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The map label for this gene is zraR [H]

Identifier: 118580588

GI number: 118580588

Start: 2344950

End: 2346341

Strand: Direct

Name: zraR [H]

Synonym: Ppro_2172

Alternate gene names: 118580588

Gene position: 2344950-2346341 (Clockwise)

Preceding gene: 118580585

Following gene: 118580589

Centisome position: 58.51

GC content: 51.8

Gene sequence:

>1392_bases
TTGTTATTGTTCCAACCAAACACCGTATCCTCACCATCAAAAAGAAAACAGGGTATCCCGGCGCGCAAGCTACTGTGCGT
GTCGCCTGACGGAGCACGTCAGGCCTCCGCCCAACCCCTTGCCGAAGAAGGCTGGGACATACTGACGGCACCTGACCTGA
AACTGGCCAGGGAGTTGACCAGGCAGCATAAAGACTGTCATGTGGGACTGCTCTTTCTGAAAAGTGGTACGGATGCCTAC
CTGAACCAAATTGAAGAAGTCCTGATGGTGAACAACCAGATTGAATGGATTTCCGTCTTGCCCCCCGAATGCATGCAATC
ACGTGACCTCTGCGCATTCGTTATCAAGAACTCCTACGACTATCACACCCTTCCACTGGATATCCCCCGTTTGCATTTTA
TTCTCGGGCATGCATACGGCAAGGCTCTGCTGAAATGCAAAGTTGCCGGCAGGGAACAGGTTATCGGCCAGAACCAGATG
ATCGGAACAAGCGCGCCAATGCGTGACCTGTATGCAAGAATCATCAAAATACAAAAAGTCGAGTCACCCGTCCTTATCCA
CGGGGAGAGCGGTACGGGCAAGGAGCTTGCGGCGCGTGCGATTCACCAGAATTCATCGCGTTGCCAGGCGCCTTTTGTCG
CGGTGAATTGCGGGGCCTTGCCGACACACCTCATCCAAAGCGAATTATTCGGACACGAGAAAGGGGCTTTTACCGGAGCA
ACCCAGAGAAAGATCGGCCGCATCGAATCGGCGGCGGGTGGAACCATCTTTCTGGACGAGATCGGAGATCTTTCACAGGA
ACTCCAGGTAAACCTTTTGCGGTTCTTGCAGGAAAAGACCATCGAGCGTGTCGGCTCAAACCAGACCATTGAAGTTGACG
TGCGCGTTATAGCCGCTACCCATGTGAACCTGGAAAAAGCCGTGGAACAGGGTGTTTTTCGCGAGGACCTCTATTACCGA
CTGAATGTCCTGCGTCTGGATATTCCACCATTACGCGAACGAGTCGGGGACATAGAAATCCTGGCGCTCACTTTTTTTGA
AAAATTCTCCGAAGAAAAGAACCCCGTGGTCAAGGGATTCAGCCAGCAGACCTTGAATATCATGGCTGAATATGACTGGC
CGGGTAATGTTAGAGAAATGATAAATCGAATACGAAGGGCGATGGTGATGAGCGAGAACCGGCTGATCACACCCGCTGAC
CTGGAGCTGGACAATCTGGTGGTCTTAAACAAATCGCTATCGCTGGATGATGCGCGAGTGCTGGCGGAAACCGAGATAAT
CCAGCATTCCCTCATACAGAACAACAAGAATGTCTCCAAGACCGCGCGCGATCTCGGCGTATCGCGCGTTACGCTGTACA
GGTTGATAAACAAACTGAATATCATCGTCTAG

Upstream 100 bases:

>100_bases
GCCCACACATCATACGGAATGAGTCCACTATGCCTTAGGGATGAAATGAGAAGCACACGACACCGCTTTTGAACCATCAG
TTTGAACGGGGGGGTGAGCT

Downstream 100 bases:

>100_bases
GAGCGTCTGGCATTGCAATCAACGCCTCAATCGGGGTTACGACAATGAGAAAAGAATCTCAGCTGCTTGTCCTTCTCGCT
ACTCTCGGCATTACACCTCT

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MLLFQPNTVSSPSKRKQGIPARKLLCVSPDGARQASAQPLAEEGWDILTAPDLKLARELTRQHKDCHVGLLFLKSGTDAY
LNQIEEVLMVNNQIEWISVLPPECMQSRDLCAFVIKNSYDYHTLPLDIPRLHFILGHAYGKALLKCKVAGREQVIGQNQM
IGTSAPMRDLYARIIKIQKVESPVLIHGESGTGKELAARAIHQNSSRCQAPFVAVNCGALPTHLIQSELFGHEKGAFTGA
TQRKIGRIESAAGGTIFLDEIGDLSQELQVNLLRFLQEKTIERVGSNQTIEVDVRVIAATHVNLEKAVEQGVFREDLYYR
LNVLRLDIPPLRERVGDIEILALTFFEKFSEEKNPVVKGFSQQTLNIMAEYDWPGNVREMINRIRRAMVMSENRLITPAD
LELDNLVVLNKSLSLDDARVLAETEIIQHSLIQNNKNVSKTARDLGVSRVTLYRLINKLNIIV

Sequences:

>Translated_463_residues
MLLFQPNTVSSPSKRKQGIPARKLLCVSPDGARQASAQPLAEEGWDILTAPDLKLARELTRQHKDCHVGLLFLKSGTDAY
LNQIEEVLMVNNQIEWISVLPPECMQSRDLCAFVIKNSYDYHTLPLDIPRLHFILGHAYGKALLKCKVAGREQVIGQNQM
IGTSAPMRDLYARIIKIQKVESPVLIHGESGTGKELAARAIHQNSSRCQAPFVAVNCGALPTHLIQSELFGHEKGAFTGA
TQRKIGRIESAAGGTIFLDEIGDLSQELQVNLLRFLQEKTIERVGSNQTIEVDVRVIAATHVNLEKAVEQGVFREDLYYR
LNVLRLDIPPLRERVGDIEILALTFFEKFSEEKNPVVKGFSQQTLNIMAEYDWPGNVREMINRIRRAMVMSENRLITPAD
LELDNLVVLNKSLSLDDARVLAETEIIQHSLIQNNKNVSKTARDLGVSRVTLYRLINKLNIIV
>Mature_463_residues
MLLFQPNTVSSPSKRKQGIPARKLLCVSPDGARQASAQPLAEEGWDILTAPDLKLARELTRQHKDCHVGLLFLKSGTDAY
LNQIEEVLMVNNQIEWISVLPPECMQSRDLCAFVIKNSYDYHTLPLDIPRLHFILGHAYGKALLKCKVAGREQVIGQNQM
IGTSAPMRDLYARIIKIQKVESPVLIHGESGTGKELAARAIHQNSSRCQAPFVAVNCGALPTHLIQSELFGHEKGAFTGA
TQRKIGRIESAAGGTIFLDEIGDLSQELQVNLLRFLQEKTIERVGSNQTIEVDVRVIAATHVNLEKAVEQGVFREDLYYR
LNVLRLDIPPLRERVGDIEILALTFFEKFSEEKNPVVKGFSQQTLNIMAEYDWPGNVREMINRIRRAMVMSENRLITPAD
LELDNLVVLNKSLSLDDARVLAETEIIQHSLIQNNKNVSKTARDLGVSRVTLYRLINKLNIIV

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=344, Percent_Identity=45.0581395348837, Blast_Score=284, Evalue=7e-78,
Organism=Escherichia coli, GI1788550, Length=355, Percent_Identity=43.0985915492958, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI1788905, Length=352, Percent_Identity=39.4886363636364, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI87082117, Length=237, Percent_Identity=51.4767932489451, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1790299, Length=242, Percent_Identity=48.3471074380165, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789087, Length=311, Percent_Identity=42.443729903537, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1786524, Length=311, Percent_Identity=42.443729903537, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=40.1869158878505, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI87082152, Length=328, Percent_Identity=40.8536585365854, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI1787583, Length=308, Percent_Identity=37.3376623376623, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87081872, Length=326, Percent_Identity=36.1963190184049, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1789828, Length=227, Percent_Identity=36.1233480176211, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI87081858, Length=287, Percent_Identity=32.404181184669, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51925; Mature: 51925

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLFQPNTVSSPSKRKQGIPARKLLCVSPDGARQASAQPLAEEGWDILTAPDLKLARELT
CEEECCCCCCCCHHHHCCCCHHHEEEECCCCCCCCCCCCHHHCCCCEEECCCHHHHHHHH
RQHKDCHVGLLFLKSGTDAYLNQIEEVLMVNNQIEWISVLPPECMQSRDLCAFVIKNSYD
HHCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCHHHHCCCCEEEEEEECCCC
YHTLPLDIPRLHFILGHAYGKALLKCKVAGREQVIGQNQMIGTSAPMRDLYARIIKIQKV
CEECCCCCHHHHHHHHHHHHHHHEEEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
ESPVLIHGESGTGKELAARAIHQNSSRCQAPFVAVNCGALPTHLIQSELFGHEKGAFTGA
CCCEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCH
TQRKIGRIESAAGGTIFLDEIGDLSQELQVNLLRFLQEKTIERVGSNQTIEVDVRVIAAT
HHHHHHHHHCCCCCEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
HVNLEKAVEQGVFREDLYYRLNVLRLDIPPLRERVGDIEILALTFFEKFSEEKNPVVKGF
CCCHHHHHHCCCHHHHHHHEEEEEEECCCHHHHHCCCEEEEHHHHHHHHCCCCCHHHCCC
SQQTLNIMAEYDWPGNVREMINRIRRAMVMSENRLITPADLELDNLVVLNKSLSLDDARV
CHHEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHH
LAETEIIQHSLIQNNKNVSKTARDLGVSRVTLYRLINKLNIIV
HHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLFQPNTVSSPSKRKQGIPARKLLCVSPDGARQASAQPLAEEGWDILTAPDLKLARELT
CEEECCCCCCCCHHHHCCCCHHHEEEECCCCCCCCCCCCHHHCCCCEEECCCHHHHHHHH
RQHKDCHVGLLFLKSGTDAYLNQIEEVLMVNNQIEWISVLPPECMQSRDLCAFVIKNSYD
HHCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCHHHHCCCCEEEEEEECCCC
YHTLPLDIPRLHFILGHAYGKALLKCKVAGREQVIGQNQMIGTSAPMRDLYARIIKIQKV
CEECCCCCHHHHHHHHHHHHHHHEEEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
ESPVLIHGESGTGKELAARAIHQNSSRCQAPFVAVNCGALPTHLIQSELFGHEKGAFTGA
CCCEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCH
TQRKIGRIESAAGGTIFLDEIGDLSQELQVNLLRFLQEKTIERVGSNQTIEVDVRVIAAT
HHHHHHHHHCCCCCEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
HVNLEKAVEQGVFREDLYYRLNVLRLDIPPLRERVGDIEILALTFFEKFSEEKNPVVKGF
CCCHHHHHHCCCHHHHHHHEEEEEEECCCHHHHHCCCEEEEHHHHHHHHCCCCCHHHCCC
SQQTLNIMAEYDWPGNVREMINRIRRAMVMSENRLITPADLELDNLVVLNKSLSLDDARV
CHHEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHH
LAETEIIQHSLIQNNKNVSKTARDLGVSRVTLYRLINKLNIIV
HHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]