| Definition | Pelobacter propionicus DSM 2379 chromosome, complete genome. |
|---|---|
| Accession | NC_008609 |
| Length | 4,008,000 |
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The map label for this gene is slt [H]
Identifier: 118579739
GI number: 118579739
Start: 1383151
End: 1385316
Strand: Direct
Name: slt [H]
Synonym: Ppro_1311
Alternate gene names: 118579739
Gene position: 1383151-1385316 (Clockwise)
Preceding gene: 118579738
Following gene: 118579741
Centisome position: 34.51
GC content: 56.33
Gene sequence:
>2166_bases ATGGTGTGTCATCTGATTAACGCAATTCCAAGGCCATGGGCGTCCATCCAGGGCCTTGTTCACGAAAGGCAGATCATGTT TCGAACCACCCGAAGACCTTTTGTTATCGCATTGGCAGGTATTTCGCTCGTTTCCCTTGTCAGTCTCTCCTGTCATGCCG ATGACGCGCTCACCAGTGCCGTATCGCAGTTTCGGGAGAAGGACCATACGGACGGTTTTGCTTTGGCACTGAAAACTGCC GATTCTCCGCAGCGTACGTTTTTGCTGGGGGTCAGCGCCCTCCGTCAAGGGAAGACCGAAGAATCCCTGTCCCTGTTGGG GGAGGCTGAGCAGAAATTGCCACTGCTGGGAGATTATGCCGCCTACTATCAGGCCGAGGCATTGTTTAAGCTGAAAAGGT ATCCCGAGGCGGCTGCCAAGGCGGTTGCCATACCCAAGGAGTACCCGGTTTCTTTGCTGGTCCGACGTTCGTTGAAGCTT CAACTCGACAGCGTTGTGGCTGCTGGAGATTTCGCCGCAGCGCTCAAGCTGTCCCAGGCTTTTGTCGAGAAATACCCCTC TGGCGCGGATTCCGTGGACGCGCTTTTCCTGTCCGGCCTCTGCCGCGAGGAGCTGGGCAATACGAACGGCGCGGTCCAGA TTTACCGGAGCATCTGGCTGAATACCCCGCTTGCCTTACAGGCTGTGAAATCCCAGGACCGCCTCAAGGAACTGGAGAAG CGGGGCATCGCCAGCAACTCTTTTACGGCTGAGGAACTGCTTCGCCGAGCCTCCGCGTTTTCCGCGAAAAACTCCTTTTC GCACTCACTGCGGACACTCCAGGCAATTCCGCTGGAAGGACAGTCAGCGGCCCTGGTCGATCTCGTTATGTTGCGTACCG GCCTGAACCAGTATCGCATGCGCAACTGGAAGGAGGCCGAAAAGAGTCTGGTCAGGGCAGGAACCAGCAACAATGTCTCC ATACGATCCGAAGCTCGCTTTTGGCAGGCCAAAGCCTTGGAACATCTTGACCAGGGTGGACGGGCTTTTACCATGTTAAT GGAATTGGCTGGCGAGGGGCAGAAACAGGAATTCGCCGATGATGCCCTGATGGAGGCCGCCGACCTGCGAAAGGGGGCAG GGAGCTATGCCGAGGCTGCTCTTCTGTTTGAAAGAGTTGCTCTACTCTGCCCGGAATCAAAGCATGTCAGTCGGGCTGCC TGGGAGTCGGGCTGGTGTCATTACCTTGCGGGAGAACATGCTGCGGCTGCCGTGTCATTCAAGGCGCTTTTGAATGAGGG CGGCCAGCGGGAAAAGGCTCTCTACTGGCTGGGACGTGTGCTGGAGAACAGCGGCAATGCAGAGTCGGCAGACTGTTACA GCACGCTTTTGAACGAATATCCGGCAGGTTTTTACGCCGCGTGGCACCGGGAGAAGAAGGGGATCCAGGACAACCGTGAA TCCCTTGCCCAACGTTCCACCATGATTGCTTCACCGCTTCCGTCCGGTTATGAAAAACCGCTTCTGTTGGCTTCACTGGG CATGATTGACGAGGCCCGTCGGGAGGCGGCTGTTCGACGGAAGAATGGTGACAAAAAGGGGCAGTATCCCGGCTTTGCGC GACTCTATCTGGAAATGGGCGATTATGGATCAGCCATTTACCTCTTTCAGCAGAACCGCTCACTAAAGTGGGAAAAAGAA AGCTTGCCACTCTGGACCGCAGGTTATCCCCTGGCCTATACGGGTCAGGTGGCGCAGCAGACAGCTGCCAACAGCCTCTC CGAGGCGCTGATTTATGCCCTGATTCGTGCCGAGAGCAGTTTCTCGCCTACAGTGAAATCTCCGGCAGGGGCCATCGGCC TGATGCAGCTCATGCCGGCAACGGCCAAGGCAACTGCCCGCGAAAAGGGCACCTTTGATCCCGCTCGACTGACAACCCCC GATTACAACATCATGTTGGGGACGCGGCATTTTCGCGATCTTTTGAATGGGTATGACGGCGATGTGGTTTTTTCGGTCGC CGCCTACAATGCCGGTGCAGGTGCGGTGGCGCGCTGGAGAAAGAGGCTTAAAGGGCTTGATAAGGATGAATTCATTGAAA GCATACCCTATAAGGAGACTCGTGACTACGTCAAAAAGGTCTATGCTGCGGCCGCCACCTACCGGCAGTTGTATGGGTTG CGCTGA
Upstream 100 bases:
>100_bases TGTCTGTGCTGTTACGATCAAGGCGGGCCCCGTACGCTTCCACTGCTTCATGTCTGAAAGGGCGACTGCTGCGGAATGCA GCCTAGGGTTTGCATGAGTT
Downstream 100 bases:
>100_bases CATGCCGGTTCCTTCCTCTGATACCGGAGGTTGTTGTCGGCGACGTCCGGCGAATAACGGTTACGGTGGAATCGCCCCGC CCGAACTGTAACGTGGGGAC
Product: lytic transglycosylase catalytic subunit
Products: 1,6-Anhydrobond [C]
Alternate protein names: Exomuramidase; Peptidoglycan lytic exotransglycosylase; Slt70 [H]
Number of amino acids: Translated: 721; Mature: 721
Protein sequence:
>721_residues MVCHLINAIPRPWASIQGLVHERQIMFRTTRRPFVIALAGISLVSLVSLSCHADDALTSAVSQFREKDHTDGFALALKTA DSPQRTFLLGVSALRQGKTEESLSLLGEAEQKLPLLGDYAAYYQAEALFKLKRYPEAAAKAVAIPKEYPVSLLVRRSLKL QLDSVVAAGDFAAALKLSQAFVEKYPSGADSVDALFLSGLCREELGNTNGAVQIYRSIWLNTPLALQAVKSQDRLKELEK RGIASNSFTAEELLRRASAFSAKNSFSHSLRTLQAIPLEGQSAALVDLVMLRTGLNQYRMRNWKEAEKSLVRAGTSNNVS IRSEARFWQAKALEHLDQGGRAFTMLMELAGEGQKQEFADDALMEAADLRKGAGSYAEAALLFERVALLCPESKHVSRAA WESGWCHYLAGEHAAAAVSFKALLNEGGQREKALYWLGRVLENSGNAESADCYSTLLNEYPAGFYAAWHREKKGIQDNRE SLAQRSTMIASPLPSGYEKPLLLASLGMIDEARREAAVRRKNGDKKGQYPGFARLYLEMGDYGSAIYLFQQNRSLKWEKE SLPLWTAGYPLAYTGQVAQQTAANSLSEALIYALIRAESSFSPTVKSPAGAIGLMQLMPATAKATAREKGTFDPARLTTP DYNIMLGTRHFRDLLNGYDGDVVFSVAAYNAGAGAVARWRKRLKGLDKDEFIESIPYKETRDYVKKVYAAAATYRQLYGL R
Sequences:
>Translated_721_residues MVCHLINAIPRPWASIQGLVHERQIMFRTTRRPFVIALAGISLVSLVSLSCHADDALTSAVSQFREKDHTDGFALALKTA DSPQRTFLLGVSALRQGKTEESLSLLGEAEQKLPLLGDYAAYYQAEALFKLKRYPEAAAKAVAIPKEYPVSLLVRRSLKL QLDSVVAAGDFAAALKLSQAFVEKYPSGADSVDALFLSGLCREELGNTNGAVQIYRSIWLNTPLALQAVKSQDRLKELEK RGIASNSFTAEELLRRASAFSAKNSFSHSLRTLQAIPLEGQSAALVDLVMLRTGLNQYRMRNWKEAEKSLVRAGTSNNVS IRSEARFWQAKALEHLDQGGRAFTMLMELAGEGQKQEFADDALMEAADLRKGAGSYAEAALLFERVALLCPESKHVSRAA WESGWCHYLAGEHAAAAVSFKALLNEGGQREKALYWLGRVLENSGNAESADCYSTLLNEYPAGFYAAWHREKKGIQDNRE SLAQRSTMIASPLPSGYEKPLLLASLGMIDEARREAAVRRKNGDKKGQYPGFARLYLEMGDYGSAIYLFQQNRSLKWEKE SLPLWTAGYPLAYTGQVAQQTAANSLSEALIYALIRAESSFSPTVKSPAGAIGLMQLMPATAKATAREKGTFDPARLTTP DYNIMLGTRHFRDLLNGYDGDVVFSVAAYNAGAGAVARWRKRLKGLDKDEFIESIPYKETRDYVKKVYAAAATYRQLYGL R >Mature_721_residues MVCHLINAIPRPWASIQGLVHERQIMFRTTRRPFVIALAGISLVSLVSLSCHADDALTSAVSQFREKDHTDGFALALKTA DSPQRTFLLGVSALRQGKTEESLSLLGEAEQKLPLLGDYAAYYQAEALFKLKRYPEAAAKAVAIPKEYPVSLLVRRSLKL QLDSVVAAGDFAAALKLSQAFVEKYPSGADSVDALFLSGLCREELGNTNGAVQIYRSIWLNTPLALQAVKSQDRLKELEK RGIASNSFTAEELLRRASAFSAKNSFSHSLRTLQAIPLEGQSAALVDLVMLRTGLNQYRMRNWKEAEKSLVRAGTSNNVS IRSEARFWQAKALEHLDQGGRAFTMLMELAGEGQKQEFADDALMEAADLRKGAGSYAEAALLFERVALLCPESKHVSRAA WESGWCHYLAGEHAAAAVSFKALLNEGGQREKALYWLGRVLENSGNAESADCYSTLLNEYPAGFYAAWHREKKGIQDNRE SLAQRSTMIASPLPSGYEKPLLLASLGMIDEARREAAVRRKNGDKKGQYPGFARLYLEMGDYGSAIYLFQQNRSLKWEKE SLPLWTAGYPLAYTGQVAQQTAANSLSEALIYALIRAESSFSPTVKSPAGAIGLMQLMPATAKATAREKGTFDPARLTTP DYNIMLGTRHFRDLLNGYDGDVVFSVAAYNAGAGAVARWRKRLKGLDKDEFIESIPYKETRDYVKKVYAAAATYRQLYGL R
Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]
COG id: COG0741
COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
Gene ontology:
Cell location: Periplasm. Note=Tightly associated with the murein sacculus (By similarity) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transglycosylase slt family [H]
Homologues:
Organism=Escherichia coli, GI87082441, Length=155, Percent_Identity=40.6451612903226, Blast_Score=114, Evalue=2e-26,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016026 - InterPro: IPR008258 - InterPro: IPR012289 - InterPro: IPR008939 - InterPro: IPR000189 [H]
Pfam domain/function: PF01464 SLT [H]
EC number: 3.2.1.- [C]
Molecular weight: Translated: 79512; Mature: 79512
Theoretical pI: Translated: 9.35; Mature: 9.35
Prosite motif: PS00922 TRANSGLYCOSYLASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVCHLINAIPRPWASIQGLVHERQIMFRTTRRPFVIALAGISLVSLVSLSCHADDALTSA CCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHH VSQFREKDHTDGFALALKTADSPQRTFLLGVSALRQGKTEESLSLLGEAEQKLPLLGDYA HHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHH AYYQAEALFKLKRYPEAAAKAVAIPKEYPVSLLVRRSLKLQLDSVVAAGDFAAALKLSQA HHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH FVEKYPSGADSVDALFLSGLCREELGNTNGAVQIYRSIWLNTPLALQAVKSQDRLKELEK HHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH RGIASNSFTAEELLRRASAFSAKNSFSHSLRTLQAIPLEGQSAALVDLVMLRTGLNQYRM CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHH RNWKEAEKSLVRAGTSNNVSIRSEARFWQAKALEHLDQGGRAFTMLMELAGEGQKQEFAD CCHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHH DALMEAADLRKGAGSYAEAALLFERVALLCPESKHVSRAAWESGWCHYLAGEHAAAAVSF HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCHHHHHHHH KALLNEGGQREKALYWLGRVLENSGNAESADCYSTLLNEYPAGFYAAWHREKKGIQDNRE HHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHH SLAQRSTMIASPLPSGYEKPLLLASLGMIDEARREAAVRRKNGDKKGQYPGFARLYLEMG HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEC DYGSAIYLFQQNRSLKWEKESLPLWTAGYPLAYTGQVAQQTAANSLSEALIYALIRAESS CCCCEEEEEECCCCCCEECCCCCEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCC FSPTVKSPAGAIGLMQLMPATAKATAREKGTFDPARLTTPDYNIMLGTRHFRDLLNGYDG CCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCEECCCCCEEEECCHHHHHHHCCCCC DVVFSVAAYNAGAGAVARWRKRLKGLDKDEFIESIPYKETRDYVKKVYAAAATYRQLYGL CEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC R C >Mature Secondary Structure MVCHLINAIPRPWASIQGLVHERQIMFRTTRRPFVIALAGISLVSLVSLSCHADDALTSA CCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHH VSQFREKDHTDGFALALKTADSPQRTFLLGVSALRQGKTEESLSLLGEAEQKLPLLGDYA HHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHH AYYQAEALFKLKRYPEAAAKAVAIPKEYPVSLLVRRSLKLQLDSVVAAGDFAAALKLSQA HHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH FVEKYPSGADSVDALFLSGLCREELGNTNGAVQIYRSIWLNTPLALQAVKSQDRLKELEK HHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH RGIASNSFTAEELLRRASAFSAKNSFSHSLRTLQAIPLEGQSAALVDLVMLRTGLNQYRM CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHH RNWKEAEKSLVRAGTSNNVSIRSEARFWQAKALEHLDQGGRAFTMLMELAGEGQKQEFAD CCHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHH DALMEAADLRKGAGSYAEAALLFERVALLCPESKHVSRAAWESGWCHYLAGEHAAAAVSF HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCHHHHHHHH KALLNEGGQREKALYWLGRVLENSGNAESADCYSTLLNEYPAGFYAAWHREKKGIQDNRE HHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHH SLAQRSTMIASPLPSGYEKPLLLASLGMIDEARREAAVRRKNGDKKGQYPGFARLYLEMG HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEC DYGSAIYLFQQNRSLKWEKESLPLWTAGYPLAYTGQVAQQTAANSLSEALIYALIRAESS CCCCEEEEEECCCCCCEECCCCCEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCC FSPTVKSPAGAIGLMQLMPATAKATAREKGTFDPARLTTPDYNIMLGTRHFRDLLNGYDG CCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCEECCCCCEEEECCHHHHHHHCCCCC DVVFSVAAYNAGAGAVARWRKRLKGLDKDEFIESIPYKETRDYVKKVYAAAATYRQLYGL CEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC R C
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]
Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]
General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]