGTGLSSGTTTMIGNALGRGNRGEARRYVSQALSFGLLNAILLTMAGLVCAEPIFRFMGARNDYLSLAVSYIGVIFCGS
IVLMLNFVMSAILSSHGNTWTYRNFLVGGFFLNLALDPWFMYGGLGLPPLGLPGIALSTVVIHGMGTVFLFSRLFRSGVM
NTFRPRELWPNWRCYRELARYGFPSALNMMTISLGIFIVTWFVGGYGKEAVAAYGSATRIEQIALLPIMGLNTSTLALTA
QNFGALRTDRIREVLRVSLRYGFSLASMGTLAALLMTSQLMSLFSNDPQVIAIGIRFLRIEAFVLPAYVLLYICISAMQG
IKQPLFALWVGLYRQVAGPTCVFPLLATACGWGILGIWWGIFGITWSAALIVVAYVSWILKKLEKELPAV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=450, Percent_Identity=22.4444444444444, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51544; Mature: 51544

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]