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The map label for this gene is clpB2 [H]

Identifier: 118580157

GI number: 118580157

Start: 1868804

End: 1871425

Strand: Reverse

Name: clpB2 [H]

Synonym: Ppro_1737

Alternate gene names: 118580157

Gene position: 1871425-1868804 (Counterclockwise)

Preceding gene: 118580169

Following gene: 118580156

Centisome position: 46.69

GC content: 63.62

Gene sequence:

>2622_bases
ATGGACATAAACCGGTTGACACAGAAATCCCAGGAAGCGTTCGCGGAAGCGCAGAGCAAGGCGGTAACCTACGGCCACGT
GGAGGTGGATGGCGAGCACCTGCTCTGGTCGCTGGTGAACCAGGCCGACGGGCTGGTCCCCCGCCTGCTGCGGCGCATGG
ATATCAGGCCTGAACACTTGGAGAAGGAGATCGAAGGGGAACTGGAGCGGCGGCCCCGCGTGTCCGGACCGGGAGCGGAA
CCGGGCAAGATCTACGTCTCACAGCGCCTCTCCCGCATCCTGGTGGAGGCGGAAAACGAGGCAAAACGGCTCAAAGACGA
GTACGTCTCCGTGGAGCACCTGCTGATGGCCCTGGTGGCCGAGGGGGACAAGAGCCCTGCCGGCAGGCTGCTGAAGCAGG
TTGGCCTGGAAAGAGAGAAGCTGCTCAAGGCGCTCACCGACGTGCGTGGCAACCAGCGGGTGCAGAGCCAGAACCCCGAG
GCCAGCTACGAGGCGCTGGAGAAGTACGGCCGCGACCTGGTAAAGCAGGCCAGGAGCGGCAAGCTTGACCCGGTCATCGG
CCGGGACGAGGACATCCGCCGGGTGATCCGCATCCTCTCCCGCAAGACCAAGAACAACCCGGTGCTGATTGGCGAACCGG
GTGTGGGCAAGACCGCCATCGTGGAGGGACTGGCCCAGCGCATCGTGCGCGGCGACGTCCCTGAAGGGTTGAAGAAGAAG
ACCATCTTCGCACTGGACATGGGATCGCTCATCGCCGGGGCCAAGTACCGCGGCGAGTTCGAGGAGCGACTGAAGGCGGT
GCTCAACGAGGTCAAGGAGGGAGAGGGGCGCATCATCCTCTTCATCGACGAACTGCACACCATCGTCGGCGCCGGCAAGG
CCGAAGGGGCCATGGATGCCGGCAACATGCTCAAGCCGATGCTGGCCCGGGGTGAGTTGCACTGCATCGGCGCCACCACC
CTGGACGAGTACCGCCAACATATCGAGAAAGACGCTGCCCTGGAACGGCGCTTCCAGCCGGTGCTGGTGGAGCAGCCCAC
GGTGGAGGACACGGTCTCCATCCTGCGCGGCCTGCGTGAGCGCTTCGAGGTGCACCACGGCATCAAGATACAGGACTCGG
CCCTGGTGGCGGCGGCAACCCTCTCCAACCGCTACATCACCGAACGTTTCCTGCCGGACAAGGCCATCGACCTGGTGGAC
GAAGCCTGCGCCATGCTGCGCACGGAGATCGACTCCCTGCCGTCTGAACTGGACACCATCAACCGTCGGGTGATGCAGCT
GGAGATCGAGGAGGTGGCCCTGAAGAAGGAGAAGGACCGCGCCAGCCAGGAGCGGCTGAAGGCTCTGCGCAGGGAACTGG
CCGACGACCGGGAACGGGCCAACGCCATGCGTGCCCAGTACGAAACGGAGAAGTGCGCCATCCAGCGCATCCAGGGTCTA
CGAGAGCAGATCGAGAAGACCCGCCACGACATCGAACAGGCCGAGCGGGACAGCAACCTGGAACTGGCCTCAAAACTGAA
GTACTCGGAGATGCCCGGCTTGGAGAAGGCTCTGCACAACGAGGAGGCCACCCTGGCCGCCAACCAGGGAGGACAGAAGC
TGCTCAGGGAAGAGGTGACCGAGGACGAGATCGCCCAGATCGTGGCCAACTGGACCGGCATACCGGTCATGCGGCTGGTG
GAGGGGGAGCGGGAGAAGCTGCTCCGGCTGGAGGACATCCTGCACCAGCGGGTCATCGGCCAGGACGAGGCGGTGCGTCT
GGTTTCCGATGCCGTGCTCAGAGCCCGCTCCGGCATCAAGGACCCGCACCGCCCCATTGGTTCGTTCATTTTTCTGGGCC
CCACCGGTGTGGGCAAGACCGAGCTGGCCCGCACCCTGGCCGAGGCGCTGTTCGACTCGGAAGACAACATGGTGCGCATC
GACATGTCGGAATACATGGAGAAGTTCGCCGTATCGCGCCTGATCGGCGCTCCTCCCGGCTACGTGGGGTACGAGGAGGG
GGGGCAGCTGACCGAGGCGGTGCGGCGCAAACCGTACTGTGTGCTCCTCTTCGACGAGATCGAAAAGGCCCACCCGGATG
TGTTCAACATCCTGCTGCAGATCCTGGACGACGGCCGGGTCACGGACAGCCACGGCAGGACAGTGAACTTCAAGAACACG
GTTATCATCATGACCTCCAACATCGGTGCGCCGCACCTGATCGAGGGTATCACCCCTGAGGGGGATATCCGCGACAATGC
CCGCAGGATGGTGATGAACGAGCTCAGGGCAGGATTCCGCCCCGAATTTCTCAACCGTGTGGACGACATCGTGCTCTTCA
AGCCGCTGCATCCGGACGAGATCGTCAAGATCACCGACCTTTTGGCACAGCAGCTGATTCTGCGCCTCAGGGAGCGCCAG
ATAACCCTCACCTTAAGCGACGAGGCAAAGCGCTTCATCGCCACGAGCGGCTACGACCCGGTCTACGGCGCCCGCCCGCT
GAAGCGCTTCCTGCAGCGTGAACTGGAGACCAGAGTAGCCCGAGCGATCATCGGCGGAACAATAGCCGAGGGGGGCGAAC
TGCGGGTGGACCTGAGGGATGGTGAACTCGTGCTGGAGGCGGGAATTCAGACCTCATCGTAA

Upstream 100 bases:

>100_bases
TTAACTGAAGCGAAACGTTGAATCCCCTCTCAAGCGGGATGGGTTGGCGTGGCTCACGAAGTGGGGACAGTTTTTCGGAA
CTAAAAGAGAGGAATTGGAT

Downstream 100 bases:

>100_bases
GCTGATCCTTCTTCCCCTTCAAAGGGAGGAATAAAAGGAGAGAAAGCCGGGGAGTGACGGATGTCGATCCCCGGCTTTTG
TCATACAGAGTTGCCATGGT

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 873; Mature: 873

Protein sequence:

>873_residues
MDINRLTQKSQEAFAEAQSKAVTYGHVEVDGEHLLWSLVNQADGLVPRLLRRMDIRPEHLEKEIEGELERRPRVSGPGAE
PGKIYVSQRLSRILVEAENEAKRLKDEYVSVEHLLMALVAEGDKSPAGRLLKQVGLEREKLLKALTDVRGNQRVQSQNPE
ASYEALEKYGRDLVKQARSGKLDPVIGRDEDIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRGDVPEGLKKK
TIFALDMGSLIAGAKYRGEFEERLKAVLNEVKEGEGRIILFIDELHTIVGAGKAEGAMDAGNMLKPMLARGELHCIGATT
LDEYRQHIEKDAALERRFQPVLVEQPTVEDTVSILRGLRERFEVHHGIKIQDSALVAAATLSNRYITERFLPDKAIDLVD
EACAMLRTEIDSLPSELDTINRRVMQLEIEEVALKKEKDRASQERLKALRRELADDRERANAMRAQYETEKCAIQRIQGL
REQIEKTRHDIEQAERDSNLELASKLKYSEMPGLEKALHNEEATLAANQGGQKLLREEVTEDEIAQIVANWTGIPVMRLV
EGEREKLLRLEDILHQRVIGQDEAVRLVSDAVLRARSGIKDPHRPIGSFIFLGPTGVGKTELARTLAEALFDSEDNMVRI
DMSEYMEKFAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYCVLLFDEIEKAHPDVFNILLQILDDGRVTDSHGRTVNFKNT
VIIMTSNIGAPHLIEGITPEGDIRDNARRMVMNELRAGFRPEFLNRVDDIVLFKPLHPDEIVKITDLLAQQLILRLRERQ
ITLTLSDEAKRFIATSGYDPVYGARPLKRFLQRELETRVARAIIGGTIAEGGELRVDLRDGELVLEAGIQTSS

Sequences:

>Translated_873_residues
MDINRLTQKSQEAFAEAQSKAVTYGHVEVDGEHLLWSLVNQADGLVPRLLRRMDIRPEHLEKEIEGELERRPRVSGPGAE
PGKIYVSQRLSRILVEAENEAKRLKDEYVSVEHLLMALVAEGDKSPAGRLLKQVGLEREKLLKALTDVRGNQRVQSQNPE
ASYEALEKYGRDLVKQARSGKLDPVIGRDEDIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRGDVPEGLKKK
TIFALDMGSLIAGAKYRGEFEERLKAVLNEVKEGEGRIILFIDELHTIVGAGKAEGAMDAGNMLKPMLARGELHCIGATT
LDEYRQHIEKDAALERRFQPVLVEQPTVEDTVSILRGLRERFEVHHGIKIQDSALVAAATLSNRYITERFLPDKAIDLVD
EACAMLRTEIDSLPSELDTINRRVMQLEIEEVALKKEKDRASQERLKALRRELADDRERANAMRAQYETEKCAIQRIQGL
REQIEKTRHDIEQAERDSNLELASKLKYSEMPGLEKALHNEEATLAANQGGQKLLREEVTEDEIAQIVANWTGIPVMRLV
EGEREKLLRLEDILHQRVIGQDEAVRLVSDAVLRARSGIKDPHRPIGSFIFLGPTGVGKTELARTLAEALFDSEDNMVRI
DMSEYMEKFAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYCVLLFDEIEKAHPDVFNILLQILDDGRVTDSHGRTVNFKNT
VIIMTSNIGAPHLIEGITPEGDIRDNARRMVMNELRAGFRPEFLNRVDDIVLFKPLHPDEIVKITDLLAQQLILRLRERQ
ITLTLSDEAKRFIATSGYDPVYGARPLKRFLQRELETRVARAIIGGTIAEGGELRVDLRDGELVLEAGIQTSS
>Mature_873_residues
MDINRLTQKSQEAFAEAQSKAVTYGHVEVDGEHLLWSLVNQADGLVPRLLRRMDIRPEHLEKEIEGELERRPRVSGPGAE
PGKIYVSQRLSRILVEAENEAKRLKDEYVSVEHLLMALVAEGDKSPAGRLLKQVGLEREKLLKALTDVRGNQRVQSQNPE
ASYEALEKYGRDLVKQARSGKLDPVIGRDEDIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRGDVPEGLKKK
TIFALDMGSLIAGAKYRGEFEERLKAVLNEVKEGEGRIILFIDELHTIVGAGKAEGAMDAGNMLKPMLARGELHCIGATT
LDEYRQHIEKDAALERRFQPVLVEQPTVEDTVSILRGLRERFEVHHGIKIQDSALVAAATLSNRYITERFLPDKAIDLVD
EACAMLRTEIDSLPSELDTINRRVMQLEIEEVALKKEKDRASQERLKALRRELADDRERANAMRAQYETEKCAIQRIQGL
REQIEKTRHDIEQAERDSNLELASKLKYSEMPGLEKALHNEEATLAANQGGQKLLREEVTEDEIAQIVANWTGIPVMRLV
EGEREKLLRLEDILHQRVIGQDEAVRLVSDAVLRARSGIKDPHRPIGSFIFLGPTGVGKTELARTLAEALFDSEDNMVRI
DMSEYMEKFAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYCVLLFDEIEKAHPDVFNILLQILDDGRVTDSHGRTVNFKNT
VIIMTSNIGAPHLIEGITPEGDIRDNARRMVMNELRAGFRPEFLNRVDDIVLFKPLHPDEIVKITDLLAQQLILRLRERQ
ITLTLSDEAKRFIATSGYDPVYGARPLKRFLQRELETRVARAIIGGTIAEGGELRVDLRDGELVLEAGIQTSS

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=323, Percent_Identity=34.6749226006192, Blast_Score=199, Evalue=1e-50,
Organism=Escherichia coli, GI1788943, Length=864, Percent_Identity=54.1666666666667, Blast_Score=916, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=337, Percent_Identity=41.839762611276, Blast_Score=273, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6320464, Length=714, Percent_Identity=52.3809523809524, Blast_Score=744, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=876, Percent_Identity=41.0958904109589, Blast_Score=647, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 98210; Mature: 98210

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINRLTQKSQEAFAEAQSKAVTYGHVEVDGEHLLWSLVNQADGLVPRLLRRMDIRPEHL
CCCHHHHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHHCCHHHHHHHHCCCCHHHH
EKEIEGELERRPRVSGPGAEPGKIYVSQRLSRILVEAENEAKRLKDEYVSVEHLLMALVA
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGDKSPAGRLLKQVGLEREKLLKALTDVRGNQRVQSQNPEASYEALEKYGRDLVKQARSG
CCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
KLDPVIGRDEDIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRGDVPEGLKKK
CCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHC
TIFALDMGSLIAGAKYRGEFEERLKAVLNEVKEGEGRIILFIDELHTIVGAGKAEGAMDA
EEEEEEHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCC
GNMLKPMLARGELHCIGATTLDEYRQHIEKDAALERRFQPVLVEQPTVEDTVSILRGLRE
HHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
RFEVHHGIKIQDSALVAAATLSNRYITERFLPDKAIDLVDEACAMLRTEIDSLPSELDTI
HHHHHCCCEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRRVMQLEIEEVALKKEKDRASQERLKALRRELADDRERANAMRAQYETEKCAIQRIQGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REQIEKTRHDIEQAERDSNLELASKLKYSEMPGLEKALHNEEATLAANQGGQKLLREEVT
HHHHHHHHHHHHHHHCCCCCHHHHHHCHHCCCCHHHHHCCCCCEEECCCCHHHHHHHHCC
EDEIAQIVANWTGIPVMRLVEGEREKLLRLEDILHQRVIGQDEAVRLVSDAVLRARSGIK
HHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
DPHRPIGSFIFLGPTGVGKTELARTLAEALFDSEDNMVRIDMSEYMEKFAVSRLIGAPPG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCC
YVGYEEGGQLTEAVRRKPYCVLLFDEIEKAHPDVFNILLQILDDGRVTDSHGRTVNFKNT
CCCCCCCCHHHHHHHCCCEEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEECCE
VIIMTSNIGAPHLIEGITPEGDIRDNARRMVMNELRAGFRPEFLNRVDDIVLFKPLHPDE
EEEEECCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCHHH
IVKITDLLAQQLILRLRERQITLTLSDEAKRFIATSGYDPVYGARPLKRFLQRELETRVA
HHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
RAIIGGTIAEGGELRVDLRDGELVLEAGIQTSS
HHHHHCCCCCCCEEEEEECCCCEEEECCCCCCC
>Mature Secondary Structure
MDINRLTQKSQEAFAEAQSKAVTYGHVEVDGEHLLWSLVNQADGLVPRLLRRMDIRPEHL
CCCHHHHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHHCCHHHHHHHHCCCCHHHH
EKEIEGELERRPRVSGPGAEPGKIYVSQRLSRILVEAENEAKRLKDEYVSVEHLLMALVA
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGDKSPAGRLLKQVGLEREKLLKALTDVRGNQRVQSQNPEASYEALEKYGRDLVKQARSG
CCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
KLDPVIGRDEDIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRGDVPEGLKKK
CCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHC
TIFALDMGSLIAGAKYRGEFEERLKAVLNEVKEGEGRIILFIDELHTIVGAGKAEGAMDA
EEEEEEHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCC
GNMLKPMLARGELHCIGATTLDEYRQHIEKDAALERRFQPVLVEQPTVEDTVSILRGLRE
HHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
RFEVHHGIKIQDSALVAAATLSNRYITERFLPDKAIDLVDEACAMLRTEIDSLPSELDTI
HHHHHCCCEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRRVMQLEIEEVALKKEKDRASQERLKALRRELADDRERANAMRAQYETEKCAIQRIQGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REQIEKTRHDIEQAERDSNLELASKLKYSEMPGLEKALHNEEATLAANQGGQKLLREEVT
HHHHHHHHHHHHHHHCCCCCHHHHHHCHHCCCCHHHHHCCCCCEEECCCCHHHHHHHHCC
EDEIAQIVANWTGIPVMRLVEGEREKLLRLEDILHQRVIGQDEAVRLVSDAVLRARSGIK
HHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
DPHRPIGSFIFLGPTGVGKTELARTLAEALFDSEDNMVRIDMSEYMEKFAVSRLIGAPPG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCC
YVGYEEGGQLTEAVRRKPYCVLLFDEIEKAHPDVFNILLQILDDGRVTDSHGRTVNFKNT
CCCCCCCCHHHHHHHCCCEEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEECCE
VIIMTSNIGAPHLIEGITPEGDIRDNARRMVMNELRAGFRPEFLNRVDDIVLFKPLHPDE
EEEEECCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCHHH
IVKITDLLAQQLILRLRERQITLTLSDEAKRFIATSGYDPVYGARPLKRFLQRELETRVA
HHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
RAIIGGTIAEGGELRVDLRDGELVLEAGIQTSS
HHHHHCCCCCCCEEEEEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]