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The map label for this gene is zwf [H]

Identifier: 118580665

GI number: 118580665

Start: 2429288

End: 2430796

Strand: Direct

Name: zwf [H]

Synonym: Ppro_2250

Alternate gene names: 118580665

Gene position: 2429288-2430796 (Clockwise)

Preceding gene: 118580664

Following gene: 118580666

Centisome position: 60.61

GC content: 64.28

Gene sequence:

>1509_bases
ATGCCGTCATCCAGAAAGCTGGACCCGACCATCATCGTGATCTTCGGCGGCGGGGGGGATCTGACCAGGCGCAAACTCAT
TCCGGCGCTGCACAACCTCATGCTGGACAATCTGCTCCCCCAACGCTGCGCCATCATCGGCATCGGCCGGAGGAGCATGG
ACGACGACACCTTCCGCAACCATCTCAAAAGCGGCCTGGAACAGTTCTCCCGACGCGGTGGAAGCACAGAACAGCCCTGG
GACGATTTCGGCTCCCGGATCAGCTACGTCTCCGAGGACGTGACCTCGAAAGAGTCGGGGGCGGCCCTGACCCGACGCCT
GAACGAGATCGACAGCGACTGGGGGGTACGCGCCAACCGCATCTTCTACCTGGCAATCCCCCCCTCCATGATGGAGCCGG
CAGCCGCCATGCTGCAGCGCATGGGGGTCTGCCGGGACTGCAAACGGGACCGGCTGGTGGTGGAGAAACCCTTCGGACGG
GACATCGCCTCGGCCCGGACATTGAACCAGCTCCTCTCCGGCATGTTCGTGGAATCCCAGATCTACCGTATCGACCACTT
CCTGGGCAAGGAGACGGTGCAGAACATTCTCGCCTTCCGTTTCGCCAACTCACTGTTCGAGCCGGTCTGGAACCGGCGCT
ACATCGACCATGTGCAGATCACCGTTGCCGAGACCGTGGGGGTGGAGAACCGCGCCAATTTCTTCGAGCAGTCCGGCGCC
TTGCGGGACATGATCCAGAATCACCTGCTGCAGATCCTCTGCCTGGTGGCCATGGAACCTCCCATCTCCTTTGACGCCGA
CGAGGTGCGCAACAAGAAGGTGGACGTGCTGCGCGCCATCCGCCCGATCCTGGCCGATGACGTGCACAAGAGCGCCGTGC
GCGGCCAGTACGCCAGGGGATTCGTGGAGGGGCAGGCCGTGGCCGGTTATCGCGAGGAAAGCGGCGTCTCCCCTCACTCC
TGCACCGAGACCTACGTGGCGCTCAAGCTCCTGATCGACAACTGGCGCTGGCAGGGGGTCCCCTTCTACCTGCGAACCGG
CAAACGCCTTCCGGCAAAGGTCTCCGAAGTCTCCATCATCTTCCGTTCCCCTCCCCACCAGCTCTTCCCCTCCGCCGCGG
TGGACAACTGGCAGCCCAACCGCATCGTGATCAAGATTCAGCCTGAAGAGGGGATCAACACCCGCATCCAGGTCAAGCAA
CCAGGCACCCGCCTGCTGTTGGGGGAGGCGGACATGCGCTTCCGCTATGGCGAGGCCTTCAAGGCGGCAGCACCCGAGGC
CTACGAGACACTGCTCCTGGACGCGATCCGCGGCGATGCCACCCTGTTCATGCGCGCCGACCAGGTGGAATGCGCCTGGA
ACGTGGTCTCACCCATCCTGGCCGCCTGGGAAGCGGTACCTCCCGCGGATTTCCCCGACTACCCGGCCGGCAGCTGGGGG
CCCGAGGCGGCCGACCGCATGATCGCCCGGGGGGGTCACAACTGGCTGCAGCCAGGCATGAAGCGATGA

Upstream 100 bases:

>100_bases
CTCGCGCGGCGAGGCGGACTTCGCCGACCGCCTCTTGTCGGCCATGCGCTACGAATTCGGCGGCCACCATGAAAAGAGCA
CATCAGGGGAGGGATAGATC

Downstream 100 bases:

>100_bases
GCGCCACTGTCCGGCGTTTCAACGACGAAGAATCGCTCAGCCGGGCGGCGGCCGAGATTTTCGCCCTGACCGCGGAACAG
GCGATCGCCTCCCAGGGTCG

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MPSSRKLDPTIIVIFGGGGDLTRRKLIPALHNLMLDNLLPQRCAIIGIGRRSMDDDTFRNHLKSGLEQFSRRGGSTEQPW
DDFGSRISYVSEDVTSKESGAALTRRLNEIDSDWGVRANRIFYLAIPPSMMEPAAAMLQRMGVCRDCKRDRLVVEKPFGR
DIASARTLNQLLSGMFVESQIYRIDHFLGKETVQNILAFRFANSLFEPVWNRRYIDHVQITVAETVGVENRANFFEQSGA
LRDMIQNHLLQILCLVAMEPPISFDADEVRNKKVDVLRAIRPILADDVHKSAVRGQYARGFVEGQAVAGYREESGVSPHS
CTETYVALKLLIDNWRWQGVPFYLRTGKRLPAKVSEVSIIFRSPPHQLFPSAAVDNWQPNRIVIKIQPEEGINTRIQVKQ
PGTRLLLGEADMRFRYGEAFKAAAPEAYETLLLDAIRGDATLFMRADQVECAWNVVSPILAAWEAVPPADFPDYPAGSWG
PEAADRMIARGGHNWLQPGMKR

Sequences:

>Translated_502_residues
MPSSRKLDPTIIVIFGGGGDLTRRKLIPALHNLMLDNLLPQRCAIIGIGRRSMDDDTFRNHLKSGLEQFSRRGGSTEQPW
DDFGSRISYVSEDVTSKESGAALTRRLNEIDSDWGVRANRIFYLAIPPSMMEPAAAMLQRMGVCRDCKRDRLVVEKPFGR
DIASARTLNQLLSGMFVESQIYRIDHFLGKETVQNILAFRFANSLFEPVWNRRYIDHVQITVAETVGVENRANFFEQSGA
LRDMIQNHLLQILCLVAMEPPISFDADEVRNKKVDVLRAIRPILADDVHKSAVRGQYARGFVEGQAVAGYREESGVSPHS
CTETYVALKLLIDNWRWQGVPFYLRTGKRLPAKVSEVSIIFRSPPHQLFPSAAVDNWQPNRIVIKIQPEEGINTRIQVKQ
PGTRLLLGEADMRFRYGEAFKAAAPEAYETLLLDAIRGDATLFMRADQVECAWNVVSPILAAWEAVPPADFPDYPAGSWG
PEAADRMIARGGHNWLQPGMKR
>Mature_501_residues
PSSRKLDPTIIVIFGGGGDLTRRKLIPALHNLMLDNLLPQRCAIIGIGRRSMDDDTFRNHLKSGLEQFSRRGGSTEQPWD
DFGSRISYVSEDVTSKESGAALTRRLNEIDSDWGVRANRIFYLAIPPSMMEPAAAMLQRMGVCRDCKRDRLVVEKPFGRD
IASARTLNQLLSGMFVESQIYRIDHFLGKETVQNILAFRFANSLFEPVWNRRYIDHVQITVAETVGVENRANFFEQSGAL
RDMIQNHLLQILCLVAMEPPISFDADEVRNKKVDVLRAIRPILADDVHKSAVRGQYARGFVEGQAVAGYREESGVSPHSC
TETYVALKLLIDNWRWQGVPFYLRTGKRLPAKVSEVSIIFRSPPHQLFPSAAVDNWQPNRIVIKIQPEEGINTRIQVKQP
GTRLLLGEADMRFRYGEAFKAAAPEAYETLLLDAIRGDATLFMRADQVECAWNVVSPILAAWEAVPPADFPDYPAGSWGP
EAADRMIARGGHNWLQPGMKR

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=499, Percent_Identity=37.4749498997996, Blast_Score=327, Evalue=1e-89,
Organism=Homo sapiens, GI109389365, Length=499, Percent_Identity=37.4749498997996, Blast_Score=327, Evalue=2e-89,
Organism=Homo sapiens, GI52145310, Length=497, Percent_Identity=29.3762575452716, Blast_Score=173, Evalue=3e-43,
Organism=Escherichia coli, GI1788158, Length=493, Percent_Identity=44.0162271805274, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17538218, Length=504, Percent_Identity=35.515873015873, Blast_Score=320, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6324088, Length=496, Percent_Identity=34.2741935483871, Blast_Score=290, Evalue=3e-79,
Organism=Drosophila melanogaster, GI24643350, Length=485, Percent_Identity=37.9381443298969, Blast_Score=312, Evalue=3e-85,
Organism=Drosophila melanogaster, GI24643352, Length=485, Percent_Identity=37.9381443298969, Blast_Score=312, Evalue=4e-85,
Organism=Drosophila melanogaster, GI221513548, Length=492, Percent_Identity=33.3333333333333, Blast_Score=247, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 56532; Mature: 56401

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSRKLDPTIIVIFGGGGDLTRRKLIPALHNLMLDNLLPQRCAIIGIGRRSMDDDTFRN
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHEEECCCCCCCHHHHHH
HLKSGLEQFSRRGGSTEQPWDDFGSRISYVSEDVTSKESGAALTRRLNEIDSDWGVRANR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCE
IFYLAIPPSMMEPAAAMLQRMGVCRDCKRDRLVVEKPFGRDIASARTLNQLLSGMFVESQ
EEEEEECHHHHHHHHHHHHHHCHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
IYRIDHFLGKETVQNILAFRFANSLFEPVWNRRYIDHVQITVAETVGVENRANFFEQSGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEHHHHCCCHHHHHHHHCCH
LRDMIQNHLLQILCLVAMEPPISFDADEVRNKKVDVLRAIRPILADDVHKSAVRGQYARG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
FVEGQAVAGYREESGVSPHSCTETYVALKLLIDNWRWQGVPFYLRTGKRLPAKVSEVSII
HHCCCHHCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHEEEE
FRSPPHQLFPSAAVDNWQPNRIVIKIQPEEGINTRIQVKQPGTRLLLGEADMRFRYGEAF
EECCCHHHCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCEEEECCCCCCEECCCHH
KAAAPEAYETLLLDAIRGDATLFMRADQVECAWNVVSPILAAWEAVPPADFPDYPAGSWG
HHCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PEAADRMIARGGHNWLQPGMKR
HHHHHHHHHHCCCHHCCCCCCC
>Mature Secondary Structure 
PSSRKLDPTIIVIFGGGGDLTRRKLIPALHNLMLDNLLPQRCAIIGIGRRSMDDDTFRN
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHEEECCCCCCCHHHHHH
HLKSGLEQFSRRGGSTEQPWDDFGSRISYVSEDVTSKESGAALTRRLNEIDSDWGVRANR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCE
IFYLAIPPSMMEPAAAMLQRMGVCRDCKRDRLVVEKPFGRDIASARTLNQLLSGMFVESQ
EEEEEECHHHHHHHHHHHHHHCHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
IYRIDHFLGKETVQNILAFRFANSLFEPVWNRRYIDHVQITVAETVGVENRANFFEQSGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEHHHHCCCHHHHHHHHCCH
LRDMIQNHLLQILCLVAMEPPISFDADEVRNKKVDVLRAIRPILADDVHKSAVRGQYARG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
FVEGQAVAGYREESGVSPHSCTETYVALKLLIDNWRWQGVPFYLRTGKRLPAKVSEVSII
HHCCCHHCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHEEEE
FRSPPHQLFPSAAVDNWQPNRIVIKIQPEEGINTRIQVKQPGTRLLLGEADMRFRYGEAF
EECCCHHHCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCEEEECCCCCCEECCCHH
KAAAPEAYETLLLDAIRGDATLFMRADQVECAWNVVSPILAAWEAVPPADFPDYPAGSWG
HHCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PEAADRMIARGGHNWLQPGMKR
HHHHHHHHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1643289 [H]