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The map label for this gene is ygbD [C]

Identifier: 118580390

GI number: 118580390

Start: 2118119

End: 2119810

Strand: Direct

Name: ygbD [C]

Synonym: Ppro_1974

Alternate gene names: 118580390

Gene position: 2118119-2119810 (Clockwise)

Preceding gene: 118580389

Following gene: 118580391

Centisome position: 52.85

GC content: 61.76

Gene sequence:

>1692_bases
ATGAGTAAACGGATCATTGTCATTGGAGGATCGGCGGCCGGTCCCAAGGCCGCGGCACGGGCAAAACGGCTCGACCCCTC
GGCAGAGGTAACCATCATCCAGAAGGCGCCGGAAATGTCCATGGCGTCCTGCGGCTACCCCTATTTTGTGGCTGGGGTAT
TCAACAACCGCAACGCCCTGATCAGCACACCCTACGGCGAGGTTCGCGACCCCAACTTCTTCGTGAACACCAAGGGAATC
CGTGCCCGCACCGAAACCGAAGTAACCGCCATCGACCGTACGCAACGTACCGTTACCTGCCGTGACCTGAAAAGCGGCGT
CCTCGACCAGTTGAGCTATGACAAGCTGATCATCGCCACCGGTGCCAAGCCGCGCAAACCTCCCGTACCGGGCATCGACC
TGGAAGGGGTGACAACGCTCCAATCCATGCGTGACGCCGATTTCCTGCGCCGTATCCGCGACGAGGGCGCCGTCAAAAAG
GCGGTGGTCATCGGCGGCGGCCTGATCGGCATTGAGACCTGCGAGGCATTGCAGTTGTCCGGCATCGACATCACGGTTAT
CGAAATGCTGCCCCAGATCCTGATGTTCCTGGACTGGGAACTGGCCGAGATACTGGAAAACCATGTGCGCAGCAAGGCTG
CCAATGTGATTACCGATGTCAAACTGGCAGGATTCCTGGGTGAAAACGGCAGACTGACGGCGGTCAGACTGGAGAATGGC
ACGGAACTGCCGTGCGAACTGGCGGTGCTGGCCATCGGCGTCATTCCCAACACAGATCTGGCCCAGGCAGCCGGACTTAC
CATCGGCGCCACCGGCGGCATCCTGGTGGATGAACACCTGAGGACCTCCGACCCGCATATCTACGCCGTGGGCGACTGCA
TCGAACTGGTGCAGCGCATAACCGGCGGAAAAACCCGCGCGCCCTTCGGCGACTTGGCCAATCTGGAGGGACGTGTGGCC
GGTGAGAACGCCGTACTGGGCGACAGCGTCACCTTCCCCGGCACCTTCCACACCGGTATCTGCAAAGTTTTCGACTTCAA
TGCCGGCTCCACCGGCCTCTCGGAGGGCAAGGCCCGCCAGGAAGGCTTCAACGTCGCCACGGTGATCAACGCAAGTCTGG
ACAAGCCGGAGTTCATGGGCGCCAAGCTGCTCATCTCCAAGATGGTGGTGGATGCCGACAGCGGCAGACTGTTGGGCGTG
CAGTGCGTGGGGCCGGGCGACGTGGGCAAGCAGATCGCCACGGCGGCCATGGCGCTCTTGGGGAAACTGACGGTTGCCGA
CCTGGTGAATGCCGACCTCCCCTACGCGCCCCCCTTCTCACTGGCCATCGACCACTTCATCGCCACCGCCCACCTGATGG
AGAACAAGCTGAAAGGGAGGCTGAACGGCATCGGTCCTGTCCAACTCAAGGAGAAGCTGGACAGGGGAGAGACCCCCTTC
CTGCTGGACGTGCGTACCCCGGACGAGTTCGACATGATGCGTATCGGTATCGGGGAGACGTTGATTCCCCTGGGTGACCT
GCGGCGCAGGCTGGCCGACCTGCCCCAGGACAGGGAGCGGGAGATCGTCTGCTACTGCAAGATATCCCTCAGGGGGTACG
AAGCGGCAATCCTGCTGCAGGCAGCCGGATGGAAAAACGTCAAGGTTCTGGAGGGTGGGGTCATGGCCTGGCCGTACCGG
CGGGAGAAATGA

Upstream 100 bases:

>100_bases
ACACCGGATTGCACACTTCAGGGAAAACAATAGAGTCATCGACAGCATGCCGTAAGCGGCCCGCTGGACCTGCACTACAA
CAAACGGAGGAGGAGAAAAC

Downstream 100 bases:

>100_bases
GATTCATGACGCGTGAAACCTGAGCTTCGCTCAAAAGGAAGGATCCCATGTGGGATTATCAGTCCCTTGGCCGGGGTTAT
ACCTAGCAGGGCACAATTGT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MSKRIIVIGGSAAGPKAAARAKRLDPSAEVTIIQKAPEMSMASCGYPYFVAGVFNNRNALISTPYGEVRDPNFFVNTKGI
RARTETEVTAIDRTQRTVTCRDLKSGVLDQLSYDKLIIATGAKPRKPPVPGIDLEGVTTLQSMRDADFLRRIRDEGAVKK
AVVIGGGLIGIETCEALQLSGIDITVIEMLPQILMFLDWELAEILENHVRSKAANVITDVKLAGFLGENGRLTAVRLENG
TELPCELAVLAIGVIPNTDLAQAAGLTIGATGGILVDEHLRTSDPHIYAVGDCIELVQRITGGKTRAPFGDLANLEGRVA
GENAVLGDSVTFPGTFHTGICKVFDFNAGSTGLSEGKARQEGFNVATVINASLDKPEFMGAKLLISKMVVDADSGRLLGV
QCVGPGDVGKQIATAAMALLGKLTVADLVNADLPYAPPFSLAIDHFIATAHLMENKLKGRLNGIGPVQLKEKLDRGETPF
LLDVRTPDEFDMMRIGIGETLIPLGDLRRRLADLPQDREREIVCYCKISLRGYEAAILLQAAGWKNVKVLEGGVMAWPYR
REK

Sequences:

>Translated_563_residues
MSKRIIVIGGSAAGPKAAARAKRLDPSAEVTIIQKAPEMSMASCGYPYFVAGVFNNRNALISTPYGEVRDPNFFVNTKGI
RARTETEVTAIDRTQRTVTCRDLKSGVLDQLSYDKLIIATGAKPRKPPVPGIDLEGVTTLQSMRDADFLRRIRDEGAVKK
AVVIGGGLIGIETCEALQLSGIDITVIEMLPQILMFLDWELAEILENHVRSKAANVITDVKLAGFLGENGRLTAVRLENG
TELPCELAVLAIGVIPNTDLAQAAGLTIGATGGILVDEHLRTSDPHIYAVGDCIELVQRITGGKTRAPFGDLANLEGRVA
GENAVLGDSVTFPGTFHTGICKVFDFNAGSTGLSEGKARQEGFNVATVINASLDKPEFMGAKLLISKMVVDADSGRLLGV
QCVGPGDVGKQIATAAMALLGKLTVADLVNADLPYAPPFSLAIDHFIATAHLMENKLKGRLNGIGPVQLKEKLDRGETPF
LLDVRTPDEFDMMRIGIGETLIPLGDLRRRLADLPQDREREIVCYCKISLRGYEAAILLQAAGWKNVKVLEGGVMAWPYR
REK
>Mature_562_residues
SKRIIVIGGSAAGPKAAARAKRLDPSAEVTIIQKAPEMSMASCGYPYFVAGVFNNRNALISTPYGEVRDPNFFVNTKGIR
ARTETEVTAIDRTQRTVTCRDLKSGVLDQLSYDKLIIATGAKPRKPPVPGIDLEGVTTLQSMRDADFLRRIRDEGAVKKA
VVIGGGLIGIETCEALQLSGIDITVIEMLPQILMFLDWELAEILENHVRSKAANVITDVKLAGFLGENGRLTAVRLENGT
ELPCELAVLAIGVIPNTDLAQAAGLTIGATGGILVDEHLRTSDPHIYAVGDCIELVQRITGGKTRAPFGDLANLEGRVAG
ENAVLGDSVTFPGTFHTGICKVFDFNAGSTGLSEGKARQEGFNVATVINASLDKPEFMGAKLLISKMVVDADSGRLLGVQ
CVGPGDVGKQIATAAMALLGKLTVADLVNADLPYAPPFSLAIDHFIATAHLMENKLKGRLNGIGPVQLKEKLDRGETPFL
LDVRTPDEFDMMRIGIGETLIPLGDLRRRLADLPQDREREIVCYCKISLRGYEAAILLQAAGWKNVKVLEGGVMAWPYRR
EK

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=256, Percent_Identity=25.78125, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI21389617, Length=256, Percent_Identity=25.78125, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI226437568, Length=256, Percent_Identity=25.78125, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI22202629, Length=329, Percent_Identity=26.4437689969605, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI4757732, Length=329, Percent_Identity=26.4437689969605, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1789065, Length=300, Percent_Identity=28.6666666666667, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789765, Length=334, Percent_Identity=27.5449101796407, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87082354, Length=371, Percent_Identity=22.3719676549865, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786307, Length=304, Percent_Identity=27.3026315789474, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788892, Length=206, Percent_Identity=30.5825242718447, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=233, Percent_Identity=31.7596566523605, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32564386, Length=376, Percent_Identity=23.4042553191489, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24585130, Length=332, Percent_Identity=22.5903614457831, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281359715, Length=245, Percent_Identity=26.9387755102041, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281359713, Length=245, Percent_Identity=26.9387755102041, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639250, Length=245, Percent_Identity=26.9387755102041, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI18543267, Length=245, Percent_Identity=26.9387755102041, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639252, Length=245, Percent_Identity=26.9387755102041, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639257, Length=245, Percent_Identity=26.9387755102041, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 60553; Mature: 60422

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRIIVIGGSAAGPKAAARAKRLDPSAEVTIIQKAPEMSMASCGYPYFVAGVFNNRNAL
CCCEEEEEECCCCCCHHHHHHHCCCCCCCEEEEECCCCCCHHHCCCCEEEEEEECCCCEE
ISTPYGEVRDPNFFVNTKGIRARTETEVTAIDRTQRTVTCRDLKSGVLDQLSYDKLIIAT
EECCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHCCCCEEEEEE
GAKPRKPPVPGIDLEGVTTLQSMRDADFLRRIRDEGAVKKAVVIGGGLIGIETCEALQLS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCEEEEC
GIDITVIEMLPQILMFLDWELAEILENHVRSKAANVITDVKLAGFLGENGRLTAVRLENG
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEECCC
TELPCELAVLAIGVIPNTDLAQAAGLTIGATGGILVDEHLRTSDPHIYAVGDCIELVQRI
CCCCCEEEEEEEECCCCCCHHHHCCEEEECCCCEEEECCCCCCCCEEEEHHHHHHHHHHH
TGGKTRAPFGDLANLEGRVAGENAVLGDSVTFPGTFHTGICKVFDFNAGSTGLSEGKARQ
CCCCCCCCCCCCCCCCCEECCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHH
EGFNVATVINASLDKPEFMGAKLLISKMVVDADSGRLLGVQCVGPGDVGKQIATAAMALL
CCCCEEEEEECCCCCCHHHHHHHHHHHHHEECCCCCEEEEEEECCCHHHHHHHHHHHHHH
GKLTVADLVNADLPYAPPFSLAIDHFIATAHLMENKLKGRLNGIGPVQLKEKLDRGETPF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCE
LLDVRTPDEFDMMRIGIGETLIPLGDLRRRLADLPQDREREIVCYCKISLRGYEAAILLQ
EEEECCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEECCCEEEEEEE
AAGWKNVKVLEGGVMAWPYRREK
ECCCCCEEEEECCEEECCCCCCC
>Mature Secondary Structure 
SKRIIVIGGSAAGPKAAARAKRLDPSAEVTIIQKAPEMSMASCGYPYFVAGVFNNRNAL
CCEEEEEECCCCCCHHHHHHHCCCCCCCEEEEECCCCCCHHHCCCCEEEEEEECCCCEE
ISTPYGEVRDPNFFVNTKGIRARTETEVTAIDRTQRTVTCRDLKSGVLDQLSYDKLIIAT
EECCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHCCCCEEEEEE
GAKPRKPPVPGIDLEGVTTLQSMRDADFLRRIRDEGAVKKAVVIGGGLIGIETCEALQLS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCEEEEC
GIDITVIEMLPQILMFLDWELAEILENHVRSKAANVITDVKLAGFLGENGRLTAVRLENG
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEECCC
TELPCELAVLAIGVIPNTDLAQAAGLTIGATGGILVDEHLRTSDPHIYAVGDCIELVQRI
CCCCCEEEEEEEECCCCCCHHHHCCEEEECCCCEEEECCCCCCCCEEEEHHHHHHHHHHH
TGGKTRAPFGDLANLEGRVAGENAVLGDSVTFPGTFHTGICKVFDFNAGSTGLSEGKARQ
CCCCCCCCCCCCCCCCCEECCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHH
EGFNVATVINASLDKPEFMGAKLLISKMVVDADSGRLLGVQCVGPGDVGKQIATAAMALL
CCCCEEEEEECCCCCCHHHHHHHHHHHHHEECCCCCEEEEEEECCCHHHHHHHHHHHHHH
GKLTVADLVNADLPYAPPFSLAIDHFIATAHLMENKLKGRLNGIGPVQLKEKLDRGETPF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCE
LLDVRTPDEFDMMRIGIGETLIPLGDLRRRLADLPQDREREIVCYCKISLRGYEAAILLQ
EEEECCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEECCCEEEEEEE
AAGWKNVKVLEGGVMAWPYRREK
ECCCCCEEEEECCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA