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The map label for this gene is hlyB [H]

Identifier: 118579650

GI number: 118579650

Start: 1275079

End: 1276713

Strand: Reverse

Name: hlyB [H]

Synonym: Ppro_1221

Alternate gene names: 118579650

Gene position: 1276713-1275079 (Counterclockwise)

Preceding gene: 118579652

Following gene: 118579633

Centisome position: 31.85

GC content: 62.14

Gene sequence:

>1635_bases
ATGACGATGTTCATCACCATCAAGGCAAAACTGATCAGCACCTGCGCAATCATCCTGGCTGGCATTCTGGCCATCTTAGT
CTTCACGCACGTTTCCATCAACCGGATCAAGATCGATGGCCCCGTGTACCATGAGATCGTACGCGGCAAGGATCTTATCG
CCGATATCCTGCCGCCCCCCGAATACATCATCGAATCGTACTTCGTTGTTCTGCGGGCGATGGTGGAGACAGACGATTCC
AAACTCCCCGGCTATCATGAACGGCTGAAGAAACTGCGTGCCGAATACGACCAGCGCCATGACCATTGGGTCAGGGAACT
TCCTCCGGGAAAGGGTAGGACGCTGCTGCTGGAAGAGTCCTACAGGCCGGCGGTGAAGTTCTACAACACGGTGGAAGGGG
AGTTTTTTCCCGCCTTGCGGGCGCACGACCGCACCAGGGCGGAACACCTGCTGCGCGACGTGCTCTCCCCCTCCTATGAG
GCTCACCGGAGCGCCATCGACCAGATCGTTGTTCTGAGCAACGCGGCTAACAGCGAAACGGAACGACGCGCCGCGGCCAT
GCTGCGCACCTCCGAAATCGCTCTGACCTCCATGGGCATGCTGCTCTTCGTTGCGATCCTGGCGGTATTCTACGGTATCG
TACGCAGCATAAACGCCCGACTCACGCAGGCGGTTTCCGTAGCCAACACCATCGCCTCCGGTGACCTGAGCGTTGACGTT
CGGGTTGGTTCGGAAGACGAAACCGGCCAGCTGCTGCGGGCAATGAAGGTCATGGTGGATAACCTGCGCAATATCATCAA
CCAGGTATCCGGAACATCGTCGTTGGTGGCGTTAGCCGCGGACCAACTGCATGCCACCGCCGAACGGACCGCCGGCAACG
CCGAAGAGATCGCCGGCCAGGCCGTAACCGTGGCCACGGCCGGCGAAGAGATGTCAGCCACATCGGGCGACATCGCCCAG
AACTGCCAGATGGCGGCCGAGGGAGCGCAGCACGCTTCGGCCTCGGCCCAAAGCGGCGCCGAGGTCGTTGAAAAGACGGT
GGCGGTGATGGGGCAGATCGCGGCCCGGGTGCAGGAGTCGGCAAAGACCGTGGAGAGTCTTGGGGCACGTAGCAATCAGA
TCGGCGCCATCATCGGCGCCATCGAGGATATCGCCGACCAGACGAACCTGCTGGCATTGAACGCCGCCATCGAGGCGGCC
CGGGCAGGGGAACAGGGGAGAGGCTTCGCGGTGGTTGCCGACGAGGTGCGTGCCCTGGCGGAACGCACCACCCGCGCCAC
ACATGAGATCGATGAGATGATCAAAGCCATCCAGGCTGAGACCGGCGCTGCCGTGGCCGCCATGGAGCAGGGAGTCGATC
AGGTGGAGGCCGGTACCATGGAGGCGGCCCGCTCAGGCGACGCGCTGCGGGACATTCTGGAGCAGATCAACGACGTTGCC
ATGCAGGTCAGCCAGATCGCCACCGCTGCCGAGGAGCAGACCGCCACCACCGGTGAGATAGCCGGCAACATGCAGCAGAT
CACCCAGGTCGTGCGGCAGACATCCCACGGCGCCCAGGAATCCGTCACCGCGGCGGCGCACCTCAGCAGAAACGCCGGAG
AACTGCAGCGGCTGGTACAGCAGTTCAGATTGTAA

Upstream 100 bases:

>100_bases
CTATTCTTGGTCTCATTAAGACCGTTCTCTCCAATCGTTCACTTACCCGCAACGGCATCACAGTTCCCTGTGCGTGCGGC
AATTCCCCCTATGAGGATCA

Downstream 100 bases:

>100_bases
ACTCCAGACAATGAGCCTCCGGATATCCCACCACCAATGACCAAAGCCCCACAAATGTGGGGCTTTGCCGATTCTCTTTG
CCAGCCCCGCTGTTTCCCCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MTMFITIKAKLISTCAIILAGILAILVFTHVSINRIKIDGPVYHEIVRGKDLIADILPPPEYIIESYFVVLRAMVETDDS
KLPGYHERLKKLRAEYDQRHDHWVRELPPGKGRTLLLEESYRPAVKFYNTVEGEFFPALRAHDRTRAEHLLRDVLSPSYE
AHRSAIDQIVVLSNAANSETERRAAAMLRTSEIALTSMGMLLFVAILAVFYGIVRSINARLTQAVSVANTIASGDLSVDV
RVGSEDETGQLLRAMKVMVDNLRNIINQVSGTSSLVALAADQLHATAERTAGNAEEIAGQAVTVATAGEEMSATSGDIAQ
NCQMAAEGAQHASASAQSGAEVVEKTVAVMGQIAARVQESAKTVESLGARSNQIGAIIGAIEDIADQTNLLALNAAIEAA
RAGEQGRGFAVVADEVRALAERTTRATHEIDEMIKAIQAETGAAVAAMEQGVDQVEAGTMEAARSGDALRDILEQINDVA
MQVSQIATAAEEQTATTGEIAGNMQQITQVVRQTSHGAQESVTAAAHLSRNAGELQRLVQQFRL

Sequences:

>Translated_544_residues
MTMFITIKAKLISTCAIILAGILAILVFTHVSINRIKIDGPVYHEIVRGKDLIADILPPPEYIIESYFVVLRAMVETDDS
KLPGYHERLKKLRAEYDQRHDHWVRELPPGKGRTLLLEESYRPAVKFYNTVEGEFFPALRAHDRTRAEHLLRDVLSPSYE
AHRSAIDQIVVLSNAANSETERRAAAMLRTSEIALTSMGMLLFVAILAVFYGIVRSINARLTQAVSVANTIASGDLSVDV
RVGSEDETGQLLRAMKVMVDNLRNIINQVSGTSSLVALAADQLHATAERTAGNAEEIAGQAVTVATAGEEMSATSGDIAQ
NCQMAAEGAQHASASAQSGAEVVEKTVAVMGQIAARVQESAKTVESLGARSNQIGAIIGAIEDIADQTNLLALNAAIEAA
RAGEQGRGFAVVADEVRALAERTTRATHEIDEMIKAIQAETGAAVAAMEQGVDQVEAGTMEAARSGDALRDILEQINDVA
MQVSQIATAAEEQTATTGEIAGNMQQITQVVRQTSHGAQESVTAAAHLSRNAGELQRLVQQFRL
>Mature_543_residues
TMFITIKAKLISTCAIILAGILAILVFTHVSINRIKIDGPVYHEIVRGKDLIADILPPPEYIIESYFVVLRAMVETDDSK
LPGYHERLKKLRAEYDQRHDHWVRELPPGKGRTLLLEESYRPAVKFYNTVEGEFFPALRAHDRTRAEHLLRDVLSPSYEA
HRSAIDQIVVLSNAANSETERRAAAMLRTSEIALTSMGMLLFVAILAVFYGIVRSINARLTQAVSVANTIASGDLSVDVR
VGSEDETGQLLRAMKVMVDNLRNIINQVSGTSSLVALAADQLHATAERTAGNAEEIAGQAVTVATAGEEMSATSGDIAQN
CQMAAEGAQHASASAQSGAEVVEKTVAVMGQIAARVQESAKTVESLGARSNQIGAIIGAIEDIADQTNLLALNAAIEAAR
AGEQGRGFAVVADEVRALAERTTRATHEIDEMIKAIQAETGAAVAAMEQGVDQVEAGTMEAARSGDALRDILEQINDVAM
QVSQIATAAEEQTATTGEIAGNMQQITQVVRQTSHGAQESVTAAAHLSRNAGELQRLVQQFRL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=325, Percent_Identity=32, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1788194, Length=445, Percent_Identity=29.2134831460674, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1787690, Length=352, Percent_Identity=32.6704545454545, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788195, Length=335, Percent_Identity=32.8358208955224, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1789453, Length=362, Percent_Identity=30.3867403314917, Blast_Score=115, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58409; Mature: 58278

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMFITIKAKLISTCAIILAGILAILVFTHVSINRIKIDGPVYHEIVRGKDLIADILPPP
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCHHHHHHCCCCH
EYIIESYFVVLRAMVETDDSKLPGYHERLKKLRAEYDQRHDHWVRELPPGKGRTLLLEES
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
YRPAVKFYNTVEGEFFPALRAHDRTRAEHLLRDVLSPSYEAHRSAIDQIVVLSNAANSET
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHH
ERRAAAMLRTSEIALTSMGMLLFVAILAVFYGIVRSINARLTQAVSVANTIASGDLSVDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
RVGSEDETGQLLRAMKVMVDNLRNIINQVSGTSSLVALAADQLHATAERTAGNAEEIAGQ
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCC
AVTVATAGEEMSATSGDIAQNCQMAAEGAQHASASAQSGAEVVEKTVAVMGQIAARVQES
EEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AKTVESLGARSNQIGAIIGAIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALA
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHH
ERTTRATHEIDEMIKAIQAETGAAVAAMEQGVDQVEAGTMEAARSGDALRDILEQINDVA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
MQVSQIATAAEEQTATTGEIAGNMQQITQVVRQTSHGAQESVTAAAHLSRNAGELQRLVQ
HHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHH
QFRL
HHCC
>Mature Secondary Structure 
TMFITIKAKLISTCAIILAGILAILVFTHVSINRIKIDGPVYHEIVRGKDLIADILPPP
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCHHHHHHCCCCH
EYIIESYFVVLRAMVETDDSKLPGYHERLKKLRAEYDQRHDHWVRELPPGKGRTLLLEES
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
YRPAVKFYNTVEGEFFPALRAHDRTRAEHLLRDVLSPSYEAHRSAIDQIVVLSNAANSET
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHH
ERRAAAMLRTSEIALTSMGMLLFVAILAVFYGIVRSINARLTQAVSVANTIASGDLSVDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
RVGSEDETGQLLRAMKVMVDNLRNIINQVSGTSSLVALAADQLHATAERTAGNAEEIAGQ
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCC
AVTVATAGEEMSATSGDIAQNCQMAAEGAQHASASAQSGAEVVEKTVAVMGQIAARVQES
EEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AKTVESLGARSNQIGAIIGAIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALA
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHH
ERTTRATHEIDEMIKAIQAETGAAVAAMEQGVDQVEAGTMEAARSGDALRDILEQINDVA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
MQVSQIATAAEEQTATTGEIAGNMQQITQVVRQTSHGAQESVTAAAHLSRNAGELQRLVQ
HHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHH
QFRL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]