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The map label for this gene is fba [H]

Identifier: 118580273

GI number: 118580273

Start: 1992240

End: 1993310

Strand: Reverse

Name: fba [H]

Synonym: Ppro_1853

Alternate gene names: 118580273

Gene position: 1993310-1992240 (Counterclockwise)

Preceding gene: 118580274

Following gene: 118580272

Centisome position: 49.73

GC content: 63.49

Gene sequence:

>1071_bases
ATGTGCCTTTGGCCGGAAGGCGGGGTGCGAGGAAAGGGAGGAACCATGCCAGTTGCCGATTTAACGACCTACCGCCGGAT
GCTGGACCGGGCACGGGAGAACCGTTTTGCCTATCCGGCCATCAACGTAAGCTCACTGGCCACGGCCAACGCCGTGCTGC
GGGGCCTTGCCGAGGCCCGCTGTGACGGCATCATCCAGGTATCCACCGGGGGAGCGGCGTTTGCATCGGGCACCGCGCTC
AAGGATATGCCCCTGGGTGCCATCTCCATTGCCGAGCATGTCCACCGGGCCGCCCAGCGCTACCCCATCTATGTGGCACT
GCACACGGATCACTGCCCGGCCGACAAGCTGGACAGCTTCGTGCTACCGCTGGTGGCAGAGACGGAGCGGCGCCGGGCCG
CCGGGCTGCCCAACCTGTTCAACAGTCACATGTTCGACGGCAGCGCCCTCGCGCTCAAGGATAATCTGGATACGGCTACA
AGGCTTCTGGAGCGCTTCACGGCCTGTGAGCTGATCCTGGAGATCGAGACCGGCGTGGTGGGAGGCGAGGAGGATGGCAT
CAAGGCCGATGCCAGTGCCAAGCTCTACACCACCCCCGAGGAAACCCTGGAGGTGGCCAGGCGCCTCAACCCGCTGGGGG
GGCACTATCTTCTGGCCGCCACCTTCGGCAATGTCCACGGGGTCTACAAACCAGGCGCCGTCAAATTGCGGCCTTCGGTC
CTGAAGGAGTGTCAGGATGCGGTGGTCACACGCTACGGCGAAGCGGCACGTTTTCACCTTGTCTTCCATGGAGGCTCAGG
TTCGGAACTCCACGAGATCCGCGAGGCCCTGGATTACGGCGTGGTGAAGATGAACATCGACACCGACACCCAGTACGCCT
TCACCCGTCCCATCGCCGGCCACATGTTCAGCCACTATGACGGCGTGCTGAAGGTGGACGGAGACATGGGGGACAAGAAG
GCCTATGATCCCCGCACCTATCTGGCGCTGGCGGAAACAGCCATGGCCGAGCGGGTCAAGCGAGCGGTGAGCGATCTGCG
GGGGACCAACAGCACACTCTTCACGGGGTAA

Upstream 100 bases:

>100_bases
CTTCATTCAATTCACCGGACTATCATCTCTCTCAAACTGAATATCCAGCTGTCTTTCCGGGCGATCTTTGCGGGAACAGC
CGCTCTGGGAGAATGCTACA

Downstream 100 bases:

>100_bases
TTCGCCTGCCGTGATAGTGCCGCAACCAGAGAATCAGGAGGTGCATCGTGAAACTGCCAGACCACAAAACGAAAATCATC
TGCACCATCGGTCCGGCTTC

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MCLWPEGGVRGKGGTMPVADLTTYRRMLDRARENRFAYPAINVSSLATANAVLRGLAEARCDGIIQVSTGGAAFASGTAL
KDMPLGAISIAEHVHRAAQRYPIYVALHTDHCPADKLDSFVLPLVAETERRRAAGLPNLFNSHMFDGSALALKDNLDTAT
RLLERFTACELILEIETGVVGGEEDGIKADASAKLYTTPEETLEVARRLNPLGGHYLLAATFGNVHGVYKPGAVKLRPSV
LKECQDAVVTRYGEAARFHLVFHGGSGSELHEIREALDYGVVKMNIDTDTQYAFTRPIAGHMFSHYDGVLKVDGDMGDKK
AYDPRTYLALAETAMAERVKRAVSDLRGTNSTLFTG

Sequences:

>Translated_356_residues
MCLWPEGGVRGKGGTMPVADLTTYRRMLDRARENRFAYPAINVSSLATANAVLRGLAEARCDGIIQVSTGGAAFASGTAL
KDMPLGAISIAEHVHRAAQRYPIYVALHTDHCPADKLDSFVLPLVAETERRRAAGLPNLFNSHMFDGSALALKDNLDTAT
RLLERFTACELILEIETGVVGGEEDGIKADASAKLYTTPEETLEVARRLNPLGGHYLLAATFGNVHGVYKPGAVKLRPSV
LKECQDAVVTRYGEAARFHLVFHGGSGSELHEIREALDYGVVKMNIDTDTQYAFTRPIAGHMFSHYDGVLKVDGDMGDKK
AYDPRTYLALAETAMAERVKRAVSDLRGTNSTLFTG
>Mature_356_residues
MCLWPEGGVRGKGGTMPVADLTTYRRMLDRARENRFAYPAINVSSLATANAVLRGLAEARCDGIIQVSTGGAAFASGTAL
KDMPLGAISIAEHVHRAAQRYPIYVALHTDHCPADKLDSFVLPLVAETERRRAAGLPNLFNSHMFDGSALALKDNLDTAT
RLLERFTACELILEIETGVVGGEEDGIKADASAKLYTTPEETLEVARRLNPLGGHYLLAATFGNVHGVYKPGAVKLRPSV
LKECQDAVVTRYGEAARFHLVFHGGSGSELHEIREALDYGVVKMNIDTDTQYAFTRPIAGHMFSHYDGVLKVDGDMGDKK
AYDPRTYLALAETAMAERVKRAVSDLRGTNSTLFTG

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789293, Length=352, Percent_Identity=40.3409090909091, Blast_Score=241, Evalue=5e-65,
Organism=Escherichia coli, GI87082041, Length=325, Percent_Identity=25.2307692307692, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789526, Length=324, Percent_Identity=25.3086419753086, Blast_Score=81, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6322790, Length=348, Percent_Identity=36.4942528735632, Blast_Score=209, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006411
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38613; Mature: 38613

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLWPEGGVRGKGGTMPVADLTTYRRMLDRARENRFAYPAINVSSLATANAVLRGLAEAR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
CDGIIQVSTGGAAFASGTALKDMPLGAISIAEHVHRAAQRYPIYVALHTDHCPADKLDSF
CCCEEEEECCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
VLPLVAETERRRAAGLPNLFNSHMFDGSALALKDNLDTATRLLERFTACELILEIETGVV
HHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHEEEEEECCCC
GGEEDGIKADASAKLYTTPEETLEVARRLNPLGGHYLLAATFGNVHGVYKPGAVKLRPSV
CCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEECHHH
LKECQDAVVTRYGEAARFHLVFHGGSGSELHEIREALDYGVVKMNIDTDTQYAFTRPIAG
HHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCEEEECCHHH
HMFSHYDGVLKVDGDMGDKKAYDPRTYLALAETAMAERVKRAVSDLRGTNSTLFTG
HHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
>Mature Secondary Structure
MCLWPEGGVRGKGGTMPVADLTTYRRMLDRARENRFAYPAINVSSLATANAVLRGLAEAR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
CDGIIQVSTGGAAFASGTALKDMPLGAISIAEHVHRAAQRYPIYVALHTDHCPADKLDSF
CCCEEEEECCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
VLPLVAETERRRAAGLPNLFNSHMFDGSALALKDNLDTATRLLERFTACELILEIETGVV
HHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHEEEEEECCCC
GGEEDGIKADASAKLYTTPEETLEVARRLNPLGGHYLLAATFGNVHGVYKPGAVKLRPSV
CCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEECHHH
LKECQDAVVTRYGEAARFHLVFHGGSGSELHEIREALDYGVVKMNIDTDTQYAFTRPIAG
HHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCEEEECCHHH
HMFSHYDGVLKVDGDMGDKKAYDPRTYLALAETAMAERVKRAVSDLRGTNSTLFTG
HHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]