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The map label for this gene is glmM

Identifier: 118580671

GI number: 118580671

Start: 2436065

End: 2437426

Strand: Direct

Name: glmM

Synonym: Ppro_2256

Alternate gene names: 118580671

Gene position: 2436065-2437426 (Clockwise)

Preceding gene: 118580670

Following gene: 118580672

Centisome position: 60.78

GC content: 63.14

Gene sequence:

>1362_bases
GTGAAAAAACTCTTCGGCACCGACGGCGTCCGCGGCGTCGCCAACGTCTACCCCATGACAACCGAGATGGCCATGCAACT
GGGCAGGGCCGCCGCCTATATCTTCAAGAGCTCAAGCAAGCGCCGCCACCGCATCGTGATCGGCAAGGACACGCGCCTCT
CCGGCTACATGCTGGAAAACGCCATGGTGGCCGGCATCTGCTCCATGGGAGTGGACGTGCTGCTGGTGGGGCCGCTTCCC
ACGCCGGGCATCGCCAACATCACCTCCTCCATGCGGGCCGACGCCGGCGTGGTCATATCAGCCTCCCACAACCCGTTCCA
GGACAACGGCATCAAGTTCTTCTCCGCCGACGGCTTCAAGCTGCCCGACCAGATCGAGCTGAAAATAGAGAAGCTGATCG
AGTCCAACAAGATCGACTCCCTGCGCCCCACGGCCAGCGAGGTGGGCAAGGCCTTCCGCATCGACGATGCCGCCGGCCGC
TACATCGTCTTCCTCAAGAACACCTTTCCCACTGAGATGGACCTCTCGGGCATGAAGATCGTGCTGGACTGCGCCAATGG
CGCCGCCTACCGGGTTGCTCCGGCGGTGTTCGAGGAGTTGGGGGCCGAGGTGATCTGCCTGGGGGTCAGCCCCAACGGCA
CCAACATCAACGCCGACTGCGGCTCGCTCTATCCCCAGGTGATCAGCGAGGCGGTGAAGAAGCACCGCGCCGATATCGGC
ATCGCCCTGGACGGCGACGCCGACCGGGTCATCGTCTGCGACGAGTTCGGCCACGAGGTGGACGGCGACCACATCATGGC
CATCTGCGCCACCGATATGCTCCGGCGCAAGCTTTTAAAAAAGAAGACCCTGGTAACGACGGTGATGAGCAACATGGGGC
TGGACATCGCCATGCGCGCGGCGGGCGGCAAGATCGTCAAGACGGCCGTGGGAGACCGCTACGTGGTTGAGGAGATGCGC
AAGGGTGGCTATAATCTGGGCGGGGAGCAGTCCGGCCACATGATCTTCCTGGACAGCAACACCACCGGCGACGGCATCCT
CTCGGCATTGCAGCTCCTGGCGGTCATGCGCAGGACGGAGAAGCCGCTCTCCGAACTGTCCGAGGTGATGATCGCGCTGC
CCCAGGTGCTGGTCAACACCCGGGTGCGCGAGAAGAAGGACATCACCACCATCCCGGAGATCGCCGCCAGGATCAGGGAC
GTTGAAGAGAAGCTGGGCAATGAGGGGCGGGTGCTGATCCGCTATTCCGGCACCGAGCCGCTGCTGCGGGTCATGCTGGA
GGGGAAGGACACCTACGAGATCACCGCCTGGGCCAACGAGATCATCGACCTGGTCAGGAAGCACCTGGGAGAAAAGCAGT
AA

Upstream 100 bases:

>100_bases
GCCTCAGGCTTCCGGAGGAGATCAGGGTAACCCGCGTCTCTCCAGGCCGGCTGGAACTGCGCCTGGAACCGGAACACTCA
CCACAAGGAGACAGACACCC

Downstream 100 bases:

>100_bases
CCCCGCCGGATTCGCAAGGAGACGAGAACATGGCAAAACTGGGACTCAACGTCGATCATGTGGCCACCGTGCGCCAGGCG
CGCGGCGGCATGGAGCCGGA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MKKLFGTDGVRGVANVYPMTTEMAMQLGRAAAYIFKSSSKRRHRIVIGKDTRLSGYMLENAMVAGICSMGVDVLLVGPLP
TPGIANITSSMRADAGVVISASHNPFQDNGIKFFSADGFKLPDQIELKIEKLIESNKIDSLRPTASEVGKAFRIDDAAGR
YIVFLKNTFPTEMDLSGMKIVLDCANGAAYRVAPAVFEELGAEVICLGVSPNGTNINADCGSLYPQVISEAVKKHRADIG
IALDGDADRVIVCDEFGHEVDGDHIMAICATDMLRRKLLKKKTLVTTVMSNMGLDIAMRAAGGKIVKTAVGDRYVVEEMR
KGGYNLGGEQSGHMIFLDSNTTGDGILSALQLLAVMRRTEKPLSELSEVMIALPQVLVNTRVREKKDITTIPEIAARIRD
VEEKLGNEGRVLIRYSGTEPLLRVMLEGKDTYEITAWANEIIDLVRKHLGEKQ

Sequences:

>Translated_453_residues
MKKLFGTDGVRGVANVYPMTTEMAMQLGRAAAYIFKSSSKRRHRIVIGKDTRLSGYMLENAMVAGICSMGVDVLLVGPLP
TPGIANITSSMRADAGVVISASHNPFQDNGIKFFSADGFKLPDQIELKIEKLIESNKIDSLRPTASEVGKAFRIDDAAGR
YIVFLKNTFPTEMDLSGMKIVLDCANGAAYRVAPAVFEELGAEVICLGVSPNGTNINADCGSLYPQVISEAVKKHRADIG
IALDGDADRVIVCDEFGHEVDGDHIMAICATDMLRRKLLKKKTLVTTVMSNMGLDIAMRAAGGKIVKTAVGDRYVVEEMR
KGGYNLGGEQSGHMIFLDSNTTGDGILSALQLLAVMRRTEKPLSELSEVMIALPQVLVNTRVREKKDITTIPEIAARIRD
VEEKLGNEGRVLIRYSGTEPLLRVMLEGKDTYEITAWANEIIDLVRKHLGEKQ
>Mature_453_residues
MKKLFGTDGVRGVANVYPMTTEMAMQLGRAAAYIFKSSSKRRHRIVIGKDTRLSGYMLENAMVAGICSMGVDVLLVGPLP
TPGIANITSSMRADAGVVISASHNPFQDNGIKFFSADGFKLPDQIELKIEKLIESNKIDSLRPTASEVGKAFRIDDAAGR
YIVFLKNTFPTEMDLSGMKIVLDCANGAAYRVAPAVFEELGAEVICLGVSPNGTNINADCGSLYPQVISEAVKKHRADIG
IALDGDADRVIVCDEFGHEVDGDHIMAICATDMLRRKLLKKKTLVTTVMSNMGLDIAMRAAGGKIVKTAVGDRYVVEEMR
KGGYNLGGEQSGHMIFLDSNTTGDGILSALQLLAVMRRTEKPLSELSEVMIALPQVLVNTRVREKKDITTIPEIAARIRD
VEEKLGNEGRVLIRYSGTEPLLRVMLEGKDTYEITAWANEIIDLVRKHLGEKQ

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Homo sapiens, GI21361621, Length=403, Percent_Identity=24.0694789081886, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI133922562, Length=358, Percent_Identity=24.5810055865922, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1789566, Length=448, Percent_Identity=50.2232142857143, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1788361, Length=438, Percent_Identity=28.310502283105, Blast_Score=135, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17535441, Length=372, Percent_Identity=23.1182795698925, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17864244, Length=403, Percent_Identity=25.5583126550869, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_PELPD (A1AR93)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901921.1
- ProteinModelPortal:   A1AR93
- SMR:   A1AR93
- STRING:   A1AR93
- GeneID:   4574980
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2256
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- PhylomeDB:   A1AR93
- ProtClustDB:   PRK14314
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 49366; Mature: 49366

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFGTDGVRGVANVYPMTTEMAMQLGRAAAYIFKSSSKRRHRIVIGKDTRLSGYMLEN
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHH
AMVAGICSMGVDVLLVGPLPTPGIANITSSMRADAGVVISASHNPFQDNGIKFFSADGFK
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCC
LPDQIELKIEKLIESNKIDSLRPTASEVGKAFRIDDAAGRYIVFLKNTFPTEMDLSGMKI
CCHHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCCCEE
VLDCANGAAYRVAPAVFEELGAEVICLGVSPNGTNINADCGSLYPQVISEAVKKHRADIG
EEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCEE
IALDGDADRVIVCDEFGHEVDGDHIMAICATDMLRRKLLKKKTLVTTVMSNMGLDIAMRA
EEECCCCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
AGGKIVKTAVGDRYVVEEMRKGGYNLGGEQSGHMIFLDSNTTGDGILSALQLLAVMRRTE
CCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
KPLSELSEVMIALPQVLVNTRVREKKDITTIPEIAARIRDVEEKLGNEGRVLIRYSGTEP
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCHH
LLRVMLEGKDTYEITAWANEIIDLVRKHLGEKQ
HHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKLFGTDGVRGVANVYPMTTEMAMQLGRAAAYIFKSSSKRRHRIVIGKDTRLSGYMLEN
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHH
AMVAGICSMGVDVLLVGPLPTPGIANITSSMRADAGVVISASHNPFQDNGIKFFSADGFK
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCC
LPDQIELKIEKLIESNKIDSLRPTASEVGKAFRIDDAAGRYIVFLKNTFPTEMDLSGMKI
CCHHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCCCEE
VLDCANGAAYRVAPAVFEELGAEVICLGVSPNGTNINADCGSLYPQVISEAVKKHRADIG
EEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCEE
IALDGDADRVIVCDEFGHEVDGDHIMAICATDMLRRKLLKKKTLVTTVMSNMGLDIAMRA
EEECCCCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
AGGKIVKTAVGDRYVVEEMRKGGYNLGGEQSGHMIFLDSNTTGDGILSALQLLAVMRRTE
CCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
KPLSELSEVMIALPQVLVNTRVREKKDITTIPEIAARIRDVEEKLGNEGRVLIRYSGTEP
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCHH
LLRVMLEGKDTYEITAWANEIIDLVRKHLGEKQ
HHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA