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The map label for this gene is yqhT [H]

Identifier: 118580440

GI number: 118580440

Start: 2173337

End: 2174416

Strand: Reverse

Name: yqhT [H]

Synonym: Ppro_2024

Alternate gene names: 118580440

Gene position: 2174416-2173337 (Counterclockwise)

Preceding gene: 118580441

Following gene: 118580439

Centisome position: 54.25

GC content: 60.65

Gene sequence:

>1080_bases
ATGGATTTACCTATGCTACACATCAGGCGCGCCAGACTGGAGCGCTTTTTCACTGCCCATGACCTGGATGCGATCCTGTT
CTTAAGCCTTGCGAATATTCGCTACCTGTCAGGCTTTACCGGCTCTGACGGCGCACTGCTGCTCACCCGGGAGGAGTGCC
GTTTGCTGTGCGATTCGCGCTATACGACACAGGCAGCTGCCGAGGTACTGGACGGCGAGGTGCTCCAGTACAGCGATAGA
AATGCTTTGCTACGGGAATTGGTCGACGATCTGGGGTTGTCGCGCATCGGTTTCGAGGCGGCCCACACCACCTTCGCCGC
GTTCAGCGAACTCTCTTCAAGCTTGAAAGGGCATGAACTGGTCTCCCTGGGGGGCGACCTGGACCAGATCCGTTCCTGCA
AAGACCAGGATGAGCTGGAGCGGCTCTCCCGCGTGGCCGGTTTGGCCTCGGATGCCCTTGTTGCCTGTCTGGGAAAATTG
GGTCCCGGTGTCAGCGAGGCCTCTTTTGCCTGGGAACTCGAAAAGGAGATGCGAAACCGCGGCGCCGAGGGCAGGGCCTT
TGATTTCATCGTTGCCTCGGGAGAACGGGGCGCCATGCCCCATGGCCGGGCGTCGGAAAAACTGCTCCGCTCCGGCGAAC
TGGTTACCATCGACTTCGGCGCCTGCATGGACGGATACGTTTCCGACGAGACCGTAACCATTGCCATCGGCACGCCTGAC
CGGCGCGGTGTTGATGTTTACGCCGTTGTCAAGGAGGCCCACGACCTGGCCATTGCAGCGGTCAGACCGGGCATCTCCTG
CCGCGACCTGGATGCCGTTGCCCGCGATCATATCCGCGGTCGCGGCTTTGGCGACTATTTCGGCCATGGCCTGGGGCACG
GGGTCGGTCTTGAGGTTCACGAGAAGCCGGCCATCTCCCCCCGCAACGATATGACCCTCCAGGAGGGGATGGTGTTCACC
ATCGAACCTGGTATCTATATTCCCGGCTTTGGCGGGGTGAGGATCGAGGACACGGTGGTGGTCCTGCCTGATGGCTGCCG
TGCGCTGACGCGGGTTTCAAAAGAGCTGATGTACGTATAG

Upstream 100 bases:

>100_bases
CGGCCCCCTGCACCACGGGATTCACCATGCCTTCAACGAGACAGCGCGGACGATGCGATTCCGATAATGTAATCATCCCT
GGAAAAAACAATTTGTGCTA

Downstream 100 bases:

>100_bases
AGGAGTACCCCGCCTATTGCCGGGGATCCGGTGCCAACCGGGTAAAAGCACGGCCGTATTTCAAAGGAGACAAAAATGGA
TGTTAAAGACCTGCAGGTAC

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MDLPMLHIRRARLERFFTAHDLDAILFLSLANIRYLSGFTGSDGALLLTREECRLLCDSRYTTQAAAEVLDGEVLQYSDR
NALLRELVDDLGLSRIGFEAAHTTFAAFSELSSSLKGHELVSLGGDLDQIRSCKDQDELERLSRVAGLASDALVACLGKL
GPGVSEASFAWELEKEMRNRGAEGRAFDFIVASGERGAMPHGRASEKLLRSGELVTIDFGACMDGYVSDETVTIAIGTPD
RRGVDVYAVVKEAHDLAIAAVRPGISCRDLDAVARDHIRGRGFGDYFGHGLGHGVGLEVHEKPAISPRNDMTLQEGMVFT
IEPGIYIPGFGGVRIEDTVVVLPDGCRALTRVSKELMYV

Sequences:

>Translated_359_residues
MDLPMLHIRRARLERFFTAHDLDAILFLSLANIRYLSGFTGSDGALLLTREECRLLCDSRYTTQAAAEVLDGEVLQYSDR
NALLRELVDDLGLSRIGFEAAHTTFAAFSELSSSLKGHELVSLGGDLDQIRSCKDQDELERLSRVAGLASDALVACLGKL
GPGVSEASFAWELEKEMRNRGAEGRAFDFIVASGERGAMPHGRASEKLLRSGELVTIDFGACMDGYVSDETVTIAIGTPD
RRGVDVYAVVKEAHDLAIAAVRPGISCRDLDAVARDHIRGRGFGDYFGHGLGHGVGLEVHEKPAISPRNDMTLQEGMVFT
IEPGIYIPGFGGVRIEDTVVVLPDGCRALTRVSKELMYV
>Mature_359_residues
MDLPMLHIRRARLERFFTAHDLDAILFLSLANIRYLSGFTGSDGALLLTREECRLLCDSRYTTQAAAEVLDGEVLQYSDR
NALLRELVDDLGLSRIGFEAAHTTFAAFSELSSSLKGHELVSLGGDLDQIRSCKDQDELERLSRVAGLASDALVACLGKL
GPGVSEASFAWELEKEMRNRGAEGRAFDFIVASGERGAMPHGRASEKLLRSGELVTIDFGACMDGYVSDETVTIAIGTPD
RRGVDVYAVVKEAHDLAIAAVRPGISCRDLDAVARDHIRGRGFGDYFGHGLGHGVGLEVHEKPAISPRNDMTLQEGMVFT
IEPGIYIPGFGGVRIEDTVVVLPDGCRALTRVSKELMYV

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=249, Percent_Identity=32.5301204819277, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI264681563, Length=231, Percent_Identity=35.0649350649351, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI93141226, Length=167, Percent_Identity=33.5329341317365, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI264681565, Length=228, Percent_Identity=33.7719298245614, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI40385867, Length=247, Percent_Identity=24.6963562753036, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1788728, Length=355, Percent_Identity=39.1549295774648, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789275, Length=252, Percent_Identity=29.7619047619048, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786364, Length=254, Percent_Identity=28.3464566929134, Blast_Score=78, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17508215, Length=296, Percent_Identity=26.3513513513513, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17509539, Length=163, Percent_Identity=34.3558282208589, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321118, Length=290, Percent_Identity=24.8275862068966, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19920384, Length=374, Percent_Identity=26.2032085561497, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39047; Mature: 39047

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLPMLHIRRARLERFFTAHDLDAILFLSLANIRYLSGFTGSDGALLLTREECRLLCDSR
CCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHCCC
YTTQAAAEVLDGEVLQYSDRNALLRELVDDLGLSRIGFEAAHTTFAAFSELSSSLKGHEL
CHHHHHHHHHCCHHEEECCHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHCCCCEE
VSLGGDLDQIRSCKDQDELERLSRVAGLASDALVACLGKLGPGVSEASFAWELEKEMRNR
EECCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
GAEGRAFDFIVASGERGAMPHGRASEKLLRSGELVTIDFGACMDGYVSDETVTIAIGTPD
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEECCCC
RRGVDVYAVVKEAHDLAIAAVRPGISCRDLDAVARDHIRGRGFGDYFGHGLGHGVGLEVH
CCCCCCEEEEHHHHHEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCEEC
EKPAISPRNDMTLQEGMVFTIEPGIYIPGFGGVRIEDTVVVLPDGCRALTRVSKELMYV
CCCCCCCCCCCCHHCCEEEEECCCEEECCCCCEEEECEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLPMLHIRRARLERFFTAHDLDAILFLSLANIRYLSGFTGSDGALLLTREECRLLCDSR
CCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHCCC
YTTQAAAEVLDGEVLQYSDRNALLRELVDDLGLSRIGFEAAHTTFAAFSELSSSLKGHEL
CHHHHHHHHHCCHHEEECCHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHCCCCEE
VSLGGDLDQIRSCKDQDELERLSRVAGLASDALVACLGKLGPGVSEASFAWELEKEMRNR
EECCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
GAEGRAFDFIVASGERGAMPHGRASEKLLRSGELVTIDFGACMDGYVSDETVTIAIGTPD
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEECCCC
RRGVDVYAVVKEAHDLAIAAVRPGISCRDLDAVARDHIRGRGFGDYFGHGLGHGVGLEVH
CCCCCCEEEEHHHHHEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCEEC
EKPAISPRNDMTLQEGMVFTIEPGIYIPGFGGVRIEDTVVVLPDGCRALTRVSKELMYV
CCCCCCCCCCCCHHCCEEEEECCCEEECCCCCEEEECEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]