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The map label for this gene is ycjU [C]

Identifier: 118580169

GI number: 118580169

Start: 1880939

End: 1881622

Strand: Reverse

Name: ycjU [C]

Synonym: Ppro_1749

Alternate gene names: 118580169

Gene position: 1881622-1880939 (Counterclockwise)

Preceding gene: 118580170

Following gene: 118580157

Centisome position: 46.95

GC content: 60.96

Gene sequence:

>684_bases
ATGAACAACATGCAGGCAAGGGCGGTTATTTTCGATTTTGACGGCGTTATCGTGGATACGGAACCGCTGCACTACCGGGC
TTTTCAGCAGATCCTCGATCCGCGCGGTCTGGGCTTCAGCTGGCAGGAGTACGTGGAGACCTACATGGGCTTCGATGATC
GCGACGCATTCATGGAGGCGTTCAGCTCCCGAGGCGTCTCTCTGGAGGGCGGGGAACTGCAGCGGCTCATCGCCAGGAAA
GCCGACATATTCCAGGATGTCATCAAGGAAGGAATCAACGCCTACCCGGGCGTAGTCGAACTGATCAGGGACCTGCACAC
CGCGAAGGCCCCCCTGGCCATATGCAGCGGCGCCCTCAGGTCAGATATCATGCCCATCCTGGAGCTGCTCGGCATCAGCG
ACTGTTTCGATGTAATCGTGACCGCTGAGGATGTTGCCAGGAGCAAGCCGGACCCGGAGTGCTATCGGGTCTCCTTCGAC
AGGCTGAGGGAGTGCCGGTCTGAGTCGGAGTTCTGCACGACCGACACCATTGCCATCGAGGATACGCCGGCAGGCATCAG
CGCCGCCTCGTCGGCGGGCCTGCGGGTGATCGCGGTGACCAACAGCTATGCTGCCGGGCAATTGACCGCGGCGGACCGTA
TCGTGGAGTCGCTGGAACAGTTGCGGGGAGTCCACACGCCGTAA

Upstream 100 bases:

>100_bases
TCGTCACCGGCAGCCGCGCATTGGAAAACAGGTTCGCGGCCATCCCGCGACCTTCACATTACTGCGCCGGACTGGCGCTG
GCGACAACATGGTGACTTTT

Downstream 100 bases:

>100_bases
GAAGCAGCTCCCCTCTCATCTCCCGATACAGAAAGAGCCCTGAGGCCTTAAGCCCAGGGCTCTTTCTATGTGAAACATGG
GTCTCTATCCGACGGTCGGC

Product: HAD family hydrolase

Products: beta-D-glucose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MNNMQARAVIFDFDGVIVDTEPLHYRAFQQILDPRGLGFSWQEYVETYMGFDDRDAFMEAFSSRGVSLEGGELQRLIARK
ADIFQDVIKEGINAYPGVVELIRDLHTAKAPLAICSGALRSDIMPILELLGISDCFDVIVTAEDVARSKPDPECYRVSFD
RLRECRSESEFCTTDTIAIEDTPAGISAASSAGLRVIAVTNSYAAGQLTAADRIVESLEQLRGVHTP

Sequences:

>Translated_227_residues
MNNMQARAVIFDFDGVIVDTEPLHYRAFQQILDPRGLGFSWQEYVETYMGFDDRDAFMEAFSSRGVSLEGGELQRLIARK
ADIFQDVIKEGINAYPGVVELIRDLHTAKAPLAICSGALRSDIMPILELLGISDCFDVIVTAEDVARSKPDPECYRVSFD
RLRECRSESEFCTTDTIAIEDTPAGISAASSAGLRVIAVTNSYAAGQLTAADRIVESLEQLRGVHTP
>Mature_227_residues
MNNMQARAVIFDFDGVIVDTEPLHYRAFQQILDPRGLGFSWQEYVETYMGFDDRDAFMEAFSSRGVSLEGGELQRLIARK
ADIFQDVIKEGINAYPGVVELIRDLHTAKAPLAICSGALRSDIMPILELLGISDCFDVIVTAEDVARSKPDPECYRVSFD
RLRECRSESEFCTTDTIAIEDTPAGISAASSAGLRVIAVTNSYAAGQLTAADRIVESLEQLRGVHTP

Specific function: Displays high phosphatase activity toward erythrose 4- phosphate, fructose 6-phosphate, 2-deoxyglucose 6-phosphate, and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily [H]

Homologues:

Organism=Escherichia coli, GI87082080, Length=231, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1787576, Length=225, Percent_Identity=30.2222222222222, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789046, Length=191, Percent_Identity=24.0837696335079, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789787, Length=243, Percent_Identity=25.5144032921811, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788021, Length=219, Percent_Identity=24.6575342465753, Blast_Score=60, Evalue=9e-11,
Organism=Drosophila melanogaster, GI17137324, Length=232, Percent_Identity=28.0172413793103, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 5.4.2.6

Molecular weight: Translated: 25018; Mature: 25018

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNMQARAVIFDFDGVIVDTEPLHYRAFQQILDPRGLGFSWQEYVETYMGFDDRDAFMEA
CCCCCEEEEEEECCCEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHH
FSSRGVSLEGGELQRLIARKADIFQDVIKEGINAYPGVVELIRDLHTAKAPLAICSGALR
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SDIMPILELLGISDCFDVIVTAEDVARSKPDPECYRVSFDRLRECRSESEFCTTDTIAIE
HHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEC
DTPAGISAASSAGLRVIAVTNSYAAGQLTAADRIVESLEQLRGVHTP
CCCCCCCHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNNMQARAVIFDFDGVIVDTEPLHYRAFQQILDPRGLGFSWQEYVETYMGFDDRDAFMEA
CCCCCEEEEEEECCCEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHH
FSSRGVSLEGGELQRLIARKADIFQDVIKEGINAYPGVVELIRDLHTAKAPLAICSGALR
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SDIMPILELLGISDCFDVIVTAEDVARSKPDPECYRVSFDRLRECRSESEFCTTDTIAIE
HHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEC
DTPAGISAASSAGLRVIAVTNSYAAGQLTAADRIVESLEQLRGVHTP
CCCCCCCHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-D-glucose 1-phosphate

Specific reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate

General reaction: Group transfer (intramolecular phosphate group isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]