Click here to switch to the map view.

The map label for this gene is aroC

Identifier: 118580444

GI number: 118580444

Start: 2177073

End: 2178254

Strand: Reverse

Name: aroC

Synonym: Ppro_2028

Alternate gene names: 118580444

Gene position: 2178254-2177073 (Counterclockwise)

Preceding gene: 118580445

Following gene: 118580443

Centisome position: 54.35

GC content: 63.62

Gene sequence:

>1182_bases
ATGCTTCGTTATCTGACAGCAGGGGAATCCCACGGACCACAGTTGACCGCGATTATCGAGGGGATGCCGGCCGGCGTTCC
GCTTCTGGCCGAGGATATCAACCGCGAGCTGGCCCGGCGCCAGCAGGGCTACGGCCGTGGCGACCGGATGAAGATCGAGA
AAGACCAGGTGGAGATACTCTCCGGGGTGCGTTGGGGAGAGACGCTGGCATCACCGTTAACCCTGGTGGTGAAAAACCGC
GACTGGGAAAACTGGAGTACGAAGATGTCGTCGCTTCCGGAGTTTCGCGACGAATCACAGGCTGTCACACGTCCCCGTCC
AGGCCATGCCGACCTGGGCGGCGCCCTCAAGTACGGTCACCGGGACCTGCGCAACATCCTGGAACGCTCCAGTGCCCGCG
AGACTGCCGTGCGTGTTGCCGTGGGAGCTGCTGCCAAGGCCCTGCTGCGGCTCTTCGGCATCAGGGTGGGTGGGGTTGTC
CGCGAAGTGGGTGGTGTCGTAGCCACCGACCCCGCTGCCTCCTTTGAATACATCTGGGCCAGCGCCGGACAGTCGCCATT
GTTCTGCTGTGACGGGGCTGCCGAGCAGGAGATGAAACGACTGATCGATGACGCCAAGGGGAGCGGCGATACCCTGGGTG
GGGTGGTGGAGGTGCAGGTGATCGGCGTTCCGCCCGGCCTGGGGAGCCATGTCCAGTGGGACCGCAAGCTGGATGCGCGA
CTGGCCATGGCGCTGATGAGCATTCAGGCCATCAAGGGGGTCGAGGTGGGCATCGGTTTTGAGACGGCCCGACGCCCCGG
TTCCCAGGTGCACGATGAGATATTCCGCGATGCCGCACGCACCGGAGCCGATTCAGGCGGCGCCTATTACCGCACGTCCA
ACAATGCCGGCGGCATCGAGGGGGGCATGTCCAACGGCGAGGCGATCATCCTCAGGGCTGCCATGAAACCGATCCCCACC
CTCTATAAGCCGCTCCGCTCGGTTGACATGCTGACCCATGAGCCGTTCCAGGCGGCGGTTGAGCGCTCCGATACCTGTGC
CGTTCCTGCCGCGCTGGTGGTGGCCGAGGCGGTTGTTGCCGTTGAGATCGCCAATGCCTTTCTCGAGAAGTTCGGCGGCG
ATTCCGTCCAGGAAATCAGGCGCAATTACCAGGGGTATTGCGAACGGATTCGCACCCTCTGA

Upstream 100 bases:

>100_bases
CCTGTCGTGAAACGGCAAAAGTCTTTTGCCTTGCCGAGCGCCCGGCATAAATGCTATTTTGGCCGGGATTCTTCATATTC
ATGGAGGTTTTTTTATTTCT

Downstream 100 bases:

>100_bases
GCTCCCCGGCAGCCGTGAGCCCAGGTTTGTGGCCGCGCCCGCCAGGCGGTATGCTATGGTGACCGCAGCGAGGGGAGTCG
GGGTGCACTTTATGTTCAGA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MLRYLTAGESHGPQLTAIIEGMPAGVPLLAEDINRELARRQQGYGRGDRMKIEKDQVEILSGVRWGETLASPLTLVVKNR
DWENWSTKMSSLPEFRDESQAVTRPRPGHADLGGALKYGHRDLRNILERSSARETAVRVAVGAAAKALLRLFGIRVGGVV
REVGGVVATDPAASFEYIWASAGQSPLFCCDGAAEQEMKRLIDDAKGSGDTLGGVVEVQVIGVPPGLGSHVQWDRKLDAR
LAMALMSIQAIKGVEVGIGFETARRPGSQVHDEIFRDAARTGADSGGAYYRTSNNAGGIEGGMSNGEAIILRAAMKPIPT
LYKPLRSVDMLTHEPFQAAVERSDTCAVPAALVVAEAVVAVEIANAFLEKFGGDSVQEIRRNYQGYCERIRTL

Sequences:

>Translated_393_residues
MLRYLTAGESHGPQLTAIIEGMPAGVPLLAEDINRELARRQQGYGRGDRMKIEKDQVEILSGVRWGETLASPLTLVVKNR
DWENWSTKMSSLPEFRDESQAVTRPRPGHADLGGALKYGHRDLRNILERSSARETAVRVAVGAAAKALLRLFGIRVGGVV
REVGGVVATDPAASFEYIWASAGQSPLFCCDGAAEQEMKRLIDDAKGSGDTLGGVVEVQVIGVPPGLGSHVQWDRKLDAR
LAMALMSIQAIKGVEVGIGFETARRPGSQVHDEIFRDAARTGADSGGAYYRTSNNAGGIEGGMSNGEAIILRAAMKPIPT
LYKPLRSVDMLTHEPFQAAVERSDTCAVPAALVVAEAVVAVEIANAFLEKFGGDSVQEIRRNYQGYCERIRTL
>Mature_393_residues
MLRYLTAGESHGPQLTAIIEGMPAGVPLLAEDINRELARRQQGYGRGDRMKIEKDQVEILSGVRWGETLASPLTLVVKNR
DWENWSTKMSSLPEFRDESQAVTRPRPGHADLGGALKYGHRDLRNILERSSARETAVRVAVGAAAKALLRLFGIRVGGVV
REVGGVVATDPAASFEYIWASAGQSPLFCCDGAAEQEMKRLIDDAKGSGDTLGGVVEVQVIGVPPGLGSHVQWDRKLDAR
LAMALMSIQAIKGVEVGIGFETARRPGSQVHDEIFRDAARTGADSGGAYYRTSNNAGGIEGGMSNGEAIILRAAMKPIPT
LYKPLRSVDMLTHEPFQAAVERSDTCAVPAALVVAEAVVAVEIANAFLEKFGGDSVQEIRRNYQGYCERIRTL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=371, Percent_Identity=38.544474393531, Blast_Score=189, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6321290, Length=380, Percent_Identity=33.1578947368421, Blast_Score=175, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_PELPD (A1AQL6)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901694.1
- ProteinModelPortal:   A1AQL6
- SMR:   A1AQL6
- STRING:   A1AQL6
- GeneID:   4574697
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2028
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42381; Mature: 42381

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRYLTAGESHGPQLTAIIEGMPAGVPLLAEDINRELARRQQGYGRGDRMKIEKDQVEIL
CCEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHH
SGVRWGETLASPLTLVVKNRDWENWSTKMSSLPEFRDESQAVTRPRPGHADLGGALKYGH
HCCHHHHHHHCCEEEEEECCCCCHHHHHHHCCCHHHCCCHHCCCCCCCCCCCCHHHHHHH
RDLRNILERSSARETAVRVAVGAAAKALLRLFGIRVGGVVREVGGVVATDPAASFEYIWA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHH
SAGQSPLFCCDGAAEQEMKRLIDDAKGSGDTLGGVVEVQVIGVPPGLGSHVQWDRKLDAR
CCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHH
LAMALMSIQAIKGVEVGIGFETARRPGSQVHDEIFRDAARTGADSGGAYYRTSNNAGGIE
HHHHHHHHHHHCCCEECCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCC
GGMSNGEAIILRAAMKPIPTLYKPLRSVDMLTHEPFQAAVERSDTCAVPAALVVAEAVVA
CCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHH
VEIANAFLEKFGGDSVQEIRRNYQGYCERIRTL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLRYLTAGESHGPQLTAIIEGMPAGVPLLAEDINRELARRQQGYGRGDRMKIEKDQVEIL
CCEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHH
SGVRWGETLASPLTLVVKNRDWENWSTKMSSLPEFRDESQAVTRPRPGHADLGGALKYGH
HCCHHHHHHHCCEEEEEECCCCCHHHHHHHCCCHHHCCCHHCCCCCCCCCCCCHHHHHHH
RDLRNILERSSARETAVRVAVGAAAKALLRLFGIRVGGVVREVGGVVATDPAASFEYIWA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHH
SAGQSPLFCCDGAAEQEMKRLIDDAKGSGDTLGGVVEVQVIGVPPGLGSHVQWDRKLDAR
CCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHH
LAMALMSIQAIKGVEVGIGFETARRPGSQVHDEIFRDAARTGADSGGAYYRTSNNAGGIE
HHHHHHHHHHHCCCEECCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCC
GGMSNGEAIILRAAMKPIPTLYKPLRSVDMLTHEPFQAAVERSDTCAVPAALVVAEAVVA
CCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHH
VEIANAFLEKFGGDSVQEIRRNYQGYCERIRTL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA