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The map label for this gene is bdhA [H]

Identifier: 118579476

GI number: 118579476

Start: 1093244

End: 1094305

Strand: Reverse

Name: bdhA [H]

Synonym: Ppro_1043

Alternate gene names: 118579476

Gene position: 1094305-1093244 (Counterclockwise)

Preceding gene: 118579477

Following gene: 118579475

Centisome position: 27.3

GC content: 61.21

Gene sequence:

>1062_bases
ATGAAAGCTGCAAAATGGTATGCAAAGAAAGACATTCGAGTTGAAAACGTTCCCGAACCGGCCGCCCCCAAGGCGGGTGA
AGTCAAGATCAAAGTCGCCTGGTTCGGCATCTGCGGTTCCGACCTGCATGAGTACCTGGCCGGTCCGATCTTCATACCCA
CCGAGAACCACCCGCTGACCGGAGCCAAGGCCCCGCTGATCCTCGGCCATGAATTCACCGGCACGGTCGTGGCAGTGGGC
GCCGGCGTAAACAACGTCAAGGTCGGCGACCTGGTGGCGCCCGATGCCTGCCAGCACTGCGGCGAATGCCTCCCCTGCCG
CATGGGCAACTACAATGTCTGCGAAAAACTGGCCTTCACCGGCCTGATGGCCGATGGCGCCTTTGCCGAGTACGTCAATG
TGCCGGCCGAACTCTGCTACGTCCTGCCCCCCAACTTCGACCCCCAGGCGGGCGCGGTCATCGAACCGCTGGCCACCGGC
TTCAAGGCCGTACGCCTGGCCGGTTCCCTGATGGGCGCCACCGTCGTCGTCTTCGGAGCCGGCACCATCGGTCTGGGCAC
CCTGATGTGCGTCAAGGCCTCGGGCGCAGCCCAGATAATCGTGGTGGAAATGTCCGCCGCACGCAAGAAACTGGCCAAGG
AATGCGGCGCAGACATCATCCTCGACCCCAAGGAATGCGATGTGGTCGCGGAGGTCAAGCGGCTGAGCCCCGAAGGCACC
GGCGCCGACGTCTCCTTCGAATGCATCGGCAACAAATTCACCGGCCCCCAGGCCATCGACGTACTGCACAACTGCGGCAA
GGCGGTTATCGTCGGCATCTTCGAAGAGCCCAGCTCTTTCAACTTCTTCAGCCTGAGCGCCACCGACAAGGTCGTCATCG
GCACCCTGGCCTACACCATCGATGACTTCGCCGGCGTAGCCAAGCTGCTGGCAAGCGGCAAGATCAAGGCCGAACCGATG
ATCACCGGCAAAATCTCGCTGGACGACATCGTGGACAAAGGGTTCGAAGAATTGGTTAACAACAAGGATGCCCACATCAA
GATCATCGTCAGCCCGACATAG

Upstream 100 bases:

>100_bases
ATGGTCCGACCATCGCCACGATGGCCGGACAAACCGAGCAGTCAGGTTTCACAGGCAGCGCGCTTATGCGATGACCTATT
CACTACCAAGGAGAGTACGA

Downstream 100 bases:

>100_bases
GCCCCTAACAGATTCGACACCCAAAGGGGAGGGGAGTTCTCTCCCCTCCCCTTTTTCGTTCCGCACTTCGGTGCCAGATA
AACGGGGAGCACTAGCCAAG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Acetoin reductase/2,3-butanediol dehydrogenase; AR/BDH [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKAAKWYAKKDIRVENVPEPAAPKAGEVKIKVAWFGICGSDLHEYLAGPIFIPTENHPLTGAKAPLILGHEFTGTVVAVG
AGVNNVKVGDLVAPDACQHCGECLPCRMGNYNVCEKLAFTGLMADGAFAEYVNVPAELCYVLPPNFDPQAGAVIEPLATG
FKAVRLAGSLMGATVVVFGAGTIGLGTLMCVKASGAAQIIVVEMSAARKKLAKECGADIILDPKECDVVAEVKRLSPEGT
GADVSFECIGNKFTGPQAIDVLHNCGKAVIVGIFEEPSSFNFFSLSATDKVVIGTLAYTIDDFAGVAKLLASGKIKAEPM
ITGKISLDDIVDKGFEELVNNKDAHIKIIVSPT

Sequences:

>Translated_353_residues
MKAAKWYAKKDIRVENVPEPAAPKAGEVKIKVAWFGICGSDLHEYLAGPIFIPTENHPLTGAKAPLILGHEFTGTVVAVG
AGVNNVKVGDLVAPDACQHCGECLPCRMGNYNVCEKLAFTGLMADGAFAEYVNVPAELCYVLPPNFDPQAGAVIEPLATG
FKAVRLAGSLMGATVVVFGAGTIGLGTLMCVKASGAAQIIVVEMSAARKKLAKECGADIILDPKECDVVAEVKRLSPEGT
GADVSFECIGNKFTGPQAIDVLHNCGKAVIVGIFEEPSSFNFFSLSATDKVVIGTLAYTIDDFAGVAKLLASGKIKAEPM
ITGKISLDDIVDKGFEELVNNKDAHIKIIVSPT
>Mature_353_residues
MKAAKWYAKKDIRVENVPEPAAPKAGEVKIKVAWFGICGSDLHEYLAGPIFIPTENHPLTGAKAPLILGHEFTGTVVAVG
AGVNNVKVGDLVAPDACQHCGECLPCRMGNYNVCEKLAFTGLMADGAFAEYVNVPAELCYVLPPNFDPQAGAVIEPLATG
FKAVRLAGSLMGATVVVFGAGTIGLGTLMCVKASGAAQIIVVEMSAARKKLAKECGADIILDPKECDVVAEVKRLSPEGT
GADVSFECIGNKFTGPQAIDVLHNCGKAVIVGIFEEPSSFNFFSLSATDKVVIGTLAYTIDDFAGVAKLLASGKIKAEPM
ITGKISLDDIVDKGFEELVNNKDAHIKIIVSPT

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=328, Percent_Identity=34.4512195121951, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI4501929, Length=375, Percent_Identity=32.8, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI4501933, Length=375, Percent_Identity=33.0666666666667, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI34577061, Length=375, Percent_Identity=32.2666666666667, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI71565154, Length=376, Percent_Identity=31.9148936170213, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI262073058, Length=379, Percent_Identity=29.287598944591, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI71743840, Length=379, Percent_Identity=29.287598944591, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4501939, Length=362, Percent_Identity=30.3867403314917, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI156523966, Length=362, Percent_Identity=30.3867403314917, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1788073, Length=334, Percent_Identity=35.6287425149701, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI226510992, Length=322, Percent_Identity=32.2981366459627, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788075, Length=352, Percent_Identity=31.5340909090909, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787863, Length=315, Percent_Identity=31.1111111111111, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788407, Length=327, Percent_Identity=29.6636085626911, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1790718, Length=308, Percent_Identity=30.1948051948052, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1790045, Length=356, Percent_Identity=27.8089887640449, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786825, Length=399, Percent_Identity=27.5689223057644, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87082125, Length=332, Percent_Identity=29.8192771084337, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786552, Length=342, Percent_Identity=30.9941520467836, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87081918, Length=294, Percent_Identity=29.5918367346939, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1786518, Length=294, Percent_Identity=26.1904761904762, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=337, Percent_Identity=31.1572700296736, Blast_Score=150, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17562878, Length=254, Percent_Identity=32.6771653543307, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25146526, Length=370, Percent_Identity=28.3783783783784, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71997431, Length=372, Percent_Identity=28.2258064516129, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17565904, Length=245, Percent_Identity=31.0204081632653, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71988145, Length=267, Percent_Identity=25.8426966292135, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562584, Length=266, Percent_Identity=25.187969924812, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319258, Length=376, Percent_Identity=35.1063829787234, Blast_Score=218, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6319257, Length=378, Percent_Identity=33.8624338624339, Blast_Score=206, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6319955, Length=328, Percent_Identity=33.8414634146341, Blast_Score=158, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6322619, Length=328, Percent_Identity=33.8414634146341, Blast_Score=158, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323099, Length=344, Percent_Identity=31.6860465116279, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320033, Length=375, Percent_Identity=29.3333333333333, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6319621, Length=229, Percent_Identity=31.4410480349345, Blast_Score=89, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6324486, Length=232, Percent_Identity=28.448275862069, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=324, Percent_Identity=25, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=269, Percent_Identity=25.2788104089219, Blast_Score=76, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17137530, Length=352, Percent_Identity=30.9659090909091, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17737897, Length=352, Percent_Identity=29.8295454545455, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI17737895, Length=302, Percent_Identity=30.4635761589404, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI221457811, Length=320, Percent_Identity=26.875, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45550770, Length=320, Percent_Identity=26.875, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45551930, Length=320, Percent_Identity=26.875, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.4 [H]

Molecular weight: Translated: 37009; Mature: 37009

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAKWYAKKDIRVENVPEPAAPKAGEVKIKVAWFGICGSDLHEYLAGPIFIPTENHPLT
CCCCCCHHCCCCEECCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHCCCEEEECCCCCCC
GAKAPLILGHEFTGTVVAVGAGVNNVKVGDLVAPDACQHCGECLPCRMGNYNVCEKLAFT
CCCCCEEECCCCCCEEEEEECCCCCEEECCEECCHHHHHHCCCCCCCCCCCHHHHHHHHH
GLMADGAFAEYVNVPAELCYVLPPNFDPQAGAVIEPLATGFKAVRLAGSLMGATVVVFGA
HHHCCCCHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEC
GTIGLGTLMCVKASGAAQIIVVEMSAARKKLAKECGADIILDPKECDVVAEVKRLSPEGT
CHHHHHEEEEEECCCCEEEEEEECHHHHHHHHHHCCCCEEECCHHCCHHHHHHHCCCCCC
GADVSFECIGNKFTGPQAIDVLHNCGKAVIVGIFEEPSSFNFFSLSATDKVVIGTLAYTI
CCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCEEEECCCCEEEEEHHHHHH
DDFAGVAKLLASGKIKAEPMITGKISLDDIVDKGFEELVNNKDAHIKIIVSPT
HHHHHHHHHHHCCCEECCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MKAAKWYAKKDIRVENVPEPAAPKAGEVKIKVAWFGICGSDLHEYLAGPIFIPTENHPLT
CCCCCCHHCCCCEECCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHCCCEEEECCCCCCC
GAKAPLILGHEFTGTVVAVGAGVNNVKVGDLVAPDACQHCGECLPCRMGNYNVCEKLAFT
CCCCCEEECCCCCCEEEEEECCCCCEEECCEECCHHHHHHCCCCCCCCCCCHHHHHHHHH
GLMADGAFAEYVNVPAELCYVLPPNFDPQAGAVIEPLATGFKAVRLAGSLMGATVVVFGA
HHHCCCCHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEC
GTIGLGTLMCVKASGAAQIIVVEMSAARKKLAKECGADIILDPKECDVVAEVKRLSPEGT
CHHHHHEEEEEECCCCEEEEEEECHHHHHHHHHHCCCCEEECCHHCCHHHHHHHCCCCCC
GADVSFECIGNKFTGPQAIDVLHNCGKAVIVGIFEEPSSFNFFSLSATDKVVIGTLAYTI
CCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCEEEECCCCEEEEEHHHHHH
DDFAGVAKLLASGKIKAEPMITGKISLDDIVDKGFEELVNNKDAHIKIIVSPT
HHHHHHHHHHHCCCEECCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]