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The map label for this gene is pphB [H]

Identifier: 118579480

GI number: 118579480

Start: 1097677

End: 1098558

Strand: Direct

Name: pphB [H]

Synonym: Ppro_1047

Alternate gene names: 118579480

Gene position: 1097677-1098558 (Clockwise)

Preceding gene: 118579471

Following gene: 118579481

Centisome position: 27.39

GC content: 61.45

Gene sequence:

>882_bases
GTGTCTGCACTGCAGGCCATTGCGGGGCGCATCGGTTCCCGCTCATCGGGGGGGCAGGTCGACCTGCTGCGCTACCTCCC
GCTGAGCGAACGGAGGGGGCACCTGTATCTGGTTGGGGACCTGCACGGTGAATACGGCTCTCTGATGCTGGCGCTCAAGG
CTTTGTCGTTCAATCCTGCGCTGGATCGGGTCCTGTTCACGGGTGACATGCATGACCGTGGCAGGAATTCGGCCGCCTGT
CTGGAACTTTTACGCCAGCCCTGGGTCGATTCGGTGCTGGGGAACCATGAACTGATGCTGCTGAACAGTGTCGACGATGA
CGGTTCCCTGTCCAAAACCAGGAACAGCATGTATGCGGGCTGGATGGCCAATGGAGGGGAGTGGATCGAGGAGACGTCGC
GGGAAGAGAGGAGCGCATGGCGCCGGCGCATCTTGGAGCGCGTTCCGCTCTACTGGATCGTTGAGCGCAGGGACGGCAGG
CGGGTGATGGTCTGCCATGCCGAGACCGACCCGCTGCTGCTCCCCGATGTGGTGGGACTCAGGAACATGCCGGTTTCCCT
GGGGGCACTGCACTCAAGCCCCACCCTGTGGGGACGCCACACCCTGGCAGTTAGCGTTGATGAAACCATCTCTTCCCAGC
GGAAAAAACAACTGTTGCCGCCCCTGGAGGGTGCCCTCTTTGCGGTGCATGGGCACAGCCAGCTAAAATTGGCCTCCTGG
GTCGCCAACCGGCTCTTCATCGACACCGGTGCCGTGTACGGGAACCTGTTGACGTTGGTTGATGTGGATCACGCATTGCC
CGGGCGTCCCGGTGGGGTGCAGGCTTGGGATATTGCATCGGAAAAGCTGATCGGCTATGCTGCCACGAATTTGCTGTTCT
GA

Upstream 100 bases:

>100_bases
CAATGAATCCTGGCCTTGCGGACCCCTGCCGCGGCGCGCAGAGGGAGCCGGCCGTGGAGTGCTCTGCGCACCAGTCCCCG
GAGTATGCGCCGTGAACCTG

Downstream 100 bases:

>100_bases
TTCCGTGGCATGGTCAGGGACGTTGCGTGTCCCCGTCCGTTCGCCACTTCCCGCGATGAAGTTTTGTTGATGCTGCTCTG
GAACATTTCAAGGACAGCCT

Product: metallophosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSALQAIAGRIGSRSSGGQVDLLRYLPLSERRGHLYLVGDLHGEYGSLMLALKALSFNPALDRVLFTGDMHDRGRNSAAC
LELLRQPWVDSVLGNHELMLLNSVDDDGSLSKTRNSMYAGWMANGGEWIEETSREERSAWRRRILERVPLYWIVERRDGR
RVMVCHAETDPLLLPDVVGLRNMPVSLGALHSSPTLWGRHTLAVSVDETISSQRKKQLLPPLEGALFAVHGHSQLKLASW
VANRLFIDTGAVYGNLLTLVDVDHALPGRPGGVQAWDIASEKLIGYAATNLLF

Sequences:

>Translated_293_residues
MSALQAIAGRIGSRSSGGQVDLLRYLPLSERRGHLYLVGDLHGEYGSLMLALKALSFNPALDRVLFTGDMHDRGRNSAAC
LELLRQPWVDSVLGNHELMLLNSVDDDGSLSKTRNSMYAGWMANGGEWIEETSREERSAWRRRILERVPLYWIVERRDGR
RVMVCHAETDPLLLPDVVGLRNMPVSLGALHSSPTLWGRHTLAVSVDETISSQRKKQLLPPLEGALFAVHGHSQLKLASW
VANRLFIDTGAVYGNLLTLVDVDHALPGRPGGVQAWDIASEKLIGYAATNLLF
>Mature_292_residues
SALQAIAGRIGSRSSGGQVDLLRYLPLSERRGHLYLVGDLHGEYGSLMLALKALSFNPALDRVLFTGDMHDRGRNSAACL
ELLRQPWVDSVLGNHELMLLNSVDDDGSLSKTRNSMYAGWMANGGEWIEETSREERSAWRRRILERVPLYWIVERRDGRR
VMVCHAETDPLLLPDVVGLRNMPVSLGALHSSPTLWGRHTLAVSVDETISSQRKKQLLPPLEGALFAVHGHSQLKLASWV
ANRLFIDTGAVYGNLLTLVDVDHALPGRPGGVQAWDIASEKLIGYAATNLLF

Specific function: Can hydrolyze phosphorylated Ser-, Thr- or Tyr- substrates in vitro. The natural substrate is unknown [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPP phosphatase family. PP-1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789090, Length=220, Percent_Identity=31.3636363636364, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87081988, Length=233, Percent_Identity=30.9012875536481, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 32437; Mature: 32305

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALQAIAGRIGSRSSGGQVDLLRYLPLSERRGHLYLVGDLHGEYGSLMLALKALSFNPA
CCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCHH
LDRVLFTGDMHDRGRNSAACLELLRQPWVDSVLGNHELMLLNSVDDDGSLSKTRNSMYAG
HHHEEEECCCCCCCCCHHHHHHHHHCCCHHHHHCCCEEEEEECCCCCCCHHHHHHHEEEE
WMANGGEWIEETSREERSAWRRRILERVPLYWIVERRDGRRVMVCHAETDPLLLPDVVGL
EECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEECCCCCEECCHHHCC
RNMPVSLGALHSSPTLWGRHTLAVSVDETISSQRKKQLLPPLEGALFAVHGHSQLKLASW
CCCCEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHH
VANRLFIDTGAVYGNLLTLVDVDHALPGRPGGVQAWDIASEKLIGYAATNLLF
HHHHHEEECCHHHHCEEEEEEEHHCCCCCCCCCEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SALQAIAGRIGSRSSGGQVDLLRYLPLSERRGHLYLVGDLHGEYGSLMLALKALSFNPA
CHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCHH
LDRVLFTGDMHDRGRNSAACLELLRQPWVDSVLGNHELMLLNSVDDDGSLSKTRNSMYAG
HHHEEEECCCCCCCCCHHHHHHHHHCCCHHHHHCCCEEEEEECCCCCCCHHHHHHHEEEE
WMANGGEWIEETSREERSAWRRRILERVPLYWIVERRDGRRVMVCHAETDPLLLPDVVGL
EECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEECCCCCEECCHHHCC
RNMPVSLGALHSSPTLWGRHTLAVSVDETISSQRKKQLLPPLEGALFAVHGHSQLKLASW
CCCCEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHH
VANRLFIDTGAVYGNLLTLVDVDHALPGRPGGVQAWDIASEKLIGYAATNLLF
HHHHHEEECCHHHHCEEEEEEEHHCCCCCCCCCEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11717262; 11677609 [H]