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The map label for this gene is fbp

Identifier: 118580196

GI number: 118580196

Start: 1904360

End: 1905331

Strand: Reverse

Name: fbp

Synonym: Ppro_1776

Alternate gene names: 118580196

Gene position: 1905331-1904360 (Counterclockwise)

Preceding gene: 118580197

Following gene: 118580195

Centisome position: 47.54

GC content: 57.0

Gene sequence:

>972_bases
ATGTTTGGCGAAGCGGGAAAAACCAAATTTCAGATCGATCTGCGGCAGCACCTCCGGGACCAGAATATCAGCGACAATCT
CGTGCATCTCATCTGCGAGATCGCCGAGGCCAGCAAATATGTTATCAACGCCATCCGTACCGGCGATCTGGGGGTGGCGG
GCACGTCAAACCTCTATGGCGAGGAGCAACTCGCCCTGGACGTGCTCTCCGACCGGATTATTCGCAAACGCCTGCAGCAC
TCCGGTGTTGTCTGCAACATCGCATCTGAAGAGATGGAGGAGATCTTCCAGGTTACCAGCAATCCCCAGGGGATGTTTTC
CGTTGCCTATGACCCCCTGGACGGTTCTTCCCTGGTGGACGTAAACCTGGCGGTCGGCACTATCGTGGGCATCTATCAGG
GAAGCGACCTGCTCCAACCGGGGCGCCACATGGTCGGCGCCATGTATATTCTCTACGGGCCACGCGTCTCCATGGTCTAT
TCGGTCGGCAAGGGGGTTTATGAATTCACCATGAACCAGCTGATGGAATTCACCCTCAGCCGCGAGCAGATACAGATGCA
CCCCTCGGGCGACATTTATTCCCCTGGCGGATTGCGCAAGAAGTACTGCGAGGGCAATGAACGTTTCATCCGCTACCTGG
AGGCAAAAGGCTCCAAGCTGCGCTATTCGGGCGGCTTCGTGCCGGACATCAATCAGGTGCTGATCAAGGGCAAGGGGGTA
TTCATGTATCCCGCCCTTACCGACAGCCCCAACGGCAAGCTGCGCCTTCTGTTCGAGCTCAATCCCATGGCTTTTTTGAT
CGAGCAGGCGGGTGGGGCAGCCACAAATGGACATATGCCGATTCTGGACATCGTTCCCGAAAGTCTGGACCAACGCTGTC
CCATTTACCTCGGGTGCCGTGATGACGTCGTGAAGGCGGCCGAGTTCCTGAATACCCCCTGCAAGACTCCCCACGAAGAG
CCGCAACCATGA

Upstream 100 bases:

>100_bases
GTTTACCCAAAACAGTCTTTGGGATTGCAATAGACAACGTATTACAGTATGTTTTTCTGTCGTATCCGGATAAATAATTC
AATGTATTTTGGAGGATGGC

Downstream 100 bases:

>100_bases
GCCTTGAAGAGCGCCCGTCGCAAGCGGGCCAGCAACTCCGGCGCCTGTGCAACGAGATTCAGCTTTTCGATCTGTGCGAC
CTGGAGCACTGCAGCTACAA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MFGEAGKTKFQIDLRQHLRDQNISDNLVHLICEIAEASKYVINAIRTGDLGVAGTSNLYGEEQLALDVLSDRIIRKRLQH
SGVVCNIASEEMEEIFQVTSNPQGMFSVAYDPLDGSSLVDVNLAVGTIVGIYQGSDLLQPGRHMVGAMYILYGPRVSMVY
SVGKGVYEFTMNQLMEFTLSREQIQMHPSGDIYSPGGLRKKYCEGNERFIRYLEAKGSKLRYSGGFVPDINQVLIKGKGV
FMYPALTDSPNGKLRLLFELNPMAFLIEQAGGAATNGHMPILDIVPESLDQRCPIYLGCRDDVVKAAEFLNTPCKTPHEE
PQP

Sequences:

>Translated_323_residues
MFGEAGKTKFQIDLRQHLRDQNISDNLVHLICEIAEASKYVINAIRTGDLGVAGTSNLYGEEQLALDVLSDRIIRKRLQH
SGVVCNIASEEMEEIFQVTSNPQGMFSVAYDPLDGSSLVDVNLAVGTIVGIYQGSDLLQPGRHMVGAMYILYGPRVSMVY
SVGKGVYEFTMNQLMEFTLSREQIQMHPSGDIYSPGGLRKKYCEGNERFIRYLEAKGSKLRYSGGFVPDINQVLIKGKGV
FMYPALTDSPNGKLRLLFELNPMAFLIEQAGGAATNGHMPILDIVPESLDQRCPIYLGCRDDVVKAAEFLNTPCKTPHEE
PQP
>Mature_323_residues
MFGEAGKTKFQIDLRQHLRDQNISDNLVHLICEIAEASKYVINAIRTGDLGVAGTSNLYGEEQLALDVLSDRIIRKRLQH
SGVVCNIASEEMEEIFQVTSNPQGMFSVAYDPLDGSSLVDVNLAVGTIVGIYQGSDLLQPGRHMVGAMYILYGPRVSMVY
SVGKGVYEFTMNQLMEFTLSREQIQMHPSGDIYSPGGLRKKYCEGNERFIRYLEAKGSKLRYSGGFVPDINQVLIKGKGV
FMYPALTDSPNGKLRLLFELNPMAFLIEQAGGAATNGHMPILDIVPESLDQRCPIYLGCRDDVVKAAEFLNTPCKTPHEE
PQP

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=314, Percent_Identity=35.9872611464968, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI189083692, Length=306, Percent_Identity=37.2549019607843, Blast_Score=177, Evalue=8e-45,
Organism=Homo sapiens, GI16579888, Length=306, Percent_Identity=37.2549019607843, Blast_Score=177, Evalue=8e-45,
Organism=Escherichia coli, GI1790679, Length=277, Percent_Identity=38.9891696750903, Blast_Score=182, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17508131, Length=316, Percent_Identity=39.5569620253165, Blast_Score=210, Evalue=9e-55,
Organism=Saccharomyces cerevisiae, GI6323409, Length=321, Percent_Identity=34.8909657320872, Blast_Score=169, Evalue=5e-43,
Organism=Drosophila melanogaster, GI45550998, Length=316, Percent_Identity=37.3417721518987, Blast_Score=178, Evalue=4e-45,
Organism=Drosophila melanogaster, GI19921562, Length=316, Percent_Identity=37.3417721518987, Blast_Score=178, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_PELPD (A1APW8)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901446.1
- ProteinModelPortal:   A1APW8
- SMR:   A1APW8
- STRING:   A1APW8
- GeneID:   4571536
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1776
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   HWEAPVQ
- PhylomeDB:   A1APW8
- ProtClustDB:   PRK09293
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR020548
- InterPro:   IPR023079
- PANTHER:   PTHR11556
- PRINTS:   PR01958

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 35775; Mature: 35775

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00124 FBPASE

Important sites: BINDING 222-222 BINDING 253-253

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGEAGKTKFQIDLRQHLRDQNISDNLVHLICEIAEASKYVINAIRTGDLGVAGTSNLYG
CCCCCCCEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
EEQLALDVLSDRIIRKRLQHSGVVCNIASEEMEEIFQVTSNPQGMFSVAYDPLDGSSLVD
CHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEE
VNLAVGTIVGIYQGSDLLQPGRHMVGAMYILYGPRVSMVYSVGKGVYEFTMNQLMEFTLS
EEEHHHHEEEEECCCCHHCCCHHHHHEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHC
REQIQMHPSGDIYSPGGLRKKYCEGNERFIRYLEAKGSKLRYSGGFVPDINQVLIKGKGV
HHHEEECCCCCEECCCCCCHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCHHHEEECCCE
FMYPALTDSPNGKLRLLFELNPMAFLIEQAGGAATNGHMPILDIVPESLDQRCPIYLGCR
EEEEEECCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCHHHHCCHHHCCCCCEEECCH
DDVVKAAEFLNTPCKTPHEEPQP
HHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFGEAGKTKFQIDLRQHLRDQNISDNLVHLICEIAEASKYVINAIRTGDLGVAGTSNLYG
CCCCCCCEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
EEQLALDVLSDRIIRKRLQHSGVVCNIASEEMEEIFQVTSNPQGMFSVAYDPLDGSSLVD
CHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEE
VNLAVGTIVGIYQGSDLLQPGRHMVGAMYILYGPRVSMVYSVGKGVYEFTMNQLMEFTLS
EEEHHHHEEEEECCCCHHCCCHHHHHEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHC
REQIQMHPSGDIYSPGGLRKKYCEGNERFIRYLEAKGSKLRYSGGFVPDINQVLIKGKGV
HHHEEECCCCCEECCCCCCHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCHHHEEECCCE
FMYPALTDSPNGKLRLLFELNPMAFLIEQAGGAATNGHMPILDIVPESLDQRCPIYLGCR
EEEEEECCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCHHHHCCHHHCCCCCEEECCH
DDVVKAAEFLNTPCKTPHEEPQP
HHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA