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The map label for this gene is cirA [H]

Identifier: 118579695

GI number: 118579695

Start: 1330595

End: 1332634

Strand: Direct

Name: cirA [H]

Synonym: Ppro_1266

Alternate gene names: 118579695

Gene position: 1330595-1332634 (Clockwise)

Preceding gene: 118579694

Following gene: 118579696

Centisome position: 33.2

GC content: 60.93

Gene sequence:

>2040_bases
ATGAAGCAGTGGTACCTGTATGCGGCCGTTCTGGGCGCGCTTGTGTTGTCCCGTCCGGCCGTGTCGCCGGCGATGGAGCA
GACGGAGACAGCGGAGACGGCGGAGGAGAAACGGAGCAACCTGGCCAGGAAGAAGGAGGCCGATGCCAAGCTGGACGAGA
TCGTGGTCACGGCCACGAGGACGGCGGAGTCCAGAAAGGACATCCCGGCGTCGGTTCACGTTATCAACGAGGAGACCATC
AAGAGCTCTTCGGCCAAGGACGTGGGGGAGCTGCTGGCCGAGGCCGGCATCGGCCATGTGCACAAGTACAACATGGCCCT
TGCCACCAGGATCGAGATCCGTGGCCTGACCACCGACTCCAGCAACGAGGTGGGCAACCGGATCATGGTGCTGGTGAACG
GTAACCGGGCCGGCACCTCCAACATCGCCAAGATCCCGGTGGCGGATATCGAGCGGGTGGAGGTAGTCAAGGGACCCGCC
TCGGTGGTCTACGGCTCCCAGGCCATGGGGGGGGTGATCAACATCATCACCAAGAAGGGGAAGGGGGAGCTGAGCGGCTC
GATCCTGGCCGAAGGGGGCTCCTGGGGCTACTGGAAAACCGCGGCCGAACTGGGGGGGACCAAACACAACGTGGATTTTT
ACGCCACTGCCAGCAAGTCCGAGGCCAAGGATTTCAGCAGCCCCGGCCATGGCCGCATCGAAAACACCCATTACGATACC
GAGGATCTCAGTACGCGTCTCGGCTATACCTTCCTGAAGGATCACCGCATCGCCGTCGGCTTTCAACACTGGGAGACGGA
ACACGGTTCTCCCGGTTACTGGTGGAAACCGGAGCTGAAGAACCACAACGACAAGGAGCGTAACGCCATCGACGTGGAGT
ACGCCAACTCCACCCTGACGGCCAAGTACTACCTGACCCTGAACAAGGATACCTACAACTATCCCAGCAGCACCCCCTAC
TACCAGTATTTCAGTCGTACCCGCTCCCAGGGGGCCAGCCTGCAGAACGTGTTTCCCATCGGCAACCACCGTATCCTGGT
GGGCGCTGAATGGGCCAGGATCGAGCTGGAGTCCCGCAGGACCGACGGGAAAAAGTTGAACAGCCCGGACACCAGAAACG
ACAACTACGCCGTGTTCACCGAGGGAAAACTCGACCTGTTCTCCAACCGGCTGATACTGACTGCCGGCATGCGCTACGAC
TACTTCGACAACAGCATGCTGGCCACGGCAAACGCGATCAACGCCACGGAGGATGTCTCCAAGACCATGGATCACCTGAC
CTTCAGGGGGGGGGTCGTGTACAAGGTCAACGACGCGCTCAGCCTGAGGGGGAGCGTCGGCACCGCCTTCCGCGCCCCGG
CGCCCCTGGAGATCGCGGCTGATTACAACTCCACCGGAACCAAGCATGTGGTGGGCAATCCGGATCTCAAGCCGGAGAAG
AGCATCACCTACGAGGCGGGTATTGACTTCAACTACAAGGAGTTGAAGAGCAGCTTCGCCTTCTTCCACACCGACTTCAG
CGACAAGATCTACCAGTACCGGGTCAGCGGCATCGACTGGAGTTACAAGAACGTTCCCGGCGCCATCATCCAGGGGGTGG
AGATGGATGTCTCCTACGACATGGGGTGGCTGACCGGACTCGACATGGTGTTTCAGCCGTACGCCAACGTGACCTACAAA
ACCAGGTACGAGTCCAGCGACCCGGCGGAGATAGCCGCGACCAAGAGCAGCCGGCTGCTGTACATCCCGGAGTGGACCGG
GGCCTTCGGCATCCGTGCCGCCCGGGAGAACTGGGAGGGGCGGATGGTGTTCAACTACCAGGGAACCGAACGCATCCTCA
GCTATGAGAACAACGCCAACGGCGAGTACACCGACAAGGGGGGCTTTTTGACCGCCAGCATCAAGGGAAGCTACCGGCCG
GTCAAGTCCCTCGAACTCTCCCTGGCGGTCAACAACCTGTTCGACCGCAGGTACGAGTACGTCAACGGCTATGCCATGGC
CGGAAGGACGTTCATCGGCGGCGCCAAGTGGCTGTTCTGA

Upstream 100 bases:

>100_bases
TCATGGGCCATACCATGGCGGGAAGGCGGTCAGTAGGATGCCCTGAGCCGGAAGACCTGTGTGGATGCCGATTATCATGT
GATTCCCGAGGGAGGAAAAG

Downstream 100 bases:

>100_bases
CCGGGGCGCACGGAGTGAACCGAATGCGGGATGAACCGGACGGGGAACCGTCGGAGGTTTCGTGAGGCTGCTGGAGGCGG
CCACACGCGGGTTGTGGAAT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 679; Mature: 679

Protein sequence:

>679_residues
MKQWYLYAAVLGALVLSRPAVSPAMEQTETAETAEEKRSNLARKKEADAKLDEIVVTATRTAESRKDIPASVHVINEETI
KSSSAKDVGELLAEAGIGHVHKYNMALATRIEIRGLTTDSSNEVGNRIMVLVNGNRAGTSNIAKIPVADIERVEVVKGPA
SVVYGSQAMGGVINIITKKGKGELSGSILAEGGSWGYWKTAAELGGTKHNVDFYATASKSEAKDFSSPGHGRIENTHYDT
EDLSTRLGYTFLKDHRIAVGFQHWETEHGSPGYWWKPELKNHNDKERNAIDVEYANSTLTAKYYLTLNKDTYNYPSSTPY
YQYFSRTRSQGASLQNVFPIGNHRILVGAEWARIELESRRTDGKKLNSPDTRNDNYAVFTEGKLDLFSNRLILTAGMRYD
YFDNSMLATANAINATEDVSKTMDHLTFRGGVVYKVNDALSLRGSVGTAFRAPAPLEIAADYNSTGTKHVVGNPDLKPEK
SITYEAGIDFNYKELKSSFAFFHTDFSDKIYQYRVSGIDWSYKNVPGAIIQGVEMDVSYDMGWLTGLDMVFQPYANVTYK
TRYESSDPAEIAATKSSRLLYIPEWTGAFGIRAARENWEGRMVFNYQGTERILSYENNANGEYTDKGGFLTASIKGSYRP
VKSLELSLAVNNLFDRRYEYVNGYAMAGRTFIGGAKWLF

Sequences:

>Translated_679_residues
MKQWYLYAAVLGALVLSRPAVSPAMEQTETAETAEEKRSNLARKKEADAKLDEIVVTATRTAESRKDIPASVHVINEETI
KSSSAKDVGELLAEAGIGHVHKYNMALATRIEIRGLTTDSSNEVGNRIMVLVNGNRAGTSNIAKIPVADIERVEVVKGPA
SVVYGSQAMGGVINIITKKGKGELSGSILAEGGSWGYWKTAAELGGTKHNVDFYATASKSEAKDFSSPGHGRIENTHYDT
EDLSTRLGYTFLKDHRIAVGFQHWETEHGSPGYWWKPELKNHNDKERNAIDVEYANSTLTAKYYLTLNKDTYNYPSSTPY
YQYFSRTRSQGASLQNVFPIGNHRILVGAEWARIELESRRTDGKKLNSPDTRNDNYAVFTEGKLDLFSNRLILTAGMRYD
YFDNSMLATANAINATEDVSKTMDHLTFRGGVVYKVNDALSLRGSVGTAFRAPAPLEIAADYNSTGTKHVVGNPDLKPEK
SITYEAGIDFNYKELKSSFAFFHTDFSDKIYQYRVSGIDWSYKNVPGAIIQGVEMDVSYDMGWLTGLDMVFQPYANVTYK
TRYESSDPAEIAATKSSRLLYIPEWTGAFGIRAARENWEGRMVFNYQGTERILSYENNANGEYTDKGGFLTASIKGSYRP
VKSLELSLAVNNLFDRRYEYVNGYAMAGRTFIGGAKWLF
>Mature_679_residues
MKQWYLYAAVLGALVLSRPAVSPAMEQTETAETAEEKRSNLARKKEADAKLDEIVVTATRTAESRKDIPASVHVINEETI
KSSSAKDVGELLAEAGIGHVHKYNMALATRIEIRGLTTDSSNEVGNRIMVLVNGNRAGTSNIAKIPVADIERVEVVKGPA
SVVYGSQAMGGVINIITKKGKGELSGSILAEGGSWGYWKTAAELGGTKHNVDFYATASKSEAKDFSSPGHGRIENTHYDT
EDLSTRLGYTFLKDHRIAVGFQHWETEHGSPGYWWKPELKNHNDKERNAIDVEYANSTLTAKYYLTLNKDTYNYPSSTPY
YQYFSRTRSQGASLQNVFPIGNHRILVGAEWARIELESRRTDGKKLNSPDTRNDNYAVFTEGKLDLFSNRLILTAGMRYD
YFDNSMLATANAINATEDVSKTMDHLTFRGGVVYKVNDALSLRGSVGTAFRAPAPLEIAADYNSTGTKHVVGNPDLKPEK
SITYEAGIDFNYKELKSSFAFFHTDFSDKIYQYRVSGIDWSYKNVPGAIIQGVEMDVSYDMGWLTGLDMVFQPYANVTYK
TRYESSDPAEIAATKSSRLLYIPEWTGAFGIRAARENWEGRMVFNYQGTERILSYENNANGEYTDKGGFLTASIKGSYRP
VKSLELSLAVNNLFDRRYEYVNGYAMAGRTFIGGAKWLF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=701, Percent_Identity=25.962910128388, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1790405, Length=139, Percent_Identity=32.3741007194245, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786798, Length=381, Percent_Identity=22.3097112860892, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1787723, Length=292, Percent_Identity=24.6575342465753, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 75580; Mature: 75580

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQWYLYAAVLGALVLSRPAVSPAMEQTETAETAEEKRSNLARKKEADAKLDEIVVTATR
CCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
TAESRKDIPASVHVINEETIKSSSAKDVGELLAEAGIGHVHKYNMALATRIEIRGLTTDS
CCCHHCCCCCEEEEECHHHHCCCCHHHHHHHHHHCCCCCEEEECEEEEEEEEEEEECCCC
SNEVGNRIMVLVNGNRAGTSNIAKIPVADIERVEVVKGPASVVYGSQAMGGVINIITKKG
CCCCCCEEEEEEECCCCCCCCEEECCCCCCCEEEEECCCHHEEECCHHHCCEEEEEEECC
KGELSGSILAEGGSWGYWKTAAELGGTKHNVDFYATASKSEAKDFSSPGHGRIENTHYDT
CCCCCCEEEECCCCCCHHHHHHHCCCCCCCEEEEEECCCCCHHHCCCCCCCCCCCCCCCH
EDLSTRLGYTFLKDHRIAVGFQHWETEHGSPGYWWKPELKNHNDKERNAIDVEYANSTLT
HHHHHHHCEEEEECCEEEEEEEECCCCCCCCCCEECCCCCCCCCCCCCEEEEEECCCEEE
AKYYLTLNKDTYNYPSSTPYYQYFSRTRSQGASLQNVFPIGNHRILVGAEWARIELESRR
EEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCEEEEECCEEEEEEECCC
TDGKKLNSPDTRNDNYAVFTEGKLDLFSNRLILTAGMRYDYFDNSMLATANAINATEDVS
CCCCCCCCCCCCCCCEEEEECCCHHHHCCEEEEEECCEEECCCCCEEEECCCCCCHHHHH
KTMDHLTFRGGVVYKVNDALSLRGSVGTAFRAPAPLEIAADYNSTGTKHVVGNPDLKPEK
HHHHHHEECCCEEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCC
SITYEAGIDFNYKELKSSFAFFHTDFSDKIYQYRVSGIDWSYKNVPGAIIQGVEMDVSYD
CEEEECCCCCCHHHHHCCCEEEECCCCCCEEEEEECCCCCCCCCCCHHHHCCEEEEEECC
MGWLTGLDMVFQPYANVTYKTRYESSDPAEIAATKSSRLLYIPEWTGAFGIRAARENWEG
CHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCCEEEEECCCCCCCEEECCCCCCC
RMVFNYQGTERILSYENNANGEYTDKGGFLTASIKGSYRPVKSLELSLAVNNLFDRRYEY
EEEEEECCCCEEEEECCCCCCCEECCCCEEEEEECCCCCCHHHEEEEEHHHHHHHHHHHH
VNGYAMAGRTFIGGAKWLF
HCCEEECCCEEECCCCCCC
>Mature Secondary Structure
MKQWYLYAAVLGALVLSRPAVSPAMEQTETAETAEEKRSNLARKKEADAKLDEIVVTATR
CCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
TAESRKDIPASVHVINEETIKSSSAKDVGELLAEAGIGHVHKYNMALATRIEIRGLTTDS
CCCHHCCCCCEEEEECHHHHCCCCHHHHHHHHHHCCCCCEEEECEEEEEEEEEEEECCCC
SNEVGNRIMVLVNGNRAGTSNIAKIPVADIERVEVVKGPASVVYGSQAMGGVINIITKKG
CCCCCCEEEEEEECCCCCCCCEEECCCCCCCEEEEECCCHHEEECCHHHCCEEEEEEECC
KGELSGSILAEGGSWGYWKTAAELGGTKHNVDFYATASKSEAKDFSSPGHGRIENTHYDT
CCCCCCEEEECCCCCCHHHHHHHCCCCCCCEEEEEECCCCCHHHCCCCCCCCCCCCCCCH
EDLSTRLGYTFLKDHRIAVGFQHWETEHGSPGYWWKPELKNHNDKERNAIDVEYANSTLT
HHHHHHHCEEEEECCEEEEEEEECCCCCCCCCCEECCCCCCCCCCCCCEEEEEECCCEEE
AKYYLTLNKDTYNYPSSTPYYQYFSRTRSQGASLQNVFPIGNHRILVGAEWARIELESRR
EEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCEEEEECCEEEEEEECCC
TDGKKLNSPDTRNDNYAVFTEGKLDLFSNRLILTAGMRYDYFDNSMLATANAINATEDVS
CCCCCCCCCCCCCCCEEEEECCCHHHHCCEEEEEECCEEECCCCCEEEECCCCCCHHHHH
KTMDHLTFRGGVVYKVNDALSLRGSVGTAFRAPAPLEIAADYNSTGTKHVVGNPDLKPEK
HHHHHHEECCCEEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCC
SITYEAGIDFNYKELKSSFAFFHTDFSDKIYQYRVSGIDWSYKNVPGAIIQGVEMDVSYD
CEEEECCCCCCHHHHHCCCEEEECCCCCCEEEEEECCCCCCCCCCCHHHHCCEEEEEECC
MGWLTGLDMVFQPYANVTYKTRYESSDPAEIAATKSSRLLYIPEWTGAFGIRAARENWEG
CHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCCEEEEECCCCCCCEEECCCCCCC
RMVFNYQGTERILSYENNANGEYTDKGGFLTASIKGSYRPVKSLELSLAVNNLFDRRYEY
EEEEEECCCCEEEEECCCCCCCEECCCCEEEEEECCCCCCHHHEEEEEHHHHHHHHHHHH
VNGYAMAGRTFIGGAKWLF
HCCEEECCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]