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The map label for this gene is hsdM [C]

Identifier: 118580277

GI number: 118580277

Start: 1999827

End: 2001449

Strand: Reverse

Name: hsdM [C]

Synonym: Ppro_1858

Alternate gene names: 118580277

Gene position: 2001449-1999827 (Counterclockwise)

Preceding gene: 118580279

Following gene: 118580276

Centisome position: 49.94

GC content: 64.26

Gene sequence:

>1623_bases
ATGAATCCCGAGCTGATCAAGACCCTCTGGGCCACCGCCGACAAGCTGCGCGCCAACATGGACGCCGCCGAGTACAAGCA
CATCGTGCTCGGCCTCATCTTCGTCAAATACATCTCCGACACCTTCCAGACTCGCAGCTCTGAGTTGCGGGAGCGCTTCG
GCAATCCCGATGACGAGTATTACATCCAGGATGCCGACGACGAAACCCTGGTCTGCGAGCTGGAGGACCGGGACTATTAC
CGGGAGGTGAACACCTTCTGGGTGCCGGAGGCGGCGCGCTGGGAGAATATCCGGGCGCAGGCCAAGCAGCCCGACATCGG
CAAGCGCATCGACGACGCCCTGACCCTGATCGAGGCCGAAAACCCCAAGCTGAAAGGGATCCTTGACAAACGCTATGCCC
GCGTGCAGCTCCCCGACGGCAAGCTGGGGGAGCTGGTGGACATGGTCTCCACCATCGGTTTCGGCGTCACCGGGGAGAGC
GCCCGCGACATCCTGGGGCAGGTGTACGAGTATTTCCTGGGCCAGTTCGCCAGCGCCGAGGGGAAGCGGGGCGGCCAGTT
CTACACGCCGGCCAGCATCGTCAGGACCCTGGTGGCGATTCTCGCCCCTCATCATGGCCAGGTGTACGACCCCTGCTGCG
GTTCCGGCGGCATGTTCGTCCAATCGGAAAAGTTCATCGAAGCCCACGGCGGCAGGATCGGCGATGTCTCCATCTACGGC
CAGGAGTCCAACCCCACCACCTGGCGGCTGGCGGCCATGAACCTGGCCATTCGCGGCATCGACTTCAACCTGGGCAAGGA
GCCGGCCGACACCTTCGTCCGCAACCAGCACCCCGACCTGCGGGCCGACTTCGTGCTGGCCAACCCGCCCTTCAACGTCT
CCGACTGGTGGCACCCCAGCCTGGAGGGTGACCCGCGCTGGGAGTACGGCACGCCGCCCCAGGGGAACGCCAACTACGCC
TGGCTGCAGCACATGCTCTACCACCTGAAACCGACCGGCCGGGCCGGCATCGTGCTGGCCAACGGTTCCATGTCCTCCAG
CCAGAACTCCGAGGGGGAGATCCGCCGCGCCCTGGTGGAGGCGGACAAGGTGGAGGTCATGGTGGCCATGCCGGGGCAGC
TCTTCTTCAACACCCAGATCCCGGCCTGCCTCTGGTTCCTGGCCAAACAGAAGAGCGTCCGCCAGGGAGAGGTGCTGTTC
ATCGACGCTCGCAAGCTGGGCACCATGATCAGCCGGGTGCAGATCGAGTTCAGCGACGAGGATATTCAGAGGATCGCCGA
CACCGTGCATGCGTGGCGTGGTGATGGTGAAATCCCCCTCAATCCCCCTTTGCCAAAGGGGGAGGCCGAAACAATTCCCC
CCTTTACTAAAGGGGGGCCGGGGGGGATTTATCAGGACATCCCCGGCTTCTGCCGCAGCGTGTCACTTGCCGAAATCGCC
GAGCACGGCCATGTCCTGACGCCGGGGCGCTATGTGGGTGCAGAGGCGGTGGAGGACGACGACGAGGCATTCACCGAGAA
GATGCAGCGGTTGACCGAGACCCTGGGCGAGCAGATGGCCAGGGGCGCGGAACTGGACGAGCTGATACGCCGGAAGCTGG
GAGGGCTGGGGTATGAGTTCTGA

Upstream 100 bases:

>100_bases
ATACTCATTCCATTGTTATTCTGCTCTGATTTCTGCTATGTAAGAAAGCTCATGTGAACCGTTGACATGCACCACCACCC
CACCGGAGGCCTGCCACCCC

Downstream 100 bases:

>100_bases
GTGGCCGTATAAAAAACTATCTTTATTGGGTACCTTCGATAGGGGCAAATCTAAACATCGTCCTCGCGATGCTGCACATT
TATACGGTGGGCCTTATCCG

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MNPELIKTLWATADKLRANMDAAEYKHIVLGLIFVKYISDTFQTRSSELRERFGNPDDEYYIQDADDETLVCELEDRDYY
REVNTFWVPEAARWENIRAQAKQPDIGKRIDDALTLIEAENPKLKGILDKRYARVQLPDGKLGELVDMVSTIGFGVTGES
ARDILGQVYEYFLGQFASAEGKRGGQFYTPASIVRTLVAILAPHHGQVYDPCCGSGGMFVQSEKFIEAHGGRIGDVSIYG
QESNPTTWRLAAMNLAIRGIDFNLGKEPADTFVRNQHPDLRADFVLANPPFNVSDWWHPSLEGDPRWEYGTPPQGNANYA
WLQHMLYHLKPTGRAGIVLANGSMSSSQNSEGEIRRALVEADKVEVMVAMPGQLFFNTQIPACLWFLAKQKSVRQGEVLF
IDARKLGTMISRVQIEFSDEDIQRIADTVHAWRGDGEIPLNPPLPKGEAETIPPFTKGGPGGIYQDIPGFCRSVSLAEIA
EHGHVLTPGRYVGAEAVEDDDEAFTEKMQRLTETLGEQMARGAELDELIRRKLGGLGYEF

Sequences:

>Translated_540_residues
MNPELIKTLWATADKLRANMDAAEYKHIVLGLIFVKYISDTFQTRSSELRERFGNPDDEYYIQDADDETLVCELEDRDYY
REVNTFWVPEAARWENIRAQAKQPDIGKRIDDALTLIEAENPKLKGILDKRYARVQLPDGKLGELVDMVSTIGFGVTGES
ARDILGQVYEYFLGQFASAEGKRGGQFYTPASIVRTLVAILAPHHGQVYDPCCGSGGMFVQSEKFIEAHGGRIGDVSIYG
QESNPTTWRLAAMNLAIRGIDFNLGKEPADTFVRNQHPDLRADFVLANPPFNVSDWWHPSLEGDPRWEYGTPPQGNANYA
WLQHMLYHLKPTGRAGIVLANGSMSSSQNSEGEIRRALVEADKVEVMVAMPGQLFFNTQIPACLWFLAKQKSVRQGEVLF
IDARKLGTMISRVQIEFSDEDIQRIADTVHAWRGDGEIPLNPPLPKGEAETIPPFTKGGPGGIYQDIPGFCRSVSLAEIA
EHGHVLTPGRYVGAEAVEDDDEAFTEKMQRLTETLGEQMARGAELDELIRRKLGGLGYEF
>Mature_540_residues
MNPELIKTLWATADKLRANMDAAEYKHIVLGLIFVKYISDTFQTRSSELRERFGNPDDEYYIQDADDETLVCELEDRDYY
REVNTFWVPEAARWENIRAQAKQPDIGKRIDDALTLIEAENPKLKGILDKRYARVQLPDGKLGELVDMVSTIGFGVTGES
ARDILGQVYEYFLGQFASAEGKRGGQFYTPASIVRTLVAILAPHHGQVYDPCCGSGGMFVQSEKFIEAHGGRIGDVSIYG
QESNPTTWRLAAMNLAIRGIDFNLGKEPADTFVRNQHPDLRADFVLANPPFNVSDWWHPSLEGDPRWEYGTPPQGNANYA
WLQHMLYHLKPTGRAGIVLANGSMSSSQNSEGEIRRALVEADKVEVMVAMPGQLFFNTQIPACLWFLAKQKSVRQGEVLF
IDARKLGTMISRVQIEFSDEDIQRIADTVHAWRGDGEIPLNPPLPKGEAETIPPFTKGGPGGIYQDIPGFCRSVSLAEIA
EHGHVLTPGRYVGAEAVEDDDEAFTEKMQRLTETLGEQMARGAELDELIRRKLGGLGYEF

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=319, Percent_Identity=21.9435736677116, Blast_Score=96, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 60351; Mature: 60351

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPELIKTLWATADKLRANMDAAEYKHIVLGLIFVKYISDTFQTRSSELRERFGNPDDEY
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
YIQDADDETLVCELEDRDYYREVNTFWVPEAARWENIRAQAKQPDIGKRIDDALTLIEAE
EEECCCCCEEEEEECCCHHHHHCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHEEECC
NPKLKGILDKRYARVQLPDGKLGELVDMVSTIGFGVTGESARDILGQVYEYFLGQFASAE
CCCHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
GKRGGQFYTPASIVRTLVAILAPHHGQVYDPCCGSGGMFVQSEKFIEAHGGRIGDVSIYG
CCCCCCEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHCCCEEEEEEEEE
QESNPTTWRLAAMNLAIRGIDFNLGKEPADTFVRNQHPDLRADFVLANPPFNVSDWWHPS
CCCCCCEEEEEEEEEEEEEEECCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCC
LEGDPRWEYGTPPQGNANYAWLQHMLYHLKPTGRAGIVLANGSMSSSQNSEGEIRRALVE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
ADKVEVMVAMPGQLFFNTQIPACLWFLAKQKSVRQGEVLFIDARKLGTMISRVQIEFSDE
HCCEEEEEECCCCEEECCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHEEEEECHH
DIQRIADTVHAWRGDGEIPLNPPLPKGEAETIPPFTKGGPGGIYQDIPGFCRSVSLAEIA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHH
EHGHVLTPGRYVGAEAVEDDDEAFTEKMQRLTETLGEQMARGAELDELIRRKLGGLGYEF
HCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNPELIKTLWATADKLRANMDAAEYKHIVLGLIFVKYISDTFQTRSSELRERFGNPDDEY
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
YIQDADDETLVCELEDRDYYREVNTFWVPEAARWENIRAQAKQPDIGKRIDDALTLIEAE
EEECCCCCEEEEEECCCHHHHHCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHEEECC
NPKLKGILDKRYARVQLPDGKLGELVDMVSTIGFGVTGESARDILGQVYEYFLGQFASAE
CCCHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
GKRGGQFYTPASIVRTLVAILAPHHGQVYDPCCGSGGMFVQSEKFIEAHGGRIGDVSIYG
CCCCCCEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHCCCEEEEEEEEE
QESNPTTWRLAAMNLAIRGIDFNLGKEPADTFVRNQHPDLRADFVLANPPFNVSDWWHPS
CCCCCCEEEEEEEEEEEEEEECCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCC
LEGDPRWEYGTPPQGNANYAWLQHMLYHLKPTGRAGIVLANGSMSSSQNSEGEIRRALVE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
ADKVEVMVAMPGQLFFNTQIPACLWFLAKQKSVRQGEVLFIDARKLGTMISRVQIEFSDE
HCCEEEEEECCCCEEECCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHEEEEECHH
DIQRIADTVHAWRGDGEIPLNPPLPKGEAETIPPFTKGGPGGIYQDIPGFCRSVSLAEIA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHH
EHGHVLTPGRYVGAEAVEDDDEAFTEKMQRLTETLGEQMARGAELDELIRRKLGGLGYEF
HCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]