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The map label for this gene is aroF [H]

Identifier: 118580008

GI number: 118580008

Start: 1692178

End: 1693197

Strand: Direct

Name: aroF [H]

Synonym: Ppro_1585

Alternate gene names: 118580008

Gene position: 1692178-1693197 (Clockwise)

Preceding gene: 118580007

Following gene: 118580009

Centisome position: 42.22

GC content: 61.76

Gene sequence:

>1020_bases
ATGATCATCGTCATGAAGGCCGGGGCAACCAAGAAGGAACGGGACGAGGTATTGAAGCGCATCAGGGAACTGGGCTACAA
GCCGCATGTCATCCACGGTTCCACCAGGGACGTGATCGGGGCCATCGGAGACGAGCGGGGAAAGGCGGTGTTGCAGAAGG
TGGAATCCATGCACGGAGTCGAGAATGTCCTGCCGATCCTCCAGCCGTACAAGTTGGCTTCCAAGGAGCTGAAGAAAGAG
GCCAGTCTGGTGCGGGTCAACGATCAGGTCTGCATCGGCGGCCAGCAGTTGATCGTCATGGCCGGCCCCTGTTCCGTGGA
GAGCGAGGAGCAGATCATCGAGTCGGCGATAGCGGTGAAGGCGGCCGGGGCGCAGATGCTGCGGGGCGGTGCCTTCAAGC
CGCGCACCTCTCCCTACTCCTTCCAGGGGATGGAGGAAGAGGGGCTAAAACTCTTGGCCAAGGCGCGCGAGGTAACCGGT
CTTCCCTTTGTCACCGAGGTGATCAACCCGGAGACCGCCGAACTGGTTGCCGAATACTCCGACATGCTGCAGATCGGCGC
CCGCAACGCACAGAACTTCGCCCTATTGAAGAAGGTCGGTCAGCTCAAACGTCCTGTGCTGCTGAAACGGGGTATGTCCA
TGACGATCCAGGAGTTCCTGATGAGCGCCGAGTACATCATGAGCGAGGGAAACCAGTCGGTGATCCTCTGCGAGCGGGGT
ATCCGCACCTTCGAGACAGCCACCCGCAACACGCTGGACCTGTCGGCCATACCGGTGCTGAAAGGGAAGACCCATCTGCC
GGTGGTGATCGATCCCTCCCACGGCACCGGCAACCACCACTATGTTGCGCCCATGTGCTACGCCGCCGTGGCGGCAGGAG
CAGACGGGCTGATGGTGGAGGTGCACCCCGACCCGGAAAACGCCTCCAGCGACGGCGCCCAGTCGCTCAAGCCGGTTAAG
TTCGCCGCCATGATGGAAAAGCTGAAGCTGTTCGCCGCGGCGGCAGGGAGGACCCTCTAG

Upstream 100 bases:

>100_bases
TCTCCCCGGCTTTTTTTATGCAGCCGCACCAGGTGCGGGTTCAGGAGCCGGGGGGGAACCTTCCGGCTCCTGTTCGTTTT
GTGGCCAAAAAGGAGCAGAG

Downstream 100 bases:

>100_bases
GTCGGAGTGCCCAGCCAACCTCCCGCCCTCTCCCGGAGCGGGGAAGCTGCGTTATACTGGGAGAACGCCGTTCGATCGGG
GGGCGGCGTTCCCTGTTTCC

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIIVMKAGATKKERDEVLKRIRELGYKPHVIHGSTRDVIGAIGDERGKAVLQKVESMHGVENVLPILQPYKLASKELKKE
ASLVRVNDQVCIGGQQLIVMAGPCSVESEEQIIESAIAVKAAGAQMLRGGAFKPRTSPYSFQGMEEEGLKLLAKAREVTG
LPFVTEVINPETAELVAEYSDMLQIGARNAQNFALLKKVGQLKRPVLLKRGMSMTIQEFLMSAEYIMSEGNQSVILCERG
IRTFETATRNTLDLSAIPVLKGKTHLPVVIDPSHGTGNHHYVAPMCYAAVAAGADGLMVEVHPDPENASSDGAQSLKPVK
FAAMMEKLKLFAAAAGRTL

Sequences:

>Translated_339_residues
MIIVMKAGATKKERDEVLKRIRELGYKPHVIHGSTRDVIGAIGDERGKAVLQKVESMHGVENVLPILQPYKLASKELKKE
ASLVRVNDQVCIGGQQLIVMAGPCSVESEEQIIESAIAVKAAGAQMLRGGAFKPRTSPYSFQGMEEEGLKLLAKAREVTG
LPFVTEVINPETAELVAEYSDMLQIGARNAQNFALLKKVGQLKRPVLLKRGMSMTIQEFLMSAEYIMSEGNQSVILCERG
IRTFETATRNTLDLSAIPVLKGKTHLPVVIDPSHGTGNHHYVAPMCYAAVAAGADGLMVEVHPDPENASSDGAQSLKPVK
FAAMMEKLKLFAAAAGRTL
>Mature_339_residues
MIIVMKAGATKKERDEVLKRIRELGYKPHVIHGSTRDVIGAIGDERGKAVLQKVESMHGVENVLPILQPYKLASKELKKE
ASLVRVNDQVCIGGQQLIVMAGPCSVESEEQIIESAIAVKAAGAQMLRGGAFKPRTSPYSFQGMEEEGLKLLAKAREVTG
LPFVTEVINPETAELVAEYSDMLQIGARNAQNFALLKKVGQLKRPVLLKRGMSMTIQEFLMSAEYIMSEGNQSVILCERG
IRTFETATRNTLDLSAIPVLKGKTHLPVVIDPSHGTGNHHYVAPMCYAAVAAGADGLMVEVHPDPENASSDGAQSLKPVK
FAAMMEKLKLFAAAAGRTL

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=208, Percent_Identity=26.9230769230769, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 36716; Mature: 36716

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVMKAGATKKERDEVLKRIRELGYKPHVIHGSTRDVIGAIGDERGKAVLQKVESMHGV
CEEEEECCCCHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHCCHHHHHHHHHHHHHHCH
ENVLPILQPYKLASKELKKEASLVRVNDQVCIGGQQLIVMAGPCSVESEEQIIESAIAVK
HHHHHHHCCHHHHHHHHHHHHHEEEECCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHH
AAGAQMLRGGAFKPRTSPYSFQGMEEEGLKLLAKAREVTGLPFVTEVINPETAELVAEYS
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHH
DMLQIGARNAQNFALLKKVGQLKRPVLLKRGMSMTIQEFLMSAEYIMSEGNQSVILCERG
HHHHHCCCCCHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
IRTFETATRNTLDLSAIPVLKGKTHLPVVIDPSHGTGNHHYVAPMCYAAVAAGADGLMVE
CHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEE
VHPDPENASSDGAQSLKPVKFAAMMEKLKLFAAAAGRTL
ECCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIIVMKAGATKKERDEVLKRIRELGYKPHVIHGSTRDVIGAIGDERGKAVLQKVESMHGV
CEEEEECCCCHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHCCHHHHHHHHHHHHHHCH
ENVLPILQPYKLASKELKKEASLVRVNDQVCIGGQQLIVMAGPCSVESEEQIIESAIAVK
HHHHHHHCCHHHHHHHHHHHHHEEEECCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHH
AAGAQMLRGGAFKPRTSPYSFQGMEEEGLKLLAKAREVTGLPFVTEVINPETAELVAEYS
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHH
DMLQIGARNAQNFALLKKVGQLKRPVLLKRGMSMTIQEFLMSAEYIMSEGNQSVILCERG
HHHHHCCCCCHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
IRTFETATRNTLDLSAIPVLKGKTHLPVVIDPSHGTGNHHYVAPMCYAAVAAGADGLMVE
CHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEE
VHPDPENASSDGAQSLKPVKFAAMMEKLKLFAAAAGRTL
ECCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]