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The map label for this gene is hgdC [H]

Identifier: 118579706

GI number: 118579706

Start: 1339077

End: 1339856

Strand: Reverse

Name: hgdC [H]

Synonym: Ppro_1277

Alternate gene names: 118579706

Gene position: 1339856-1339077 (Counterclockwise)

Preceding gene: 118579707

Following gene: 118579672

Centisome position: 33.43

GC content: 66.67

Gene sequence:

>780_bases
ATGATTACCATGGGGTTTGATCTGGGGTCCGCCGCCATCAAGGCGGTCATGGCTGAAGAGGGCCAGGCGGTCTGGTACGG
CACGATGCCGGCCACGGCGCACTACGTCCACTCCTGCGAACTGCTCTTCCGGAAGGGGCTAGGGGAACGGGGAGTGGCGG
AGGAGGATCTGGCCGGCATCGCCGCCACCGGCTACGGCAAGGGGTTGTTCTCACGGGCGGACAAGGTGGTCAACGAGATA
TCGGCCAATGCCCTGGGGGCCTTCTCCCTGAGCGACGGCCAGCTCAGGAGCATCATCAACATCGGCGGCCAGGATGTGAA
GATCATCAAGCTCTGGCCGGACGGGAGCGTGGCTGATTTCAGGATGAACGACAAATGCGCCGCCGGCACCGGCAGGTTCT
TCGAGATGGCGGAACGGATCCTGGACGCGCCGCTGGCGGATTTCGGCAGCATGGACAGGGAGAGCAGTTCCCCGGCGGAG
ATCGGCAGCACCTGCGCCGTGTTCGCCGAGACCGAGCTGATCTCCCTCATGGCCCGGGGGGTGGATCGGAACGACATCGT
CGCCGGCCTGAACCGGGCCATCGCCGCGCGGATTTCCTCCCTGGCCGAGAACATGGATCTTGCCGACGGCATCTGCCTGG
ACGGGGGTCCGGCCCTGAACAGCGGGCTGCACCGGGCAATGGGTGAGGAGATGGGACGGGAGGTGCGGGTCCTGGAGCAG
CCGCAGTTCACCGTGGCCCTGGGGGCGGCGCTGGCAATCGCCCGGGAGAGGGGGCGCTGA

Upstream 100 bases:

>100_bases
CTTTATCCGCATCGAAACCGACCTGTCCCGGGAGGACGGCAAGAACCTGTTGGTGCGCCTGGAGGCGTTCCGCGACCTGC
TGCATGAAAGGAGTTGAATC

Downstream 100 bases:

>100_bases
GTCCGTCGAGGCTCCAGAAGCGCCTCGACGACATGTCCCGCACGATAAAGCTAGACAAAGGTCTGGGGTTCTTTTCTCTC
AGCGCATTTTTCGTTGAGCC

Product: putative CoA-substrate-specific enzyme activase

Products: NA

Alternate protein names: 2-hydroxyglutaryl-CoA dehydratase component A [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MITMGFDLGSAAIKAVMAEEGQAVWYGTMPATAHYVHSCELLFRKGLGERGVAEEDLAGIAATGYGKGLFSRADKVVNEI
SANALGAFSLSDGQLRSIINIGGQDVKIIKLWPDGSVADFRMNDKCAAGTGRFFEMAERILDAPLADFGSMDRESSSPAE
IGSTCAVFAETELISLMARGVDRNDIVAGLNRAIAARISSLAENMDLADGICLDGGPALNSGLHRAMGEEMGREVRVLEQ
PQFTVALGAALAIARERGR

Sequences:

>Translated_259_residues
MITMGFDLGSAAIKAVMAEEGQAVWYGTMPATAHYVHSCELLFRKGLGERGVAEEDLAGIAATGYGKGLFSRADKVVNEI
SANALGAFSLSDGQLRSIINIGGQDVKIIKLWPDGSVADFRMNDKCAAGTGRFFEMAERILDAPLADFGSMDRESSSPAE
IGSTCAVFAETELISLMARGVDRNDIVAGLNRAIAARISSLAENMDLADGICLDGGPALNSGLHRAMGEEMGREVRVLEQ
PQFTVALGAALAIARERGR
>Mature_259_residues
MITMGFDLGSAAIKAVMAEEGQAVWYGTMPATAHYVHSCELLFRKGLGERGVAEEDLAGIAATGYGKGLFSRADKVVNEI
SANALGAFSLSDGQLRSIINIGGQDVKIIKLWPDGSVADFRMNDKCAAGTGRFFEMAERILDAPLADFGSMDRESSSPAE
IGSTCAVFAETELISLMARGVDRNDIVAGLNRAIAARISSLAENMDLADGICLDGGPALNSGLHRAMGEEMGREVRVLEQ
PQFTVALGAALAIARERGR

Specific function: Required for the activation of (R)-2-hydroxyglutaryl-CoA dehydratase. This protein is extremely sensitive towards oxygen [H]

COG id: COG1924

COG function: function code I; Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yjiL and M.jannaschii MJ0004 and MJ0800 [H]

Homologues:

Organism=Escherichia coli, GI87082426, Length=262, Percent_Identity=37.7862595419847, Blast_Score=134, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002731
- InterPro:   IPR008275 [H]

Pfam domain/function: PF01869 BcrAD_BadFG [H]

EC number: NA

Molecular weight: Translated: 27375; Mature: 27375

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITMGFDLGSAAIKAVMAEEGQAVWYGTMPATAHYVHSCELLFRKGLGERGVAEEDLAGI
CEEECCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCE
AATGYGKGLFSRADKVVNEISANALGAFSLSDGQLRSIINIGGQDVKIIKLWPDGSVADF
ECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCEEEEEECCCCCEEEE
RMNDKCAAGTGRFFEMAERILDAPLADFGSMDRESSSPAEIGSTCAVFAETELISLMARG
ECCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCC
VDRNDIVAGLNRAIAARISSLAENMDLADGICLDGGPALNSGLHRAMGEEMGREVRVLEQ
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCEEECCC
PQFTVALGAALAIARERGR
CCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITMGFDLGSAAIKAVMAEEGQAVWYGTMPATAHYVHSCELLFRKGLGERGVAEEDLAGI
CEEECCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCE
AATGYGKGLFSRADKVVNEISANALGAFSLSDGQLRSIINIGGQDVKIIKLWPDGSVADF
ECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCEEEEEECCCCCEEEE
RMNDKCAAGTGRFFEMAERILDAPLADFGSMDRESSSPAEIGSTCAVFAETELISLMARG
ECCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCC
VDRNDIVAGLNRAIAARISSLAENMDLADGICLDGGPALNSGLHRAMGEEMGREVRVLEQ
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCEEECCC
PQFTVALGAALAIARERGR
CCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8365476; 2659350; 7607244; 11106419; 11243821 [H]