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The map label for this gene is tadA [H]

Identifier: 118580396

GI number: 118580396

Start: 2123777

End: 2124214

Strand: Reverse

Name: tadA [H]

Synonym: Ppro_1980

Alternate gene names: 118580396

Gene position: 2124214-2123777 (Counterclockwise)

Preceding gene: 118580397

Following gene: 118580395

Centisome position: 53.0

GC content: 63.24

Gene sequence:

>438_bases
ATGGACGAATTCATGCAAGCCGCCTTAGAAGAGGCGCGGAAGGGGCTGGCCGAGGGGGGCATTCCCATCGGCTCGCTCGT
GGTGCACCGGGGGGCTGTTCTGGGAAGGGGGCATAACCGGCGGGTGCAGAAGGGGAGCGTGATACTTCACGCAGAGATGG
ATGCCCTGGAGAACGCGGGGCGGATGCCGGCAGCCATCTACCGCGAGTCGGTGCTGTATACGACGTTGTCCCCCTGTCCC
ATGTGTGCGGGAGCGATCCTGCTCTACGGTATTCCGCGGGTGGTCATTGGAGAAAACAGGAACTTCCGGGGCGAGGAGGA
ACTGCTCCGCTCCCGCGGCGTGCAGGTGGAACTGCTGCAGGACGAGGAGTGCATCGCCCTGATGCGCCAGTTTATCGACA
ACAGGCCGGACCTGTGGAACGAGGATATCGGCGTGTGA

Upstream 100 bases:

>100_bases
TGCTGACAAAAGAGACGCCGCAGATTGCCTGTTGCCGAGCCGAGGCTACACTTGAAGACGATACACTCCCGCCGCCAGCG
GAGAGAGGGGGAAGACGGAT

Downstream 100 bases:

>100_bases
CACTCCCGTGGAGCCGTCATGCCGGTGACCAGGTCTGAAACGTGGCGGGGTCCCCCGGCAATCACCGGGAACGCCAGTGT
GAAAAGGAGACTACATATGA

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MDEFMQAALEEARKGLAEGGIPIGSLVVHRGAVLGRGHNRRVQKGSVILHAEMDALENAGRMPAAIYRESVLYTTLSPCP
MCAGAILLYGIPRVVIGENRNFRGEEELLRSRGVQVELLQDEECIALMRQFIDNRPDLWNEDIGV

Sequences:

>Translated_145_residues
MDEFMQAALEEARKGLAEGGIPIGSLVVHRGAVLGRGHNRRVQKGSVILHAEMDALENAGRMPAAIYRESVLYTTLSPCP
MCAGAILLYGIPRVVIGENRNFRGEEELLRSRGVQVELLQDEECIALMRQFIDNRPDLWNEDIGV
>Mature_145_residues
MDEFMQAALEEARKGLAEGGIPIGSLVVHRGAVLGRGHNRRVQKGSVILHAEMDALENAGRMPAAIYRESVLYTTLSPCP
MCAGAILLYGIPRVVIGENRNFRGEEELLRSRGVQVELLQDEECIALMRQFIDNRPDLWNEDIGV

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=111, Percent_Identity=35.1351351351351, Blast_Score=77, Evalue=7e-15,
Organism=Escherichia coli, GI145693172, Length=143, Percent_Identity=34.2657342657343, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=38.1443298969072, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17541138, Length=143, Percent_Identity=32.1678321678322, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6325319, Length=143, Percent_Identity=54.5454545454545, Blast_Score=168, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16072; Mature: 16072

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEFMQAALEEARKGLAEGGIPIGSLVVHRGAVLGRGHNRRVQKGSVILHAEMDALENAG
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEECCCCEEEEECHHHHHCCC
RMPAAIYRESVLYTTLSPCPMCAGAILLYGIPRVVIGENRNFRGEEELLRSRGVQVELLQ
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCCEEEEEC
DEECIALMRQFIDNRPDLWNEDIGV
CHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDEFMQAALEEARKGLAEGGIPIGSLVVHRGAVLGRGHNRRVQKGSVILHAEMDALENAG
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEECCCCEEEEECHHHHHCCC
RMPAAIYRESVLYTTLSPCPMCAGAILLYGIPRVVIGENRNFRGEEELLRSRGVQVELLQ
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCCEEEEEC
DEECIALMRQFIDNRPDLWNEDIGV
CHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]