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The map label for this gene is arpC [H]

Identifier: 118580332

GI number: 118580332

Start: 2065315

End: 2066802

Strand: Reverse

Name: arpC [H]

Synonym: Ppro_1915

Alternate gene names: 118580332

Gene position: 2066802-2065315 (Counterclockwise)

Preceding gene: 118580333

Following gene: 118580331

Centisome position: 51.57

GC content: 60.82

Gene sequence:

>1488_bases
ATGGAGCACGCTAAAACATGCCAGCGCCCCATCAGCCTCGAAAGACGGCTTGCGGCAACTTACCTAGTAGCTGGTCTGGT
CACCGCCGGTCTGGCCGGCTGCGCCGCCGGCCCTGATTTTCAGCGTCCCACCGCACCCGATGTGGCTCGCTACACTGCAA
CACCGGTAGCTGATAGAACCGCGTCCGCTCCCACGCAGTTCGGCGAAACACAACGTCTAGTCGAAGGGCTTCCGATCGAA
ACGCAATGGTGGCAAAGCTTGGGTTCATCCGCACTCGACGGACTGATCAACGAAGCTTTCCATGTCAGCCCGACGCTGGC
GAGCATCAGCGCCAATTTGCGACAGGCGCAGGAGCTTCTTGCCGCACAGGCGGGCTCGACGCAATATCCACAGGTAGATG
TCGCACTGGGATCTCAGCGCCAGCAAATGAGTCCCAGTAGCCAAGGGTTGAGCGGAGACGCACGTCAATTCAGCCTCTAC
AACGCCAGCGTTGGCGTGCATTACAACCTCGATCTGGCTGGCGGCAACCGGCGCGCACTCGAAGCCTTGGCTGCTCGCGC
CGACTACCGTCGCTTCGAACTGAATGCTGCGCGCCTGGCCCTTGCCGGCAATATGGCAACCGCTGCCATTACCCGAGCAC
GCCTCGCCGCGCAACTAGAAGCCACTACTGCCATTTTGCGCGTGCAGGATGAGCAACTGCGCCTAGCCCATGAACGCGTG
CGTATCGGTCAGGCCTCACCTGATGAAGCGTTAAGCCTACAAGCTCAGGCGGAGCAAACGCGGGCAGAACTGCCTGCGCT
GCGTAAACAACTGCAACAAACCGAACATCTACTGGCGGTGCTAGCCGGTCGTGCCCCAGGCACGGGTGGCATCCCGGCCT
TCACTCTGGCCGATTTCACTCTGCCCGTCGAGATGCCGCTCGTCGTGCCCTCAGAACTGGTGCGCCGCCGACCGGATATC
CAGGCGTCAGAGGCGCTGTTGCATGCGGCCAATGCAGACTATGGTGTGGCTATCGCCAAGCTCTACCCACAGATCAACCT
GAGCGCCAACCTTGGCTCTCAAGCGCTGACCACCGGTGCCCTGTTCGGTGGTGGCTCGGCAGTGTGGGGCCTGGTTGCGC
AGCTCACCCAACCTCTTTTTAATCCAGGGCTACCCGCTGAAAAAAGAGCGGCGCTCGCCGCTTTTGATGCCGCCGCAGCC
AATTACCAGAGCGTCGTGTTGGAGTCTTTGCGTAACGTCGCCGACACCCTGCGCGCGGTGGAAAGCGATGCACAAACTTT
GACTGCCCTCGCTGCCGCTGATATGGCTGCACAGGCCTCCTTGCAGTCGGTCGAGCGGCAATACCGGCTGGGCGCGGCCA
GCTACCTGCAACTGCTCATCGCGCAGCAACAGGCACAGTCAATCCGGATCAATATGGTTGCGGCCCAGGCACAACGCCTA
GTCGATAGTGTTGCTTTATATCAGGCCCTGGGAGGTGGTGTCAGTTAA

Upstream 100 bases:

>100_bases
AGCAGCGACGGCAAGGCGGTGATCCAATCATTCGCCCACGTGCAGGAAAGCTGCTTGGGCTGCCACCAAGCTTTCCGTAA
ACCTTTCGTGGAGCATTTTT

Downstream 100 bases:

>100_bases
GGCTATACCCTAACCTGATGTCAGATGTTGAGCACAAACAACGTCAGAGTAGGGTATTAATTTATATTTATTGACACATT
CAGCCAAGGGTAATAGATCT

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MEHAKTCQRPISLERRLAATYLVAGLVTAGLAGCAAGPDFQRPTAPDVARYTATPVADRTASAPTQFGETQRLVEGLPIE
TQWWQSLGSSALDGLINEAFHVSPTLASISANLRQAQELLAAQAGSTQYPQVDVALGSQRQQMSPSSQGLSGDARQFSLY
NASVGVHYNLDLAGGNRRALEALAARADYRRFELNAARLALAGNMATAAITRARLAAQLEATTAILRVQDEQLRLAHERV
RIGQASPDEALSLQAQAEQTRAELPALRKQLQQTEHLLAVLAGRAPGTGGIPAFTLADFTLPVEMPLVVPSELVRRRPDI
QASEALLHAANADYGVAIAKLYPQINLSANLGSQALTTGALFGGGSAVWGLVAQLTQPLFNPGLPAEKRAALAAFDAAAA
NYQSVVLESLRNVADTLRAVESDAQTLTALAAADMAAQASLQSVERQYRLGAASYLQLLIAQQQAQSIRINMVAAQAQRL
VDSVALYQALGGGVS

Sequences:

>Translated_495_residues
MEHAKTCQRPISLERRLAATYLVAGLVTAGLAGCAAGPDFQRPTAPDVARYTATPVADRTASAPTQFGETQRLVEGLPIE
TQWWQSLGSSALDGLINEAFHVSPTLASISANLRQAQELLAAQAGSTQYPQVDVALGSQRQQMSPSSQGLSGDARQFSLY
NASVGVHYNLDLAGGNRRALEALAARADYRRFELNAARLALAGNMATAAITRARLAAQLEATTAILRVQDEQLRLAHERV
RIGQASPDEALSLQAQAEQTRAELPALRKQLQQTEHLLAVLAGRAPGTGGIPAFTLADFTLPVEMPLVVPSELVRRRPDI
QASEALLHAANADYGVAIAKLYPQINLSANLGSQALTTGALFGGGSAVWGLVAQLTQPLFNPGLPAEKRAALAAFDAAAA
NYQSVVLESLRNVADTLRAVESDAQTLTALAAADMAAQASLQSVERQYRLGAASYLQLLIAQQQAQSIRINMVAAQAQRL
VDSVALYQALGGGVS
>Mature_495_residues
MEHAKTCQRPISLERRLAATYLVAGLVTAGLAGCAAGPDFQRPTAPDVARYTATPVADRTASAPTQFGETQRLVEGLPIE
TQWWQSLGSSALDGLINEAFHVSPTLASISANLRQAQELLAAQAGSTQYPQVDVALGSQRQQMSPSSQGLSGDARQFSLY
NASVGVHYNLDLAGGNRRALEALAARADYRRFELNAARLALAGNMATAAITRARLAAQLEATTAILRVQDEQLRLAHERV
RIGQASPDEALSLQAQAEQTRAELPALRKQLQQTEHLLAVLAGRAPGTGGIPAFTLADFTLPVEMPLVVPSELVRRRPDI
QASEALLHAANADYGVAIAKLYPQINLSANLGSQALTTGALFGGGSAVWGLVAQLTQPLFNPGLPAEKRAALAAFDAAAA
NYQSVVLESLRNVADTLRAVESDAQTLTALAAADMAAQASLQSVERQYRLGAASYLQLLIAQQQAQSIRINMVAAQAQRL
VDSVALYQALGGGVS

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=482, Percent_Identity=25.7261410788382, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI2367348, Length=447, Percent_Identity=26.8456375838926, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52295; Mature: 52295

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHAKTCQRPISLERRLAATYLVAGLVTAGLAGCAAGPDFQRPTAPDVARYTATPVADRT
CCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCC
ASAPTQFGETQRLVEGLPIETQWWQSLGSSALDGLINEAFHVSPTLASISANLRQAQELL
CCCCHHHCHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAQAGSTQYPQVDVALGSQRQQMSPSSQGLSGDARQFSLYNASVGVHYNLDLAGGNRRAL
HHHCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCCEEEEEECEEEEEEEEEECCCCHHHH
EALAARADYRRFELNAARLALAGNMATAAITRARLAAQLEATTAILRVQDEQLRLAHERV
HHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHH
RIGQASPDEALSLQAQAEQTRAELPALRKQLQQTEHLLAVLAGRAPGTGGIPAFTLADFT
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCEE
LPVEMPLVVPSELVRRRPDIQASEALLHAANADYGVAIAKLYPQINLSANLGSQALTTGA
ECCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCEEHHHHCCCCEECCCCCCHHHHHHH
LFGGGSAVWGLVAQLTQPLFNPGLPAEKRAALAAFDAAAANYQSVVLESLRNVADTLRAV
HCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESDAQTLTALAAADMAAQASLQSVERQYRLGAASYLQLLIAQQQAQSIRINMVAAQAQRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDSVALYQALGGGVS
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MEHAKTCQRPISLERRLAATYLVAGLVTAGLAGCAAGPDFQRPTAPDVARYTATPVADRT
CCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCC
ASAPTQFGETQRLVEGLPIETQWWQSLGSSALDGLINEAFHVSPTLASISANLRQAQELL
CCCCHHHCHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAQAGSTQYPQVDVALGSQRQQMSPSSQGLSGDARQFSLYNASVGVHYNLDLAGGNRRAL
HHHCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCCEEEEEECEEEEEEEEEECCCCHHHH
EALAARADYRRFELNAARLALAGNMATAAITRARLAAQLEATTAILRVQDEQLRLAHERV
HHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHH
RIGQASPDEALSLQAQAEQTRAELPALRKQLQQTEHLLAVLAGRAPGTGGIPAFTLADFT
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCEE
LPVEMPLVVPSELVRRRPDIQASEALLHAANADYGVAIAKLYPQINLSANLGSQALTTGA
ECCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCEEHHHHCCCCEECCCCCCHHHHHHH
LFGGGSAVWGLVAQLTQPLFNPGLPAEKRAALAAFDAAAANYQSVVLESLRNVADTLRAV
HCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESDAQTLTALAAADMAAQASLQSVERQYRLGAASYLQLLIAQQQAQSIRINMVAAQAQRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDSVALYQALGGGVS
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]