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The map label for this gene is gluP [H]

Identifier: 118580602

GI number: 118580602

Start: 2359223

End: 2360035

Strand: Reverse

Name: gluP [H]

Synonym: Ppro_2186

Alternate gene names: 118580602

Gene position: 2360035-2359223 (Counterclockwise)

Preceding gene: 118580603

Following gene: 118580595

Centisome position: 58.88

GC content: 63.35

Gene sequence:

>813_bases
ATGGCGCAAAAACCCATACTCTGCCCTCGCTGCCGGACCCTGATCGGCAGCGAGGAACAGACCTGTTCACGCTGCGGGAC
ATCCCGCAACGCTTCCTGGTGGCAGTTCATCAACCGGACGGCCGGGGTATTGGAAGGGGAGTGGCTGGTCAGGGCGCTGA
TCACGCTCAACCTGGTGTATTACTGCGTTTCGCTGCTGGTCAGCTTGTATATCGGCAGGGGAGGCGGGTTTCTCTCTCCC
GATCGGGTGAGTCTGTTGCTGCTGGGGGCTACCGGCAGCGTGCCTCTGGACCAGTTCGGCCGCTTCTGGTCGCTGTTGAG
CGCCAACTACCTGCATGGCGGCATACTGCACCTGCTCTTCAACCTGATGGCGCTGCGACAGATCGGTCCCTGGGTCGTTA
ACGAGTACGGGCCCAGCCGCATGTTCATCATCTATACCCTGGGGGGCATCTTCGGCTTCTGGGTTTCCTGGCAGGCGGGG
GTGGCCTTCACCATCGGCGCGTCCGCCGCCATATGCAGCCTGATCGGCTCCCTGCTGTACTTCGGAAAGAGCAGCGGCGG
GGCCTACGGCGCCTCGGTGTACCGGGAGGTGAGCGGCTGGGTGGTCAGTCTGCTGGTTTTTGGCCTGATCGTGCCGGGGA
TTAACAACTGGGGGCATGGCGGCGGCATCCTCGGCGGGATCCTGTTGGGCATGCTTGTGGGCTACAACGGACGCAGCCGC
GAGACGTCGTGGCACCAGGGGGTGGCGCTGCTCTGTGCAGCAATGACCGCGGCTGTTCTGATCTGGCCACTGTTGACCAT
GCTGCCGGGCTAG

Upstream 100 bases:

>100_bases
GAGGTCGTGCCCCTGATGCGCTCACCTTTTCCGGAACGCTTCCGCCGCGACTGCTCCGGCGGCTTCGAACCATATCCCAC
ACCCGACGAGGGAGCTTGAC

Downstream 100 bases:

>100_bases
TACCCTGTAACGCTTGTTTTTTCGTACCAAACCCTCCCCTTGTCAGGGGAGGGTTAAAGGCTTCCCCCCTGACAAGGGGG
GGCTGAGGAGGGTTGGTTTT

Product: rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MAQKPILCPRCRTLIGSEEQTCSRCGTSRNASWWQFINRTAGVLEGEWLVRALITLNLVYYCVSLLVSLYIGRGGGFLSP
DRVSLLLLGATGSVPLDQFGRFWSLLSANYLHGGILHLLFNLMALRQIGPWVVNEYGPSRMFIIYTLGGIFGFWVSWQAG
VAFTIGASAAICSLIGSLLYFGKSSGGAYGASVYREVSGWVVSLLVFGLIVPGINNWGHGGGILGGILLGMLVGYNGRSR
ETSWHQGVALLCAAMTAAVLIWPLLTMLPG

Sequences:

>Translated_270_residues
MAQKPILCPRCRTLIGSEEQTCSRCGTSRNASWWQFINRTAGVLEGEWLVRALITLNLVYYCVSLLVSLYIGRGGGFLSP
DRVSLLLLGATGSVPLDQFGRFWSLLSANYLHGGILHLLFNLMALRQIGPWVVNEYGPSRMFIIYTLGGIFGFWVSWQAG
VAFTIGASAAICSLIGSLLYFGKSSGGAYGASVYREVSGWVVSLLVFGLIVPGINNWGHGGGILGGILLGMLVGYNGRSR
ETSWHQGVALLCAAMTAAVLIWPLLTMLPG
>Mature_269_residues
AQKPILCPRCRTLIGSEEQTCSRCGTSRNASWWQFINRTAGVLEGEWLVRALITLNLVYYCVSLLVSLYIGRGGGFLSPD
RVSLLLLGATGSVPLDQFGRFWSLLSANYLHGGILHLLFNLMALRQIGPWVVNEYGPSRMFIIYTLGGIFGFWVSWQAGV
AFTIGASAAICSLIGSLLYFGKSSGGAYGASVYREVSGWVVSLLVFGLIVPGINNWGHGGGILGGILLGMLVGYNGRSRE
TSWHQGVALLCAAMTAAVLIWPLLTMLPG

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 29100; Mature: 28968

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKPILCPRCRTLIGSEEQTCSRCGTSRNASWWQFINRTAGVLEGEWLVRALITLNLVY
CCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YCVSLLVSLYIGRGGGFLSPDRVSLLLLGATGSVPLDQFGRFWSLLSANYLHGGILHLLF
HHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLMALRQIGPWVVNEYGPSRMFIIYTLGGIFGFWVSWQAGVAFTIGASAAICSLIGSLLY
HHHHHHHHCCHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHH
FGKSSGGAYGASVYREVSGWVVSLLVFGLIVPGINNWGHGGGILGGILLGMLVGYNGRSR
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
ETSWHQGVALLCAAMTAAVLIWPLLTMLPG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQKPILCPRCRTLIGSEEQTCSRCGTSRNASWWQFINRTAGVLEGEWLVRALITLNLVY
CCCCCCCHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YCVSLLVSLYIGRGGGFLSPDRVSLLLLGATGSVPLDQFGRFWSLLSANYLHGGILHLLF
HHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLMALRQIGPWVVNEYGPSRMFIIYTLGGIFGFWVSWQAGVAFTIGASAAICSLIGSLLY
HHHHHHHHCCHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHH
FGKSSGGAYGASVYREVSGWVVSLLVFGLIVPGINNWGHGGGILGGILLGMLVGYNGRSR
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
ETSWHQGVALLCAAMTAAVLIWPLLTMLPG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]