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The map label for this gene is trpB [H]

Identifier: 118579719

GI number: 118579719

Start: 1360301

End: 1361494

Strand: Reverse

Name: trpB [H]

Synonym: Ppro_1291

Alternate gene names: 118579719

Gene position: 1361494-1360301 (Counterclockwise)

Preceding gene: 118579720

Following gene: 118579718

Centisome position: 33.97

GC content: 62.14

Gene sequence:

>1194_bases
GTGAATCTACCCGATAAAAAAGGCCATTTCGGTGAATTTGGCGGACGGTACGTTCCGGAGACACTCATGCCGGCCCTGCT
GGAACTGGAACAGGCCTACAAGCACTACCGCCGCGACCGGGAGTTTCGGGAGGAGTTTGAATACTACCTGCGTCAGTACG
TCGGTCGCCCGAACCCGCTCTATTTCGCGGAGAAGTTGACCGAGAAGCTGGGCGGTGCCAGGATCTACCTGAAGCGCGAG
GACCTGAACCACACCGGTGCCCACAAGGTGAACAACACCATCGGACAGGCACTGCTGGCAAAGCGCATGGGGAAACAGCG
GGTCATCGCCGAAACGGGCGCAGGCCAGCACGGCGTGGCCACCGCCACGGTTGCCGCACTGTTCGGCATGCAGTGCGAAG
TCTTCATGGGGGAGGAGGACACTCGCCGCCAGGCCCTGAACGTTTTCCGCATGAAGCTCCTGGGAGCCACGGTCACGCCA
GTCACAGCCGGCACAGCCACCCTGAAGGACGCCATGAATGAGGCCATGCGAAACTGGGTCACCACCATCAAGGATACCTT
CTACGTTATCGGCACCGTGGCCGGCCCACATCCCTACCCCATGATCGTGCGCGACTTCCAGTCCGTGATCGGCAAAGAGG
TCAAACAACAGCACCGCAGGGTGGAGGGAAAGCTTCCCGACTGCCTGGTGGCCTGTGTGGGGGGGGGGAGTAACGCCATG
GGGCTGTTCTACCCCTTTCTGAAAGACAAGGATGTTCGCCTGGTGGGCGTCGAGGCGGCCGGTTACGGCATCGACAGCGG
CCAACACGCAGCCACGCTCTGCGCCGGATCACCCGGCATCCTGCACGGCAACAAGACCTACCTGCTGCAGGATGAGCATG
GCCAGATCAGCCCTGCCCACTCCATCTCCGCCGGCCTCGATTACCCCGGCGTGGGACCGGAGCACTCCTGGCTGAAGGAC
TGCGGCCGGGCCGAATACGCCTCCGTCACCGACGAAGAGGCGCTGGAGGGCTTTCGGCTTCTGACCCGCGAAGAAGGGAT
CATGCCAGCCCTGGAATCGTCCCACGCCATCGCGCACCTGGTTAAGCTTGCCCCTACCATGCCAAAGGATGCCAGCATAG
TGGTCTGCCTCTCTGGCCGCGGAGACAAGGACATCCACACCGTTGCCGAAGCAATGGGGATCAGCTTTGCCTGA

Upstream 100 bases:

>100_bases
CCCTACGGCGTGGACGTGTCCAGCGGAGTCGAAGCCGCTCCGGGCAAAAAGGATGCTGTAAAGATCAGAGAGTTTATCAG
AATAGCGAAGGAGACCCGCA

Downstream 100 bases:

>100_bases
GAGGGCATGACCGCAAGGACCCGCCTTAAGCGGGGACAGACTGTTTTTAATATTGGTTATTTCAATCCGGCGATGTACAA
TCGCTCATTTTTATGCTGTT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNLPDKKGHFGEFGGRYVPETLMPALLELEQAYKHYRRDREFREEFEYYLRQYVGRPNPLYFAEKLTEKLGGARIYLKRE
DLNHTGAHKVNNTIGQALLAKRMGKQRVIAETGAGQHGVATATVAALFGMQCEVFMGEEDTRRQALNVFRMKLLGATVTP
VTAGTATLKDAMNEAMRNWVTTIKDTFYVIGTVAGPHPYPMIVRDFQSVIGKEVKQQHRRVEGKLPDCLVACVGGGSNAM
GLFYPFLKDKDVRLVGVEAAGYGIDSGQHAATLCAGSPGILHGNKTYLLQDEHGQISPAHSISAGLDYPGVGPEHSWLKD
CGRAEYASVTDEEALEGFRLLTREEGIMPALESSHAIAHLVKLAPTMPKDASIVVCLSGRGDKDIHTVAEAMGISFA

Sequences:

>Translated_397_residues
MNLPDKKGHFGEFGGRYVPETLMPALLELEQAYKHYRRDREFREEFEYYLRQYVGRPNPLYFAEKLTEKLGGARIYLKRE
DLNHTGAHKVNNTIGQALLAKRMGKQRVIAETGAGQHGVATATVAALFGMQCEVFMGEEDTRRQALNVFRMKLLGATVTP
VTAGTATLKDAMNEAMRNWVTTIKDTFYVIGTVAGPHPYPMIVRDFQSVIGKEVKQQHRRVEGKLPDCLVACVGGGSNAM
GLFYPFLKDKDVRLVGVEAAGYGIDSGQHAATLCAGSPGILHGNKTYLLQDEHGQISPAHSISAGLDYPGVGPEHSWLKD
CGRAEYASVTDEEALEGFRLLTREEGIMPALESSHAIAHLVKLAPTMPKDASIVVCLSGRGDKDIHTVAEAMGISFA
>Mature_397_residues
MNLPDKKGHFGEFGGRYVPETLMPALLELEQAYKHYRRDREFREEFEYYLRQYVGRPNPLYFAEKLTEKLGGARIYLKRE
DLNHTGAHKVNNTIGQALLAKRMGKQRVIAETGAGQHGVATATVAALFGMQCEVFMGEEDTRRQALNVFRMKLLGATVTP
VTAGTATLKDAMNEAMRNWVTTIKDTFYVIGTVAGPHPYPMIVRDFQSVIGKEVKQQHRRVEGKLPDCLVACVGGGSNAM
GLFYPFLKDKDVRLVGVEAAGYGIDSGQHAATLCAGSPGILHGNKTYLLQDEHGQISPAHSISAGLDYPGVGPEHSWLKD
CGRAEYASVTDEEALEGFRLLTREEGIMPALESSHAIAHLVKLAPTMPKDASIVVCLSGRGDKDIHTVAEAMGISFA

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=385, Percent_Identity=54.8051948051948, Blast_Score=436, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=59.8958333333333, Blast_Score=477, Evalue=1e-135,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43507; Mature: 43507

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPDKKGHFGEFGGRYVPETLMPALLELEQAYKHYRRDREFREEFEYYLRQYVGRPNPL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
YFAEKLTEKLGGARIYLKREDLNHTGAHKVNNTIGQALLAKRMGKQRVIAETGAGQHGVA
HHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHEEHHCCCCCCCHH
TATVAALFGMQCEVFMGEEDTRRQALNVFRMKLLGATVTPVTAGTATLKDAMNEAMRNWV
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
TTIKDTFYVIGTVAGPHPYPMIVRDFQSVIGKEVKQQHRRVEGKLPDCLVACVGGGSNAM
HHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
GLFYPFLKDKDVRLVGVEAAGYGIDSGQHAATLCAGSPGILHGNKTYLLQDEHGQISPAH
HHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEECCCCCEEECCEEEEEECCCCCCCCCH
SISAGLDYPGVGPEHSWLKDCGRAEYASVTDEEALEGFRLLTREEGIMPALESSHAIAHL
HHHCCCCCCCCCCCHHHHHHCCCCHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VKLAPTMPKDASIVVCLSGRGDKDIHTVAEAMGISFA
HHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNLPDKKGHFGEFGGRYVPETLMPALLELEQAYKHYRRDREFREEFEYYLRQYVGRPNPL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
YFAEKLTEKLGGARIYLKREDLNHTGAHKVNNTIGQALLAKRMGKQRVIAETGAGQHGVA
HHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHEEHHCCCCCCCHH
TATVAALFGMQCEVFMGEEDTRRQALNVFRMKLLGATVTPVTAGTATLKDAMNEAMRNWV
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
TTIKDTFYVIGTVAGPHPYPMIVRDFQSVIGKEVKQQHRRVEGKLPDCLVACVGGGSNAM
HHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
GLFYPFLKDKDVRLVGVEAAGYGIDSGQHAATLCAGSPGILHGNKTYLLQDEHGQISPAH
HHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEECCCCCEEECCEEEEEECCCCCCCCCH
SISAGLDYPGVGPEHSWLKDCGRAEYASVTDEEALEGFRLLTREEGIMPALESSHAIAHL
HHHCCCCCCCCCCCHHHHHHCCCCHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VKLAPTMPKDASIVVCLSGRGDKDIHTVAEAMGISFA
HHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA