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The map label for this gene is ispH

Identifier: 118579777

GI number: 118579777

Start: 1430899

End: 1431741

Strand: Direct

Name: ispH

Synonym: Ppro_1349

Alternate gene names: 118579777

Gene position: 1430899-1431741 (Clockwise)

Preceding gene: 118579776

Following gene: 118579778

Centisome position: 35.7

GC content: 60.02

Gene sequence:

>843_bases
ATGAGAGTAATCCTTGCCAAGCGAGCCGGTTTCTGCTTCGGCGTCAAGCGCGCCACACAGATGGCCTTCGAGGCGGCCGG
GATGGACAAGAAAACCTATACTCTGGGTCCGATCATTCATTCGCCCCAGGTGGTCAAGAAGCTGGAAGAGATGGGGGTGC
GGGCGCTGAAGGACCTGGACAGCATGGACAGCGGCACGATCATCATCCGCTCCCACGGCGTTGCGTCCCACGAAATCGCC
GAAGCCATGCAAAAGAAGCTGGAGATCGTGGATGCCACCTGCCCCTTCGTGAAAAAGGCCCAGGAGCACGTCAAGAGTCT
GTCGGAAACCGGCTACGGTGTGGTAGTGGTGGGCGATGCCGACCACCCCGAGGTGCAGGGTATCGTCTCCTACGGTGGTG
ACAAGGTCTTTGTGGTCGGATCGGGCGAAGAGGTCAGGAAGCTACCGATCATGAACAAGATCGGCGTGGTCGCCCAGACG
ACCCAGTCATTCGAGAATCTGAAGAACGTGGTTTCGGAGTGTCTCCAGCGGGGGGGCGAAATCCGCGTATTCAACACCAT
CTGCGACGCAACGGCTGTTCGCCAGGAGGAGGCCAAGGAACTGGCCCGCCAGGTTGACTGCATGCTGGTGGTGGGCGGTT
TCAACAGCGCCAACACGCGCCGCCTGGCCGAAGTCTGCGCGGAACTGCAGCCGCGGACTCACCACATCGAGACCGCAGCC
GAGATTGACCCCGCCTGGTTCGAGGGGGTTGCCACGGTGGGAGTCACTGCCGGCGCGTCGACCCCCAAATGGATTATCGA
TGAGGTGATGGGCAGGATCGGGGAAATCAATAAAAAGAATTGA

Upstream 100 bases:

>100_bases
ATGCCATCGACGTTGATTCCTCGGACATGGGTATCGATGAGGTGGTGGCCTGCATGGAGGCCTTTGTCCGGCAAAAATAC
GTCTGTGGGGAGTCAGTGGA

Downstream 100 bases:

>100_bases
TAATTTATATATCTGTGGTAGATTGTCTGCTTGTTTTGTAACGAACACGCAAAGCATGAAAAAAGAAAACGTTCAGGGGG
TATGGTTTAATGGTTGACTT

Product: hydroxymethylbutenyl pyrophosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MRVILAKRAGFCFGVKRATQMAFEAAGMDKKTYTLGPIIHSPQVVKKLEEMGVRALKDLDSMDSGTIIIRSHGVASHEIA
EAMQKKLEIVDATCPFVKKAQEHVKSLSETGYGVVVVGDADHPEVQGIVSYGGDKVFVVGSGEEVRKLPIMNKIGVVAQT
TQSFENLKNVVSECLQRGGEIRVFNTICDATAVRQEEAKELARQVDCMLVVGGFNSANTRRLAEVCAELQPRTHHIETAA
EIDPAWFEGVATVGVTAGASTPKWIIDEVMGRIGEINKKN

Sequences:

>Translated_280_residues
MRVILAKRAGFCFGVKRATQMAFEAAGMDKKTYTLGPIIHSPQVVKKLEEMGVRALKDLDSMDSGTIIIRSHGVASHEIA
EAMQKKLEIVDATCPFVKKAQEHVKSLSETGYGVVVVGDADHPEVQGIVSYGGDKVFVVGSGEEVRKLPIMNKIGVVAQT
TQSFENLKNVVSECLQRGGEIRVFNTICDATAVRQEEAKELARQVDCMLVVGGFNSANTRRLAEVCAELQPRTHHIETAA
EIDPAWFEGVATVGVTAGASTPKWIIDEVMGRIGEINKKN
>Mature_280_residues
MRVILAKRAGFCFGVKRATQMAFEAAGMDKKTYTLGPIIHSPQVVKKLEEMGVRALKDLDSMDSGTIIIRSHGVASHEIA
EAMQKKLEIVDATCPFVKKAQEHVKSLSETGYGVVVVGDADHPEVQGIVSYGGDKVFVVGSGEEVRKLPIMNKIGVVAQT
TQSFENLKNVVSECLQRGGEIRVFNTICDATAVRQEEAKELARQVDCMLVVGGFNSANTRRLAEVCAELQPRTHHIETAA
EIDPAWFEGVATVGVTAGASTPKWIIDEVMGRIGEINKKN

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family

Homologues:

Organism=Escherichia coli, GI1786212, Length=285, Percent_Identity=34.0350877192982, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ISPH_PELPD (A1ANP9)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901027.1
- STRING:   A1ANP9
- GeneID:   4573836
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1349
- eggNOG:   COG0761
- HOGENOM:   HBG335228
- OMA:   MDVPGFY
- ProtClustDB:   CLSK790176
- HAMAP:   MF_00191
- InterPro:   IPR003451
- TIGRFAMs:   TIGR00216

Pfam domain/function: PF02401 LYTB

EC number: =1.17.1.2

Molecular weight: Translated: 30394; Mature: 30394

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVILAKRAGFCFGVKRATQMAFEAAGMDKKTYTLGPIIHSPQVVKKLEEMGVRALKDLD
CEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHC
SMDSGTIIIRSHGVASHEIAEAMQKKLEIVDATCPFVKKAQEHVKSLSETGYGVVVVGDA
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCC
DHPEVQGIVSYGGDKVFVVGSGEEVRKLPIMNKIGVVAQTTQSFENLKNVVSECLQRGGE
CCCHHHHHEECCCCEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IRVFNTICDATAVRQEEAKELARQVDCMLVVGGFNSANTRRLAEVCAELQPRTHHIETAA
EEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHH
EIDPAWFEGVATVGVTAGASTPKWIIDEVMGRIGEINKKN
HCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRVILAKRAGFCFGVKRATQMAFEAAGMDKKTYTLGPIIHSPQVVKKLEEMGVRALKDLD
CEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHC
SMDSGTIIIRSHGVASHEIAEAMQKKLEIVDATCPFVKKAQEHVKSLSETGYGVVVVGDA
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCC
DHPEVQGIVSYGGDKVFVVGSGEEVRKLPIMNKIGVVAQTTQSFENLKNVVSECLQRGGE
CCCHHHHHEECCCCEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IRVFNTICDATAVRQEEAKELARQVDCMLVVGGFNSANTRRLAEVCAELQPRTHHIETAA
EEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHH
EIDPAWFEGVATVGVTAGASTPKWIIDEVMGRIGEINKKN
HCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA