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The map label for this gene is celB [H]

Identifier: 118580433

GI number: 118580433

Start: 2166568

End: 2167986

Strand: Reverse

Name: celB [H]

Synonym: Ppro_2017

Alternate gene names: 118580433

Gene position: 2167986-2166568 (Counterclockwise)

Preceding gene: 118580435

Following gene: 118580432

Centisome position: 54.09

GC content: 61.52

Gene sequence:

>1419_bases
ATGACACGTATTTCCTTCGGAACGTCTGGTTGGCGTGGTATTCTCGGCGAGGATTTCACCTTTGACAATGTGCGGGTTGT
CGTGCAGGCGATTGCGGACCATATTGCCGCCGCAGGCGAGCAGCAGGGTGGGGTGGTGATCAGTTGCGACACCCGTTTCA
TGGGCCAGCGCTTTGTCCATGAAGCGGCACGGGTCATGGCGGGGGCGGGCATCACGGCCTTTGTCTGCGAAAGGGATACG
CCTACCCCGGTCATCTCCTTAGAGATCCTGCGCCGCAAAACCGCTGGCGGGATTAATTTTACGGCAAGCCACAACCCTCC
CGAATACAATGGCGTCAAGTTTTCCCCTTCATGGGGGGGACCTGCTCTTCCCGAAACCACCGGGGACATAGAAAGGCGCG
CCAACGACGTGATGGGCAGTCTCTGCCGTCCGTTACCTTCGTTGGAGGACGCCCGGCAGCGCGGTCTACTGGTCTCCATC
GATCCACGGGAGGAGTACCTGCGGGAACTGGAGAACAAGGTCGATTTCGACGCCATCAGGAAGCTGGGAAAGGTGGCGCT
GAACCCGCTCTACGGCACCGCCCGTGGCTATCTTGACGCCCCCCTGCTCCGCCACGGCGTAGCGTTCCGGATGATCAACG
ATCGCCCCGACCCCTATTTTGGCGGTCAACCCCCTGAACCGTCGGAAAGTCACATTCCGGACTTCATCGACCTGGTGAAG
AACGATCCCGAGATCCGTCTGGGCCTGGCAACGGATGGCGATGCCGACCGCTTCGGCATCCTGGATGCGGACGGCAGCTA
CATAGAGCCCAACTACATCATCGCGCTTTTGCTGGATTACCTGATCCGCGTCCGCGGCATTGAGGGAGGCGCTGCCCGCA
GCGTGGCCACATCCCATCTGGTGGATGCCGTTGCCAGGAAACATGGCGTCGAGCTGCACGAGACGCCGGTGGGCTTCAAG
TATGTCGGCGAGTTGATCAGCCAGGACAGGATCGTCATCGGCGGCGAGGAGAGCGCCGGCCTTTCCATCAGGGGGCATGT
GCCCGAAAAGGACGGCATCCTTGCCTGCTTCCTGGTGGCGGAAATGGTGGCCCGTGAGGGGAAAACAGTGCGGGAACTGC
TTGAACGCCTCTACGGAGAGGTGGGGCGCTTCGTTACCCGCCGGGAGAACCTGCGCCTGTCTCCCGAGCTGGAAAAGAGC
TATGCCGCCCGGATCGCCTCACTTCCCGCCCGGATCGCCGGGACGGGGATCCGGGATGTGATCAGGATCGACGGGACCAA
ACTGCTGCTGGATGATGGCTGCTGGATGCTGTTCCGCAAGTCGGGAACGGAGCCGGTGGTGCGTCTCTATGGAGAGGCGT
CGTCGGATGCCCGTCTGGCGGAAGTCATGACCGCTGGCCGCGCCTTTATAGGTAGTTAA

Upstream 100 bases:

>100_bases
AAAAATCCTTTGTATATACGGCTCTTTGACTTGACGGAAACTCAAGGCTGTATTACTTTAACACGACTAAAGCTGTCTTC
TTACTCAAGGATGGTGAGCC

Downstream 100 bases:

>100_bases
TTTTATTCGAGTTGTTCGGAGGAAACACCGATGTGGGATTACACACCGATCGTTAAAGATCATTTTCTGAACCCGCGCAA
CGTTGGGGACATACCCGACG

Product: phosphoglucomutase/phosphomannomutase alpha/beta/subunit

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MTRISFGTSGWRGILGEDFTFDNVRVVVQAIADHIAAAGEQQGGVVISCDTRFMGQRFVHEAARVMAGAGITAFVCERDT
PTPVISLEILRRKTAGGINFTASHNPPEYNGVKFSPSWGGPALPETTGDIERRANDVMGSLCRPLPSLEDARQRGLLVSI
DPREEYLRELENKVDFDAIRKLGKVALNPLYGTARGYLDAPLLRHGVAFRMINDRPDPYFGGQPPEPSESHIPDFIDLVK
NDPEIRLGLATDGDADRFGILDADGSYIEPNYIIALLLDYLIRVRGIEGGAARSVATSHLVDAVARKHGVELHETPVGFK
YVGELISQDRIVIGGEESAGLSIRGHVPEKDGILACFLVAEMVAREGKTVRELLERLYGEVGRFVTRRENLRLSPELEKS
YAARIASLPARIAGTGIRDVIRIDGTKLLLDDGCWMLFRKSGTEPVVRLYGEASSDARLAEVMTAGRAFIGS

Sequences:

>Translated_472_residues
MTRISFGTSGWRGILGEDFTFDNVRVVVQAIADHIAAAGEQQGGVVISCDTRFMGQRFVHEAARVMAGAGITAFVCERDT
PTPVISLEILRRKTAGGINFTASHNPPEYNGVKFSPSWGGPALPETTGDIERRANDVMGSLCRPLPSLEDARQRGLLVSI
DPREEYLRELENKVDFDAIRKLGKVALNPLYGTARGYLDAPLLRHGVAFRMINDRPDPYFGGQPPEPSESHIPDFIDLVK
NDPEIRLGLATDGDADRFGILDADGSYIEPNYIIALLLDYLIRVRGIEGGAARSVATSHLVDAVARKHGVELHETPVGFK
YVGELISQDRIVIGGEESAGLSIRGHVPEKDGILACFLVAEMVAREGKTVRELLERLYGEVGRFVTRRENLRLSPELEKS
YAARIASLPARIAGTGIRDVIRIDGTKLLLDDGCWMLFRKSGTEPVVRLYGEASSDARLAEVMTAGRAFIGS
>Mature_471_residues
TRISFGTSGWRGILGEDFTFDNVRVVVQAIADHIAAAGEQQGGVVISCDTRFMGQRFVHEAARVMAGAGITAFVCERDTP
TPVISLEILRRKTAGGINFTASHNPPEYNGVKFSPSWGGPALPETTGDIERRANDVMGSLCRPLPSLEDARQRGLLVSID
PREEYLRELENKVDFDAIRKLGKVALNPLYGTARGYLDAPLLRHGVAFRMINDRPDPYFGGQPPEPSESHIPDFIDLVKN
DPEIRLGLATDGDADRFGILDADGSYIEPNYIIALLLDYLIRVRGIEGGAARSVATSHLVDAVARKHGVELHETPVGFKY
VGELISQDRIVIGGEESAGLSIRGHVPEKDGILACFLVAEMVAREGKTVRELLERLYGEVGRFVTRRENLRLSPELEKSY
AARIASLPARIAGTGIRDVIRIDGTKLLLDDGCWMLFRKSGTEPVVRLYGEASSDARLAEVMTAGRAFIGS

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=480, Percent_Identity=27.2916666666667, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI290463102, Length=505, Percent_Identity=26.5346534653465, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI133922562, Length=485, Percent_Identity=25.7731958762887, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI290463104, Length=321, Percent_Identity=26.4797507788162, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1786904, Length=496, Percent_Identity=29.2338709677419, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788361, Length=482, Percent_Identity=26.1410788381743, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789566, Length=471, Percent_Identity=23.7791932059448, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17535441, Length=510, Percent_Identity=28.2352941176471, Blast_Score=140, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323752, Length=513, Percent_Identity=26.1208576998051, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6322722, Length=498, Percent_Identity=26.9076305220884, Blast_Score=123, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6323934, Length=422, Percent_Identity=23.696682464455, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17864244, Length=506, Percent_Identity=29.0513833992095, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI20129809, Length=538, Percent_Identity=24.7211895910781, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24651977, Length=452, Percent_Identity=26.3274336283186, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24653722, Length=437, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 51581; Mature: 51450

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRISFGTSGWRGILGEDFTFDNVRVVVQAIADHIAAAGEQQGGVVISCDTRFMGQRFVH
CCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHH
EAARVMAGAGITAFVCERDTPTPVISLEILRRKTAGGINFTASHNPPEYNGVKFSPSWGG
HHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHCCCCEEEECCCCCCCCCCEEECCCCCC
PALPETTGDIERRANDVMGSLCRPLPSLEDARQRGLLVSIDPREEYLRELENKVDFDAIR
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCEEEEECCHHHHHHHHHHCCCHHHHH
KLGKVALNPLYGTARGYLDAPLLRHGVAFRMINDRPDPYFGGQPPEPSESHIPDFIDLVK
HHHHHHHCCCHHCCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHC
NDPEIRLGLATDGDADRFGILDADGSYIEPNYIIALLLDYLIRVRGIEGGAARSVATSHL
CCCCEEEEEECCCCCCCEEEEECCCCEECHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VDAVARKHGVELHETPVGFKYVGELISQDRIVIGGEESAGLSIRGHVPEKDGILACFLVA
HHHHHHHHCCEEECCCCCHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHH
EMVAREGKTVRELLERLYGEVGRFVTRRENLRLSPELEKSYAARIASLPARIAGTGIRDV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHCCCHHHH
IRIDGTKLLLDDGCWMLFRKSGTEPVVRLYGEASSDARLAEVMTAGRAFIGS
EEECCCEEEEECCCEEEEECCCCCHHHEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRISFGTSGWRGILGEDFTFDNVRVVVQAIADHIAAAGEQQGGVVISCDTRFMGQRFVH
CEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHH
EAARVMAGAGITAFVCERDTPTPVISLEILRRKTAGGINFTASHNPPEYNGVKFSPSWGG
HHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHCCCCEEEECCCCCCCCCCEEECCCCCC
PALPETTGDIERRANDVMGSLCRPLPSLEDARQRGLLVSIDPREEYLRELENKVDFDAIR
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCEEEEECCHHHHHHHHHHCCCHHHHH
KLGKVALNPLYGTARGYLDAPLLRHGVAFRMINDRPDPYFGGQPPEPSESHIPDFIDLVK
HHHHHHHCCCHHCCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHC
NDPEIRLGLATDGDADRFGILDADGSYIEPNYIIALLLDYLIRVRGIEGGAARSVATSHL
CCCCEEEEEECCCCCCCEEEEECCCCEECHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VDAVARKHGVELHETPVGFKYVGELISQDRIVIGGEESAGLSIRGHVPEKDGILACFLVA
HHHHHHHHCCEEECCCCCHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHH
EMVAREGKTVRELLERLYGEVGRFVTRRENLRLSPELEKSYAARIASLPARIAGTGIRDV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHCCCHHHH
IRIDGTKLLLDDGCWMLFRKSGTEPVVRLYGEASSDARLAEVMTAGRAFIGS
EEECCCEEEEECCCEEEEECCCCCHHHEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025683 [H]