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The map label for this gene is aroB

Identifier: 118580443

GI number: 118580443

Start: 2175809

End: 2176888

Strand: Reverse

Name: aroB

Synonym: Ppro_2027

Alternate gene names: 118580443

Gene position: 2176888-2175809 (Counterclockwise)

Preceding gene: 118580444

Following gene: 118580442

Centisome position: 54.31

GC content: 62.31

Gene sequence:

>1080_bases
GTGAGTGTGCTGACCGTCAACCTGGGAGAAAACAGTTACGATATTCTGATCGACGGCGGTACGCTCCCGTCGCTGGGGCG
ACACTGCCTCGAACGGGGGCTTTCCGGGCGCGTGGCGGTGATCAGCAACCCTGCCGTGGCGGAGTTGTACGCCGAGCAGG
TGCGGGCATCGCTTGTCGAGTCAGGCAATCAGGTTACCCTGATCCTGATTCCCGAAGGAGAGGAACACAAGAACGCGGCG
ACCTTGAACCTCGTCTATGATCAGCTGATCCAGGCGGGTCTGGATCGCAACTCCTACATCGTGGCCCTCGGGGGCGGTGT
CGTGGGAGACCTGGCCGGTTTCGCCGCCGCGACCTTCCTGCGCGGCATCCCCTTTGTGCAGGTTCCCACAACCCTGCTGG
CGCAGGTCGACAGCAGCGTTGGCGGCAAGACAGCCATCGACCATCCGCGGGGCAAGAATCTGATCGGCGCCTTCTATCAG
CCGCGCCTCGTACTGATCGACGTGGAGACGCTTACCACGCTTCCGCAGCGCGAGTTTCGCGCCGGCCTGGCCGAGGTGAT
CAAATACGGCGTAGCCATGGACCTGGCCTTCTATGAACTCCTGGAACGGGACAGCGGCAGGATTCTGGAGATGGATGCCG
ACTGCCTGGAGCGCATCGTGTTGCGCTGCTGTGAACTGAAGGCGCGGGTTGTGGAGCAAGACGAGAAGGAGAGCGGACTA
CGCGCCATCCTCAACTACGGCCATACCCTGGGCCATGCCATTGAAACCCTGGCCGGTTACGGCACCCTGGTGCATGGCGA
GGCGGTTGCCATCGGCATGGTGCTTGCCGCCCGGATCAGTCTGGCCGGCGGATACTGCAGCGAGGGGGATGTTTCCCGGA
TCGTCGCTCTCCTGGGGCGTTTTGGTCTCCCGTGCATCCCTCCCCGGATCGACCAAGGCCGTTTGGCGGAGACCTTGCTG
ACGGACAAGAAGAGTCGCAGCGGCATCATCAGATTTATCTGCAATCGCGGCATCGGCGACTGTGTCGTGGTTAACTTGAC
CGCGGAGCAACTGCTCACCCTGAGTGGACTGGAGGTCTGA

Upstream 100 bases:

>100_bases
GCACTTTATGTTCAGAGGGAATTATTGGAATTGACATGGACAACGTTTCCGTGGAAGATGTTGCGCCAAAGATTATGAAG
GTTTTAAAGGGGTTGCCTGC

Downstream 100 bases:

>100_bases
ATCATGCAACATGAACGTGCATCATTCTGGGCTGATATCAAGAACTACGAGGAGCATCTGGCGCAGAACCCCGATTCCTA
TCTCTTCTCCCGGTTGTCGG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSVLTVNLGENSYDILIDGGTLPSLGRHCLERGLSGRVAVISNPAVAELYAEQVRASLVESGNQVTLILIPEGEEHKNAA
TLNLVYDQLIQAGLDRNSYIVALGGGVVGDLAGFAAATFLRGIPFVQVPTTLLAQVDSSVGGKTAIDHPRGKNLIGAFYQ
PRLVLIDVETLTTLPQREFRAGLAEVIKYGVAMDLAFYELLERDSGRILEMDADCLERIVLRCCELKARVVEQDEKESGL
RAILNYGHTLGHAIETLAGYGTLVHGEAVAIGMVLAARISLAGGYCSEGDVSRIVALLGRFGLPCIPPRIDQGRLAETLL
TDKKSRSGIIRFICNRGIGDCVVVNLTAEQLLTLSGLEV

Sequences:

>Translated_359_residues
MSVLTVNLGENSYDILIDGGTLPSLGRHCLERGLSGRVAVISNPAVAELYAEQVRASLVESGNQVTLILIPEGEEHKNAA
TLNLVYDQLIQAGLDRNSYIVALGGGVVGDLAGFAAATFLRGIPFVQVPTTLLAQVDSSVGGKTAIDHPRGKNLIGAFYQ
PRLVLIDVETLTTLPQREFRAGLAEVIKYGVAMDLAFYELLERDSGRILEMDADCLERIVLRCCELKARVVEQDEKESGL
RAILNYGHTLGHAIETLAGYGTLVHGEAVAIGMVLAARISLAGGYCSEGDVSRIVALLGRFGLPCIPPRIDQGRLAETLL
TDKKSRSGIIRFICNRGIGDCVVVNLTAEQLLTLSGLEV
>Mature_358_residues
SVLTVNLGENSYDILIDGGTLPSLGRHCLERGLSGRVAVISNPAVAELYAEQVRASLVESGNQVTLILIPEGEEHKNAAT
LNLVYDQLIQAGLDRNSYIVALGGGVVGDLAGFAAATFLRGIPFVQVPTTLLAQVDSSVGGKTAIDHPRGKNLIGAFYQP
RLVLIDVETLTTLPQREFRAGLAEVIKYGVAMDLAFYELLERDSGRILEMDADCLERIVLRCCELKARVVEQDEKESGLR
AILNYGHTLGHAIETLAGYGTLVHGEAVAIGMVLAARISLAGGYCSEGDVSRIVALLGRFGLPCIPPRIDQGRLAETLLT
DKKSRSGIIRFICNRGIGDCVVVNLTAEQLLTLSGLEV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=354, Percent_Identity=48.0225988700565, Blast_Score=296, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6320332, Length=384, Percent_Identity=36.4583333333333, Blast_Score=209, Evalue=8e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_PELPD (A1AQL5)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901693.1
- ProteinModelPortal:   A1AQL5
- SMR:   A1AQL5
- STRING:   A1AQL5
- GeneID:   4574696
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2027
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- PhylomeDB:   A1AQL5
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 38422; Mature: 38291

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLTVNLGENSYDILIDGGTLPSLGRHCLERGLSGRVAVISNPAVAELYAEQVRASLVE
CEEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHH
SGNQVTLILIPEGEEHKNAATLNLVYDQLIQAGLDRNSYIVALGGGVVGDLAGFAAATFL
CCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIPFVQVPTTLLAQVDSSVGGKTAIDHPRGKNLIGAFYQPRLVLIDVETLTTLPQREFR
HCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCEEEEEEHHHHHCCCHHHHH
AGLAEVIKYGVAMDLAFYELLERDSGRILEMDADCLERIVLRCCELKARVVEQDEKESGL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RAILNYGHTLGHAIETLAGYGTLVHGEAVAIGMVLAARISLAGGYCSEGDVSRIVALLGR
HHHHHHCHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
FGLPCIPPRIDQGRLAETLLTDKKSRSGIIRFICNRGIGDCVVVNLTAEQLLTLSGLEV
CCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEECHHHHHHHCCCCC
>Mature Secondary Structure 
SVLTVNLGENSYDILIDGGTLPSLGRHCLERGLSGRVAVISNPAVAELYAEQVRASLVE
EEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHH
SGNQVTLILIPEGEEHKNAATLNLVYDQLIQAGLDRNSYIVALGGGVVGDLAGFAAATFL
CCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIPFVQVPTTLLAQVDSSVGGKTAIDHPRGKNLIGAFYQPRLVLIDVETLTTLPQREFR
HCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCEEEEEEHHHHHCCCHHHHH
AGLAEVIKYGVAMDLAFYELLERDSGRILEMDADCLERIVLRCCELKARVVEQDEKESGL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RAILNYGHTLGHAIETLAGYGTLVHGEAVAIGMVLAARISLAGGYCSEGDVSRIVALLGR
HHHHHHCHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
FGLPCIPPRIDQGRLAETLLTDKKSRSGIIRFICNRGIGDCVVVNLTAEQLLTLSGLEV
CCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEECHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA