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The map label for this gene is rnhB

Identifier: 118579525

GI number: 118579525

Start: 1141921

End: 1142580

Strand: Reverse

Name: rnhB

Synonym: Ppro_1092

Alternate gene names: 118579525

Gene position: 1142580-1141921 (Counterclockwise)

Preceding gene: 118579526

Following gene: 118579524

Centisome position: 28.51

GC content: 63.64

Gene sequence:

>660_bases
ATGTCACCCATGCAACAGCGCGAACTCTTCAGCTCGCCCCCCATTGACCTGCTGTTCTTCGAGCAGCAGGCTCTTAAACA
GGGGCACAGGGTCATAGCGGGAATCGACGAAGCCGGCAGGGGCGCGCTCTGCGGTCCGGTGGTGGCAGCGGCCGTGATTC
TTCCCACAGGTATGGCCATTCCGGGCGTGGATGACTCCAAGAAGCTCTCGCCCCGCACACGCGAGCAGCTTTTCGACGAG
ATAATGGCTCGGGCGCTTTCCGTCGGCATCGGTATCGGCACGCCCCAATTGATCGATCGCATCAATATTCTCCAGGCCAC
GCGCCATGCCATGGCGGAGGCCGTAGACATTCTTGCCCCGCGACCGGACATGCTGCTGATCGACGGCATCAGTACCATCG
ACGTCCCGCTCCCCCAGAAGACCATCACCAAGGGGGATTCGCGCTCCCTCACCATCGCGGCAGCATCCATCATCGCCAAG
GTCAGCCGTGACCGCATGCTGACCGAACTGGACCTACTGCATCCCGGCTACGGCTTCGCCAGCCACAAGGGGTACGGCTG
CGCCTCGCACATGGAGGCCATCCGCCGGCTGGGCCCGTCCCCGGTCCACCGTCTGACCTTCCGGGGCGTACGGGAGCACG
TGACGTGTCCCTCTTCCTGA

Upstream 100 bases:

>100_bases
TCTGCGCAAACTGCGCGGCAAGGCAGCCAGGATCCGCGAGAAGAAATACGTACCCATCGCCAAGTAGCACGGAAAGCCCC
GCACCGTCGGGGCTTTTTTC

Downstream 100 bases:

>100_bases
TCACCTTCCTCTCCCTCTACGGAGGGATGCATCTGTATGCGTATGTGCGCATCCAGCGCGCCTTCAGACCCGGCCGCAGG
GTCCTGTTCACCCTGCGCTG

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSPMQQRELFSSPPIDLLFFEQQALKQGHRVIAGIDEAGRGALCGPVVAAAVILPTGMAIPGVDDSKKLSPRTREQLFDE
IMARALSVGIGIGTPQLIDRINILQATRHAMAEAVDILAPRPDMLLIDGISTIDVPLPQKTITKGDSRSLTIAAASIIAK
VSRDRMLTELDLLHPGYGFASHKGYGCASHMEAIRRLGPSPVHRLTFRGVREHVTCPSS

Sequences:

>Translated_219_residues
MSPMQQRELFSSPPIDLLFFEQQALKQGHRVIAGIDEAGRGALCGPVVAAAVILPTGMAIPGVDDSKKLSPRTREQLFDE
IMARALSVGIGIGTPQLIDRINILQATRHAMAEAVDILAPRPDMLLIDGISTIDVPLPQKTITKGDSRSLTIAAASIIAK
VSRDRMLTELDLLHPGYGFASHKGYGCASHMEAIRRLGPSPVHRLTFRGVREHVTCPSS
>Mature_218_residues
SPMQQRELFSSPPIDLLFFEQQALKQGHRVIAGIDEAGRGALCGPVVAAAVILPTGMAIPGVDDSKKLSPRTREQLFDEI
MARALSVGIGIGTPQLIDRINILQATRHAMAEAVDILAPRPDMLLIDGISTIDVPLPQKTITKGDSRSLTIAAASIIAKV
SRDRMLTELDLLHPGYGFASHKGYGCASHMEAIRRLGPSPVHRLTFRGVREHVTCPSS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=182, Percent_Identity=47.2527472527472, Blast_Score=157, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_PELPD (A1AMZ7)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900775.1
- ProteinModelPortal:   A1AMZ7
- SMR:   A1AMZ7
- STRING:   A1AMZ7
- GeneID:   4573734
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1092
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   A1AMZ7
- ProtClustDB:   PRK00015
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 23617; Mature: 23486

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPMQQRELFSSPPIDLLFFEQQALKQGHRVIAGIDEAGRGALCGPVVAAAVILPTGMAI
CCCHHHHHHHCCCCCEEEEECHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCC
PGVDDSKKLSPRTREQLFDEIMARALSVGIGIGTPQLIDRINILQATRHAMAEAVDILAP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RPDMLLIDGISTIDVPLPQKTITKGDSRSLTIAAASIIAKVSRDRMLTELDLLHPGYGFA
CCCEEEECCCCCCCCCCCHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SHKGYGCASHMEAIRRLGPSPVHRLTFRGVREHVTCPSS
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SPMQQRELFSSPPIDLLFFEQQALKQGHRVIAGIDEAGRGALCGPVVAAAVILPTGMAI
CCHHHHHHHCCCCCEEEEECHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCC
PGVDDSKKLSPRTREQLFDEIMARALSVGIGIGTPQLIDRINILQATRHAMAEAVDILAP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RPDMLLIDGISTIDVPLPQKTITKGDSRSLTIAAASIIAKVSRDRMLTELDLLHPGYGFA
CCCEEEECCCCCCCCCCCHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SHKGYGCASHMEAIRRLGPSPVHRLTFRGVREHVTCPSS
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA