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The map label for this gene is 118580488

Identifier: 118580488

GI number: 118580488

Start: 2225798

End: 2227279

Strand: Reverse

Name: 118580488

Synonym: Ppro_2072

Alternate gene names: NA

Gene position: 2227279-2225798 (Counterclockwise)

Preceding gene: 118580501

Following gene: 118580487

Centisome position: 55.57

GC content: 59.11

Gene sequence:

>1482_bases
ATGGGAAGCCGAGCCAAGAAACAGCACCTCCACGCGGATGGCGGGAAACCTATGATCACATGGATACGGAAGTTATTGGG
AAAAGAACCGTCGTTCGAACAGTCGCCACCGATGCCCCGGGAACCCCAGGACCATTCGTCCCATGACTCAGCTCAACAGA
CCGGTGTTGCCGGGCCTGAGGCAGATCTCCCGGTCCCCGAGGAGTGGCGGCCGCTGCTGACTGAAATGGAGCAGAGCAGC
GGGCACTTCTTTGTCACCGGCCAGGCAGGAACCGGGAAATCGACCCTGATCGGACTGTTCCGCCGCCTGACGGGGAAAAA
TGTCGTCGTGGTGGCTCCCACCGGACTCGCCGCCATCACCGCCCAGGGCGTTACCATCCATTCACTGACCCGGTTCCCGC
CGACGGTGATAACGAGGGACAGCGTCGGGGAAATCACCGAAAAGCATCTGATACGGGCAATAGATACCATCATCGTTGAC
GAGGTAAGCCAGGTTCGCTGCGACCTGCTGGACGGCCTGGACCATTTCATGCGCAGAAACGGCAGGGACAAAGAGTTGCC
ATTCGGAGGCGTTCAGGTCATCCTGGTGGGTGACCCCTGCCAGCTCCCTCCAGTGGTGAGCGATGGGGAACGACAATCCC
TGGAGCGGGCCGGATACCCGGGCCCCTTTTATTTCTGGAACTCCAGCGTCTACGGGGAAATCAACCCGCGCAGGCTGGAG
TTGAAAACACGGTTCCGCCAGGCCGAGCAGGACTTTCTCGATCTGCTGGGTTGCATCCGCACAAACGATGTCCACACCGG
AAAACTCGACCTCCTGCAGCAGTGCATGGCAGACACTGATTTCGACCCCTTTTTCCGTCCGTTCCATACCATGCTGACTT
GGCGCGGTGATGAAGCCGGATATTACAACAACAGGGAGTTCTACCGGCTTCCCGGCCCCCGGCAGGAGTACCGGGCGAAA
CGCACTGGCTCGGCGCTCAACATCAACAACCCTGAGTACAATTTCCCCTGCGAGGAAAACCTCCTGCTGCGGGTGGGGGC
TCGCGTCATCTGCTGCCGGGACATCAGTGCAGAGCTTCTGAACGGAACCATGGGAACGGTCGTGGAACTGGAAGATGAGG
CGGTCTTGATTCGAGCCGACGACGGCAGGAGTCTGCGGGTACTCCCTGCGGTATGGGAGCTGATCACGTATTCCTACAGT
CGGGAAACGGGGAAGATAGAGTCGACGGTTACCGGAACCATCGAACAGATTCCGCTGCGTCATGCCTGGGCGCTCAGCAT
CCACAAAGCCCAGGGGGTGACCCTGGATCAGGTGCACATCGATCTCTCGGACGCGGCATTCCCCCCCGGACAGGCGTACA
TTGCCCTCAGCCGCTGCCGCTCCTTCGCGGGGACCAAGCTCAAAACCAAGTTTTTCAATCTTGATCCAGGGGATGTCATG
GTGGACGGTGATATAGTCGAGTTCATGTCATCATTGTCTTGA

Upstream 100 bases:

>100_bases
GCAAGGGGTTCTGGTGCACGATGGGGAGGGGATGGCGCCCAATAAAAAATTGACCCCTTCTTTCGCCTTGTGTAGATTGG
CTACGGCCCAGAGGATTCAG

Downstream 100 bases:

>100_bases
GGGAATGGCGGGGAGGAATAAATGTCGGCGATGAACTTTAACACGGCAAACCAGACGTTTCGTCAGTTATTGGGAAACGG
CCTCGTCTATCGTGTGCCTC

Product: TPR domain-containing protein

Products: NA

Alternate protein names: Helicase; TPR Domain Protein; TPR Domain-Containing Protein; ATPase; Exonuclease V Subunit Alpha; 5-3' DNA Helicase; Helicase-Related Protein; Aaa ATPase; Glycosysltransferase; Hrdc Domain Protein; Helicase-Family Protein; Helicase Protein; HRDC Domain Protein; RecD-Like Exodeoxyribonuclease V Alpha Chain; RRM3/PIF1 Helicase-Like Protein; ATP-Dependent ExoDNAse Alpha Subunit; DNA Helicase AAA ATPase; DNA Helicase/AAA ATPase; Helicase RecD/TraA Family

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MGSRAKKQHLHADGGKPMITWIRKLLGKEPSFEQSPPMPREPQDHSSHDSAQQTGVAGPEADLPVPEEWRPLLTEMEQSS
GHFFVTGQAGTGKSTLIGLFRRLTGKNVVVVAPTGLAAITAQGVTIHSLTRFPPTVITRDSVGEITEKHLIRAIDTIIVD
EVSQVRCDLLDGLDHFMRRNGRDKELPFGGVQVILVGDPCQLPPVVSDGERQSLERAGYPGPFYFWNSSVYGEINPRRLE
LKTRFRQAEQDFLDLLGCIRTNDVHTGKLDLLQQCMADTDFDPFFRPFHTMLTWRGDEAGYYNNREFYRLPGPRQEYRAK
RTGSALNINNPEYNFPCEENLLLRVGARVICCRDISAELLNGTMGTVVELEDEAVLIRADDGRSLRVLPAVWELITYSYS
RETGKIESTVTGTIEQIPLRHAWALSIHKAQGVTLDQVHIDLSDAAFPPGQAYIALSRCRSFAGTKLKTKFFNLDPGDVM
VDGDIVEFMSSLS

Sequences:

>Translated_493_residues
MGSRAKKQHLHADGGKPMITWIRKLLGKEPSFEQSPPMPREPQDHSSHDSAQQTGVAGPEADLPVPEEWRPLLTEMEQSS
GHFFVTGQAGTGKSTLIGLFRRLTGKNVVVVAPTGLAAITAQGVTIHSLTRFPPTVITRDSVGEITEKHLIRAIDTIIVD
EVSQVRCDLLDGLDHFMRRNGRDKELPFGGVQVILVGDPCQLPPVVSDGERQSLERAGYPGPFYFWNSSVYGEINPRRLE
LKTRFRQAEQDFLDLLGCIRTNDVHTGKLDLLQQCMADTDFDPFFRPFHTMLTWRGDEAGYYNNREFYRLPGPRQEYRAK
RTGSALNINNPEYNFPCEENLLLRVGARVICCRDISAELLNGTMGTVVELEDEAVLIRADDGRSLRVLPAVWELITYSYS
RETGKIESTVTGTIEQIPLRHAWALSIHKAQGVTLDQVHIDLSDAAFPPGQAYIALSRCRSFAGTKLKTKFFNLDPGDVM
VDGDIVEFMSSLS
>Mature_492_residues
GSRAKKQHLHADGGKPMITWIRKLLGKEPSFEQSPPMPREPQDHSSHDSAQQTGVAGPEADLPVPEEWRPLLTEMEQSSG
HFFVTGQAGTGKSTLIGLFRRLTGKNVVVVAPTGLAAITAQGVTIHSLTRFPPTVITRDSVGEITEKHLIRAIDTIIVDE
VSQVRCDLLDGLDHFMRRNGRDKELPFGGVQVILVGDPCQLPPVVSDGERQSLERAGYPGPFYFWNSSVYGEINPRRLEL
KTRFRQAEQDFLDLLGCIRTNDVHTGKLDLLQQCMADTDFDPFFRPFHTMLTWRGDEAGYYNNREFYRLPGPRQEYRAKR
TGSALNINNPEYNFPCEENLLLRVGARVICCRDISAELLNGTMGTVVELEDEAVLIRADDGRSLRVLPAVWELITYSYSR
ETGKIESTVTGTIEQIPLRHAWALSIHKAQGVTLDQVHIDLSDAAFPPGQAYIALSRCRSFAGTKLKTKFFNLDPGDVMV
DGDIVEFMSSLS

Specific function: Unknown

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI82546872, Length=426, Percent_Identity=31.4553990610329, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI25143421, Length=439, Percent_Identity=26.879271070615, Blast_Score=144, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6323579, Length=317, Percent_Identity=32.1766561514196, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6321820, Length=347, Percent_Identity=27.0893371757925, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI19920652, Length=462, Percent_Identity=27.4891774891775, Blast_Score=142, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 55037; Mature: 54906

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSRAKKQHLHADGGKPMITWIRKLLGKEPSFEQSPPMPREPQDHSSHDSAQQTGVAGPE
CCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCC
ADLPVPEEWRPLLTEMEQSSGHFFVTGQAGTGKSTLIGLFRRLTGKNVVVVAPTGLAAIT
CCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEE
AQGVTIHSLTRFPPTVITRDSVGEITEKHLIRAIDTIIVDEVSQVRCDLLDGLDHFMRRN
ECCEEEEEHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRDKELPFGGVQVILVGDPCQLPPVVSDGERQSLERAGYPGPFYFWNSSVYGEINPRRLE
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCEEEECCCCCEEH
LKTRFRQAEQDFLDLLGCIRTNDVHTGKLDLLQQCMADTDFDPFFRPFHTMLTWRGDEAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCC
YYNNREFYRLPGPRQEYRAKRTGSALNINNPEYNFPCEENLLLRVGARVICCRDISAELL
CCCCCEEEECCCCHHHHHHHHCCCEEECCCCCCCCCCCCCHHEECCCEEEEECCHHHHHH
NGTMGTVVELEDEAVLIRADDGRSLRVLPAVWELITYSYSRETGKIESTVTGTIEQIPLR
CCCCCEEEEECCCEEEEEECCCCCEEHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHCCCC
HAWALSIHKAQGVTLDQVHIDLSDAAFPPGQAYIALSRCRSFAGTKLKTKFFNLDPGDVM
CEEEEEEECCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEE
VDGDIVEFMSSLS
ECCHHHHHHHHCC
>Mature Secondary Structure 
GSRAKKQHLHADGGKPMITWIRKLLGKEPSFEQSPPMPREPQDHSSHDSAQQTGVAGPE
CCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCC
ADLPVPEEWRPLLTEMEQSSGHFFVTGQAGTGKSTLIGLFRRLTGKNVVVVAPTGLAAIT
CCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEE
AQGVTIHSLTRFPPTVITRDSVGEITEKHLIRAIDTIIVDEVSQVRCDLLDGLDHFMRRN
ECCEEEEEHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRDKELPFGGVQVILVGDPCQLPPVVSDGERQSLERAGYPGPFYFWNSSVYGEINPRRLE
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCEEEECCCCCEEH
LKTRFRQAEQDFLDLLGCIRTNDVHTGKLDLLQQCMADTDFDPFFRPFHTMLTWRGDEAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCC
YYNNREFYRLPGPRQEYRAKRTGSALNINNPEYNFPCEENLLLRVGARVICCRDISAELL
CCCCCEEEECCCCHHHHHHHHCCCEEECCCCCCCCCCCCCHHEECCCEEEEECCHHHHHH
NGTMGTVVELEDEAVLIRADDGRSLRVLPAVWELITYSYSRETGKIESTVTGTIEQIPLR
CCCCCEEEEECCCEEEEEECCCCCEEHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHCCCC
HAWALSIHKAQGVTLDQVHIDLSDAAFPPGQAYIALSRCRSFAGTKLKTKFFNLDPGDVM
CEEEEEEECCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEE
VDGDIVEFMSSLS
ECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA