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The map label for this gene is kamA [H]

Identifier: 118579512

GI number: 118579512

Start: 1129791

End: 1131113

Strand: Direct

Name: kamA [H]

Synonym: Ppro_1079

Alternate gene names: 118579512

Gene position: 1129791-1131113 (Clockwise)

Preceding gene: 118579511

Following gene: 118579513

Centisome position: 28.19

GC content: 60.09

Gene sequence:

>1323_bases
ATGAGCATATACACCAAAATTCAGCAGGCAATCGCACGGAAAATAGGCAAGAGCACCGAGCTGTCCCACTGGAAGGACTG
GCGCTGGCAGCTGCGCCATGCCATACGGGATATCGCCACCTTTGAACGGCTGCTTGGCATCAAATTCGATGCTGAACGAA
AGCGGGAACTGGAAGAAACCATCGATAAGTTTCCCCTCTCCATAACCCCCTACTACCTCTCCCTGATCGACCGCACGAAC
TATGCCGTCGATCCCGTCTTCCGCCAAGCCTTTCCCTCGCCGGATGAGCTGCAGGTCACCTCCTGCGAACACGAGGACCC
GCTTCACGAGGATGCCGACAGTCCGGTGCCGGGAATAACCCACCGCTATCCCGACCGGGTGCTGTTCCAGGTCAGCAACA
TCTGCTCCATGTACTGCCGCCACTGTACGCGCAAGCGCAAGGTGGGGGACGTGGATTCGATTCCGGGGAAGGACGAGATC
ATGCTGGGGCTGGAGTACATTCGCCGCACCCCGGTGGTCCGCGACGTGCTCCTCTCGGGGGGGGACCCGCTGATGCTTCC
CGACAGCCATCTGGACTGGATCCTGAGAGAACTGCGCGCCATCCCCCATGTGCAGGTGATCCGTATCGGCAGCCGCATGC
CGGTCGTGCTTCCCTACCGCATCACTCCCGGCCTGATCCGCGTTTTGTCCCGGTATCATCCGCTCTGGCTGAACACCCAT
TTCAATCACCCCCGGGAGATCACCACGTCGGCCAGGGAGGCGCTGTCCCGCCTGGCCAATGCCGGCATCCCCCTGGGCAA
CCAGACCGTACTTTTGGCGGGAGTGAACGATTGTCCCATGATCATCAAGACTCTGATGCAGCGACTGGTGGAGAACCGGG
TGCGACCCTACTACCTCTACCAGTGCGATCTTTCCGAGGGACTTTCCCACTTCCGCACGCCGGTGGGCAAGGGGATGGAG
ATCATGGAGAGCCTGGTCGGCCATACCAGCGGTTTCGCCGTGCCGACCTACGTCATCGACGCGCCGGGAGGAGGGGGCAA
GATCCCGGTCATGCCCAACTACCTGATAACCCTGGCAACCAACAAGGTGGTGCTGCGCAACTACGAAGGGGTGATCACCA
CCTACCAGGAGCCGGAGAAGTACGAGGCGGTGTTCTGCGACCGCAACTGCGCCGATTGTCGCCTGGAGCTGAATATGGAA
GGAACCGGAGAGTATTCGGCCGTCGGCATCGAACGCCTGCTCTCCGATTTTCACGAAACCATCTCTCTGACTCCGGAGGA
CAATATCCGCATGAAACGGAGGAGCAATGGCAGACCGGATTGA

Upstream 100 bases:

>100_bases
CGGGAAGAAGCGGAACAGCGGTTCATCCGGGGCGAAACGCTGACTTCTTCCGTGTGAACCGGGCAGGCCCGTTTGCCCGA
AAGACACCCACAGGAGACCT

Downstream 100 bases:

>100_bases
ACTGATCGGGCGCTCGGTGATCCAGCACGGCCCTGGCAATGACCGGGTCTATCTGATGAAGCAGCACCCGGACGATGCTC
CCGCTCTCCCCGAAAAACTG

Product: lysine 2,3-aminomutase YodO family protein

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSIYTKIQQAIARKIGKSTELSHWKDWRWQLRHAIRDIATFERLLGIKFDAERKRELEETIDKFPLSITPYYLSLIDRTN
YAVDPVFRQAFPSPDELQVTSCEHEDPLHEDADSPVPGITHRYPDRVLFQVSNICSMYCRHCTRKRKVGDVDSIPGKDEI
MLGLEYIRRTPVVRDVLLSGGDPLMLPDSHLDWILRELRAIPHVQVIRIGSRMPVVLPYRITPGLIRVLSRYHPLWLNTH
FNHPREITTSAREALSRLANAGIPLGNQTVLLAGVNDCPMIIKTLMQRLVENRVRPYYLYQCDLSEGLSHFRTPVGKGME
IMESLVGHTSGFAVPTYVIDAPGGGGKIPVMPNYLITLATNKVVLRNYEGVITTYQEPEKYEAVFCDRNCADCRLELNME
GTGEYSAVGIERLLSDFHETISLTPEDNIRMKRRSNGRPD

Sequences:

>Translated_440_residues
MSIYTKIQQAIARKIGKSTELSHWKDWRWQLRHAIRDIATFERLLGIKFDAERKRELEETIDKFPLSITPYYLSLIDRTN
YAVDPVFRQAFPSPDELQVTSCEHEDPLHEDADSPVPGITHRYPDRVLFQVSNICSMYCRHCTRKRKVGDVDSIPGKDEI
MLGLEYIRRTPVVRDVLLSGGDPLMLPDSHLDWILRELRAIPHVQVIRIGSRMPVVLPYRITPGLIRVLSRYHPLWLNTH
FNHPREITTSAREALSRLANAGIPLGNQTVLLAGVNDCPMIIKTLMQRLVENRVRPYYLYQCDLSEGLSHFRTPVGKGME
IMESLVGHTSGFAVPTYVIDAPGGGGKIPVMPNYLITLATNKVVLRNYEGVITTYQEPEKYEAVFCDRNCADCRLELNME
GTGEYSAVGIERLLSDFHETISLTPEDNIRMKRRSNGRPD
>Mature_439_residues
SIYTKIQQAIARKIGKSTELSHWKDWRWQLRHAIRDIATFERLLGIKFDAERKRELEETIDKFPLSITPYYLSLIDRTNY
AVDPVFRQAFPSPDELQVTSCEHEDPLHEDADSPVPGITHRYPDRVLFQVSNICSMYCRHCTRKRKVGDVDSIPGKDEIM
LGLEYIRRTPVVRDVLLSGGDPLMLPDSHLDWILRELRAIPHVQVIRIGSRMPVVLPYRITPGLIRVLSRYHPLWLNTHF
NHPREITTSAREALSRLANAGIPLGNQTVLLAGVNDCPMIIKTLMQRLVENRVRPYYLYQCDLSEGLSHFRTPVGKGMEI
MESLVGHTSGFAVPTYVIDAPGGGGKIPVMPNYLITLATNKVVLRNYEGVITTYQEPEKYEAVFCDRNCADCRLELNMEG
TGEYSAVGIERLLSDFHETISLTPEDNIRMKRRSNGRPD

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=328, Percent_Identity=35.3658536585366, Blast_Score=192, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 50297; Mature: 50165

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYTKIQQAIARKIGKSTELSHWKDWRWQLRHAIRDIATFERLLGIKFDAERKRELEET
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
IDKFPLSITPYYLSLIDRTNYAVDPVFRQAFPSPDELQVTSCEHEDPLHEDADSPVPGIT
HHHCCCCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
HRYPDRVLFQVSNICSMYCRHCTRKRKVGDVDSIPGKDEIMLGLEYIRRTPVVRDVLLSG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCC
GDPLMLPDSHLDWILRELRAIPHVQVIRIGSRMPVVLPYRITPGLIRVLSRYHPLWLNTH
CCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCHHHHHHHHHCCCEEEECC
FNHPREITTSAREALSRLANAGIPLGNQTVLLAGVNDCPMIIKTLMQRLVENRVRPYYLY
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEE
QCDLSEGLSHFRTPVGKGMEIMESLVGHTSGFAVPTYVIDAPGGGGKIPVMPNYLITLAT
ECCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEC
NKVVLRNYEGVITTYQEPEKYEAVFCDRNCADCRLELNMEGTGEYSAVGIERLLSDFHET
CEEEEECCCCEEEECCCCCCCEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
ISLTPEDNIRMKRRSNGRPD
EECCCCCCCEEHHCCCCCCC
>Mature Secondary Structure 
SIYTKIQQAIARKIGKSTELSHWKDWRWQLRHAIRDIATFERLLGIKFDAERKRELEET
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
IDKFPLSITPYYLSLIDRTNYAVDPVFRQAFPSPDELQVTSCEHEDPLHEDADSPVPGIT
HHHCCCCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
HRYPDRVLFQVSNICSMYCRHCTRKRKVGDVDSIPGKDEIMLGLEYIRRTPVVRDVLLSG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCC
GDPLMLPDSHLDWILRELRAIPHVQVIRIGSRMPVVLPYRITPGLIRVLSRYHPLWLNTH
CCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCHHHHHHHHHCCCEEEECC
FNHPREITTSAREALSRLANAGIPLGNQTVLLAGVNDCPMIIKTLMQRLVENRVRPYYLY
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEE
QCDLSEGLSHFRTPVGKGMEIMESLVGHTSGFAVPTYVIDAPGGGGKIPVMPNYLITLAT
ECCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEC
NKVVLRNYEGVITTYQEPEKYEAVFCDRNCADCRLELNMEGTGEYSAVGIERLLSDFHET
CEEEEECCCCEEEECCCCCCCEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
ISLTPEDNIRMKRRSNGRPD
EECCCCCCCEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]