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The map label for this gene is tsf

Identifier: 118580461

GI number: 118580461

Start: 2194908

End: 2195846

Strand: Direct

Name: tsf

Synonym: Ppro_2045

Alternate gene names: 118580461

Gene position: 2194908-2195846 (Clockwise)

Preceding gene: 118580460

Following gene: 118580462

Centisome position: 54.76

GC content: 59.32

Gene sequence:

>939_bases
ATGGCAATTACAGCTGCCCAAATCAATGAACTGAGAAAAGCTACCGGAGCCGGTATGCTCGACTGCAAGAAAGCCCTGGA
ACAGAACGACGGCGATTTCGAGAAATCCGTCGACTACCTGCGTACCAAGGGACTGGCCGCGGCAGCCAAGAAATCCAGCC
GCGCCGCCACCGAGGGAATGGTGGCAGCCTTCGTGTCCGACGACCTGAAGAGCGGCGTGCTGCTGGAAATCAACAGCGAA
ACCGATTTTGTCGCCAAAAACGATCTCTTCAAGGCTTTTGTGAACAATATCGGCCAGCACATCCTGTCCACCTCCCCCGC
CGACCGCGACGCCATGCTGGCGCAGCCCTACAGCGGTGATCCCTCCAAGACCGTACAGAGCTACCTGAACGAATCCATTT
CGGTCATTGGCGAGAACATCCAGATCCGCCGCTTCTCCCGCTTCGATGTCCAGGGCGATGGCTGCATCGGTGCCTACATC
CACGCCGGCGGCAAGATTGGCGTCATGGTGCAGGTGGAGAGCCCGGCTGTCACCTCCGCCAACCAGGAGACCATCACCAC
CCTGGTGAAGGATGTCGCCATGCACTCGGCGGCAGCCGCGCCCCGTTACGTCACCCGCGAGCAGGTACCTGCCGACGTCC
TGGAGCGCGAGAAGGACATCTACCGCGCCAAGGCACGGGAGACCGGCAAACCGGATAACATCATCGAAAAGATCATTGTC
GGCCAGATCAATAAGTTCTACGGTGACATCTGCCTCAACGAGCAGGTCTACGTAAAGGATACCGACAAGACCATTCCCCA
GGTACTCAAGGAAGCCTCAGCCGCGGCGGGCGGAACCATCGGCATCAGTCGATTCGAGCGCTTCGTGCTTGGCGAGGGTC
TGGAGAAGAAGGAATCGGATTTTGCCGCCGAGGTGGCGGCAGCGGCCGGCCTCAAATAG

Upstream 100 bases:

>100_bases
GCGCGGTCGGGAACGGTCCAGCGGACCGTCTCTCGCCGCGCCTTCCACGGCGTCGTCACAGGAATCAGATACAGCACATT
TCGGAAGGAGCTCCCCACCC

Downstream 100 bases:

>100_bases
CAGCCACAGCCGGCCGGAAATGGCCGGCTTTTTTTTATTCAGTACACACGGAACGGGAGAGAGCATGAGCAGGCCGAAAT
TCACCAGGGTATTGCTGAAG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MAITAAQINELRKATGAGMLDCKKALEQNDGDFEKSVDYLRTKGLAAAAKKSSRAATEGMVAAFVSDDLKSGVLLEINSE
TDFVAKNDLFKAFVNNIGQHILSTSPADRDAMLAQPYSGDPSKTVQSYLNESISVIGENIQIRRFSRFDVQGDGCIGAYI
HAGGKIGVMVQVESPAVTSANQETITTLVKDVAMHSAAAAPRYVTREQVPADVLEREKDIYRAKARETGKPDNIIEKIIV
GQINKFYGDICLNEQVYVKDTDKTIPQVLKEASAAAGGTIGISRFERFVLGEGLEKKESDFAAEVAAAAGLK

Sequences:

>Translated_312_residues
MAITAAQINELRKATGAGMLDCKKALEQNDGDFEKSVDYLRTKGLAAAAKKSSRAATEGMVAAFVSDDLKSGVLLEINSE
TDFVAKNDLFKAFVNNIGQHILSTSPADRDAMLAQPYSGDPSKTVQSYLNESISVIGENIQIRRFSRFDVQGDGCIGAYI
HAGGKIGVMVQVESPAVTSANQETITTLVKDVAMHSAAAAPRYVTREQVPADVLEREKDIYRAKARETGKPDNIIEKIIV
GQINKFYGDICLNEQVYVKDTDKTIPQVLKEASAAAGGTIGISRFERFVLGEGLEKKESDFAAEVAAAAGLK
>Mature_311_residues
AITAAQINELRKATGAGMLDCKKALEQNDGDFEKSVDYLRTKGLAAAAKKSSRAATEGMVAAFVSDDLKSGVLLEINSET
DFVAKNDLFKAFVNNIGQHILSTSPADRDAMLAQPYSGDPSKTVQSYLNESISVIGENIQIRRFSRFDVQGDGCIGAYIH
AGGKIGVMVQVESPAVTSANQETITTLVKDVAMHSAAAAPRYVTREQVPADVLEREKDIYRAKARETGKPDNIIEKIIVG
QINKFYGDICLNEQVYVKDTDKTIPQVLKEASAAAGGTIGISRFERFVLGEGLEKKESDFAAEVAAAAGLK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=222, Percent_Identity=25.2252252252252, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1786366, Length=308, Percent_Identity=39.2857142857143, Blast_Score=193, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17561440, Length=163, Percent_Identity=30.6748466257669, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19921466, Length=308, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_PELPD (A1AQN3)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901711.1
- ProteinModelPortal:   A1AQN3
- SMR:   A1AQN3
- STRING:   A1AQN3
- GeneID:   4574242
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2045
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   A1AQN3
- ProtClustDB:   PRK09377
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 33557; Mature: 33426

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITAAQINELRKATGAGMLDCKKALEQNDGDFEKSVDYLRTKGLAAAAKKSSRAATEGM
CCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VAAFVSDDLKSGVLLEINSETDFVAKNDLFKAFVNNIGQHILSTSPADRDAMLAQPYSGD
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCC
PSKTVQSYLNESISVIGENIQIRRFSRFDVQGDGCIGAYIHAGGKIGVMVQVESPAVTSA
HHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEECCCEEEEEEEECCCCCCCC
NQETITTLVKDVAMHSAAAAPRYVTREQVPADVLEREKDIYRAKARETGKPDNIIEKIIV
CHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GQINKFYGDICLNEQVYVKDTDKTIPQVLKEASAAAGGTIGISRFERFVLGEGLEKKESD
HHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHH
FAAEVAAAAGLK
HHHHHHHHCCCC
>Mature Secondary Structure 
AITAAQINELRKATGAGMLDCKKALEQNDGDFEKSVDYLRTKGLAAAAKKSSRAATEGM
CCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VAAFVSDDLKSGVLLEINSETDFVAKNDLFKAFVNNIGQHILSTSPADRDAMLAQPYSGD
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCC
PSKTVQSYLNESISVIGENIQIRRFSRFDVQGDGCIGAYIHAGGKIGVMVQVESPAVTSA
HHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEECCCEEEEEEEECCCCCCCC
NQETITTLVKDVAMHSAAAAPRYVTREQVPADVLEREKDIYRAKARETGKPDNIIEKIIV
CHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GQINKFYGDICLNEQVYVKDTDKTIPQVLKEASAAAGGTIGISRFERFVLGEGLEKKESD
HHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHH
FAAEVAAAAGLK
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA