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The map label for this gene is udg [H]

Identifier: 118579456

GI number: 118579456

Start: 1070699

End: 1072057

Strand: Reverse

Name: udg [H]

Synonym: Ppro_1022

Alternate gene names: 118579456

Gene position: 1072057-1070699 (Counterclockwise)

Preceding gene: 118579457

Following gene: 118579455

Centisome position: 26.75

GC content: 61.74

Gene sequence:

>1359_bases
ATGAAAATTTGCATCTTTGGCGCAGGATACGTCGGCCTGGTGGCTGCGGCCTGCTTTGCGGAAAGCGGAAACAACGTCAT
CGCCGTGGACGTGGATGAGGCCAGGGTCGAGGGGCTTAAGCAGGGCATCGTCCCGATCTACGAGCCGGGACTCAAGGAGA
TGATCCTGCGCAACCAGGGAGAGGGGCGCCTCTCCTTCACCACCGACTACGCAGCGGCCGTACAGGCCTCCCTGGTCAAC
TTCATCGCCGTGGGCACCCCACCGGGGGAGGACGGATCGGCCGACCTGAAGTACGTCCTGGGTGTGGCCCGGGAAATCGG
GCGCGCCATGAACGGCTACAAGATCATCGTGGACAAGTCCACCGTCCCGGTGGGCACCGCCGACAGGGTGCGGCACGCCA
TCAGGGAGGAACTGGACCTGCGCAACGCAGACCTTGAATTCGACGTGGTCTCCAACCCGGAATTCCTCAAGGAAGGGGCT
GCCATCGACGACTTCATGAAGCCCGACCGGGTGGTGATCGGCACCGACAACGTGCGCACTGCCGAGTTCATGAAGGAATT
GTACGAGCCGTTCATGCGCAAGAATAACCGCATGATCGTCATGGACATCCGCAGCGCGGAAATGAGCAAGTACGCGGCCA
ACGCCATGCTGGCAACGCGCATCTCCTTCATGAACCAGATCGCCGGGCTGTGCGAATGCATGGGCGCCGACGTGGCAGCC
GTGCGCGAGGGGATCGGTTCCGATTCCCGCATCGGCTACGACTTCCTCTTCCCCGGTCCAGGCTACGGCGGTTCCTGTTT
CCCCAAGGATGTCAAGGCACTGATCAGAACCGGTAAGGAATGCGACTACGACTTCACCCTGCTCAAGGCGGTGGAAGAGG
TCAACGAGCGCCAGAAACAGGTTCTTGCGGACAAACTGATCAGGGCACTGGGCTCGGCGGACGAAAATAAGCCACTGGAG
GGGAGAACCATCGCCTGCTGGGGACTGGCCTTCAAGCCACGCACCGACGACATGCGCGAGGCGCCGGCCATCACCATCAT
CCAGAGCCTCCTGGCCGCCGGAGCTCGGGTACGGGCCCACGACCCGGAGGCCATCGACGAAGCCAGGAAAATCTTCGGCG
ATGCCATCGACTACAGTAACAACCAGTACGATATCCTAGGCGACGCCGATGCCCTGGCAATCATCACCGACTGGAACGAG
TACCGCAATCCGGACTTCGACCGCATCCGGGAAGCCCTGGCCACTCCCCTGATCGTGGATGGCCGCAACCTATATAAACC
GAGCCGCATGGCCTCGGCAGGCTTCCGCTACATCCCGCTGGGACGAAATAGCAACGGCATGTGCGGCGAGGCGAAGTAG

Upstream 100 bases:

>100_bases
TGCAGGGGATTCATGAATCCGCGGAAGTCGCCATGATTGTGATGGAATTTAGGGCCGACAGTATGGTATAGAACTTTGAT
TGTAACTTTGGAGTGAATCA

Downstream 100 bases:

>100_bases
CAGGTGTCAGGCCCCGGGCTTTGGGTGCGGAGATCCAGCCGTACGCCAATTGAGCGAATGAATCAAGAACCTTCGCCATG
ACCGAACGCAGGAACCGTTC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKICIFGAGYVGLVAAACFAESGNNVIAVDVDEARVEGLKQGIVPIYEPGLKEMILRNQGEGRLSFTTDYAAAVQASLVN
FIAVGTPPGEDGSADLKYVLGVAREIGRAMNGYKIIVDKSTVPVGTADRVRHAIREELDLRNADLEFDVVSNPEFLKEGA
AIDDFMKPDRVVIGTDNVRTAEFMKELYEPFMRKNNRMIVMDIRSAEMSKYAANAMLATRISFMNQIAGLCECMGADVAA
VREGIGSDSRIGYDFLFPGPGYGGSCFPKDVKALIRTGKECDYDFTLLKAVEEVNERQKQVLADKLIRALGSADENKPLE
GRTIACWGLAFKPRTDDMREAPAITIIQSLLAAGARVRAHDPEAIDEARKIFGDAIDYSNNQYDILGDADALAIITDWNE
YRNPDFDRIREALATPLIVDGRNLYKPSRMASAGFRYIPLGRNSNGMCGEAK

Sequences:

>Translated_452_residues
MKICIFGAGYVGLVAAACFAESGNNVIAVDVDEARVEGLKQGIVPIYEPGLKEMILRNQGEGRLSFTTDYAAAVQASLVN
FIAVGTPPGEDGSADLKYVLGVAREIGRAMNGYKIIVDKSTVPVGTADRVRHAIREELDLRNADLEFDVVSNPEFLKEGA
AIDDFMKPDRVVIGTDNVRTAEFMKELYEPFMRKNNRMIVMDIRSAEMSKYAANAMLATRISFMNQIAGLCECMGADVAA
VREGIGSDSRIGYDFLFPGPGYGGSCFPKDVKALIRTGKECDYDFTLLKAVEEVNERQKQVLADKLIRALGSADENKPLE
GRTIACWGLAFKPRTDDMREAPAITIIQSLLAAGARVRAHDPEAIDEARKIFGDAIDYSNNQYDILGDADALAIITDWNE
YRNPDFDRIREALATPLIVDGRNLYKPSRMASAGFRYIPLGRNSNGMCGEAK
>Mature_452_residues
MKICIFGAGYVGLVAAACFAESGNNVIAVDVDEARVEGLKQGIVPIYEPGLKEMILRNQGEGRLSFTTDYAAAVQASLVN
FIAVGTPPGEDGSADLKYVLGVAREIGRAMNGYKIIVDKSTVPVGTADRVRHAIREELDLRNADLEFDVVSNPEFLKEGA
AIDDFMKPDRVVIGTDNVRTAEFMKELYEPFMRKNNRMIVMDIRSAEMSKYAANAMLATRISFMNQIAGLCECMGADVAA
VREGIGSDSRIGYDFLFPGPGYGGSCFPKDVKALIRTGKECDYDFTLLKAVEEVNERQKQVLADKLIRALGSADENKPLE
GRTIACWGLAFKPRTDDMREAPAITIIQSLLAAGARVRAHDPEAIDEARKIFGDAIDYSNNQYDILGDADALAIITDWNE
YRNPDFDRIREALATPLIVDGRNLYKPSRMASAGFRYIPLGRNSNGMCGEAK

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=469, Percent_Identity=34.9680170575693, Blast_Score=248, Evalue=8e-66,
Organism=Homo sapiens, GI296040438, Length=375, Percent_Identity=34.4, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI296040443, Length=325, Percent_Identity=33.8461538461538, Blast_Score=165, Evalue=8e-41,
Organism=Escherichia coli, GI1788340, Length=364, Percent_Identity=28.8461538461538, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI48994968, Length=439, Percent_Identity=27.7904328018223, Blast_Score=142, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17560350, Length=466, Percent_Identity=33.9055793991416, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI17136908, Length=469, Percent_Identity=35.3944562899787, Blast_Score=266, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49531; Mature: 49531

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKICIFGAGYVGLVAAACFAESGNNVIAVDVDEARVEGLKQGIVPIYEPGLKEMILRNQG
CEEEEEECCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHCCC
EGRLSFTTDYAAAVQASLVNFIAVGTPPGEDGSADLKYVLGVAREIGRAMNGYKIIVDKS
CCEEEEEHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
TVPVGTADRVRHAIREELDLRNADLEFDVVSNPEFLKEGAAIDDFMKPDRVVIGTDNVRT
CCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCCCH
AEFMKELYEPFMRKNNRMIVMDIRSAEMSKYAANAMLATRISFMNQIAGLCECMGADVAA
HHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VREGIGSDSRIGYDFLFPGPGYGGSCFPKDVKALIRTGKECDYDFTLLKAVEEVNERQKQ
HHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VLADKLIRALGSADENKPLEGRTIACWGLAFKPRTDDMREAPAITIIQSLLAAGARVRAH
HHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCHHHHCHHHHHHHHHHHCCCEEECC
DPEAIDEARKIFGDAIDYSNNQYDILGDADALAIITDWNEYRNPDFDRIREALATPLIVD
CCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCHHHCCCCHHHHHHHHCCCEEEC
GRNLYKPSRMASAGFRYIPLGRNSNGMCGEAK
CCCCCCCHHHHHCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKICIFGAGYVGLVAAACFAESGNNVIAVDVDEARVEGLKQGIVPIYEPGLKEMILRNQG
CEEEEEECCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHCCC
EGRLSFTTDYAAAVQASLVNFIAVGTPPGEDGSADLKYVLGVAREIGRAMNGYKIIVDKS
CCEEEEEHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
TVPVGTADRVRHAIREELDLRNADLEFDVVSNPEFLKEGAAIDDFMKPDRVVIGTDNVRT
CCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCCCH
AEFMKELYEPFMRKNNRMIVMDIRSAEMSKYAANAMLATRISFMNQIAGLCECMGADVAA
HHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VREGIGSDSRIGYDFLFPGPGYGGSCFPKDVKALIRTGKECDYDFTLLKAVEEVNERQKQ
HHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VLADKLIRALGSADENKPLEGRTIACWGLAFKPRTDDMREAPAITIIQSLLAAGARVRAH
HHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCHHHHCHHHHHHHHHHHCCCEEECC
DPEAIDEARKIFGDAIDYSNNQYDILGDADALAIITDWNEYRNPDFDRIREALATPLIVD
CCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCHHHCCCCHHHHHHHHCCCEEEC
GRNLYKPSRMASAGFRYIPLGRNSNGMCGEAK
CCCCCCCHHHHHCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]