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The map label for this gene is yegD [H]

Identifier: 118580561

GI number: 118580561

Start: 2301275

End: 2302546

Strand: Reverse

Name: yegD [H]

Synonym: Ppro_2145

Alternate gene names: 118580561

Gene position: 2302546-2301275 (Counterclockwise)

Preceding gene: 118580562

Following gene: 118580560

Centisome position: 57.45

GC content: 61.79

Gene sequence:

>1272_bases
ATGCAGATTGTTTTTGGCATCGATTTCGGGACAACCAACTCGGCGCTCTCGGTGTATCGCAACGGCGCGGTGGAAATGGT
TGCCCTGGATGGCGCCGGAACGGCCGCTGCGCTGATGCGTTCGGTGCTCTATTTCAACGAGGAAAATGAGATTTTCGCCG
GCCAGGAGGCCATTCGCCAGTATGTGGACGACGGGGCAGGGGGGCGTTTCATGCAATCCATCAAGACCTTTCTGCCCAAC
AGCAGCTTTGACGGTACCGAGGTGTTTGGCAGGCGCTATGCCATCGAGGACCTGGTGGCAATCATCCTCAAGAGGATCAA
AGCCCAGGGGGAGAACCATGTGGGGCGGTCCGTGGACAGCGTGGTGCTGGGGCGGCCGGTTCTGTTCTCCTCGGATCCGG
CCAAGGACAGTCTGGCCCAGCGGCGCCTGGAAAAGGCGGCCCGCAAGGCCGGCTTCTCCAGGATCTGGTTCCAGTACGAA
CCGGTGGCGGCGGCGCTGACTTTCGAGGAGACCCTGCGATCGGGGGAGGAACGGGTCGTGTTCATCGGCGACTTCGGCGG
AGGCACCTCCGACTTCTCGGTCATCCGTGTGCGGGGTGGCGACTCCGGACGCTCCGACCGGCGCGGGGATGTGCTCTCTC
TGGGCGGGGTCTACATTGCCGGCGACTCCTTCGATTCCCAGATCATGTGGGACCGGGTGGCCCGGCATTTCGGACGGTAC
GCCCGATACAAGACTTTGGGCAAGGACGAGTGGGTCTCCGTGCCCAGGAGCATCACCCACACCCTCTGCCAGTGGCATCG
CATCCCGCTCCTGCGGGCACGGGCCACCAGGGAGCATATCAGGGTCATCAAGGGAAGCACCGATGATCGCCGGGCCATCG
AAAATCTGGAGAACATTATCAGCGACAACTACGGCTTTTTCCTGTTCCAGGCCATCGAGAAGGCCAAGTGCGAGCTCTCC
GGCCAGGAGCGGGCAATGATCCGTTTTTCGGAGCGCGACCTGTGTATCAACGAAGAGATCGACAGGGACGGGTTCGAGGC
GATCAACGGGGAGAACTTCCAGCGCATAGCCGACTGCGTCGACGAGGTGGTTTCCGGTTCAGGGCTTGCCCCGGAGCAGA
TGGATACGGTGTTTCTGACCGGCGGCACGTCGCGCATTCCCCGTATCCAGTCCCTGTTCGCCCAGCGCTTCGGCAAGGAA
AAACTGGAGCAGCGCAACGCGTTTACCAGCGTTGCCCATGGTCTCGGCTCCAGCGTTCCGTTGTTTGCCTGA

Upstream 100 bases:

>100_bases
CACCACAGCACAATTCCCTCTGGATCGATCCCTGTCCGCACGCCGTAGTGGCGCTGTCTGTCGCGGATTTTTTCGTCTGT
GGGAAACGGAGGCTTTGTAC

Downstream 100 bases:

>100_bases
TACGGAGATTTGTGCCTCGGACCGGAAGGGAAAAACGGCCTTTGGGAGTGGCTCCCCGGCGTATGAACAATTGAAACCTC
CTGCGATATCACGTATGCTG

Product: molecular chaperone-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MQIVFGIDFGTTNSALSVYRNGAVEMVALDGAGTAAALMRSVLYFNEENEIFAGQEAIRQYVDDGAGGRFMQSIKTFLPN
SSFDGTEVFGRRYAIEDLVAIILKRIKAQGENHVGRSVDSVVLGRPVLFSSDPAKDSLAQRRLEKAARKAGFSRIWFQYE
PVAAALTFEETLRSGEERVVFIGDFGGGTSDFSVIRVRGGDSGRSDRRGDVLSLGGVYIAGDSFDSQIMWDRVARHFGRY
ARYKTLGKDEWVSVPRSITHTLCQWHRIPLLRARATREHIRVIKGSTDDRRAIENLENIISDNYGFFLFQAIEKAKCELS
GQERAMIRFSERDLCINEEIDRDGFEAINGENFQRIADCVDEVVSGSGLAPEQMDTVFLTGGTSRIPRIQSLFAQRFGKE
KLEQRNAFTSVAHGLGSSVPLFA

Sequences:

>Translated_423_residues
MQIVFGIDFGTTNSALSVYRNGAVEMVALDGAGTAAALMRSVLYFNEENEIFAGQEAIRQYVDDGAGGRFMQSIKTFLPN
SSFDGTEVFGRRYAIEDLVAIILKRIKAQGENHVGRSVDSVVLGRPVLFSSDPAKDSLAQRRLEKAARKAGFSRIWFQYE
PVAAALTFEETLRSGEERVVFIGDFGGGTSDFSVIRVRGGDSGRSDRRGDVLSLGGVYIAGDSFDSQIMWDRVARHFGRY
ARYKTLGKDEWVSVPRSITHTLCQWHRIPLLRARATREHIRVIKGSTDDRRAIENLENIISDNYGFFLFQAIEKAKCELS
GQERAMIRFSERDLCINEEIDRDGFEAINGENFQRIADCVDEVVSGSGLAPEQMDTVFLTGGTSRIPRIQSLFAQRFGKE
KLEQRNAFTSVAHGLGSSVPLFA
>Mature_423_residues
MQIVFGIDFGTTNSALSVYRNGAVEMVALDGAGTAAALMRSVLYFNEENEIFAGQEAIRQYVDDGAGGRFMQSIKTFLPN
SSFDGTEVFGRRYAIEDLVAIILKRIKAQGENHVGRSVDSVVLGRPVLFSSDPAKDSLAQRRLEKAARKAGFSRIWFQYE
PVAAALTFEETLRSGEERVVFIGDFGGGTSDFSVIRVRGGDSGRSDRRGDVLSLGGVYIAGDSFDSQIMWDRVARHFGRY
ARYKTLGKDEWVSVPRSITHTLCQWHRIPLLRARATREHIRVIKGSTDDRRAIENLENIISDNYGFFLFQAIEKAKCELS
GQERAMIRFSERDLCINEEIDRDGFEAINGENFQRIADCVDEVVSGSGLAPEQMDTVFLTGGTSRIPRIQSLFAQRFGKE
KLEQRNAFTSVAHGLGSSVPLFA

Specific function: Unknown

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Homo sapiens, GI16507237, Length=441, Percent_Identity=27.6643990929705, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI24234686, Length=435, Percent_Identity=25.0574712643678, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI5729877, Length=435, Percent_Identity=25.0574712643678, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI24234688, Length=440, Percent_Identity=24.3181818181818, Blast_Score=83, Evalue=6e-16,
Organism=Escherichia coli, GI87082035, Length=459, Percent_Identity=25.7080610021786, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786196, Length=251, Percent_Identity=29.0836653386454, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1786870, Length=197, Percent_Identity=27.9187817258883, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788875, Length=259, Percent_Identity=29.7297297297297, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17568549, Length=442, Percent_Identity=26.4705882352941, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17534771, Length=447, Percent_Identity=25.9507829977629, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17541098, Length=435, Percent_Identity=25.0574712643678, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562024, Length=438, Percent_Identity=23.7442922374429, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17507981, Length=424, Percent_Identity=25.9433962264151, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322505, Length=438, Percent_Identity=24.8858447488584, Blast_Score=90, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6319396, Length=440, Percent_Identity=23.6363636363636, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320805, Length=438, Percent_Identity=24.2009132420091, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24653595, Length=440, Percent_Identity=23.8636363636364, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571678, Length=440, Percent_Identity=25, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647034, Length=438, Percent_Identity=25.1141552511416, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647038, Length=438, Percent_Identity=25.1141552511416, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647036, Length=438, Percent_Identity=25.1141552511416, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17737967, Length=438, Percent_Identity=25.1141552511416, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571721, Length=438, Percent_Identity=25.1141552511416, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571719, Length=438, Percent_Identity=25.1141552511416, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646324, Length=440, Percent_Identity=25, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646322, Length=440, Percent_Identity=25, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646318, Length=440, Percent_Identity=25, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646137, Length=440, Percent_Identity=25, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646135, Length=440, Percent_Identity=25, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17738165, Length=439, Percent_Identity=24.1457858769932, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17647515, Length=436, Percent_Identity=24.5412844036697, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641406, Length=248, Percent_Identity=29.0322580645161, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641408, Length=248, Percent_Identity=29.0322580645161, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641402, Length=248, Percent_Identity=29.0322580645161, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641404, Length=248, Percent_Identity=29.0322580645161, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 47064; Mature: 47064

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS01036 HSP70_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIVFGIDFGTTNSALSVYRNGAVEMVALDGAGTAAALMRSVLYFNEENEIFAGQEAIRQ
CEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEECCHHHHHH
YVDDGAGGRFMQSIKTFLPNSSFDGTEVFGRRYAIEDLVAIILKRIKAQGENHVGRSVDS
HHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VVLGRPVLFSSDPAKDSLAQRRLEKAARKAGFSRIWFQYEPVAAALTFEETLRSGEERVV
HHHCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCEEE
FIGDFGGGTSDFSVIRVRGGDSGRSDRRGDVLSLGGVYIAGDSFDSQIMWDRVARHFGRY
EEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCEEEECCCCCHHHHHHHHHHHHHHH
ARYKTLGKDEWVSVPRSITHTLCQWHRIPLLRARATREHIRVIKGSTDDRRAIENLENII
HHHHHCCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SDNYGFFLFQAIEKAKCELSGQERAMIRFSERDLCINEEIDRDGFEAINGENFQRIADCV
CCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCHHHHHHHH
DEVVSGSGLAPEQMDTVFLTGGTSRIPRIQSLFAQRFGKEKLEQRNAFTSVAHGLGSSVP
HHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
LFA
CCC
>Mature Secondary Structure
MQIVFGIDFGTTNSALSVYRNGAVEMVALDGAGTAAALMRSVLYFNEENEIFAGQEAIRQ
CEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEECCHHHHHH
YVDDGAGGRFMQSIKTFLPNSSFDGTEVFGRRYAIEDLVAIILKRIKAQGENHVGRSVDS
HHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VVLGRPVLFSSDPAKDSLAQRRLEKAARKAGFSRIWFQYEPVAAALTFEETLRSGEERVV
HHHCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCEEE
FIGDFGGGTSDFSVIRVRGGDSGRSDRRGDVLSLGGVYIAGDSFDSQIMWDRVARHFGRY
EEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCEEEECCCCCHHHHHHHHHHHHHHH
ARYKTLGKDEWVSVPRSITHTLCQWHRIPLLRARATREHIRVIKGSTDDRRAIENLENII
HHHHHCCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SDNYGFFLFQAIEKAKCELSGQERAMIRFSERDLCINEEIDRDGFEAINGENFQRIADCV
CCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCHHHHHHHH
DEVVSGSGLAPEQMDTVFLTGGTSRIPRIQSLFAQRFGKEKLEQRNAFTSVAHGLGSSVP
HHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
LFA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7940673; 7984428 [H]