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The map label for this gene is fabF [H]

Identifier: 118580166

GI number: 118580166

Start: 1877775

End: 1879007

Strand: Direct

Name: fabF [H]

Synonym: Ppro_1746

Alternate gene names: 118580166

Gene position: 1877775-1879007 (Clockwise)

Preceding gene: 118580165

Following gene: 118580167

Centisome position: 46.85

GC content: 58.64

Gene sequence:

>1233_bases
ATGAGAAGAGTCGTCATTACGGGAGTTGGAACGGTTTCCTCCCTTGGCACCGGCAACAGCGCCAACTGGGATGCGCTGAC
CAGCGGCACTTGTGGTATCGGTCCGATAACCCGCTTCGATGCATCTGATATTCCGGTAAAGATCGCAGGCGAAGTTAAGG
GTTTCAATGCCGAGGACTTCTTTGACAAGAAAGAAGCCAAGAAGATGGATCTGTTCATCCAGTACGCCATGGCTGCCGCC
CAGTTTGCCATGACCGATTCCGGCCTTGTCGTGAACGAGGAGAATGCCGAGCGCGTGGGTGTCCTGGTCGGTTCCGGCCT
GGGCGGTCTGCCCACCATCGAGAAATACCACATCGCCATGATGGAGGGGGGCGTCAAGAAAATCTCTCCTTTCTTTATCC
CCATGCTGCTGATCAACCTTGCCCCCGGCATGATCTCCATCAAATACGGTGCCAAGGGTCCCAATATATCCTCCGTCTCC
GCCTGTGCCACCGGCACTCATTCCATTGGCGACGCCTTTCACATCATCAAGCGCGGCGATGCCGACGCCATGATAGCAGG
CGGCACGGAATCAACGATCACCCCCCTGGCCGTGGGCGGTTTTGCCGCCATGAAGGCGCTCTCCACCCGAAACGATGCCC
CGGAGAAGGCCTCGCGCCCCTTTGACAAGGATCGTGACGGTTTCATCATGGCCGAGGGTGCTGGCATCGTGGTCATGGAG
GAATACGAATCCGCCAAGAAACGCGGCGCCAGGATCTACGCCGAGGTTGTCGGCTACGGCCTGAGCGGTGACGCCTATCA
CATGACCGCGCCTGCTGCCGGCGGCGAGGGGGCCGCGCGCTGCATGAAGATGGCCCTGAACAACGCCGGCGTCAGCCCTG
ACCAGGTGACCTATATCAATGCCCATGGCACTTCCACGCCGTTCAACGACCTGAACGAGACCCTTGCCATCAAGTCGGTC
TTCGGTGGTCACGCCTCGAAACTGATGGTCTCTTCCACCAAGTCCATGACTGGCCACCTGCTGGGCGCCGCTGGCGGGAT
CGAGGCCGCGATTTGCTGCATGGCCATGGACAAGGGAGTCGTCCCGCCGACCATTAACTACGAGACGCCTGATCCTGAGT
TGGATCTGGACTATGTCCCCAACACCGCCCGCAACGCTAGTATTGAATATGCCATGAGCAATTCACTCGGTTTCGGCGGT
ACCAACGCAACGCTTCTGTTCAAGAAGATCTAG

Upstream 100 bases:

>100_bases
ACCTTGGAGAGGGAGAGGGGACTAGCTCCCCTCTTTCTCGTTTTTGCCTTTCTTTTTCATATCGATGTACCACAACAGTA
TAATCTGGGAGTCATACATT

Downstream 100 bases:

>100_bases
TCGGGGGATCTCTCATGATTGTAATTGGCAGCGATCACGGCGGGCTTGACCTCAAGCAGGCGCTGACGCGCTACCTGGCC
GATCGCGCTATCAAAGTCAG

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MRRVVITGVGTVSSLGTGNSANWDALTSGTCGIGPITRFDASDIPVKIAGEVKGFNAEDFFDKKEAKKMDLFIQYAMAAA
QFAMTDSGLVVNEENAERVGVLVGSGLGGLPTIEKYHIAMMEGGVKKISPFFIPMLLINLAPGMISIKYGAKGPNISSVS
ACATGTHSIGDAFHIIKRGDADAMIAGGTESTITPLAVGGFAAMKALSTRNDAPEKASRPFDKDRDGFIMAEGAGIVVME
EYESAKKRGARIYAEVVGYGLSGDAYHMTAPAAGGEGAARCMKMALNNAGVSPDQVTYINAHGTSTPFNDLNETLAIKSV
FGGHASKLMVSSTKSMTGHLLGAAGGIEAAICCMAMDKGVVPPTINYETPDPELDLDYVPNTARNASIEYAMSNSLGFGG
TNATLLFKKI

Sequences:

>Translated_410_residues
MRRVVITGVGTVSSLGTGNSANWDALTSGTCGIGPITRFDASDIPVKIAGEVKGFNAEDFFDKKEAKKMDLFIQYAMAAA
QFAMTDSGLVVNEENAERVGVLVGSGLGGLPTIEKYHIAMMEGGVKKISPFFIPMLLINLAPGMISIKYGAKGPNISSVS
ACATGTHSIGDAFHIIKRGDADAMIAGGTESTITPLAVGGFAAMKALSTRNDAPEKASRPFDKDRDGFIMAEGAGIVVME
EYESAKKRGARIYAEVVGYGLSGDAYHMTAPAAGGEGAARCMKMALNNAGVSPDQVTYINAHGTSTPFNDLNETLAIKSV
FGGHASKLMVSSTKSMTGHLLGAAGGIEAAICCMAMDKGVVPPTINYETPDPELDLDYVPNTARNASIEYAMSNSLGFGG
TNATLLFKKI
>Mature_410_residues
MRRVVITGVGTVSSLGTGNSANWDALTSGTCGIGPITRFDASDIPVKIAGEVKGFNAEDFFDKKEAKKMDLFIQYAMAAA
QFAMTDSGLVVNEENAERVGVLVGSGLGGLPTIEKYHIAMMEGGVKKISPFFIPMLLINLAPGMISIKYGAKGPNISSVS
ACATGTHSIGDAFHIIKRGDADAMIAGGTESTITPLAVGGFAAMKALSTRNDAPEKASRPFDKDRDGFIMAEGAGIVVME
EYESAKKRGARIYAEVVGYGLSGDAYHMTAPAAGGEGAARCMKMALNNAGVSPDQVTYINAHGTSTPFNDLNETLAIKSV
FGGHASKLMVSSTKSMTGHLLGAAGGIEAAICCMAMDKGVVPPTINYETPDPELDLDYVPNTARNASIEYAMSNSLGFGG
TNATLLFKKI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=415, Percent_Identity=48.9156626506024, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI223972627, Length=146, Percent_Identity=54.7945205479452, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI41872631, Length=278, Percent_Identity=26.978417266187, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1787337, Length=410, Percent_Identity=55.3658536585366, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1788663, Length=415, Percent_Identity=40.9638554216867, Blast_Score=263, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71983541, Length=415, Percent_Identity=37.3493975903614, Blast_Score=263, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI71983535, Length=259, Percent_Identity=43.2432432432432, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI212642053, Length=412, Percent_Identity=26.6990291262136, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=412, Percent_Identity=21.6019417475728, Blast_Score=95, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6320904, Length=444, Percent_Identity=38.963963963964, Blast_Score=276, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24644341, Length=415, Percent_Identity=42.8915662650602, Blast_Score=330, Evalue=9e-91,
Organism=Drosophila melanogaster, GI19920632, Length=383, Percent_Identity=24.0208877284595, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI221330659, Length=383, Percent_Identity=24.0208877284595, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24581345, Length=382, Percent_Identity=25.130890052356, Blast_Score=109, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42753; Mature: 42753

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVVITGVGTVSSLGTGNSANWDALTSGTCGIGPITRFDASDIPVKIAGEVKGFNAEDF
CCEEEEEECCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHH
FDKKEAKKMDLFIQYAMAAAQFAMTDSGLVVNEENAERVGVLVGSGLGGLPTIEKYHIAM
HCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCCHHEEEEE
MEGGVKKISPFFIPMLLINLAPGMISIKYGAKGPNISSVSACATGTHSIGDAFHIIKRGD
ECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHCCCCCCCCCCEEEEECCC
ADAMIAGGTESTITPLAVGGFAAMKALSTRNDAPEKASRPFDKDRDGFIMAEGAGIVVME
CCEEEECCCCCCCCCEEHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEECCCCEEEEC
EYESAKKRGARIYAEVVGYGLSGDAYHMTAPAAGGEGAARCMKMALNNAGVSPDQVTYIN
CHHHHHHHCCEEEEHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEE
AHGTSTPFNDLNETLAIKSVFGGHASKLMVSSTKSMTGHLLGAAGGIEAAICCMAMDKGV
CCCCCCCHHHHHHHEEHHHHHCCCCCEEEEECCHHHHHEEEECCCCHHHHHHHHHHCCCC
VPPTINYETPDPELDLDYVPNTARNASIEYAMSNSLGFGGTNATLLFKKI
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MRRVVITGVGTVSSLGTGNSANWDALTSGTCGIGPITRFDASDIPVKIAGEVKGFNAEDF
CCEEEEEECCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHH
FDKKEAKKMDLFIQYAMAAAQFAMTDSGLVVNEENAERVGVLVGSGLGGLPTIEKYHIAM
HCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCCCCHHEEEEE
MEGGVKKISPFFIPMLLINLAPGMISIKYGAKGPNISSVSACATGTHSIGDAFHIIKRGD
ECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHCCCCCCCCCCEEEEECCC
ADAMIAGGTESTITPLAVGGFAAMKALSTRNDAPEKASRPFDKDRDGFIMAEGAGIVVME
CCEEEECCCCCCCCCEEHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEECCCCEEEEC
EYESAKKRGARIYAEVVGYGLSGDAYHMTAPAAGGEGAARCMKMALNNAGVSPDQVTYIN
CHHHHHHHCCEEEEHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEE
AHGTSTPFNDLNETLAIKSVFGGHASKLMVSSTKSMTGHLLGAAGGIEAAICCMAMDKGV
CCCCCCCHHHHHHHEEHHHHHCCCCCEEEEECCHHHHHEEEECCCCHHHHHHHHHHCCCC
VPPTINYETPDPELDLDYVPNTARNASIEYAMSNSLGFGGTNATLLFKKI
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]