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The map label for this gene is atoS [C]

Identifier: 118579341

GI number: 118579341

Start: 953144

End: 955501

Strand: Reverse

Name: atoS [C]

Synonym: Ppro_0904

Alternate gene names: 118579341

Gene position: 955501-953144 (Counterclockwise)

Preceding gene: 118579369

Following gene: 118579340

Centisome position: 23.84

GC content: 60.98

Gene sequence:

>2358_bases
ATGAAAAACCATCTCTGCCCACCAGCCGGAGACGCAACCAGCGGCGCGCCCCTGACACCTCAGCGGAACCCAGCCCAGCC
GAATGAGCCGCCACGCAACGGGTCGCACCGCCTGCCGGAAAGGGAGGGCGGCGGACGGCACTGCCCGCAACCTGGACTGA
AAGACATACTGGCTCGGTATCTGGACCTGTTCGATCTTGCCCCGGTGGGATATGTAACCATCAGCCAGGGGGGAACCGTG
GTGGAGGCCAACCTGACCTTTGCCGCCATGGTCGGCGTCCAGCGGGACAGCCTGGCCGGCGAACCGCTTGAGCGCTTCAT
CACCCCGGAGGAGCATGAAGCATTCCTTGGCCGACGCACACGGCTCCACGAATCGCAGGAAAGGCAGAGCTGGGAGATGC
GCATGCTGCGCGACGACGGCTCCACGTTCTGGGCACAGTTGCAGGCGATCCCGGAGCGGGAGGGAGAATCATGGATCACA
CTGGACGACATCACCGCGCGTAAACGGGACGAGTCTGATCTGGAGCTGAAGAGTTTCACCCTGGACAACCTGGCCGAAGA
GGTGCTCTGGCTGGCCGCCGACGGCACGATCTGGAACATAAACCAAGTGGCCTGCGAAAAGCTGGGCTACAACCGGGATG
AGTTGCTGAACCTCTCCGTCATGGACATCAATCCGCAGATGACAAAGGAAGGATGGCGCTCCTTCTGGGAGGAGCTGAAA
CAGACGGGCAACCTAAAATTAGAGTCGTCCCACCGGACACGGGACGGCCGCTGCTACCCCACCGAGGTCGTCGCCAACTA
TTTCAACCGCAACGGCTTCGAATACTGCTACTCCATCGTGCGCGATATCACCGCGCACAAAAACCTGGAAAAGGCTCTCC
AGGACAGCGAAGAGCAGTTCCGGACCCTCTGCAACTCGGCCCCCATCGGTATTTTCAGCGCCGACCGCGAGGGGAACAGC
ATTCTCAGCAACCCGCGCTGGGAAGAGATCGCCGGACTGTCGGCCGCGGAGTGCATCGGCAAGGGGTGGACCAGGGCCAT
CCACCCCGATGACCGCGAAGAACAGGCCAAAACCTGGCTGGAGGCCATGAGCACCGGGCGGGTCTATTCCCACGAATACC
GCCTGCTGACCCCCCTGGGAAAGACCATCTGGGTGCGGGCATTGGCCAACCCCATCAAGGATCCGGACGGCACGGTGCTG
GGCTATGTCTGGACCGTGGAAGACATCACCGAGTTGCAGCAGTCGCGCCAGGAGATCCTGAAAACCCAGAAGCTGGAGTC
GCTGGGAGTGCTGGCGGGAGGCATCGCCCACGACTTCAACAACATCCTGACCGCAATTCTCGGCAACATTTCCCTGGCAC
GCCTGCAACTCAATGACACGGCGAAGGTCACCAAACGCCTGGAGGAGGCTGAAACGGCAACCACCCGCGCCAAGGACCTG
ACACGTCAGTTGATCACCTTTGCCCGGGGAGGCGAGCCGCTCAAAAAGAACATCGACGTTTCCAGCCTGCTCAGGGAGGC
CACCGATTTTGCCCTGCACGGCTCCAACGTCAAATGCCGCTTCGACCTGCCGGACGACATCTGGATGGTGGAGGCGGACG
AGGCGCAACTGAGCCAGGTCATCCACAACCTGGTGTTCAACGCGATCCAGGCCATGCCGGGAGGGGGAACCATCAGCATA
GGGGCGAGCAACGTCGTCTCCCAAGAGGGGGGGAGGAAGTTCGTCAAAATCTCCGTTACGGACACCGGAACCGGAATACC
CGCCCACCACATGCAGCAGATTTTCGACCCGTACTTCAGCACCAAGGAAAACAGTATCGGCCTGGGCCTGGCCACCTGCC
ACTCGATTCTCAAGAAACATGGCGGAAAGATACGGGCAGCCTCCACCCTGGGAAGGGGAAGCACGTTTCTCGTCTCCCTG
CCCGCAGCGGATCAGGCCGACGAAGCGCCCTCCCCTAGTGCGGCCGAAGGATCAAACACCAGAAGGCATATACTGGTAAT
GGATGACGAAGAGATGATCAGGGAGTTGGCCGAGGCAATACTGACCGAGTTCGGATACTCGGTGGAATGCGTCGAAAGCG
GCGCCCAGGCCATAGAACTCTACGCCGCGAGGAAAGAAGAGAACAGACCCTTCTCAGCCGTTATCCTGGACCTGACCATC
CCCGGCGGGATCGGCGGCAGGGAGACCATGGAAAAGCTCCGCAGCCTGGATCCCCATGTCAGGGCGATCGTATCCAGCGG
CTATTCCGATGACCCGGTAGTGGCCAATTTCCGGGAGCACGGTTTCAGCGCGGTACTCAGCAAACCATACCGGCCCCAGG
AAATGGGCAGGGTGCTGCAGGAGCTGTTCGCGCCTTAA

Upstream 100 bases:

>100_bases
AACATTGTATACTTCCTGGCGTAAACGGCGTTCGTTTTCTATTGGCGGAGCAGCTGCCCCGATTCCAAAACCTACGCCAA
CGGCACCTGAGGAGCATGCA

Downstream 100 bases:

>100_bases
GCAGCCGGCCGCAGAGGCCAGCCCAGCGGAACACAGATTCCATTTGACACACCCCGGAAAAGCAGGCACATATAACAATT
TCAATTCCCTAAAACGTCCT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MKNHLCPPAGDATSGAPLTPQRNPAQPNEPPRNGSHRLPEREGGGRHCPQPGLKDILARYLDLFDLAPVGYVTISQGGTV
VEANLTFAAMVGVQRDSLAGEPLERFITPEEHEAFLGRRTRLHESQERQSWEMRMLRDDGSTFWAQLQAIPEREGESWIT
LDDITARKRDESDLELKSFTLDNLAEEVLWLAADGTIWNINQVACEKLGYNRDELLNLSVMDINPQMTKEGWRSFWEELK
QTGNLKLESSHRTRDGRCYPTEVVANYFNRNGFEYCYSIVRDITAHKNLEKALQDSEEQFRTLCNSAPIGIFSADREGNS
ILSNPRWEEIAGLSAAECIGKGWTRAIHPDDREEQAKTWLEAMSTGRVYSHEYRLLTPLGKTIWVRALANPIKDPDGTVL
GYVWTVEDITELQQSRQEILKTQKLESLGVLAGGIAHDFNNILTAILGNISLARLQLNDTAKVTKRLEEAETATTRAKDL
TRQLITFARGGEPLKKNIDVSSLLREATDFALHGSNVKCRFDLPDDIWMVEADEAQLSQVIHNLVFNAIQAMPGGGTISI
GASNVVSQEGGRKFVKISVTDTGTGIPAHHMQQIFDPYFSTKENSIGLGLATCHSILKKHGGKIRAASTLGRGSTFLVSL
PAADQADEAPSPSAAEGSNTRRHILVMDDEEMIRELAEAILTEFGYSVECVESGAQAIELYAARKEENRPFSAVILDLTI
PGGIGGRETMEKLRSLDPHVRAIVSSGYSDDPVVANFREHGFSAVLSKPYRPQEMGRVLQELFAP

Sequences:

>Translated_785_residues
MKNHLCPPAGDATSGAPLTPQRNPAQPNEPPRNGSHRLPEREGGGRHCPQPGLKDILARYLDLFDLAPVGYVTISQGGTV
VEANLTFAAMVGVQRDSLAGEPLERFITPEEHEAFLGRRTRLHESQERQSWEMRMLRDDGSTFWAQLQAIPEREGESWIT
LDDITARKRDESDLELKSFTLDNLAEEVLWLAADGTIWNINQVACEKLGYNRDELLNLSVMDINPQMTKEGWRSFWEELK
QTGNLKLESSHRTRDGRCYPTEVVANYFNRNGFEYCYSIVRDITAHKNLEKALQDSEEQFRTLCNSAPIGIFSADREGNS
ILSNPRWEEIAGLSAAECIGKGWTRAIHPDDREEQAKTWLEAMSTGRVYSHEYRLLTPLGKTIWVRALANPIKDPDGTVL
GYVWTVEDITELQQSRQEILKTQKLESLGVLAGGIAHDFNNILTAILGNISLARLQLNDTAKVTKRLEEAETATTRAKDL
TRQLITFARGGEPLKKNIDVSSLLREATDFALHGSNVKCRFDLPDDIWMVEADEAQLSQVIHNLVFNAIQAMPGGGTISI
GASNVVSQEGGRKFVKISVTDTGTGIPAHHMQQIFDPYFSTKENSIGLGLATCHSILKKHGGKIRAASTLGRGSTFLVSL
PAADQADEAPSPSAAEGSNTRRHILVMDDEEMIRELAEAILTEFGYSVECVESGAQAIELYAARKEENRPFSAVILDLTI
PGGIGGRETMEKLRSLDPHVRAIVSSGYSDDPVVANFREHGFSAVLSKPYRPQEMGRVLQELFAP
>Mature_785_residues
MKNHLCPPAGDATSGAPLTPQRNPAQPNEPPRNGSHRLPEREGGGRHCPQPGLKDILARYLDLFDLAPVGYVTISQGGTV
VEANLTFAAMVGVQRDSLAGEPLERFITPEEHEAFLGRRTRLHESQERQSWEMRMLRDDGSTFWAQLQAIPEREGESWIT
LDDITARKRDESDLELKSFTLDNLAEEVLWLAADGTIWNINQVACEKLGYNRDELLNLSVMDINPQMTKEGWRSFWEELK
QTGNLKLESSHRTRDGRCYPTEVVANYFNRNGFEYCYSIVRDITAHKNLEKALQDSEEQFRTLCNSAPIGIFSADREGNS
ILSNPRWEEIAGLSAAECIGKGWTRAIHPDDREEQAKTWLEAMSTGRVYSHEYRLLTPLGKTIWVRALANPIKDPDGTVL
GYVWTVEDITELQQSRQEILKTQKLESLGVLAGGIAHDFNNILTAILGNISLARLQLNDTAKVTKRLEEAETATTRAKDL
TRQLITFARGGEPLKKNIDVSSLLREATDFALHGSNVKCRFDLPDDIWMVEADEAQLSQVIHNLVFNAIQAMPGGGTISI
GASNVVSQEGGRKFVKISVTDTGTGIPAHHMQQIFDPYFSTKENSIGLGLATCHSILKKHGGKIRAASTLGRGSTFLVSL
PAADQADEAPSPSAAEGSNTRRHILVMDDEEMIRELAEAILTEFGYSVECVESGAQAIELYAARKEENRPFSAVILDLTI
PGGIGGRETMEKLRSLDPHVRAIVSSGYSDDPVVANFREHGFSAVLSKPYRPQEMGRVLQELFAP

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=369, Percent_Identity=27.10027100271, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1790436, Length=251, Percent_Identity=35.0597609561753, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI48994928, Length=500, Percent_Identity=22.8, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1786600, Length=370, Percent_Identity=23.2432432432432, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=27.1929824561404, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=26.6129032258064, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87081816, Length=390, Percent_Identity=24.1025641025641, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI145693157, Length=289, Percent_Identity=25.2595155709343, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790300, Length=262, Percent_Identity=26.7175572519084, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788393, Length=221, Percent_Identity=28.5067873303167, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87084; Mature: 87084

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNHLCPPAGDATSGAPLTPQRNPAQPNEPPRNGSHRLPEREGGGRHCPQPGLKDILARY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LDLFDLAPVGYVTISQGGTVVEANLTFAAMVGVQRDSLAGEPLERFITPEEHEAFLGRRT
HHHHHCCCCCEEEEECCCEEEEECCEEEHHHCCCHHCCCCCCHHHCCCCCHHHHHHHHHH
RLHESQERQSWEMRMLRDDGSTFWAQLQAIPEREGESWITLDDITARKRDESDLELKSFT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCHHHCCCCCCCCHHHHHH
LDNLAEEVLWLAADGTIWNINQVACEKLGYNRDELLNLSVMDINPQMTKEGWRSFWEELK
HHHHHHHHEEEECCCCEECHHHHHHHHHCCCHHHEEEEEEEECCHHHHHHHHHHHHHHHH
QTGNLKLESSHRTRDGRCYPTEVVANYFNRNGFEYCYSIVRDITAHKNLEKALQDSEEQF
HCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHH
RTLCNSAPIGIFSADREGNSILSNPRWEEIAGLSAAECIGKGWTRAIHPDDREEQAKTWL
HHHHCCCCCCEEECCCCCCCCCCCCCHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHH
EAMSTGRVYSHEYRLLTPLGKTIWVRALANPIKDPDGTVLGYVWTVEDITELQQSRQEIL
HHHHCCCEEECCEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHHHHHHH
KTQKLESLGVLAGGIAHDFNNILTAILGNISLARLQLNDTAKVTKRLEEAETATTRAKDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
TRQLITFARGGEPLKKNIDVSSLLREATDFALHGSNVKCRFDLPDDIWMVEADEAQLSQV
HHHHHHHHCCCCCHHHCCCHHHHHHHHHHHEEECCCEEEEECCCCCEEEEECCHHHHHHH
IHNLVFNAIQAMPGGGTISIGASNVVSQEGGRKFVKISVTDTGTGIPAHHMQQIFDPYFS
HHHHHHHHHHCCCCCCEEEECCCHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHC
TKENSIGLGLATCHSILKKHGGKIRAASTLGRGSTFLVSLPAADQADEAPSPSAAEGSNT
CCCCCCCCHHHHHHHHHHHCCCCEEEEHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
RRHILVMDDEEMIRELAEAILTEFGYSVECVESGAQAIELYAARKEENRPFSAVILDLTI
CEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEEC
PGGIGGRETMEKLRSLDPHVRAIVSSGYSDDPVVANFREHGFSAVLSKPYRPQEMGRVLQ
CCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCEEHHHHHHCHHHHHCCCCCHHHHHHHHH
ELFAP
HHHCC
>Mature Secondary Structure
MKNHLCPPAGDATSGAPLTPQRNPAQPNEPPRNGSHRLPEREGGGRHCPQPGLKDILARY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LDLFDLAPVGYVTISQGGTVVEANLTFAAMVGVQRDSLAGEPLERFITPEEHEAFLGRRT
HHHHHCCCCCEEEEECCCEEEEECCEEEHHHCCCHHCCCCCCHHHCCCCCHHHHHHHHHH
RLHESQERQSWEMRMLRDDGSTFWAQLQAIPEREGESWITLDDITARKRDESDLELKSFT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCHHHCCCCCCCCHHHHHH
LDNLAEEVLWLAADGTIWNINQVACEKLGYNRDELLNLSVMDINPQMTKEGWRSFWEELK
HHHHHHHHEEEECCCCEECHHHHHHHHHCCCHHHEEEEEEEECCHHHHHHHHHHHHHHHH
QTGNLKLESSHRTRDGRCYPTEVVANYFNRNGFEYCYSIVRDITAHKNLEKALQDSEEQF
HCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHH
RTLCNSAPIGIFSADREGNSILSNPRWEEIAGLSAAECIGKGWTRAIHPDDREEQAKTWL
HHHHCCCCCCEEECCCCCCCCCCCCCHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHH
EAMSTGRVYSHEYRLLTPLGKTIWVRALANPIKDPDGTVLGYVWTVEDITELQQSRQEIL
HHHHCCCEEECCEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHHHHHHH
KTQKLESLGVLAGGIAHDFNNILTAILGNISLARLQLNDTAKVTKRLEEAETATTRAKDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
TRQLITFARGGEPLKKNIDVSSLLREATDFALHGSNVKCRFDLPDDIWMVEADEAQLSQV
HHHHHHHHCCCCCHHHCCCHHHHHHHHHHHEEECCCEEEEECCCCCEEEEECCHHHHHHH
IHNLVFNAIQAMPGGGTISIGASNVVSQEGGRKFVKISVTDTGTGIPAHHMQQIFDPYFS
HHHHHHHHHHCCCCCCEEEECCCHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHC
TKENSIGLGLATCHSILKKHGGKIRAASTLGRGSTFLVSLPAADQADEAPSPSAAEGSNT
CCCCCCCCHHHHHHHHHHHCCCCEEEEHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
RRHILVMDDEEMIRELAEAILTEFGYSVECVESGAQAIELYAARKEENRPFSAVILDLTI
CEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEEC
PGGIGGRETMEKLRSLDPHVRAIVSSGYSDDPVVANFREHGFSAVLSKPYRPQEMGRVLQ
CCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCEEHHHHHHCHHHHHCCCCCHHHHHHHHH
ELFAP
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA