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The map label for this gene is luxQ [H]

Identifier: 118580477

GI number: 118580477

Start: 2209293

End: 2211509

Strand: Direct

Name: luxQ [H]

Synonym: Ppro_2061

Alternate gene names: 118580477

Gene position: 2209293-2211509 (Clockwise)

Preceding gene: 118580476

Following gene: 118580478

Centisome position: 55.12

GC content: 61.21

Gene sequence:

>2217_bases
ATGGATACTTGCCACACACTTCACGACATGCGCACGGCGCTGACCGAACTGGAAGAGGCGCTGTCAGGCCTCGACACCCC
GGACGTGACCATTCGACAACTGGAAGAGGCGCTGCAACTGATGCGCAGGGCTCGGGCAGAGCTCCAGCCCACAGTAACCT
GCACGGAAGCGCCTTTCAGGGCGCCGAAGGATGGCGGTATGGAGCGGTGCTCCACATACGACCGGGAATACCGCACCCTG
CTGCCGGATGGCAAGGTGCGTTGGATCAACACCCAGGGTACGACCATCCCCAATCCCCAGGGGCATGGGCAGCCCATGAC
CGGCATCAGCATCGATGTCTCCGACCGCCAGCGGGCGGATGATTCGCTGCGCCGCAGCGAAGAACGCTACCGTTCCCTGG
TGGAGCTTTCCCCCGACGCCGTCTTCATCAACCTCAAAAACCGCATCGTGTTCGTCAACCCGGCGGCGGTGCGCCTCTTC
GGCGCCGCATCGGCCCAGCAGCTCCTGGGCAAGAGCCCCTTCGACCTGATGCACCCCGACTGCCACGACGTGATCCGTGC
GCGCATTGAACAGCAACGCGCGGGCCAGATCGCACAGCTGATAGAGGAAAAGGTCCTGCGCCTGGACAGCAGCGTTATTG
ATGTGGAGGTTTCCGCGGCCCCGCTCAACACGGAAGAGGGAACCGCGTTCCAGGTCATCCTGCGCGATATCAGCGACCGC
AAAAGAGCTGAGCAGGCCCTGGCTACGGCCAAGGAGCAGGCCGAGGCGGCCAGCCGCGCCAAGAGCGAATTTCTGGCCAA
CATGAGCCATGAAATCCGCAGTCCCATGAACGGCATCATGGGCATGGCACAGCTCATGGAGTACACCGAACTCACCGACG
AGCAGCGGGAATACCTGAATGTGATCAGGTCATCCTCCCATGGCCTGCTCTCCCTGATCAACAACATACTCGATCTCTCC
AAGATAGAAGCGGGCAAAATCGAACTAGAACGGAGTGATTTCAGCCTGCGGGCCAGCATCGACGACATCGTCAAAGCCCA
CCTCTCCCAGATTCACGACAAAGGGCTCACCATACGCACCGACATCCCGGCCGCCGCGCCGGACACCCTGATCGGCGACC
AACTGCGCCTGAAACAGATCCTGCTCAACCTTCTGGGCAATGCCATCAAGTTCACCTGCCGGGGAGGCATCGGCATCTCG
GTCGCTGTCAGCGAGCGCCGCGACGAAAGAGTCCGGCTGAGAATCGACGTAACGGACACCGGCATCGGCATCCCCACCGA
TGCCATGGAGAGAATCTTCAAGCCGTTTACCCAGGCCGACTCTTCCACCACGCGGCAGTACGGCGGAACCGGTCTCGGCC
TCTCCATCTGCAGCCGCCTGGCGGAGTTGATGGATGGCAAGATCACAGTGGAAAGCAGGGAGGGCAGCGGCAGCACCTTC
TCGGTCCATCTCCCCTTCGCGGTCAGTGGAACCGCCATGGAGCGCCGAAGTGGCGGCAGCAGCCAACGGGCGCGCGCCAG
CTGGGATGGTCCGGCGTTGCACATACTGCTGGTGGATGATTATGAGATGAATCTGCTGGCTGTCACACGGCTGCTGCAGC
GCCACGGTCACACCGTGGTTCCGGCTCGCGATGGCGCGGAGGCCGTGCAAAAATGGGAGCAGGAAGCATTCGACGCGATC
CTGATGGATATACAGATGCCGGTCATGGACGGCATGGAGGCTACGCGGACCATCCGGCGCAGGGAAGCGGGGACCGGCAG
GCACACGCCGGTTATCGCGCTTACCGGGCGTGCCCTCCAGGAGGAGCAGGACGAGATCATGGGCCAGGGTTTCGACGGTC
ATATCTCCAAGCCGATCCAGTTGGGCATGCTGTTCCAGGAGCTGCGCAGGTGCCTGCCGCATGCAACCAAGGAGGAGGAA
ACGATCCTTCCGTCAAAGGAGACTCCCTCGACCGTTGTCGACAGGCAACTACTGGCAAGGCTGCTGGGCAAGATGGAGCT
CCTGCTGTCCAGCCACAATCTGGCGACCATCGATTTGCTCTCCGATATTATGAAAACAGCGCCGCCTACCGCTGCGCTGA
AGATCTTCCGGGACCATCTCAAACGCTTCAATTTTGACGGGGCATTGGGCTGCCTGGACGAGCTGTACCGCGAGTTCGAT
ATTACACGTGAGACGGGAAACTTCCATGGAGAGACAGAGAATCCTGATCGTCGATGA

Upstream 100 bases:

>100_bases
CAGGCTGTTACATGAGGCATGTTCGGGACGATTTGTAATGTGGCGGCTCGGTAGTACACTTGTAGCGTTCGTTCTCATGA
GACGCCGCCGGAGAGTCACC

Downstream 100 bases:

>100_bases
CACCCCGGAGAACCTCCAGTTGCTCTACCGCACTCTCAGGGACGAGTATGACCTCTACGGAGCCACCAATGGCAGGGAAG
CGCTCATGATCGCAGCGGCG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 738; Mature: 738

Protein sequence:

>738_residues
MDTCHTLHDMRTALTELEEALSGLDTPDVTIRQLEEALQLMRRARAELQPTVTCTEAPFRAPKDGGMERCSTYDREYRTL
LPDGKVRWINTQGTTIPNPQGHGQPMTGISIDVSDRQRADDSLRRSEERYRSLVELSPDAVFINLKNRIVFVNPAAVRLF
GAASAQQLLGKSPFDLMHPDCHDVIRARIEQQRAGQIAQLIEEKVLRLDSSVIDVEVSAAPLNTEEGTAFQVILRDISDR
KRAEQALATAKEQAEAASRAKSEFLANMSHEIRSPMNGIMGMAQLMEYTELTDEQREYLNVIRSSSHGLLSLINNILDLS
KIEAGKIELERSDFSLRASIDDIVKAHLSQIHDKGLTIRTDIPAAAPDTLIGDQLRLKQILLNLLGNAIKFTCRGGIGIS
VAVSERRDERVRLRIDVTDTGIGIPTDAMERIFKPFTQADSSTTRQYGGTGLGLSICSRLAELMDGKITVESREGSGSTF
SVHLPFAVSGTAMERRSGGSSQRARASWDGPALHILLVDDYEMNLLAVTRLLQRHGHTVVPARDGAEAVQKWEQEAFDAI
LMDIQMPVMDGMEATRTIRRREAGTGRHTPVIALTGRALQEEQDEIMGQGFDGHISKPIQLGMLFQELRRCLPHATKEEE
TILPSKETPSTVVDRQLLARLLGKMELLLSSHNLATIDLLSDIMKTAPPTAALKIFRDHLKRFNFDGALGCLDELYREFD
ITRETGNFHGETENPDRR

Sequences:

>Translated_738_residues
MDTCHTLHDMRTALTELEEALSGLDTPDVTIRQLEEALQLMRRARAELQPTVTCTEAPFRAPKDGGMERCSTYDREYRTL
LPDGKVRWINTQGTTIPNPQGHGQPMTGISIDVSDRQRADDSLRRSEERYRSLVELSPDAVFINLKNRIVFVNPAAVRLF
GAASAQQLLGKSPFDLMHPDCHDVIRARIEQQRAGQIAQLIEEKVLRLDSSVIDVEVSAAPLNTEEGTAFQVILRDISDR
KRAEQALATAKEQAEAASRAKSEFLANMSHEIRSPMNGIMGMAQLMEYTELTDEQREYLNVIRSSSHGLLSLINNILDLS
KIEAGKIELERSDFSLRASIDDIVKAHLSQIHDKGLTIRTDIPAAAPDTLIGDQLRLKQILLNLLGNAIKFTCRGGIGIS
VAVSERRDERVRLRIDVTDTGIGIPTDAMERIFKPFTQADSSTTRQYGGTGLGLSICSRLAELMDGKITVESREGSGSTF
SVHLPFAVSGTAMERRSGGSSQRARASWDGPALHILLVDDYEMNLLAVTRLLQRHGHTVVPARDGAEAVQKWEQEAFDAI
LMDIQMPVMDGMEATRTIRRREAGTGRHTPVIALTGRALQEEQDEIMGQGFDGHISKPIQLGMLFQELRRCLPHATKEEE
TILPSKETPSTVVDRQLLARLLGKMELLLSSHNLATIDLLSDIMKTAPPTAALKIFRDHLKRFNFDGALGCLDELYREFD
ITRETGNFHGETENPDRR
>Mature_738_residues
MDTCHTLHDMRTALTELEEALSGLDTPDVTIRQLEEALQLMRRARAELQPTVTCTEAPFRAPKDGGMERCSTYDREYRTL
LPDGKVRWINTQGTTIPNPQGHGQPMTGISIDVSDRQRADDSLRRSEERYRSLVELSPDAVFINLKNRIVFVNPAAVRLF
GAASAQQLLGKSPFDLMHPDCHDVIRARIEQQRAGQIAQLIEEKVLRLDSSVIDVEVSAAPLNTEEGTAFQVILRDISDR
KRAEQALATAKEQAEAASRAKSEFLANMSHEIRSPMNGIMGMAQLMEYTELTDEQREYLNVIRSSSHGLLSLINNILDLS
KIEAGKIELERSDFSLRASIDDIVKAHLSQIHDKGLTIRTDIPAAAPDTLIGDQLRLKQILLNLLGNAIKFTCRGGIGIS
VAVSERRDERVRLRIDVTDTGIGIPTDAMERIFKPFTQADSSTTRQYGGTGLGLSICSRLAELMDGKITVESREGSGSTF
SVHLPFAVSGTAMERRSGGSSQRARASWDGPALHILLVDDYEMNLLAVTRLLQRHGHTVVPARDGAEAVQKWEQEAFDAI
LMDIQMPVMDGMEATRTIRRREAGTGRHTPVIALTGRALQEEQDEIMGQGFDGHISKPIQLGMLFQELRRCLPHATKEEE
TILPSKETPSTVVDRQLLARLLGKMELLLSSHNLATIDLLSDIMKTAPPTAALKIFRDHLKRFNFDGALGCLDELYREFD
ITRETGNFHGETENPDRR

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=552, Percent_Identity=30.4347826086957, Blast_Score=248, Evalue=9e-67,
Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=48.3193277310924, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1788713, Length=506, Percent_Identity=28.0632411067194, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI145693157, Length=323, Percent_Identity=35.2941176470588, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI87081816, Length=396, Percent_Identity=32.5757575757576, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=30.3643724696356, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788549, Length=263, Percent_Identity=28.1368821292776, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1788393, Length=237, Percent_Identity=27.0042194092827, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=30.3418803418803, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1786600, Length=363, Percent_Identity=26.4462809917355, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=29.2576419213974, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1790300, Length=247, Percent_Identity=29.9595141700405, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1790861, Length=251, Percent_Identity=27.0916334661355, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1787894, Length=271, Percent_Identity=26.5682656826568, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=24.8908296943231, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788545, Length=253, Percent_Identity=24.901185770751, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786783, Length=237, Percent_Identity=23.6286919831224, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=228, Percent_Identity=25.4385964912281, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=74, Percent_Identity=51.3513513513513, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6322000, Length=178, Percent_Identity=26.4044943820225, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82122; Mature: 82122

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTCHTLHDMRTALTELEEALSGLDTPDVTIRQLEEALQLMRRARAELQPTVTCTEAPFR
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
APKDGGMERCSTYDREYRTLLPDGKVRWINTQGTTIPNPQGHGQPMTGISIDVSDRQRAD
CCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCHHHHH
DSLRRSEERYRSLVELSPDAVFINLKNRIVFVNPAAVRLFGAASAQQLLGKSPFDLMHPD
HHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECHHHHHHHCCHHHHHHHCCCCCHHCCCC
CHDVIRARIEQQRAGQIAQLIEEKVLRLDSSVIDVEVSAAPLNTEEGTAFQVILRDISDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHH
KRAEQALATAKEQAEAASRAKSEFLANMSHEIRSPMNGIMGMAQLMEYTELTDEQREYLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRSSSHGLLSLINNILDLSKIEAGKIELERSDFSLRASIDDIVKAHLSQIHDKGLTIRT
HHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEECCHHHHHHHHHHHHHHCCCEEEE
DIPAAAPDTLIGDQLRLKQILLNLLGNAIKFTCRGGIGISVAVSERRDERVRLRIDVTDT
CCCCCCCCCCCCHHHHHHHHHHHHHCHHEEEEECCCCEEEEEECCCCCCEEEEEEEEECC
GIGIPTDAMERIFKPFTQADSSTTRQYGGTGLGLSICSRLAELMDGKITVESREGSGSTF
CCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCEE
SVHLPFAVSGTAMERRSGGSSQRARASWDGPALHILLVDDYEMNLLAVTRLLQRHGHTVV
EEEECEEECCCHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEE
PARDGAEAVQKWEQEAFDAILMDIQMPVMDGMEATRTIRRREAGTGRHTPVIALTGRALQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEECCHHHH
EEQDEIMGQGFDGHISKPIQLGMLFQELRRCLPHATKEEETILPSKETPSTVVDRQLLAR
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LLGKMELLLSSHNLATIDLLSDIMKTAPPTAALKIFRDHLKRFNFDGALGCLDELYREFD
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
ITRETGNFHGETENPDRR
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDTCHTLHDMRTALTELEEALSGLDTPDVTIRQLEEALQLMRRARAELQPTVTCTEAPFR
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
APKDGGMERCSTYDREYRTLLPDGKVRWINTQGTTIPNPQGHGQPMTGISIDVSDRQRAD
CCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCHHHHH
DSLRRSEERYRSLVELSPDAVFINLKNRIVFVNPAAVRLFGAASAQQLLGKSPFDLMHPD
HHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECHHHHHHHCCHHHHHHHCCCCCHHCCCC
CHDVIRARIEQQRAGQIAQLIEEKVLRLDSSVIDVEVSAAPLNTEEGTAFQVILRDISDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHH
KRAEQALATAKEQAEAASRAKSEFLANMSHEIRSPMNGIMGMAQLMEYTELTDEQREYLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRSSSHGLLSLINNILDLSKIEAGKIELERSDFSLRASIDDIVKAHLSQIHDKGLTIRT
HHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEECCHHHHHHHHHHHHHHCCCEEEE
DIPAAAPDTLIGDQLRLKQILLNLLGNAIKFTCRGGIGISVAVSERRDERVRLRIDVTDT
CCCCCCCCCCCCHHHHHHHHHHHHHCHHEEEEECCCCEEEEEECCCCCCEEEEEEEEECC
GIGIPTDAMERIFKPFTQADSSTTRQYGGTGLGLSICSRLAELMDGKITVESREGSGSTF
CCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCEE
SVHLPFAVSGTAMERRSGGSSQRARASWDGPALHILLVDDYEMNLLAVTRLLQRHGHTVV
EEEECEEECCCHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEE
PARDGAEAVQKWEQEAFDAILMDIQMPVMDGMEATRTIRRREAGTGRHTPVIALTGRALQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEECCHHHH
EEQDEIMGQGFDGHISKPIQLGMLFQELRRCLPHATKEEETILPSKETPSTVVDRQLLAR
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LLGKMELLLSSHNLATIDLLSDIMKTAPPTAALKIFRDHLKRFNFDGALGCLDELYREFD
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
ITRETGNFHGETENPDRR
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA