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The map label for this gene is cheA [H]

Identifier: 118580030

GI number: 118580030

Start: 1720367

End: 1722490

Strand: Direct

Name: cheA [H]

Synonym: Ppro_1607

Alternate gene names: 118580030

Gene position: 1720367-1722490 (Clockwise)

Preceding gene: 118580029

Following gene: 118580031

Centisome position: 42.92

GC content: 60.12

Gene sequence:

>2124_bases
ATGATGGAACAAGCCATAGCAACCTACCGTGAGGAGGCCAGTGAGCTGTTAGCAGAACTGGAGAGCTCGCTTCTGGAACT
GGAGGACACGCCGGACGACGATGACCTTATTAATCGCGTCTTCCGCGCCATGCACACCATCAAGGGTTCCGGCGCCATGT
TCGGGTTCGACGAGATAGCCTCATTCACCCACGAGGTGGAGACGGTCTTCGACATGGTACGCAATGGGAAGATGAGCGTG
ACCAAGCGCCTGCTTGACCTGACCCTCAGGTCGCGGGACCATATCTTGGCGCTTTTGGATGCTTCCGCCGGTTCGGGGGA
GGTTGACCGCAGCCAGGGCGACGAGATCATAGCCAGTCTGCAGCAGTTGCTGCCGCAGGCCGTGGGAGGTGGCGGCGAAG
TAGAGGCGGCGCCCAGTCAGAGTGAGTCTGGCGAAGCTGAGGCTACCGAGGAAAAAACCTGGCGTATCCGCTTTCGCCCC
ACTCGCGAACTGCTGCTGTTCGGTACCAATCCGGTCTCTCTGATCAATGAACTGCGCAGTCTGGGGGAGTGCCATGTGGT
GGCCCAGTTGGACGAGATCCCGCTGCTTGACGACCTGACGGCGGAACACTGCTATCTGTACTGGGATATCATCCTGACCA
GCACTCGTGGCGAAGATGCCATCAAGGACGTGTTCATCTTCGTAGAGGATGACTGCGATATCAAGATCCAGCTGATCGAC
AGCGGTGGCCTGATCGACCGTGAGGATGGCTACAAGAAGCTGGGTCACATCCTGGTGGAGCGTGGCGACCTCTCCGTCGA
GGAGATGCAGACGGTTTTAACCCAGCAGAAGCGCTTTGGAGAGCTGCTGGTGGAGCAGGGAATTGTCGACCCCGAGAAGG
TCCAGTCGGCCCTGATTGAGCAGCAGCACGTCAAGGCCGTGCGTCAGGAGCGGAGCGCCGCTCCCCAGGCGGATGCCGCT
GCCAGTATCCGTGTCCCTGCCGAACGGCTGGATCAGCTGATCAACCTGGTGGGGGAGATGGTCACGGTGCAAGCCCGGCT
TTCCCAGGTTTCATTGGCTTGTGGCGATGCCACCTTCATTTCCATCTCCGAAGAGGTGGAGCGACTCACCAACGAGTTGC
GCGATACGGCCCTGAACATCCGTATGCTGCCTATAGGCAGTACCTTCAGTAAGTTCAAACGACTGGTGCGCGACCTTTCC
CAGGAACTGGGCAAGGAAATCGAGATGGAGACTTTCGGGGCCGAGACCGAACTGGACAAGACCGTCATCGAAAAGCTGAA
CGACCCGCTGGTGCATATCATCCGCAACAGCATCGACCACGGCATCGAGATGCCCGATGTTCGGCGGGCCGCCGGAAAGC
CCTCCGTCGGCACCGTCTGCCTGGGGGCCGTACATTCCGGCGACTCGGTTCTGATAACCATCCGTGATGACGGTGCCGGC
CTGGACCGGGACACTATCCGCGCCAAGGCTGTTGAGCGGGGCCTTCTGGCCGCCACTGCCGAGGTGTCCGACAAGGAAAT
CTATTCGCAGATCTTTGCCCCCGGGTTCTCCACCGCGCAGAAGATCACCAACATCTCCGGCCGTGGTGTTGGCATGGATG
TGGTTAAACGCGGCATCCAGGATCTGCGTGGCACCATCGAAGTTGACAGCGTGCGGGGAAGCGGCACCACCATCACCCTG
CGGATTCCCCTGACCCTGGCCATCATCGAGAGTCTGCTGGTCAAGATCGGCGACAGCCACTTCGTACTGCCCCTGGCCGC
GGTGGAGGAGTGCGTGGAACTGACCCGGGAGGATGTGGAGGCAGCCCATGGACGCAACCTGGCAATCATCAGGGGCAATC
TCACGCCGTTCATCTCGCTGCGGGAACAGTTCGAGATTGACGGTGATCGTCCTGATATCGAGCAGATCGTGATCGTCTCG
GTGAATGGGATGCGCATCGGATTCGTGGTCGATTTTGTGGTTGGCGAGCACCAGACCGTGATCAAACCGCTGGGGCGGTT
ATACCAGGACATCAAGGGGGTATCGGGCGCCACCATCCTGGGCGACGGTTCCGTGGCCCTGATCCTCGACCCCGGCGTGT
TGACCCAGTGCGCCGAAATGGCCGAGGCCAGCCTGACTCAGTGA

Upstream 100 bases:

>100_bases
GAAAATCTGGTGAGGAGTGAAGGGCAAAGAGTGAGGCCATACCCCTTTATTCCCCACCAGTTTTTTCTTCACCTCTTACC
CACACACCGAGGTGTTATTT

Downstream 100 bases:

>100_bases
TGTCCTGGCGACGAGTCGCTCGGAAGGGGCATCATCGTTCGCCATGTTTCTGCAAACCGCACCGCTTCAAGTGGTAACGA
TAAAGGCCAAAAAGCAAGCA

Product: signal transduction histidine kinase CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 707

Protein sequence:

>707_residues
MMEQAIATYREEASELLAELESSLLELEDTPDDDDLINRVFRAMHTIKGSGAMFGFDEIASFTHEVETVFDMVRNGKMSV
TKRLLDLTLRSRDHILALLDASAGSGEVDRSQGDEIIASLQQLLPQAVGGGGEVEAAPSQSESGEAEATEEKTWRIRFRP
TRELLLFGTNPVSLINELRSLGECHVVAQLDEIPLLDDLTAEHCYLYWDIILTSTRGEDAIKDVFIFVEDDCDIKIQLID
SGGLIDREDGYKKLGHILVERGDLSVEEMQTVLTQQKRFGELLVEQGIVDPEKVQSALIEQQHVKAVRQERSAAPQADAA
ASIRVPAERLDQLINLVGEMVTVQARLSQVSLACGDATFISISEEVERLTNELRDTALNIRMLPIGSTFSKFKRLVRDLS
QELGKEIEMETFGAETELDKTVIEKLNDPLVHIIRNSIDHGIEMPDVRRAAGKPSVGTVCLGAVHSGDSVLITIRDDGAG
LDRDTIRAKAVERGLLAATAEVSDKEIYSQIFAPGFSTAQKITNISGRGVGMDVVKRGIQDLRGTIEVDSVRGSGTTITL
RIPLTLAIIESLLVKIGDSHFVLPLAAVEECVELTREDVEAAHGRNLAIIRGNLTPFISLREQFEIDGDRPDIEQIVIVS
VNGMRIGFVVDFVVGEHQTVIKPLGRLYQDIKGVSGATILGDGSVALILDPGVLTQCAEMAEASLTQ

Sequences:

>Translated_707_residues
MMEQAIATYREEASELLAELESSLLELEDTPDDDDLINRVFRAMHTIKGSGAMFGFDEIASFTHEVETVFDMVRNGKMSV
TKRLLDLTLRSRDHILALLDASAGSGEVDRSQGDEIIASLQQLLPQAVGGGGEVEAAPSQSESGEAEATEEKTWRIRFRP
TRELLLFGTNPVSLINELRSLGECHVVAQLDEIPLLDDLTAEHCYLYWDIILTSTRGEDAIKDVFIFVEDDCDIKIQLID
SGGLIDREDGYKKLGHILVERGDLSVEEMQTVLTQQKRFGELLVEQGIVDPEKVQSALIEQQHVKAVRQERSAAPQADAA
ASIRVPAERLDQLINLVGEMVTVQARLSQVSLACGDATFISISEEVERLTNELRDTALNIRMLPIGSTFSKFKRLVRDLS
QELGKEIEMETFGAETELDKTVIEKLNDPLVHIIRNSIDHGIEMPDVRRAAGKPSVGTVCLGAVHSGDSVLITIRDDGAG
LDRDTIRAKAVERGLLAATAEVSDKEIYSQIFAPGFSTAQKITNISGRGVGMDVVKRGIQDLRGTIEVDSVRGSGTTITL
RIPLTLAIIESLLVKIGDSHFVLPLAAVEECVELTREDVEAAHGRNLAIIRGNLTPFISLREQFEIDGDRPDIEQIVIVS
VNGMRIGFVVDFVVGEHQTVIKPLGRLYQDIKGVSGATILGDGSVALILDPGVLTQCAEMAEASLTQ
>Mature_707_residues
MMEQAIATYREEASELLAELESSLLELEDTPDDDDLINRVFRAMHTIKGSGAMFGFDEIASFTHEVETVFDMVRNGKMSV
TKRLLDLTLRSRDHILALLDASAGSGEVDRSQGDEIIASLQQLLPQAVGGGGEVEAAPSQSESGEAEATEEKTWRIRFRP
TRELLLFGTNPVSLINELRSLGECHVVAQLDEIPLLDDLTAEHCYLYWDIILTSTRGEDAIKDVFIFVEDDCDIKIQLID
SGGLIDREDGYKKLGHILVERGDLSVEEMQTVLTQQKRFGELLVEQGIVDPEKVQSALIEQQHVKAVRQERSAAPQADAA
ASIRVPAERLDQLINLVGEMVTVQARLSQVSLACGDATFISISEEVERLTNELRDTALNIRMLPIGSTFSKFKRLVRDLS
QELGKEIEMETFGAETELDKTVIEKLNDPLVHIIRNSIDHGIEMPDVRRAAGKPSVGTVCLGAVHSGDSVLITIRDDGAG
LDRDTIRAKAVERGLLAATAEVSDKEIYSQIFAPGFSTAQKITNISGRGVGMDVVKRGIQDLRGTIEVDSVRGSGTTITL
RIPLTLAIIESLLVKIGDSHFVLPLAAVEECVELTREDVEAAHGRNLAIIRGNLTPFISLREQFEIDGDRPDIEQIVIVS
VNGMRIGFVVDFVVGEHQTVIKPLGRLYQDIKGVSGATILGDGSVALILDPGVLTQCAEMAEASLTQ

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=698, Percent_Identity=36.8194842406877, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77349; Mature: 77349

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEQAIATYREEASELLAELESSLLELEDTPDDDDLINRVFRAMHTIKGSGAMFGFDEIA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEECHHHHH
SFTHEVETVFDMVRNGKMSVTKRLLDLTLRSRDHILALLDASAGSGEVDRSQGDEIIASL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHH
QQLLPQAVGGGGEVEAAPSQSESGEAEATEEKTWRIRFRPTRELLLFGTNPVSLINELRS
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHH
LGECHVVAQLDEIPLLDDLTAEHCYLYWDIILTSTRGEDAIKDVFIFVEDDCDIKIQLID
CCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEEEECCCCEEEEEEE
SGGLIDREDGYKKLGHILVERGDLSVEEMQTVLTQQKRFGELLVEQGIVDPEKVQSALIE
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QQHVKAVRQERSAAPQADAAASIRVPAERLDQLINLVGEMVTVQARLSQVSLACGDATFI
HHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEE
SISEEVERLTNELRDTALNIRMLPIGSTFSKFKRLVRDLSQELGKEIEMETFGAETELDK
EHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHH
TVIEKLNDPLVHIIRNSIDHGIEMPDVRRAAGKPSVGTVCLGAVHSGDSVLITIRDDGAG
HHHHHCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEEEEECCCEEEEEEECCCCC
LDRDTIRAKAVERGLLAATAEVSDKEIYSQIFAPGFSTAQKITNISGRGVGMDVVKRGIQ
CCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHH
DLRGTIEVDSVRGSGTTITLRIPLTLAIIESLLVKIGDSHFVLPLAAVEECVELTREDVE
HHCCCEEEECCCCCCCEEEEEECHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHH
AAHGRNLAIIRGNLTPFISLREQFEIDGDRPDIEQIVIVSVNGMRIGFVVDFVVGEHQTV
HHCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCEEEEEEEEEHHCCCHHH
IKPLGRLYQDIKGVSGATILGDGSVALILDPGVLTQCAEMAEASLTQ
HHHHHHHHHHHCCCCCCEEEECCCEEEEECCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMEQAIATYREEASELLAELESSLLELEDTPDDDDLINRVFRAMHTIKGSGAMFGFDEIA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEECHHHHH
SFTHEVETVFDMVRNGKMSVTKRLLDLTLRSRDHILALLDASAGSGEVDRSQGDEIIASL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHH
QQLLPQAVGGGGEVEAAPSQSESGEAEATEEKTWRIRFRPTRELLLFGTNPVSLINELRS
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHH
LGECHVVAQLDEIPLLDDLTAEHCYLYWDIILTSTRGEDAIKDVFIFVEDDCDIKIQLID
CCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEEEECCCCEEEEEEE
SGGLIDREDGYKKLGHILVERGDLSVEEMQTVLTQQKRFGELLVEQGIVDPEKVQSALIE
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QQHVKAVRQERSAAPQADAAASIRVPAERLDQLINLVGEMVTVQARLSQVSLACGDATFI
HHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEE
SISEEVERLTNELRDTALNIRMLPIGSTFSKFKRLVRDLSQELGKEIEMETFGAETELDK
EHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHH
TVIEKLNDPLVHIIRNSIDHGIEMPDVRRAAGKPSVGTVCLGAVHSGDSVLITIRDDGAG
HHHHHCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEEEEECCCEEEEEEECCCCC
LDRDTIRAKAVERGLLAATAEVSDKEIYSQIFAPGFSTAQKITNISGRGVGMDVVKRGIQ
CCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHH
DLRGTIEVDSVRGSGTTITLRIPLTLAIIESLLVKIGDSHFVLPLAAVEECVELTREDVE
HHCCCEEEECCCCCCCEEEEEECHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHH
AAHGRNLAIIRGNLTPFISLREQFEIDGDRPDIEQIVIVSVNGMRIGFVVDFVVGEHQTV
HHCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCEEEEEEEEEHHCCCHHH
IKPLGRLYQDIKGVSGATILGDGSVALILDPGVLTQCAEMAEASLTQ
HHHHHHHHHHHCCCCCCEEEECCCEEEEECCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]